Review of the antiviral potential of melatonin through analysis of In Silico, In Vitro, animal, and clinical studies. Authors identify 20 relevant studies showing evidence that melatonin has strong antiviral properties. In silico studies show melatonin as a candidate against SARS-CoV-2 that could reduce respiratory responses. Cell culture experiments reveal multifaceted antiviral effects on respiratory syncytial virus and other viruses. Animal studies demonstrate reduced mortality and viral replication with melatonin treatment of infections including COVID-19.
Reviews covering melatonin for COVID-19 include1-20.
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