Vitamin D supplementation and outcomes in coronavirus disease 2019 (COVID-19) patients from the outbreak area of Lombardy, Italy
Cereda et al.,
Vitamin D supplementation and outcomes in coronavirus disease 2019 (COVID-19) patients from the outbreak area..,
Nutrition, doi:10.1016/j.nut.2020.111055
Retrospective 105 Parkinson's disease patients, 92 caregivers, and 127 hospital inpatients, showing higher, but not statistically significant mortality and hospitalization with treatment. Supplementation was defined as >=25,000IU/month for at least 3 months.
risk of death, 73.0% higher, RR 1.73, p = 0.14, treatment 7 of 18 (38.9%), control 40 of 152 (26.3%), odds ratio converted to relative risk, >=25,000IU/month for at least 3 months.
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risk of hospitalization, 17.3% higher, RR 1.17, p = 0.68, treatment 7 of 27 (25.9%), control 36 of 170 (21.2%), odds ratio converted to relative risk.
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Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
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Cereda et al., 11 Nov 2020, retrospective, Italy, peer-reviewed, mean age 68.8, 7 authors, dosage varies.
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Nutrition 82 (2021) 111055
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Nutrition
journal homepage: www.nutritionjrnl.com
Applied nutritional investigation
Vitamin D supplementation and outcomes in coronavirus disease 2019
(COVID-19) patients from the outbreak area of Lombardy, Italy
Emanuele Cereda M.D., Ph.D. a,*, Laura Bogliolo M.D. b, Federica Lobascio M.D. a,
Michela Barichella M.D. c,d, Anna Lena Zecchinelli M.D. e, Gianni Pezzoli M.D. d,e,
Riccardo Caccialanza M.D. a
a
Clinical Nutrition and Dietetics Unit, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy
Rheumatology Unit, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy
c
UOS Clinical Nutrition, ASST “Gaetano Pini-CTO”, Milan, Italy
d
Fondazione Grigioni per il Morbo di Parkinson, Milano, Italy
e
Parkinson Institute, ASST “Gaetano Pini-CTO”, Milan, Italy
b
A R T I C L E
I N F O
Article History:
Received 1 September 2020
Received in revised form 3 November 2020
Accepted 3 November 2020
Keywords:
Vitamin D
Coronavirus (SARS-CoV-2)
COVID-19
Hospitalization
Mortality
Outcome
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