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All Studies   Meta Analysis    Recent:   

Assessing the antiviral potential of melatonin: A comprehensive systematic review

Alomari et al., Reviews in Medical Virology, doi:10.1002/rmv.2499
Dec 2023  
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Melatonin for COVID-19
10th treatment shown to reduce risk in December 2020
 
*, now known with p = 0.0000002 from 18 studies.
Lower risk for mortality, ventilation, and recovery.
No treatment is 100% effective. Protocols combine complementary and synergistic treatments. * >10% efficacy in meta analysis with ≥3 clinical studies.
3,800+ studies for 60+ treatments. c19early.org
Review of the antiviral potential of melatonin through analysis of In Silico, In Vitro, animal, and clinical studies. Authors identify 20 relevant studies showing evidence that melatonin has strong antiviral properties. In silico studies show melatonin as a candidate against SARS-CoV-2 that could reduce respiratory responses. Cell culture experiments reveal multifaceted antiviral effects on respiratory syncytial virus and other viruses. Animal studies demonstrate reduced mortality and viral replication with melatonin treatment of infections including COVID-19.
Reviews covering melatonin for COVID-19 include Alomari, Behl, Camp, Castle, Charaa, Cross, DiNicolantonio, Hosseinzadeh, Langen, Lempesis, Loh, Ramos, Reiter, Reiter (B), Shneider, Tan, Zhang.
Alomari et al., 21 Dec 2023, peer-reviewed, 6 authors.
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Please send us corrections, updates, or comments. c19early involves the extraction of 100,000+ datapoints from thousands of papers. Community updates help ensure high accuracy. Vaccines and treatments are complementary. All practical, effective, and safe means should be used based on risk/benefit analysis. No treatment, vaccine, or intervention is 100% available and effective for all current and future variants. We do not provide medical advice. Before taking any medication, consult a qualified physician who can provide personalized advice and details of risks and benefits based on your medical history and situation. FLCCC and WCH provide treatment protocols.
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