The Role of Vitamin D in the Age of COVID-19: A Systematic Review and Meta-Analysis
Ghasemian et al.,
The Role of Vitamin D in the Age of COVID-19: A Systematic Review and Meta-Analysis,
The International Journal of Clinical Practice, doi:10.1111/ijcp.14675 (meta analysis)
Systematic review and meta analysis of 23 studies, finding significantly higher risk of COVID-19 cases and severity with vitamin D deficiency. Mortality risk was higher with deficiency, but not reaching statistical significance, OR 1.6 [0.5-4.4].
Currently there are
107 vitamin D studies and meta analysis shows:
Ghasemian et al., 29 Jul 2021, peer-reviewed, 25 authors.
Abstract: Accepted Article
The Role of Vitamin D in the Age of COVID-19: A Systematic Review and
Meta-Analysis
Roya Ghasemian1, Amir Shamshirian2,3*, Keyvan Heydari3,4, Mohammad Malekan4, Reza AlizadehNavaei3, Mohammad Ali Ebrahimzadeh5, Majid Ebrahimi Warkiani6,7, Hamed Jafarpour4, Sajad Razavi
Bazaz6,
Arash
Rezaei
Shahmirzadi8,
Mehrdad
Khodabandeh9,
Benyamin
Seyfari10,
Alireza
Motamedzadeh11, Ehsan Dadgostar12, Marzieh Aalinezhad13, Meghdad Sedaghat14, Nazanin Razzaghi8,
Bahman Zarandi15, Anahita Asadi5, Vahid Yaghoubi Naei16, Reza Beheshti5, Amirhossein Hessami2, Soheil
Azizi17, Ali Reza Mohseni17,18, Danial Shamshirian19*
1. Antimicrobial Resistance Research Center, Department of Infectious Diseases, Mazandaran University of Medical
Sciences, Sari, Iran.
2. Department of Medical Laboratory Sciences, Student Research Committee, School of Allied Medical Science,
Mazandaran University of Medical Sciences, Sari, Iran.
3. Gastrointestinal Cancer Research Center, Mazandaran University of Medical Sciences, Sari, Iran.
4. Student Research Committee, School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.
5. Pharmaceutical Sciences Research Center, Department of Medicinal Chemistry, School of Pharmacy, Mazandaran
University of Medical Science, Sari, Iran.
6. School of Biomedical Engineering, University of Technology Sydney, Sydney, Ultimo, NSW, 2007, Australia.
7. Institute of Molecular Medicine, Sechenov First Moscow State University, Moscow, 119991, Russia.
8. Student Research Committee, Golestan University of Medical Sciences, Gorgan, Iran.
9. Neuromusculoskeletal Research Center, Department of Physical Medicine and Rehabilitation, Iran University of
Medical Sciences, Tehran, Iran.
10. Department of Surgery, Faculty of Medicine, Kashan University of Medical Sciences, Kashan, Iran.
11. Department of Internal Medicine, Faculty of Medicine, Kashan University of Medical Sciences, Kashan, Iran.
12. Halal Research Center of IRI, FDA, Tehran, Iran.
13. Department of Radiology, Isfahan University of Medical Sciences, Isfahan, I.R. Iran.
14. Department of Internal Medicine, Imam Hossein Hospital, Shahid Beheshti University of Medical Sciences,
Tehran, Iran.
15. Student Research Committee, Iran University of Medical Sciences, Tehran, Iran.
16. Immunology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
17. Department of Medical Laboratory Sciences, School of Allied Medical Science, Mazandaran University of
Medical Sciences, Sari, Iran.
This article has been accepted for publication and undergone full peer review but has not been
through the copyediting, typesetting, pagination and proofreading process, which may lead to
differences between this version and the Version of Record. Please cite this article as doi:
10.1111/ijcp.14675
This article is protected by copyright. All rights reserved
Accepted Article
18. Thalassemia Research Center, Hemoglobinopathy Institute, Mazandaran University of Medical Sciences, Sari,
Iran.
19. Chronic Respiratory Diseases Research Center, National Research Institute of Tuberculosis and Lung Diseases
(NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Corresponding authors:
1. Danial Shamshirian, Chronic Respiratory Diseases Research Center, National Research Institute of Tuberculosis
and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran.
E-Mail: shamshirian@sbmu.ac.ir
Tel: +98 912 640 6146
2. Amir Shamshirian;..
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