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Probiotics in Prevention and Treatment of COVID-19: Current Perspective and Future Prospects

Kurian et al., Archives of Medical Research, doi:10.1016/j.arcmed.2021.03.002
Mar 2021  
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Probiotics for COVID-19
17th treatment shown to reduce risk in March 2021
 
*, now known with p = 0.0000013 from 26 studies.
No treatment is 100% effective. Protocols combine complementary and synergistic treatments. * >10% efficacy in meta analysis with ≥3 clinical studies.
4,100+ studies for 60+ treatments. c19early.org
Review of probiotics role in regulating the immune system and use in viral infections, and studies on the association of microbiota with COVID-19 patients. Authors suggest that probiotics supplementation could reduce COVID-19 morbidity and mortality, and they note that probiotics may suppress the inflammatory cytokine response.
Reviews covering probiotics for COVID-19 include Baud, Di Pierro, Kurian, Olaimat, Petrariu, Righi, Singh, Stavropoulou, Taufer, Taufer (B).
Kurian et al., 19 Mar 2021, peer-reviewed, 11 authors.
This PaperProbioticsAll
Probiotics in Prevention and Treatment of COVID-19: Current Perspective and Future Prospects
Shilia Jacob Kurian, Mazhuvancherry Kesavan Unnikrishnan, Sonal Sekhar Miraj, Debasis Bagchi, Mithu Banerjee, B Shrikar Reddy, Gabriel Sunil Rodrigues, Mohan K Manu, Kavitha Saravu, Chiranjay Mukhopadhyay, Mahadev Rao
Archives of Medical Research, doi:10.1016/j.arcmed.2021.03.002
Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre -including this research content -immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
Source of Financial Support None Competing Interests The authors report no conflicts of interest Authors' Contribution Dr.Shilia Jacob Kurian and Dr.Sonal Sekhar Miraj conducted the literature search and wrote the manuscript. Dr. B Shrikar Reddy drew the figure I. Dr. Mazhuvancheny Kesavan Unnikrishnan, Dr. Debasis Bagchi, Dr. Mithu Banerjce. Dr. Gabriel Sunil Rodrigues, Dr. Mohan K Manu, Dr. Kavitha Saravu, Dr. Chiranjay Mukhopadhyay and Dr. Mahadev Rao critically evaluated the manuscript. All the authors participated in literature collection and review. All the authors approved the final draft of the manuscript. Supplementary Materials Supplementary material associated with this article can be found, in the online version, at doi: 10.1016/j.arcmed.2021. 03.002.
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