Alkalinization
Analgesics..
Antiandrogens..
Bromhexine
Budesonide
Cannabidiol
Colchicine
Conv. Plasma
Curcumin
Ensovibep
Famotidine
Favipiravir
Fluvoxamine
Hydroxychlor..
Iota-carragee..
Ivermectin
Lactoferrin
Lifestyle..
Melatonin
Metformin
Molnupiravir
Monoclonals..
Nigella Sativa
Nitazoxanide
Nitric Oxide
Paxlovid
Peg.. Lambda
Povidone-Iod..
Quercetin
Remdesivir
Vitamins..
Zinc

Other
Feedback
Home
Home   COVID-19 treatment studies for Favipiravir  COVID-19 treatment studies for Favipiravir  C19 studies: Favipiravir  Favipiravir   Select treatmentSelect treatmentTreatmentsTreatments
Alkalinization Meta Lactoferrin Meta
Melatonin Meta
Bromhexine Meta Metformin Meta
Budesonide Meta Molnupiravir Meta
Cannabidiol Meta
Colchicine Meta Nigella Sativa Meta
Conv. Plasma Meta Nitazoxanide Meta
Curcumin Meta Nitric Oxide Meta
Ensovibep Meta Paxlovid Meta
Famotidine Meta Peg.. Lambda Meta
Favipiravir Meta Povidone-Iod.. Meta
Fluvoxamine Meta Quercetin Meta
Hydroxychlor.. Meta Remdesivir Meta
Iota-carragee.. Meta
Ivermectin Meta Zinc Meta

Other Treatments Global Adoption
All Studies   Meta Analysis   Recent:  
0 0.5 1 1.5 2+ Mortality 85% Improvement Relative Risk c19early.org/a Yulia et al. Favipiravir for COVID-19 LATE TREATMENT Is late treatment with favipiravir beneficial for COVID-19? Retrospective 432 patients in Indonesia (July - December 2020) Lower mortality with favipiravir (not stat. sig., p=0.052) Yulia et al., Pathophysiology, doi:10.3390/pathophysiology29010009 Favors favipiravir Favors control
Evaluation of Antibacterial and Antiviral Drug Effectiveness in COVID-19 Therapy: A Data-Driven Retrospective Approach
Yulia et al., Pathophysiology, doi:10.3390/pathophysiology29010009
Yulia et al., Evaluation of Antibacterial and Antiviral Drug Effectiveness in COVID-19 Therapy: A Data-Driven Retrospective.., Pathophysiology, doi:10.3390/pathophysiology29010009
Mar 2022   Source   PDF  
  Twitter
  Facebook
Share
  All Studies   Meta
Retrospective hospitalized patients in Indonesia, showing lower mortality and shorter hospitalization with favipiravir.
risk of death, 85.3% lower, OR 0.15, p = 0.05, inverted to make OR<1 favor treatment, RR approximated with OR.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Yulia et al., 7 Mar 2022, retrospective, Indonesia, peer-reviewed, median age 46.0, 10 authors, study period July 2020 - December 2020.
Contact: fauna@staff.ubaya.ac.id (corresponding author), rika_y@staff.ubaya.ac.id, putriayuirma@gmail.com, rudd_apt@yahoo.com, purisafitrihanum@staff.ubaya.ac.id, herwyno@staff.ubaya.ac.id, lestionoapt@gmail.com, deramdani123@gmail.com, abusuquf@yahoo.co.id, kevin.kantono@aut.ac.nz.
All Studies   Meta Analysis   Submit Updates or Corrections
This PaperFavipiravirAll
Abstract: Article Evaluation of Antibacterial and Antiviral Drug Effectiveness in COVID-19 Therapy: A Data-Driven Retrospective Approach Rika Yulia 1 , Putri Ayu Irma Ikasanti 1 , Fauna Herawati 1,2, * , Ruddy Hartono 3 , Puri Safitri Hanum 4 , Lestiono 5 , Dewi Ramdani 6 , Abdul Kadir Jaelani 7 , Kevin Kantono 8 and Heru Wijono 4 1 2 3 4 5 6 7 8 *   Citation: Yulia, R.; Ikasanti, P.A.I.; Herawati, F.; Hartono, R.; Hanum, P.S.; Lestiono; Ramdani, D.; Jaelani, A.K.; Kantono, K.; Wijono, H. Evaluation of Antibacterial and Antiviral Drug Effectiveness in COVID-19 Therapy: A Data-Driven Retrospective Approach. Pathophysiology 2022, 29, 92–105. https://doi.org/10.3390/ pathophysiology29010009 Academic Editor: Jonathan Steven Alexander Received: 9 December 2021 Accepted: 3 March 2022 Published: 7 March 2022 Publisher’s Note: MDPI stays neutral with regard to jurisdictional claims in published maps and institutional affiliations. Department of Clinical and Community Pharmacy, Faculty of Pharmacy, Universitas Surabaya, Surabaya 60293, Indonesia; rika_y@staff.ubaya.ac.id (R.Y.); putriayuirma@gmail.com (P.A.I.I.) Department of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, Universitas Indonesia, Depok 16424, Indonesia Department of Pharmacy, Rumah Sakit Bhayangkara, Surabaya 60231, Indonesia; rudd_apt@yahoo.com Faculty of Medicine, Universitas Surabaya, Surabaya 60293, Indonesia; purisafitrihanum@staff.ubaya.ac.id (P.S.H.); herwyno@staff.ubaya.ac.id (H.W.) Department of Pharmacy, Rumah Sakit Pusat TNI Angkatan Laut (RSPAL) Dr. Ramelan, Surabaya 60244, Indonesia; lestionoapt@gmail.com Department of Pharmacy, Rumah Sakit Umum Haji, Surabaya 60177, Indonesia; deramdani123@gmail.com Department of Pharmacy, RSUD Bangil, Pasuruan 67153, Indonesia; abusuquf@yahoo.co.id Department of Food Science, Auckland University of Technology, Private Bag 92006, Auckland 1142, New Zealand; kevin.kantono@aut.ac.nz Correspondence: fauna@staff.ubaya.ac.id Abstract: The clinical manifestations associated with COVID-19 disease is mainly due to a dysregulated host response related to the overexpression of inflammatory markers. Until recently, only remdesivir had gained FDA approval for COVID-19 hospitalized patients and there are currently no evidence-based therapeutic options or options for prevention of complications that have been established. Some medical treatments such as antivirals, antibacterials, antithrombotics, antipyretics, corticosteroids, interleukin inhibitors, monoclonal antibodies, convalescent plasma, immunostimulants, and vitamin supplements have been utilized. However, there are limited data to support their effectiveness. Hence, this study was attempted to identify and evaluate the effectiveness of antibacterials and antivirals used for COVID-19 using a retrospective cross-sectional approach based on the medical records of adult patients in four hospitals. The number of antibacterials was calculated in defined daily dose (DDD) per 100 bed-days unit. Both mixed-logit regression and analysis of covariance were used to determine the effectiveness of the aforementioned agents in relation to COVID-19 outcome and patients’ length of stay. The model was weighed accordingly and covariates (e.g., age) were considered in the model. Heart disease was found to be the most common pre-existing condition of COVID-19 hospitalized patients in this study. Azithromycin, an antibacterial in the Watch category list, was used extensively (33–65 DDD..
Late treatment
is less effective
Please send us corrections, updates, or comments. Vaccines and treatments are complementary. All practical, effective, and safe means should be used based on risk/benefit analysis. No treatment, vaccine, or intervention is 100% available and effective for all current and future variants. We do not provide medical advice. Before taking any medication, consult a qualified physician who can provide personalized advice and details of risks and benefits based on your medical history and situation. FLCCC and WCH provide treatment protocols.
  or use drag and drop   
Submit