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Home   COVID-19 treatment studies for Vitamin D  COVID-19 treatment studies for Vitamin D  C19 studies: Vitamin D  Vitamin D   Select treatmentSelect treatmentTreatmentsTreatments
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0 0.5 1 1.5 2+ Mortality -1% Improvement Relative Risk Mortality (b) 4% Case 1% Case (b) 5% c19early.org/d Oristrell et al. Vitamin D for COVID-19 Prophylaxis Is prophylaxis with vitamin D beneficial for COVID-19? Retrospective 404,109 patients in Spain No significant difference in outcomes seen Oristrell et al., J. Endocrinological Investigat.., doi:10.1007/s40618-021-01639-9 Favors vitamin D Favors control
Vitamin D supplementation and COVID-19 risk: a population-based, cohort study
Oristrell et al., Journal of Endocrinological Investigation, doi:10.1007/s40618-021-01639-9
Oristrell et al., Vitamin D supplementation and COVID-19 risk: a population-based, cohort study, Journal of Endocrinological Investigation, doi:10.1007/s40618-021-01639-9
Jul 2021   Source   PDF  
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Retrospective study of cholecalciferol and calcitriol supplementation in Catalonia showing a small but significant lower risk of cases with cholecalciferol, but no significant difference for mortality, or for calcitriol supplementation. Significant benefit was found for cases, severity, and mortality in patients achieving serum vitamin D levels ≥30ng/ml.
risk of death, 1.0% higher, RR 1.01, p = 0.91, calcifediol, univariate.
risk of death, 4.0% lower, RR 0.96, p = 0.37, cholecalciferol, univariate.
risk of case, 1.0% lower, RR 0.99, p = 0.65, NNT 3499, calcifediol, univariate.
risk of case, 5.0% lower, RR 0.95, p = 0.004, cholecalciferol, multivariate.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Oristrell et al., 17 Jul 2021, retrospective, population-based cohort, Spain, peer-reviewed, 8 authors, dosage varies (calcifediol).
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