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0 0.5 1 1.5 2+ Mortality -73% Improvement Relative Risk Hospitalization -17% c19early.org/d Cereda et al. Vitamin D for COVID-19 Prophylaxis Is prophylaxis with vitamin D beneficial for COVID-19? Retrospective 197 patients in Italy Higher mortality with vitamin D (not stat. sig., p=0.14) Cereda et al., Nutrition, doi:10.1016/j.nut.2020.111055 Favors vitamin D Favors control
Vitamin D supplementation and outcomes in coronavirus disease 2019 (COVID-19) patients from the outbreak area of Lombardy, Italy
Cereda et al., Nutrition, doi:10.1016/j.nut.2020.111055
Cereda et al., Vitamin D supplementation and outcomes in coronavirus disease 2019 (COVID-19) patients from the outbreak area.., Nutrition, doi:10.1016/j.nut.2020.111055
Nov 2020   Source   PDF  
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Retrospective 105 Parkinson's disease patients, 92 caregivers, and 127 hospital inpatients, showing higher, but not statistically significant mortality and hospitalization with treatment. Supplementation was defined as >=25,000IU/month for at least 3 months.
risk of death, 73.0% higher, RR 1.73, p = 0.14, treatment 7 of 18 (38.9%), control 40 of 152 (26.3%), odds ratio converted to relative risk, >=25,000IU/month for at least 3 months.
risk of hospitalization, 17.3% higher, RR 1.17, p = 0.68, treatment 7 of 27 (25.9%), control 36 of 170 (21.2%), odds ratio converted to relative risk.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Cereda et al., 11 Nov 2020, retrospective, Italy, peer-reviewed, mean age 68.8, 7 authors, dosage varies.
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Abstract: Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. Nutrition 82 (2021) 111055 Contents lists available at ScienceDirect Nutrition journal homepage: www.nutritionjrnl.com Applied nutritional investigation Vitamin D supplementation and outcomes in coronavirus disease 2019 (COVID-19) patients from the outbreak area of Lombardy, Italy Emanuele Cereda M.D., Ph.D. a,*, Laura Bogliolo M.D. b, Federica Lobascio M.D. a, Michela Barichella M.D. c,d, Anna Lena Zecchinelli M.D. e, Gianni Pezzoli M.D. d,e, Riccardo Caccialanza M.D. a a Clinical Nutrition and Dietetics Unit, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy Rheumatology Unit, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy c UOS Clinical Nutrition, ASST “Gaetano Pini-CTO”, Milan, Italy d Fondazione Grigioni per il Morbo di Parkinson, Milano, Italy e Parkinson Institute, ASST “Gaetano Pini-CTO”, Milan, Italy b A R T I C L E I N F O Article History: Received 1 September 2020 Received in revised form 3 November 2020 Accepted 3 November 2020 Keywords: Vitamin D Coronavirus (SARS-CoV-2) COVID-19 Hospitalization Mortality Outcome
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