In vitro potential antiviral SARS-CoV-19- activity of natural product thymohydroquinone and dithymoquinone from Nigella sativa
Eman R Esharkawy, Faisal Almalki, Taibi Ben Hadda
Bioorganic Chemistry, doi:10.1016/j.bioorg.2021.105587
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Conclusion: The current study highlight in vitro antiviral studies on two compounds from three major compounds in Nigela Sativa depending on bioinformatic analysis, which reveals the importance of three major compounds (TQ, DTQ, and HTQ), as antiviral agents. in vitro antiviral screening on two compounds (DTQ and HTQ) showed the tested drugs exhibited a promising in vitro activity against COVID-19, and have promising antiviral activities, further investigations in clinical trials to determine actual in vivo activity in the treatment of COVID-19 have recommended.
Conflict of interest: The authors declare any conflict of interest.
Conflict of interest: The author sdeclare any conflict of interest
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