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All Studies   Meta Analysis    Recent:   

The Role of Vitamin D in the Age of COVID-19: A Systematic Review and Meta-Analysis

Ghasemian et al., The International Journal of Clinical Practice, doi:10.1111/ijcp.14675
Jul 2021  
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Vitamin D for COVID-19
8th treatment shown to reduce risk in October 2020
 
*, now known with p < 0.00000000001 from 120 studies, recognized in 9 countries.
No treatment is 100% effective. Protocols combine complementary and synergistic treatments. * >10% efficacy in meta analysis with ≥3 clinical studies.
4,200+ studies for 70+ treatments. c19early.org
Systematic review and meta analysis of 23 studies, finding significantly higher risk of COVID-19 cases and severity with vitamin D deficiency. Mortality risk was higher with deficiency, but not reaching statistical significance, OR 1.6 [0.5-4.4].
15 meta analyses show significant improvements with vitamin D treatment for mortality1-10, mechanical ventilation1,6,7,11,12, ICU admission1,3,6,7,10-14, hospitalization5, severity2,4,6,15, and cases8,14,15.
Currently there are 120 vitamin D treatment for COVID-19 studies, showing 36% lower mortality [28‑43%], 16% lower ventilation [-7‑34%], 46% lower ICU admission [28‑60%], 19% lower hospitalization [9‑29%], and 17% fewer cases [9‑24%].
Ghasemian et al., 29 Jul 2021, peer-reviewed, 25 authors.
This PaperVitamin DAll
The role of vitamin D in the age of COVID‐19: A systematic review and meta‐analysis
Roya Ghasemian, Amir Danial Shamshirian, Keyvan Heydari, Mohammad Malekan, Reza Alizadeh‐navaei, Mohammad Ali Ebrahimzadeh, Majid Ebrahimi Warkiani, Hamed Jafarpour, Sajad Razavi Bazaz, Arash Rezaei Shahmirzadi, Mehrdad Khodabandeh, Benyamin Seyfari, Alireza Motamedzadeh, Ehsan Dadgostar, Marzieh Aalinezhad, Meghdad Sedaghat, Nazanin Razzaghi, Bahman Zarandi, Anahita Asadi, Vahid Yaghoubi Naei, Reza Beheshti, Amirhossein Hessami, Soheil Azizi, Ali Reza Mohseni, Danial Shamshirian
International Journal of Clinical Practice, doi:10.1111/ijcp.14675
This article has been accepted for publication and undergone full peer review but has not been through the copyediting, typesetting, pagination and proofreading process, which may lead to differences between this version and the Version of Record.
Ethics approval and consent to participate Not applicable. Consent for publication Not applicable. Competing interests The authors declare that they have no competing interests. Funding None.
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Please send us corrections, updates, or comments. c19early involves the extraction of 100,000+ datapoints from thousands of papers. Community updates help ensure high accuracy. Treatments and other interventions are complementary. All practical, effective, and safe means should be used based on risk/benefit analysis. No treatment or intervention is 100% available and effective for all current and future variants. We do not provide medical advice. Before taking any medication, consult a qualified physician who can provide personalized advice and details of risks and benefits based on your medical history and situation. FLCCC and WCH provide treatment protocols.
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