Clinical and treatment factors associated with the mortality of COVID-19 patients admitted to a referral hospital in Indonesia
Hartantri et al.,
Clinical and treatment factors associated with the mortality of COVID-19 patients admitted to a referral..,
The Lancet Regional Health - Southeast Asia, doi:10.1016/j.lansea.2023.100167
Retrospective 689 hospitalized patients in Indonesia, showing lower mortality with favipiravir treatment.
risk of death, 76.0% lower, HR 0.24, p < 0.001, adjusted per study, mild/moderate, multivariable, Cox proportional hazards.
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risk of death, 60.0% lower, HR 0.40, p = 0.04, adjusted per study, severe, multivariable, Cox proportional hazards.
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Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
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Hartantri et al., 9 Feb 2023, retrospective, Indonesia, peer-reviewed, 10 authors, study period 1 March, 2020 - 31 December, 2020.
Contact:
b.alisjahbana@unpad.ac.id.
Abstract: Journal Pre-proof
Clinical and treatment factors associated with the mortality of COVID-19 patients
admitted to a referral hospital in Indonesia
Yovita Hartantri, Josephine Debora, Leonardus Widyatmoko, Gezy Giwangkancana,
Hendarsyah Suryadinata, Evan Susandi, Elisabeth Hutajulu, Assica Permata Amalya
Hakiman, Yesy Pusparini, Bachti Alisjahbana
PII:
S2772-3682(23)00027-6
DOI:
https://doi.org/10.1016/j.lansea.2023.100167
Reference:
LANSEA 100167
To appear in:
The Lancet Regional Health - Southeast Asia
Received Date: 19 May 2022
Revised Date:
31 January 2023
Accepted Date: 1 February 2023
Please cite this article as: Hartantri Y, Debora J, Widyatmoko L, Giwangkancana G, Suryadinata H,
Susandi E, Hutajulu E, Amalya Hakiman AP, Pusparini Y, Alisjahbana B, Clinical and treatment factors
associated with the mortality of COVID-19 patients admitted to a referral hospital in Indonesia, The
Lancet Regional Health - Southeast Asia (2023), doi: https://doi.org/10.1016/j.lansea.2023.100167.
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© 2023 The Author(s). Published by Elsevier Ltd.
Clinical and treatment factors associated with the mortality of COVID-19
patients admitted to a referral hospital in Indonesia
Yovita Hartantri1,
Josephine Debora1,
Leonardus Widyatmoko2,
Gezy Giwangkancana3,
Hendarsyah Suryadinata1,
of
Evan Susandi1,
ro
Elisabeth Hutajulu1,
-p
Assica Permata Amalya Hakiman4,
Yesy Pusparini5,
lP
re
Bachti Alisjahbana1,4
1Internal
Medicine Department, Hasan Sadikin General Hospital, Faculty of Medicine,
Pathology Department, Hasan Sadikin General Hospital, Faculty of Medicine,
ur
2Clinical
na
Universitas Padjadjaran, Bandung, Indonesia
Universitas Padjadjaran, Bandung, Indonesia
Jo
3Anesthesiology and Intensive Care Department, Hasan Sadikin General Hospital, Faculty of
Medicine, Universitas Padjadjaran, Bandung, Indonesia
4Research
Center for Care and Control of Infectious Diseases (RC3ID), Universitas
Padjadjaran, Bandung, Indonesia
5Hasan Sadikin General Hospital, Bandung, Indonesia
Corresponding author: Bachti Alisjahbana
Address: Internal Medicine Department, Hasan Sadikin General Hospital, Faculty of
Medicine, Universitas Padjadjaran, Bandung, Indonesia. Jl. Pasteur No. 38, Bandung 40161,
West Java, Indonesia. Email: b.alisjahbana@unpad.ac.id
1
Summary
Background
Indonesia had the second-highest number of COVID-19 cases and deaths in South-East Asia.
We aimed to determine the factors associated with this mortality and the effect of the
recommended COVID-19 treatment regimen during the first 10 months of the epidemic.
Methods
This was a retrospective cohort study using secondary data from medical records. In total,
689 adult COVID-19 inpatients hospitalized between March and December 2020 were
of
enrolled. Clinical characteristics, laboratory parameters, and treatments were analyzed by
ro
survival outcome. Kaplan-Meier statistics were used to estimate..
Late treatment
is less effective
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