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c19early.org COVID-19 treatment researchBamlanivimab/etesevimabBamlaniv../e.. (more..)
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All Studies   Meta Analysis    Recent:   
0 0.5 1 1.5 2+ Hospitalization 51% Improvement Relative Risk Bamlanivimab/e..  Wilden et al.  EARLY TREATMENT Is early treatment with bamlanivimab/etesevimab beneficial for COVID-19? Retrospective study in the USA (December 2020 - July 2021) Lower hospitalization with bamlanivimab/etesevimab (not stat. sig., p=0.06) c19early.org Wilden et al., J. the National Compreh.., Mar 2022 Favors bamlanivimab/e.. Favors control

Real World Outcomes of Cancer Patients With SARS-CoV-2 Infection Receiving Monoclonal Antibodies

Wilden et al., Journal of the National Comprehensive Cancer Network, doi:10.6004/jnccn.2021.7309
Mar 2022  
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22nd treatment shown to reduce risk in May 2021
 
*, now known with p = 0.00039 from 19 studies, recognized in 4 countries. Efficacy is variant dependent.
No treatment is 100% effective. Protocols combine complementary and synergistic treatments. * >10% efficacy in meta analysis with ≥3 clinical studies.
4,000+ studies for 60+ treatments. c19early.org
Retrospective 395 patients in the USA receiving casirivimab/imdevimab or bamlanivimab, showing lower risk of hospitalization with treatment, statistically significant for casirivimab/imdevimab.
Efficacy is highly variant dependent. In Vitro research suggests a lack of efficacy for omicron Haars, Liu, Pochtovyi, Sheward, VanBlargan.
Study covers bamlanivimab/etesevimab and casirivimab/imdevimab.
risk of hospitalization, 51.0% lower, OR 0.49, p = 0.06, adjusted per study, multivariable, RR approximated with OR.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Wilden et al., 31 Mar 2022, retrospective, USA, peer-reviewed, 9 authors, study period December 2020 - July 2021.
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