Dabbous: Efficacy of favipiravir in COVID-19 treatment: a multi-center randomized study

Efficacy of favipiravir in COVID-19 treatment: a multi-center randomized study

Dabbous et al., Archives of Virology, doi:10.1007/s00705-021-04956-9

Dabbous et al., Efficacy of favipiravir in COVID-19 treatment: a multi-center randomized study, Archives of Virology, doi:10.1007/s00705-021-04956-9

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Dabbous et al., 25 Jan 2021, peer-reviewed, 10 authors.

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Abstract: Archives of Virology (2021) 166:949–954 https://doi.org/10.1007/s00705-021-04956-9 BRIEF REPORT Efficacy of favipiravir in COVID‑19 treatment: a multi‑center randomized study C Received: 14 October 2020 / Accepted: 25 November 2020 / Published online: 25 January 2021 © The Author(s), under exclusive licence to Springer-Verlag GmbH, AT part of Springer Nature 2021 LE Hany M. Dabbous1 · Sherief Abd‑Elsalam2 · Manal H. El‑Sayed3 · Ahmed F. Sherief1 · Fatma F. S. Ebeid3 · Mohamed Samir Abd El Ghafar4 · Shaimaa Soliman5 · Mohamed Elbahnasawy6 · Rehab Badawi2 · Mohamed Awad Tageldin7 A R TI Abstract No specific antiviral drugs have been approved for the treatment of COVID-19. This study aimed to evaluate the efficacy of favipiravir in treatment of COVID-19. This was a multicenter randomized controlled study including 96 patients with COVID- 19 who were randomly assigned into a chloroquine (CQ) group and a favipiravir group. None of the patients in the favipiravir group needed mechanical ventilation (p = 0.129). One patient (2.3%) in the favipiravir group and two patients (4.2%) in the CQ group died (p = 1.00). Favipiravir is a promising drug for COVID-19 that decreases the hospital stay and the need for mechanical ventilation. ClinicalTrials.gov Identifier NCT04351295. TE D

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