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The In Vitro Virucidal Effects of Mouthwashes on SARS-CoV-2

Ting et al., International Journal of Translational Medicine, doi:10.3390/ijtm2030030
Jul 2022  
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Review of In Vitro studies of mouthwashes, showing antiviral activity for SARS-CoV-2 with many compounds including PVP-I, cetylpyridinium chloride, chlorohexidine gluconate, dequalinium chloride, benzalkonium chloride, and anionic phthalocyanine derivative.
This study includes povidone-iodine, cetylpyridinium chloride, chlorhexidine, and hydrogen peroxide.
Ting et al., 31 Jul 2022, peer-reviewed, 2 authors.
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The In Vitro Virucidal Effects of Mouthwashes on SARS-CoV-2
Miriam Ting, Jon B Suzuki
International Journal of Translational Medicine, doi:10.3390/ijtm2030030
Oral antiseptic mouthwashes have been widely used for their antibacterial activity. As a result of the SARS-CoV-2 pandemic, the antiviral properties of these oral antiseptics have been aggressively studied. To demonstrate the direct antiviral activity of mouthwashes against SARS-CoV-2, this review will focus on the in vitro virucidal effects of these mouthwashes. Knowledge of the type, concentration, and exposure time of available mouthwashes can provide insights into effective protocols for their clinical use. With an understanding of the characteristics of each oral antiseptic mouthwash, proper mouthwash selection against SARS-CoV-2 may become a useful adjunct to personal protective equipment.
Author Contributions: M.T. participated in the design of the review, literature search and article selection, drafting and revising of manuscript and table, and final approval of submitted version. J.B.S. participated in the design of the review, article selection, drafting and revising of manuscript and table, and final approval of submitted version. All authors have read and agreed to the published version of the manuscript. Conflicts of Interest: The authors declare no conflict of interest in the writing of this manuscript. J.B.S. is a U.S. Government Special Government Employee with the US Food and Drug Administration, Silver Spring, MD, USA.
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