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All Studies   Meta Analysis    Recent:   
0 0.5 1 1.5 2+ Mortality -40% unadjusted Improvement Relative Risk Remdesivir for COVID-19  Oku et al.  LATE TREATMENT Is late treatment with remdesivir beneficial for COVID-19? Retrospective 218 patients in Japan (June 2020 - June 2021) Higher mortality with remdesivir (not stat. sig., p=0.59) c19early.org Oku et al., Modern Rheumatology, September 2022 Favors remdesivir Favors control

Risk factors for hospitalization or mortality for COVID-19 in patients with rheumatic diseases: Results of a nation-wide JCR COVID-19 registry in Japan

Oku et al., Modern Rheumatology, doi:10.1093/mr/roac104
Sep 2022  
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Retrospective 220 COVID-19 patients with rheumatic disease in Japan, showing no significant difference in mortality with remdesivir treatment.
Gérard, Wu, Zhou show significantly increased risk of acute kidney injury with remdesivir.
This study is excluded in the after exclusion results of meta analysis: unadjusted results with no group details.
Study covers remdesivir and HCQ.
risk of death, 40.2% higher, RR 1.40, p = 0.59, treatment 3 of 46 (6.5%), control 8 of 172 (4.7%), unadjusted, odds ratio converted to relative risk.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Oku et al., 6 Sep 2022, retrospective, Japan, peer-reviewed, 8 authors, study period 3 June, 2020 - 30 June, 2021. Contact: horiuchi.takahiko.191@m.kyushu-u.ac.jp.
This PaperRemdesivirAll
MORH-D-22-00049 Received: 20-Jan-2022; Accepted: 4-Aug-2022
Kenji Oku, Yasutaka Kimoto, Takahiko Horiuchi, Mari Yamamoto, Yasushi Kondo, Masashi Okamoto, Tatsuya Atsumi, Tsutomu Takeuchi, Y Makino, Matsubara Mayflower, Hospital Misaki
doi:10.1093/mr/roac104/6692611
Background: The incidence and prognosis of COVID-19 and rheumatic disease vary among ethnicities and regions. COVID-19 outcomes in rheumatic disease patients remain unclear, especially in the Asia-Pacific region. This study aimed to clarify the demographic and clinical factors that may influence COVID-19 prognosis in rheumatic disease patients.
Conflict of interest K. Oku, Y. Kimoto, T. Horiuchi, M. Yamamoto, Y. Kondo, M. Okamoto, and Tatsuya Atsumi have no conflicts of interest to declare. T.Takeuchi has received a speaking fee from Eli Lilly Japan K.K., and a research grant from Chugai Pharmaceutical Co.
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Late treatment
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