In vivo evaluation of Andrographis paniculata and Boesenbergia rotunda extract activity against SARS-CoV-2 Delta variant in Golden Syrian hamsters: Potential herbal alternative for COVID-19 treatment

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(fingerroot)", "author": "Isa", "doi-asserted-by": "crossref", "first-page": "524", "issue": "6", "journal-title": "Braz J Med Biol Res", "key": "10.1016/j.jtcme.2024.05.004_bib20", "volume": "45", "year": "2012" }, { "DOI": "10.2147/JEP.S382895", "article-title": "Pharmacological activities of fingerroot extract and its phytoconstituents against SARS-CoV-2 infection in golden Syrian hamsters", "author": "Kongratanapasert", "doi-asserted-by": "crossref", "first-page": "13", "journal-title": "J Exp Pharmacol", "key": "10.1016/j.jtcme.2024.05.004_bib21", "volume": "15", "year": "2023" }, { "DOI": "10.1155/2014/274905", "article-title": "Wall. ex Nees: a review of ethnobotany, phytochemistry, and pharmacology", "author": "Hossain", "doi-asserted-by": "crossref", "journal-title": "Sci World J", "key": "10.1016/j.jtcme.2024.05.004_bib22", "volume": "2014", "year": "2014" }, { "DOI": "10.3390/life11040348", "article-title": "Andrographis paniculata (burm. F.) wall. Ex nees: an updated review of phytochemistry, antimicrobial pharmacology, and clinical safety and efficacy", "author": "Hossain", "doi-asserted-by": "crossref", "first-page": "348", "issue": "4", "journal-title": "Life", "key": "10.1016/j.jtcme.2024.05.004_bib23", "volume": "11", "year": "2021" }, { "DOI": "10.1016/j.micinf.2017.08.009", "article-title": "Andrographolide inhibits influenza A virus-induced inflammation in a murine model through NF-κB and JAK-STAT signaling pathway", "author": "Ding", "doi-asserted-by": "crossref", "first-page": "605", "issue": "12", "journal-title": "Microb Infect", "key": "10.1016/j.jtcme.2024.05.004_bib24", "volume": "19", "year": "2017" }, { "DOI": "10.1155/2013/846740", "article-title": "Experimental and clinical pharmacology of Andrographis paniculata and its major bioactive phytoconstituent andrographolide", "author": "Jayakumar", "doi-asserted-by": "crossref", "journal-title": "Evid Based Complement Alternat Med", "key": "10.1016/j.jtcme.2024.05.004_bib25", "volume": "2013", "year": "2013" }, { "DOI": "10.1074/mcp.M113.029793", "article-title": "A quantitative chemical proteomics approach to profile the specific cellular targets of andrographolide, a promising anticancer agent that suppresses tumor metastasis", "author": "Wang", "doi-asserted-by": "crossref", "first-page": "876", "issue": "3", "journal-title": "Mol Cell Proteomics", "key": "10.1016/j.jtcme.2024.05.004_bib26", "volume": "13", "year": "2014" }, { "DOI": "10.1002/ptr.7324", "article-title": "Andrographolide: a review of its pharmacology, pharmacokinetics, toxicity and clinical trials and pharmaceutical researches", "author": "Zeng", "doi-asserted-by": "crossref", "first-page": "336", "issue": "1", "journal-title": "Phytother Res", "key": "10.1016/j.jtcme.2024.05.004_bib27", "volume": "36", "year": "2022" }, { "DOI": "10.1016/j.bcp.2019.113646", "article-title": "Andrographolide inhibits inflammatory responses in LPS-stimulated macrophages and murine acute colitis through activating AMPK", "author": "Kim", "doi-asserted-by": "crossref", "journal-title": "Biochem Pharmacol", "key": "10.1016/j.jtcme.2024.05.004_bib28", "volume": "170", "year": "2019" }, { "article-title": "Andrographolide inhibits inflammatory cytokines secretion in LPS-stimulated RAW264.7 cells through suppression of NF-κB/MAPK signaling pathway", "author": "Li", "journal-title": "Evid Based Complement Alternat Med", "key": "10.1016/j.jtcme.2024.05.004_bib29", "volume": "2017", "year": "2017" }, { "DOI": "10.1038/s41598-017-04673-x", "article-title": "Attenuation of innate immunity by andrographolide derivatives through NF-κB signaling pathway", "author": "Nie", "doi-asserted-by": "crossref", "first-page": "4738", "issue": "1", "journal-title": "Sci Rep", "key": "10.1016/j.jtcme.2024.05.004_bib30", "volume": "7", "year": "2017" }, { "DOI": "10.1007/s00705-016-3166-3", "article-title": "Broad-spectrum antiviral properties of andrographolide", "author": "Gupta", "doi-asserted-by": "crossref", "first-page": "611", "issue": "3", "journal-title": "Arch Virol", "key": "10.1016/j.jtcme.2024.05.004_bib31", "volume": "162", "year": "2017" }, { "DOI": "10.1016/j.csbj.2022.05.053", "article-title": "Discovery of C-12 dithiocarbamate andrographolide analogues as inhibitors of SARS-CoV-2 main protease: in vitro and in silico studies", "author": "Nutho", "doi-asserted-by": "crossref", "first-page": "2784", "journal-title": "Comput Struct Biotechnol J", "key": "10.1016/j.jtcme.2024.05.004_bib32", "volume": "20", "year": "2022" }, { "DOI": "10.1016/j.bbrc.2020.08.086", "article-title": "Andrographolide and its fluorescent derivative inhibit the main proteases of 2019-nCoV and SARS-CoV through covalent linkage", "author": "Shi", "doi-asserted-by": "crossref", "first-page": "467", "issue": "3", "journal-title": "Biochem Biophys Res Commun", "key": "10.1016/j.jtcme.2024.05.004_bib33", "volume": "533", "year": "2020" }, { "author": "Patcharanaruamol", "key": "10.1016/j.jtcme.2024.05.004_bib34", "series-title": "COVID-19 Health System Response Monitor: Thailand", "year": "2020" }, { "DOI": "10.3389/fmed.2022.947373", "article-title": "Use of Andrographis paniculata (Burm.f.) Wall. ex Nees and risk of pneumonia in hospitalised patients with mild coronavirus disease 2019: a retrospective cohort study", "author": "Tanwettiyanont", "doi-asserted-by": "crossref", "journal-title": "Front Med", "key": "10.1016/j.jtcme.2024.05.004_bib35", "volume": "9", "year": "2022" }, { "key": "10.1016/j.jtcme.2024.05.004_bib36", "series-title": "Statement on the Fifteenth Meeting of the IHR (2005) Emergency Committee on the COVID-19 Pandemic", "year": "2023" }, { "DOI": "10.1186/s13054-021-03662-x", "article-title": "Emerging SARS-CoV-2 variants of concern and potential intervention approaches", "author": "Khateeb", "doi-asserted-by": "crossref", "first-page": "244", "issue": "1", "journal-title": "Crit Care", "key": "10.1016/j.jtcme.2024.05.004_bib37", "volume": "25", "year": "2021" }, { "article-title": "SARS-COV-2 variants: differences and potential of immune evasion", "author": "Hirabara", "journal-title": "Front Cell Infect Microbiol", "key": "10.1016/j.jtcme.2024.05.004_bib38", "volume": "11", "year": "2021" }, { "DOI": "10.1038/s41392-022-00997-x", "article-title": "SARS-CoV-2 Omicron variant: recent progress and future perspectives", "author": "Fan", "doi-asserted-by": "crossref", "first-page": "141", "issue": "1", "journal-title": "Signal Transduct Targeted Ther", "key": "10.1016/j.jtcme.2024.05.004_bib39", "volume": "7", "year": "2022" }, { "DOI": "10.1038/s41588-022-01033-y", "article-title": "Global landscape of SARS-CoV-2 genomic surveillance and data sharing", "author": "Chen", "doi-asserted-by": "crossref", "first-page": "499", "issue": "4", "journal-title": "Nat Genet", "key": "10.1016/j.jtcme.2024.05.004_bib40", "volume": "54", "year": "2022" }, { "DOI": "10.1038/s41577-022-00678-4", "article-title": "Milder disease with Omicron: is it the virus or the pre-existing immunity?", "author": "Sigal", "doi-asserted-by": "crossref", "first-page": "69", "issue": "2", "journal-title": "Nat Rev Immunol", "key": "10.1016/j.jtcme.2024.05.004_bib41", "volume": "22", "year": "2022" }, { "DOI": "10.1016/j.eclinm.2022.101455", "article-title": "Severe hospital events following symptomatic infection with Sars-CoV-2 Omicron and Delta variants in France, December 2021-January 2022: a retrospective, population-based, matched cohort study", "author": "Auvigne", "doi-asserted-by": "crossref", "journal-title": "EClinicalMedicine", "key": "10.1016/j.jtcme.2024.05.004_bib42", "volume": "48", "year": "2022" }, { "DOI": "10.15585/mmwr.mm7137a4", "article-title": "Mortality risk among patients hospitalized primarily for COVID-19 during the omicron and Delta variant pandemic periods - United States, April 2020-June 2022", "author": "Adjei", "doi-asserted-by": "crossref", "first-page": "1182", "issue": "37", "journal-title": "MMWR Morb Mortal Wkly Rep", "key": "10.1016/j.jtcme.2024.05.004_bib43", "volume": "71", "year": "2022" }, { "DOI": "10.1111/irv.12982", "article-title": "COVID-19 severity from Omicron and Delta SARS-CoV-2 variants", "author": "Wrenn", "doi-asserted-by": "crossref", "first-page": "832", "issue": "5", "journal-title": "Influenza Other Respir Viruses", "key": "10.1016/j.jtcme.2024.05.004_bib44", "volume": "16", "year": "2022" }, { "DOI": "10.15252/embj.2021108944", "article-title": "SARS-CoV-2 Alpha, Beta, and Delta variants display enhanced Spike-mediated syncytia formation", "author": "Rajah", "doi-asserted-by": "crossref", "issue": "24", "journal-title": "EMBO J", "key": "10.1016/j.jtcme.2024.05.004_bib45", "volume": "40", "year": "2021" }, { "DOI": "10.1038/s41586-021-04266-9", "article-title": "Enhanced fusogenicity and pathogenicity of SARS-CoV-2 Delta P681R mutation", "author": "Saito", "doi-asserted-by": "crossref", "first-page": "300", "issue": "7896", "journal-title": "Nature", "key": "10.1016/j.jtcme.2024.05.004_bib46", "volume": "602", "year": "2022" }, { "DOI": "10.1038/s41586-021-03491-6", "article-title": "Drugs that inhibit TMEM16 proteins block SARS-CoV-2 spike-induced syncytia", "author": "Braga", "doi-asserted-by": "crossref", "first-page": "88", "issue": "7861", "journal-title": "Nature", "key": "10.1016/j.jtcme.2024.05.004_bib47", "volume": "594", "year": "2021" }, { "DOI": "10.1016/j.ebiom.2020.103104", "article-title": "Persistence of viral RNA, pneumocyte syncytia and thrombosis are hallmarks of advanced COVID-19 pathology", "author": "Bussani", "doi-asserted-by": "crossref", "journal-title": "EBioMedicine", "key": "10.1016/j.jtcme.2024.05.004_bib48", "volume": "61", "year": "2020" }, { "DOI": "10.15252/embj.2020106267", "article-title": "Syncytia formation by SARS-CoV-2-infected cells", "author": "Buchrieser", "doi-asserted-by": "crossref", "issue": "23", "journal-title": "EMBO J", "key": "10.1016/j.jtcme.2024.05.004_bib49", "volume": "39", "year": "2020" }, { "DOI": "10.1016/j.jmb.2021.167280", "article-title": "The mechanism and consequences of SARS-CoV-2 spike-mediated fusion and syncytia formation", "author": "Rajah", "doi-asserted-by": "crossref", "issue": "6", "journal-title": "J Mol Biol", "key": "10.1016/j.jtcme.2024.05.004_bib50", "volume": "434", "year": "2022" }, { "DOI": "10.1080/22221751.2021.2023329", "article-title": "SARS-CoV-2 Omicron variant shows less efficient replication and fusion activity when compared with Delta variant in TMPRSS2-expressed cells", "author": "Zhao", "doi-asserted-by": "crossref", "first-page": "277", "issue": "1", "journal-title": "Emerg Microb Infect", "key": "10.1016/j.jtcme.2024.05.004_bib51", "volume": "11", "year": "2022" }, { "DOI": "10.1038/s41577-022-00681-9", "article-title": "Omicron entry route", "author": "Pia", "doi-asserted-by": "crossref", "first-page": "144", "issue": "3", "journal-title": "Nat Rev Immunol", "key": "10.1016/j.jtcme.2024.05.004_bib52", "volume": "22", "year": "2022" }, { "DOI": "10.1038/s41586-022-04474-x", "article-title": "Altered TMPRSS2 usage by SARS-CoV-2 Omicron impacts infectivity and fusogenicity", "author": "Meng", "doi-asserted-by": "crossref", "first-page": "706", "issue": "7902", "journal-title": "Nature", "key": "10.1016/j.jtcme.2024.05.004_bib53", "volume": "603", "year": "2022" }, { "DOI": "10.1038/s41392-022-00941-z", "article-title": "SARS-CoV-2 spike L452R mutation increases Omicron variant fusogenicity and infectivity as well as host glycolysis", "author": "Zhang", "doi-asserted-by": "crossref", "first-page": "76", "issue": "1", "journal-title": "Signal Transduct Targeted Ther", "key": "10.1016/j.jtcme.2024.05.004_bib54", "volume": "7", "year": "2022" }, { "DOI": "10.1038/s41467-023-38435-3", "article-title": "Virological characteristics of the SARS-CoV-2 XBB variant derived from recombination of two Omicron subvariants", "author": "Tamura", "doi-asserted-by": "crossref", "first-page": "2800", "issue": "1", "journal-title": "Nat Commun", "key": "10.1016/j.jtcme.2024.05.004_bib55", "volume": "14", "year": "2023" }, { "DOI": "10.3389/fimmu.2020.01446", "article-title": "The COVID-19 cytokine storm; what we know so far", "author": "Ragab", "doi-asserted-by": "crossref", "first-page": "1446", "journal-title": "Front Immunol", "key": "10.1016/j.jtcme.2024.05.004_bib56", "volume": "11", "year": "2020" }, { "DOI": "10.3389/fimmu.2020.558898", "article-title": "COVID-19: in the eye of the cytokine storm", "author": "de la Rica", "doi-asserted-by": "crossref", "journal-title": "Front Immunol", "key": "10.1016/j.jtcme.2024.05.004_bib57", "volume": "11", "year": "2020" }, { "DOI": "10.1056/NEJMra2026131", "article-title": "Cytokine storm", "author": "Fajgenbaum", "doi-asserted-by": "crossref", "first-page": "2255", "issue": "23", "journal-title": "N Engl J Med", "key": "10.1016/j.jtcme.2024.05.004_bib58", "volume": "383", "year": "2020" }, { "DOI": "10.1016/j.ijid.2021.09.021", "article-title": "SARS-CoV-2 neutralizing antibodies decline over one year and patients with severe COVID-19 pneumonia display a unique cytokine profile", "author": "Vacharathit", "doi-asserted-by": "crossref", "first-page": "227", "journal-title": "Int J Infect Dis", "key": "10.1016/j.jtcme.2024.05.004_bib59", "volume": "112", "year": "2021" }, { "DOI": "10.15252/emmm.202012421", "article-title": "The role of interleukin-6 in monitoring severe case of coronavirus disease 2019", "author": "Liu", "doi-asserted-by": "crossref", "issue": "7", "journal-title": "EMBO Mol Med", "key": "10.1016/j.jtcme.2024.05.004_bib60", "volume": "12", "year": "2020" }, { "DOI": "10.1038/s41392-021-00653-w", "article-title": "Molecular mechanism of interaction between SARS-CoV-2 and host cells and interventional therapy", "author": "Zhang", "doi-asserted-by": "crossref", "first-page": "233", "issue": "1", "journal-title": "Signal Transduct Targeted Ther", "key": "10.1016/j.jtcme.2024.05.004_bib61", "volume": "6", "year": "2021" }, { "DOI": "10.1073/pnas.2204624119", "article-title": "A single-administration therapeutic interfering particle reduces SARS-CoV-2 viral shedding and pathogenesis in hamsters", "author": "Chaturvedi", "doi-asserted-by": "crossref", "issue": "39", "journal-title": "Proc Natl Acad Sci U S A", "key": "10.1016/j.jtcme.2024.05.004_bib62", "volume": "119", "year": "2022" }, { "DOI": "10.1038/s41586-020-2342-5", "article-title": "Pathogenesis and transmission of SARS-CoV-2 in golden hamsters", "author": "Sia", "doi-asserted-by": "crossref", "first-page": "834", "issue": "7818", "journal-title": "Nature", "key": "10.1016/j.jtcme.2024.05.004_bib63", "volume": "583", "year": "2020" }, { "DOI": "10.1038/s41467-020-19684-y", "article-title": "STAT2 signaling restricts viral dissemination but drives severe pneumonia in SARS-CoV-2 infected hamsters", "author": "Boudewijns", "doi-asserted-by": "crossref", "first-page": "5838", "issue": "1", "journal-title": "Nat Commun", "key": "10.1016/j.jtcme.2024.05.004_bib64", "volume": "11", "year": "2020" }, { "DOI": "10.1165/rcmb.2009-0210ST", "article-title": "An official American Thoracic Society workshop report: features and measurements of experimental acute lung injury in animals", "author": "Matute-Bello", "doi-asserted-by": "crossref", "first-page": "725", "issue": "5", "journal-title": "Am J Respir Cell Mol Biol", "key": "10.1016/j.jtcme.2024.05.004_bib65", "volume": "44", "year": "2011" }, { "DOI": "10.1016/j.virs.2022.09.008", "article-title": "Increased pathogenicity and aerosol transmission for one SARS-CoV-2 B.1.617.2 Delta variant over the wild-type strain in hamsters", "author": "Zhang", "doi-asserted-by": "crossref", "first-page": "796", "issue": "6", "journal-title": "Virol Sin", "key": "10.1016/j.jtcme.2024.05.004_bib66", "volume": "37", "year": "2022" }, { "DOI": "10.3390/v13091773", "article-title": "SARS-CoV-2 Delta variant pathogenesis and host response in Syrian hamsters", "author": "Mohandas", "doi-asserted-by": "crossref", "first-page": "1773", "issue": "9", "journal-title": "Viruses", "key": "10.1016/j.jtcme.2024.05.004_bib67", "volume": "13", "year": "2021" }, { "DOI": "10.1186/cc342", "article-title": "The measurement of lung water", "author": "Lange", "doi-asserted-by": "crossref", "first-page": "R19", "issue": "2", "journal-title": "Crit Care", "key": "10.1016/j.jtcme.2024.05.004_bib68", "volume": "3", "year": "1999" }, { "DOI": "10.3389/fpubh.2022.873596", "article-title": "The effectiveness of COVID-19 vaccines in reducing the incidence, hospitalization, and mortality from COVID-19: a systematic review and meta-analysis", "author": "Rahmani", "doi-asserted-by": "crossref", "journal-title": "Front Public Health", "key": "10.1016/j.jtcme.2024.05.004_bib69", "volume": "10", "year": "2022" }, { "DOI": "10.1038/s41577-021-00662-4", "article-title": "SARS-CoV-2 breakthrough infections in vaccinated individuals: measurement, causes and impact", "author": "Lipsitch", "doi-asserted-by": "crossref", "first-page": "57", "issue": "1", "journal-title": "Nat Rev Immunol", "key": "10.1016/j.jtcme.2024.05.004_bib70", "volume": "22", "year": "2022" }, { "DOI": "10.1016/j.jtcme.2020.05.003", "article-title": "The antiviral and coronavirus-host protein pathways inhibiting properties of herbs and natural compounds - additional weapons in the fight against the COVID-19 pandemic?", "author": "Fuzimoto", "doi-asserted-by": "crossref", "first-page": "405", "issue": "4", "journal-title": "J Tradit Complement Med", "key": "10.1016/j.jtcme.2024.05.004_bib71", "volume": "10", "year": "2020" }, { "DOI": "10.1016/j.metop.2021.100141", "article-title": "Herbal medicine use for the management of COVID-19: a review article", "author": "Demeke", "doi-asserted-by": "crossref", "journal-title": "Metabol Open", "key": "10.1016/j.jtcme.2024.05.004_bib72", "volume": "12", "year": "2021" }, { "DOI": "10.1080/21655979.2022.2036521", "article-title": "Prevention, treatment and potential mechanism of herbal medicine for Corona viruses: a review", "author": "Liu", "doi-asserted-by": "crossref", "first-page": "5480", "issue": "3", "journal-title": "Bioengineered", "key": "10.1016/j.jtcme.2024.05.004_bib73", "volume": "13", "year": "2022" }, { "DOI": "10.1016/j.biopha.2023.115682", "article-title": "Antiviral, virucidal and antioxidant properties of Artemisia annua against SARS-CoV-2", "author": "Baggieri", "doi-asserted-by": "crossref", "journal-title": "Biomed Pharmacother", "key": "10.1016/j.jtcme.2024.05.004_bib74", "volume": "168", "year": "2023" }, { "DOI": "10.4103/2221-1691.319567", "article-title": "Anti-viral and anti-inflammatory effects of kaempferol and quercetin and COVID-2019: a scoping review", "author": "Khazdair", "doi-asserted-by": "crossref", "first-page": "327", "issue": "8", "journal-title": "Asian Pac J Trop Biomed", "key": "10.1016/j.jtcme.2024.05.004_bib75", "volume": "11", "year": "2021" }, { "DOI": "10.1080/07391102.2020.1868338", "article-title": "Virtual screening of curcumin and its analogs against the spike surface glycoprotein of SARS-CoV-2 and SARS-CoV", "author": "Patel", "doi-asserted-by": "crossref", "first-page": "5138", "issue": "11", "journal-title": "J Biomol Struct Dyn", "key": "10.1016/j.jtcme.2024.05.004_bib76", "volume": "40", "year": "2022" }, { "DOI": "10.3390/nu14020256", "article-title": "Effectiveness of curcumin on outcomes of hospitalized COVID-19 patients: a systematic review of clinical trials", "author": "Vahedian-Azimi", "doi-asserted-by": "crossref", "first-page": "256", "issue": "2", "journal-title": "Nutrients", "key": "10.1016/j.jtcme.2024.05.004_bib77", "volume": "14", "year": "2022" }, { "DOI": "10.3390/v16030320", "article-title": "Treating COVID-19 with medicinal plants: is it even conceivable? A comprehensive review", "author": "Al-Jamal", "doi-asserted-by": "crossref", "first-page": "320", "issue": "3", "journal-title": "Viruses", "key": "10.1016/j.jtcme.2024.05.004_bib78", "volume": "16", "year": "2024" }, { "DOI": "10.1111/bcp.14543", "article-title": "Approaching sites of action of drugs in clinical pharmacology: new analytical options and their challenges", "author": "Longuespée", "doi-asserted-by": "crossref", "first-page": "858", "issue": "3", "journal-title": "Br J Clin Pharmacol", "key": "10.1016/j.jtcme.2024.05.004_bib79", "volume": "87", "year": "2021" }, { "DOI": "10.29290/PDDA.1.5.2019.2-13", "article-title": "Review on the various drug delivery systems of andrographolide", "author": "Malarvizhi", "doi-asserted-by": "crossref", "first-page": "2", "journal-title": "Phytopharm. Drug Deliv. Approaches", "key": "10.1016/j.jtcme.2024.05.004_bib80", "year": "2019" }, { "DOI": "10.1016/j.eng.2018.12.004", "article-title": "Andrographolide loaded in micro-and nano-formulations: improved bioavailability, target-tissue distribution, and efficacy of the “king of bitters”", "author": "Casamonti", "doi-asserted-by": "crossref", "first-page": "69", "issue": "1", "journal-title": "Engineering", "key": "10.1016/j.jtcme.2024.05.004_bib81", "volume": "5", "year": "2019" }, { "DOI": "10.1080/13880209.2024.2311201", "article-title": "Enhancing oral bioavailability of andrographolide using solubilizing agents and bioenhancer: comparative pharmacokinetics of Andrographis paniculata formulations in beagle dogs", "author": "Songvut", "doi-asserted-by": "crossref", "first-page": "183", "issue": "1", "journal-title": "Pharm Biol", "key": "10.1016/j.jtcme.2024.05.004_bib82", "volume": "62", "year": "2024" }, { "DOI": "10.3390/molecules26010005", "article-title": "Andrographolide, an anti-inflammatory multitarget drug: all roads lead to cellular metabolism", "author": "Burgos", "doi-asserted-by": "crossref", "issue": "1", "journal-title": "Molecules", "key": "10.1016/j.jtcme.2024.05.004_bib83", "volume": "26", "year": "2020" }, { "DOI": "10.1177/1947601910383416", "article-title": "Andrographolide, an herbal medicine, inhibits interleukin-6 expression and suppresses prostate cancer cell growth", "author": "Chun", "doi-asserted-by": "crossref", "first-page": "868", "issue": "8", "journal-title": "Genes Cancer", "key": "10.1016/j.jtcme.2024.05.004_bib84", "volume": "1", "year": "2010" }, { "DOI": "10.1007/s10753-014-9902-5", "article-title": "Andrographolide suppresses IL-6/Stat3 signaling in peripheral blood mononuclear cells from patients with chronic rhinosinusitis with nasal polyps", "author": "Kou", "doi-asserted-by": "crossref", "first-page": "1738", "issue": "5", "journal-title": "Inflammation", "key": "10.1016/j.jtcme.2024.05.004_bib85", "volume": "37", "year": "2014" }, { "article-title": "Andrographolide, a natural anti-inflammatory agent: an Update", "author": "Li", "journal-title": "Front Pharmacol", "key": "10.1016/j.jtcme.2024.05.004_bib86", "volume": "13", "year": "2022" }, { "DOI": "10.1111/bph.12054", "article-title": "Andrographolide protects against cigarette smoke-induced oxidative lung injury via augmentation of Nrf2 activity", "author": "Guan", "doi-asserted-by": "crossref", "first-page": "1707", "issue": "7", "journal-title": "Br J Pharmacol", "key": "10.1016/j.jtcme.2024.05.004_bib87", "volume": "168", "year": "2013" }, { "DOI": "10.1002/JLB.3MA1119-584RRR", "article-title": "Andrographolide exerts anti-inflammatory effects in Mycobacterium tuberculosis-infected macrophages by regulating the Notch1/Akt/NF-κB axis", "author": "He", "doi-asserted-by": "crossref", "first-page": "1747", "issue": "6", "journal-title": "J Leukoc Biol", "key": "10.1016/j.jtcme.2024.05.004_bib88", "volume": "108", "year": "2020" }, { "DOI": "10.1186/s12974-016-0498-6", "article-title": "Andrographolide attenuates LPS-stimulated up-regulation of C-C and C-X-C motif chemokines in rodent cortex and primary astrocytes", "author": "Wong", "doi-asserted-by": "crossref", "first-page": "34", "journal-title": "J Neuroinflammation", "key": "10.1016/j.jtcme.2024.05.004_bib89", "volume": "13", "year": "2016" }, { "DOI": "10.1016/j.isci.2022.104759", "article-title": "SARS-CoV-2 Delta spike protein enhances the viral fusogenicity and inflammatory cytokine production", "author": "Ao", "doi-asserted-by": "crossref", "issue": "8", "journal-title": "iScience", "key": "10.1016/j.jtcme.2024.05.004_bib90", "volume": "25", "year": "2022" }, { "DOI": "10.1016/j.cell.2020.10.039", "article-title": "β-Coronaviruses use lysosomes for egress instead of the biosynthetic secretory pathway", "author": "Ghosh", "doi-asserted-by": "crossref", "first-page": "1520", "issue": "6", "journal-title": "Cell", "key": "10.1016/j.jtcme.2024.05.004_bib91", "volume": "183", "year": "2020" }, { "DOI": "10.1039/D0RA10529E", "article-title": "Combination of system biology to probe the anti-viral activity of andrographolide and its derivative against COVID-19", "author": "Khanal", "doi-asserted-by": "crossref", "first-page": "5065", "issue": "9", "journal-title": "RSC Adv", "key": "10.1016/j.jtcme.2024.05.004_bib92", "volume": "11", "year": "2021" }, { "DOI": "10.1016/j.jtcme.2021.10.003", "article-title": "Targeting autophagy with natural products to prevent SARS-CoV-2 infection", "author": "Vidoni", "doi-asserted-by": "crossref", "first-page": "55", "issue": "1", "journal-title": "J Tradit Complement Med", "key": "10.1016/j.jtcme.2024.05.004_bib93", "volume": "12", "year": "2022" } ], "reference-count": 93, "references-count": 93, "relation": {}, "resource": { "primary": { "URL": "https://linkinghub.elsevier.com/retrieve/pii/S2225411024000609" } }, "score": 1, "short-title": [], "source": "Crossref", "subject": [], "subtitle": [], "title": "In vivo evaluation of Andrographis paniculata and Boesenbergia rotunda extract activity against SARS-CoV-2 Delta variant in Golden Syrian hamsters: Potential herbal alternative for COVID-19 treatment", "type": "journal-article", "update-policy": "http://dx.doi.org/10.1016/elsevier_cm_policy", "volume": "14" }