The COVID-19 epidemic has put health systems around the world in distress, at the same time stimulating global research in an attempt to discover new therapeutic strategies against this virus. In this opinion we analyze the characteristics of a flavonoid, quercetin, trying to better understand its usefulness in the treatment of coronavirus infection.

Conflicts of Interest The author declared no conflict of interest. Author Contribution Magro VM was the primary researcher and wrote the manuscript. Magro VM provided research and editing assistance to the manuscript. Magro VM contributed to overall article design, data collection as well as revising and approving the manuscript. Abbreviation List 3CL pro , 3-chymotrypsin-like protease ACE2, Angiotensin-converting enzyme 2 Nrf2, Nuclear factor erythroid-derived 2-like 2 PL pro , Papain-like protease

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