The potential application of probiotics and prebiotics for the prevention and treatment of COVID-19
Olaimat et al.
, The potential application of probiotics and prebiotics for the prevention and treatment of COVID-19
, npj Science of Food, doi:10.1038/s41538-020-00078-9 (Review)
Review of the immune benefits of probiotics and clinical studies for the preventation and treatment of respiratory infections, recommending trials of probiotics for COVID-19.
Olaimat et al., 5 Oct 2020, peer-reviewed, 10 authors.
The potential application of probiotics and prebiotics for the
prevention and treatment of COVID-19
Amin N. Olaimat 1 ✉, Iman Aolymat2, Murad Al-Holy1, Mutamed Ayyash 3 ✉, Mahmoud Abu Ghoush
Tareq Osaili4,5, Vasso Apostolopoulos6, Shao-Quan Liu7 and Nagendra P. Shah8
, Anas A. Al-Nabulsi4,
COVID-19 is a pandemic disease caused by the novel coronavirus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
This new viral infection was ﬁrst identiﬁed in China in December 2019, and it has subsequently spread globally. The lack of a
vaccine or curative treatment for COVID-19 necessitates a focus on other strategies to prevent and treat the infection. Probiotics
consist of single or mixed cultures of live microorganisms that can beneﬁcially affect the host by maintaining the intestinal or lung
microbiota that play a major role in human health. At present, good scientiﬁc evidence exists to support the ability of probiotics to
boost human immunity, thereby preventing colonization by pathogens and reducing the incidence and severity of infections.
Herein, we present clinical studies of the use of probiotic supplementation to prevent or treat respiratory tract infections. These
data lead to promising beneﬁts of probiotics in reducing the risk of COVID-19. Further studies should be conducted to assess the
ability of probiotics to combat COVID-19.
npj Science of Food (2020)4:17 ; https://doi.org/10.1038/s41538-020-00078-9
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