Quercetin for COVID-19
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Discussion of the potential of quercetin for persistent COVID-19 symptoms resulting from oxidative stress. Authors explain how COVID-19 leads to oxidative stress through inflammation, cytokine storms, and coagulation abnormalities. Quercetin is a naturally occurring flavonoid antioxidant that can neutralize free radicals, inhibit viral enzymes, reduce platelet aggregation, and have immunoprotective effects. Studies show quercetin inhibits replication of various viruses. Authors suggest a mixture of quercetin and vitamin C could disrupt SARS-CoV-2 entry, replication, and assembly while strengthening the immune response. Authors note the challenges of quercetin's bioavailability indicating that formulations for improved bioavailability are important.
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Matías-Pérez et al., 26 Dec 2023, peer-reviewed, 5 authors.