Analgesics
Antiandrogens
Antihistamines
Bromhexine
Budesonide
Colchicine
Conv. Plasma
Curcumin
Fluvoxamine
Hydroxychlor..
Ivermectin
Lifestyle
Melatonin
Metformin
Minerals
Monoclonals
Mpro inhibitors
Naso/orophar..
Nigella Sativa
Nitazoxanide
PPIs
Quercetin
RdRp inhibitors
Thermotherapy
Vitamins
More

Other
Feedback
Home
 
next
study
previous
study
c19early.org COVID-19 treatment researchFavipiravirFavipiravir (more..)
Metformin Meta
Bromhexine Meta
Budesonide Meta
Colchicine Meta Nigella Sativa Meta
Conv. Plasma Meta Nitazoxanide Meta
Curcumin Meta PPIs Meta
Fluvoxamine Meta Quercetin Meta
Hydroxychlor.. Meta
Ivermectin Meta Thermotherapy Meta
Melatonin Meta

All Studies   Meta Analysis       

Efficacy of favipiravir in COVID-19 treatment: a multi-center randomized study

Dabbous et al., Archives of Virology, doi:10.1007/s00705-021-04956-9
Jan 2021  
  Post
  Facebook
Share
  Source   PDF   All Studies   Meta AnalysisMeta
This study was retracted.
Potential risks of favipiravir include the creation of dangerous variants, and mutagenicity, carcinogenicity, teratogenicity, and embryotoxicity1-5.
Study covers HCQ and favipiravir.
Dabbous et al., 25 Jan 2021, peer-reviewed, 10 authors.
This PaperFavipiravirAll
RETRACTED ARTICLE: Efficacy of favipiravir in COVID-19 treatment: a multi-center randomized study
Hany M Dabbous, Sherief Abd-Elsalam, Manal H El-Sayed, Ahmed F Sherief, Fatma F S Ebeid, Mohamed Samir Abd El Ghafar, Shaimaa Soliman, Mohamed Elbahnasawy, Rehab Badawi, Mohamed Awad Tageldin
Archives of Virology, doi:10.1007/s00705-021-04956-9
No specific antiviral drugs have been approved for the treatment of COVID-19. This study aimed to evaluate the efficacy of favipiravir in treatment of COVID-19. This was a multicenter randomized controlled study including 96 patients with COVID-19 who were randomly assigned into a chloroquine (CQ) group and a favipiravir group. None of the patients in the favipiravir group needed mechanical ventilation (p = 0.129). One patient (2.3%) in the favipiravir group and two patients (4.2%) in the CQ group died (p = 1.00). Favipiravir is a promising drug for COVID-19 that decreases the hospital stay and the need for mechanical ventilation. ClinicalTrials.gov Identifier NCT04351295.
Compliance with ethical standards
References
Abd-Elsalam, Elkadeem, Glal, Chloroquine as chemoprophylaxis for COVID-19: Will this work?, Infect Disord Drug Targets, doi:10.2174/1871526520666200726224802
Abd-Elsalam, Esmail, Khalaf, Tanta protocol for management of COVID-19. Perspectives from a developing country, Endocr Metab Immune Disord Drug Targets, doi:10.2174/1871530320999201117142305
Abena, Chloroquine and hydroxychloroquine for the prevention or treatment of COVID-19 in Africa: caution for inappropriate off-label use in healthcare settings, Am J Trop Med Hyg
Arab-Zozani, Hassanipour, Ghoddoosi-Nejad, Favipiravir for treating patients with novel coronavirus (COVID-19): protocol for a systematic review and meta-analysis of randomised clinical trials, BMJ Open
Cai, Yang, Liu, Experimental treatment with favipiravir for COVID-19: an open-label control study, doi:10.1016/j.eng.2020.03.007
Cascella, Rajnik, Cuomo, Features, evaluation and treatment coronavirus (COVID-19
Doi, Ikeda, Hayase, Nafamostat mesylate treatment incombination with favipiravir for patients critically ill with Covid-19: a case series, Crit Care
Du, Chen, Favipiravir: pharmacokinetics and concerns about clinical trials for 2019-nCoV infection, Clin Pharmacol Ther
Faul, Erdfelder, Lang, A flexible statistical power analysis program for the social, behavioral, and biomedical sciences, Behav Res Methods
Furuta, Mechanism of action of T-705 against influenza virus, Antimicrob Agents Chemother
Goldhill, Velthuis, Fletcher, The mechanism of resistance to favipiravir in influenza, Proc Natl Acad Sci
Hernandez, Roman, Pasupuleti, Hydroxychloroquine or chloroquine for treatment or prophylaxis of COVID-19: a living systematic review, Ann Intern Med
Inoue, Jinno, Ohta, Combination treatment of short-course systemic corticosteroid and favipiravir in a successfully treated case of critically ill COVID-19 pneumonia with COPD, Respir Med Case Rep
Irie, Nakagawa, Fujita, Pharmacokinetics of favipiravir in critically Ill patients with COVID-19, Clin Transl Sci
Madelain, Oestereich, Graw, Ebola virus dynamics in mice treated with favipiravir, Antiviral Res
Marjot, Moon, Cook, Outcomes following SARS-CoV-2 infection in patients with chronic liver disease: an international registry study, J Hepatol, doi:10.1016/j.jhep.2020.09.024
Mohamed, Mohamed, Mohamoud, SARS-CoV-2: the path of prevention and control, Infect Disord Drug Targets, doi:10.2174/1871526520666200520112848
Noda, Shirai, Nakajima, Case report: two cases of COVID-19 pneumonia including use of favipiravir
Oestereich, Lüdtke, Wurr, Successful treatment of advanced Ebola virus infection with T-705 (favipiravir) in a small animal model, Antiviral Res
Sarin, Choudhury, Lau, Pre-existing liver disease is associated with poor outcome in patients with SARS CoV2 infection; the APCOLIS Study (APASL COVID-19 Liver Injury Spectrum Study), Hepatol Int, doi:10.1007/s12072-020-10072-8
Xie, Chen, Insight into 2019 novel coronavirus-an updated intrim review and lessons from SARS-CoV and MERS-CoV, Int J Infect Dis, doi:10.1016/j.ijid.2020.03.071
Yazdany, Kim, Use of hydroxychloroquine and chloroquine during the COVID-19 pandemic: what every clinician should know, Ann Intern Med
Yin, Wunderink, MERS, SARS and other coronaviruses as causes of pneumonia, Respirology
Yokoyama, Oguri, Kato, Case report a case of COVID-19 pneumonia that did not worsen and was relieved by early administration of favipiravir and ciclesonide
Zhu, Chen, Gorshkov, Elfiky AA (2020) SARS-CoV-2 RNA dependent RNA polymerase (RdRp) targeting: an in silico perspective, SLAS DIS-COV Adv Sci Drug Discov, doi:10.1080/07391102.2020.1761882
Zhu, Zhang, Li, Yang, Song, A novel coronavirus from patients with pneumonia in China, 2019, N Engl J Med
DOI record: { "DOI": "10.1007/s00705-021-04956-9", "ISSN": [ "0304-8608", "1432-8798" ], "URL": "http://dx.doi.org/10.1007/s00705-021-04956-9", "alternative-id": [ "4956" ], "assertion": [ { "group": { "label": "Article History", "name": "ArticleHistory" }, "label": "Received", "name": "received", "order": 1, "value": "14 October 2020" }, { "group": { "label": "Article History", "name": "ArticleHistory" }, "label": "Accepted", "name": "accepted", "order": 2, "value": "25 November 2020" }, { "group": { "label": "Article History", "name": "ArticleHistory" }, "label": "First Online", "name": "first_online", "order": 3, "value": "25 January 2021" }, { "group": { "label": "Article History", "name": "ArticleHistory" }, "label": "Change Date", "name": "change_date", "order": 4, "value": "3 August 2021" }, { "group": { "label": "Article History", "name": "ArticleHistory" }, "label": "Change Type", "name": "change_type", "order": 5, "value": "Clarification" }, { "group": { "label": "Article History", "name": "ArticleHistory" }, "label": "Change Details", "name": "change_details", "order": 6, "value": "Editor's Note:The Editor-in-Chief is currently investigating this article as concerns have been raised about the reporting of this clinical trial. Further editorial action will be taken as appropriate once the investigation into the concerns is complete and all parties have been given an opportunity to respond in full." }, { "group": { "label": "Article History", "name": "ArticleHistory" }, "label": "Change Date", "name": "change_date", "order": 7, "value": "22 November 2021" }, { "group": { "label": "Article History", "name": "ArticleHistory" }, "label": "Change Type", "name": "change_type", "order": 8, "value": "Correction" }, { "group": { "label": "Article History", "name": "ArticleHistory" }, "label": "Change Details", "name": "change_details", "order": 9, "value": "This article has been retracted. Please see the Retraction Notice for more detail:" }, { "URL": "https://doi.org/10.1007/s00705-021-05307-4", "group": { "label": "Article History", "name": "ArticleHistory" }, "label": "Change Details", "name": "change_details", "order": 10, "value": "https://doi.org/10.1007/s00705-021-05307-4" }, { "group": { "label": "Compliance with ethical standards", "name": "EthicsHeading" }, "name": "Ethics", "order": 1 }, { "group": { "label": "Conflict of interest", "name": "EthicsHeading" }, "name": "Ethics", "order": 2, "value": "There are no conflicts of interest." }, { "label": "Free to read", "name": "free", "value": "This content has been made available to all." } ], "author": [ { "affiliation": [], "family": "Dabbous", "given": "Hany M.", "sequence": "first" }, { "ORCID": "http://orcid.org/0000-0003-4366-2218", "affiliation": [], "authenticated-orcid": false, "family": "Abd-Elsalam", "given": "Sherief", "sequence": "additional" }, { "affiliation": [], "family": "El-Sayed", "given": "Manal H.", "sequence": "additional" }, { "affiliation": [], "family": "Sherief", "given": "Ahmed F.", "sequence": "additional" }, { "affiliation": [], "family": "Ebeid", "given": "Fatma F. S.", "sequence": "additional" }, { "affiliation": [], "family": "El Ghafar", "given": "Mohamed Samir Abd", "sequence": "additional" }, { "affiliation": [], "family": "Soliman", "given": "Shaimaa", "sequence": "additional" }, { "affiliation": [], "family": "Elbahnasawy", "given": "Mohamed", "sequence": "additional" }, { "affiliation": [], "family": "Badawi", "given": "Rehab", "sequence": "additional" }, { "affiliation": [], "family": "Tageldin", "given": "Mohamed Awad", "sequence": "additional" } ], "container-title": "Archives of Virology", "container-title-short": "Arch Virol", "content-domain": { "crossmark-restriction": false, "domain": [ "link.springer.com" ] }, "created": { "date-parts": [ [ 2021, 1, 25 ] ], "date-time": "2021-01-25T10:06:58Z", "timestamp": 1611569218000 }, "deposited": { "date-parts": [ [ 2023, 10, 19 ] ], "date-time": "2023-10-19T01:58:46Z", "timestamp": 1697680726000 }, "indexed": { "date-parts": [ [ 2024, 5, 13 ] ], "date-time": "2024-05-13T16:01:05Z", "timestamp": 1715616065990 }, "is-referenced-by-count": 108, "issue": "3", "issued": { "date-parts": [ [ 2021, 1, 25 ] ] }, "journal-issue": { "issue": "3", "published-print": { "date-parts": [ [ 2021, 3 ] ] } }, "language": "en", "license": [ { "URL": "https://www.springer.com/tdm", "content-version": "tdm", "delay-in-days": 0, "start": { "date-parts": [ [ 2021, 1, 25 ] ], "date-time": "2021-01-25T00:00:00Z", "timestamp": 1611532800000 } }, { "URL": "https://www.springer.com/tdm", "content-version": "vor", "delay-in-days": 0, "start": { "date-parts": [ [ 2021, 1, 25 ] ], "date-time": "2021-01-25T00:00:00Z", "timestamp": 1611532800000 } } ], "link": [ { "URL": "https://link.springer.com/content/pdf/10.1007/s00705-021-04956-9.pdf", "content-type": "application/pdf", "content-version": "vor", "intended-application": "text-mining" }, { "URL": "https://link.springer.com/article/10.1007/s00705-021-04956-9/fulltext.html", "content-type": "text/html", "content-version": "vor", "intended-application": "text-mining" }, { "URL": "https://link.springer.com/content/pdf/10.1007/s00705-021-04956-9.pdf", "content-type": "application/pdf", "content-version": "vor", "intended-application": "similarity-checking" } ], "member": "297", "original-title": [], "page": "949-954", "prefix": "10.1007", "published": { "date-parts": [ [ 2021, 1, 25 ] ] }, "published-online": { "date-parts": [ [ 2021, 1, 25 ] ] }, "published-print": { "date-parts": [ [ 2021, 3 ] ] }, "publisher": "Springer Science and Business Media LLC", "reference": [ { "DOI": "10.1056/NEJMoa2001017", "author": "N Zhu", "doi-asserted-by": "publisher", "first-page": "727", "issue": "8", "journal-title": "N Engl J Med.", "key": "4956_CR1", "unstructured": "Zhu N, Zhang D, Wang W, Li X, Yang B, Song J et al (2020) A novel coronavirus from patients with pneumonia in China, 2019. N Engl J Med. 382(8):727–733", "volume": "382", "year": "2020" }, { "DOI": "10.1111/resp.13196", "author": "Y Yin", "doi-asserted-by": "publisher", "first-page": "130", "issue": "2", "journal-title": "Respirology", "key": "4956_CR2", "unstructured": "Yin Y, Wunderink RG (2018) MERS, SARS and other coronaviruses as causes of pneumonia. Respirology 23(2):130–137", "volume": "23", "year": "2018" }, { "author": "M Cascella", "key": "4956_CR3", "unstructured": "Cascella M, Rajnik M, Cuomo A et al (2012) Features, evaluation and treatment coronavirus (COVID-19). StatPearls Publishing, Treasure Island", "volume-title": "Features, evaluation and treatment coronavirus (COVID-19)", "year": "2012" }, { "DOI": "10.7326/M20-1334", "author": "J Yazdany", "doi-asserted-by": "publisher", "first-page": "754", "journal-title": "Ann Intern Med.", "key": "4956_CR4", "unstructured": "Yazdany J, Kim AHJ (2020) Use of hydroxychloroquine and chloroquine during the COVID-19 pandemic: what every clinician should know. Ann Intern Med. 172:754–755", "volume": "172", "year": "2020" }, { "DOI": "10.7326/M20-2496", "author": "AV Hernandez", "doi-asserted-by": "publisher", "first-page": "287", "issue": "4", "journal-title": "Ann Intern Med.", "key": "4956_CR5", "unstructured": "Hernandez AV, Roman YM, Pasupuleti V et al (2020) Hydroxychloroquine or chloroquine for treatment or prophylaxis of COVID-19: a living systematic review. Ann Intern Med. 173(4):287–296", "volume": "173", "year": "2020" }, { "DOI": "10.1002/cpt.1844", "author": "YX Du", "doi-asserted-by": "publisher", "first-page": "242", "issue": "2", "journal-title": "Clin Pharmacol Ther", "key": "4956_CR6", "unstructured": "Du YX, Chen XP (2020) Favipiravir: pharmacokinetics and concerns about clinical trials for 2019-nCoV infection. Clin Pharmacol Ther 108(2):242–247", "volume": "108", "year": "2020" }, { "DOI": "10.1136/bmjopen-2020-039730", "author": "M Arab-Zozani", "doi-asserted-by": "publisher", "first-page": "e039730", "issue": "7", "journal-title": "BMJ Open.", "key": "4956_CR7", "unstructured": "Arab-Zozani M, Hassanipour S, Ghoddoosi-Nejad D (2020) Favipiravir for treating patients with novel coronavirus (COVID-19): protocol for a systematic review and meta-analysis of randomised clinical trials. BMJ Open. 10(7):e039730", "volume": "10", "year": "2020" }, { "DOI": "10.1073/pnas.1811345115", "author": "DH Goldhill", "doi-asserted-by": "publisher", "first-page": "11613", "issue": "45", "journal-title": "Proc Natl Acad Sci", "key": "4956_CR8", "unstructured": "Goldhill DH, Te Velthuis AJ, Fletcher RA et al (2018) The mechanism of resistance to favipiravir in influenza. Proc Natl Acad Sci 115(45):11613–11618", "volume": "115", "year": "2018" }, { "DOI": "10.1177/2472555220942123", "author": "W Zhu", "doi-asserted-by": "publisher", "journal-title": "SLAS DISCOV Adv Sci Drug Discov", "key": "4956_CR9", "unstructured": "Zhu W, Chen CZ, Gorshkov K et al (2020) RNA-dependent RNA polymerase as a target for COVID-19 Drug discovery. SLAS DISCOV Adv Sci Drug Discov. https://doi.org/10.1177/2472555220942123", "year": "2020" }, { "DOI": "10.1080/07391102.2020.1761882", "author": "AA Elfiky", "doi-asserted-by": "publisher", "journal-title": "J Biomol Struct Dyn", "key": "4956_CR10", "unstructured": "Elfiky AA (2020) SARS-CoV-2 RNA dependent RNA polymerase (RdRp) targeting: an in silico perspective. J Biomol Struct Dyn. https://doi.org/10.1080/07391102.2020.1761882", "year": "2020" }, { "DOI": "10.2174/1871526520666200520112848", "author": "AA Mohamed", "doi-asserted-by": "publisher", "journal-title": "Infect Disord Drug Targets", "key": "4956_CR11", "unstructured": "Mohamed AA, Mohamed N, Mohamoud S et al (2020) SARS-CoV-2: the path of prevention and control. Infect Disord Drug Targets. https://doi.org/10.2174/1871526520666200520112848 (Online ahead of print)", "year": "2020" }, { "DOI": "10.1007/s12072-020-10072-8", "author": "SK Sarin", "doi-asserted-by": "publisher", "first-page": "690", "issue": "5", "journal-title": "Hepatol Int", "key": "4956_CR12", "unstructured": "Sarin SK, Choudhury A, Lau GK et al (2020) Pre-existing liver disease is associated with poor outcome in patients with SARS CoV2 infection; the APCOLIS Study (APASL COVID-19 Liver Injury Spectrum Study). Hepatol Int 14(5):690–700. https://doi.org/10.1007/s12072-020-10072-8", "volume": "14", "year": "2020" }, { "DOI": "10.2174/1871526520666200726224802", "author": "S Abd-Elsalam", "doi-asserted-by": "publisher", "journal-title": "Infect Disord Drug Targets.", "key": "4956_CR13", "unstructured": "Abd-Elsalam S, Elkadeem M, Glal KA (2020) Chloroquine as chemoprophylaxis for COVID-19: Will this work? Infect Disord Drug Targets. https://doi.org/10.2174/1871526520666200726224802 (Online ahead of print)", "year": "2020" }, { "DOI": "10.2174/1871530320999201117142305", "author": "S Abd-Elsalam", "doi-asserted-by": "publisher", "journal-title": "Endocr Metab Immune Disord Drug Targets", "key": "4956_CR14", "unstructured": "Abd-Elsalam S, Esmail ES, Khalaf M et al (2020) Tanta protocol for management of COVID-19. Perspectives from a developing country. Endocr Metab Immune Disord Drug Targets. https://doi.org/10.2174/1871530320999201117142305 (Online ahead of print)", "year": "2020" }, { "DOI": "10.1016/j.ijid.2020.03.071", "author": "M Xie", "doi-asserted-by": "publisher", "journal-title": "Int J Infect Dis", "key": "4956_CR15", "unstructured": "Xie M, Chen Q (2020) Insight into 2019 novel coronavirus—an updated intrim review and lessons from SARS-CoV and MERS-CoV. Int J Infect Dis. https://doi.org/10.1016/j.ijid.2020.03.071 ([Epub ahead of print])", "year": "2020" }, { "DOI": "10.1016/j.jhep.2020.09.024", "author": "T Marjot", "doi-asserted-by": "publisher", "journal-title": "J Hepatol", "key": "4956_CR16", "unstructured": "Marjot T, Moon AM, Cook JA et al (2020) Outcomes following SARS-CoV-2 infection in patients with chronic liver disease: an international registry study. J Hepatol. https://doi.org/10.1016/j.jhep.2020.09.024 (Online ahead of print. PMID: 33035628)", "year": "2020" }, { "DOI": "10.1016/j.eng.2020.03.007", "author": "Q Cai", "doi-asserted-by": "publisher", "journal-title": "Engineering (Beijing)", "key": "4956_CR17", "unstructured": "Cai Q, Yang M, Liu D et al (2020) Experimental treatment with favipiravir for COVID-19: an open-label control study. Engineering (Beijing). https://doi.org/10.1016/j.eng.2020.03.007 ([Epub ahead of print])", "year": "2020" }, { "DOI": "10.3758/BF03193146", "author": "F Faul", "doi-asserted-by": "publisher", "first-page": "175", "journal-title": "Behav Res Methods", "key": "4956_CR18", "unstructured": "Faul F, Erdfelder E, Lang A-G et al (2007) A flexible statistical power analysis program for the social, behavioral, and biomedical sciences. Behav Res Methods 39:175–191", "volume": "39", "year": "2007" }, { "key": "4956_CR19", "unstructured": "World Health Organization. Coronavirus disease (COVID-19) situation report—139. https://www.who.int/docs/default-source/coronaviruse/situation-reports/20200607-covid-19-sitrep-139.pdf?sfvrsn=79dc6d08_2. Accessed 8 June 2020." }, { "DOI": "10.1016/j.antiviral.2014.02.014", "author": "L Oestereich", "doi-asserted-by": "publisher", "first-page": "17", "journal-title": "Antiviral Res", "key": "4956_CR20", "unstructured": "Oestereich L, Lüdtke A, Wurr S et al (2014) Successful treatment of advanced Ebola virus infection with T-705 (favipiravir) in a small animal model. Antiviral Res 105:17–21", "volume": "105", "year": "2014" }, { "DOI": "10.1016/j.antiviral.2015.08.015", "author": "V Madelain", "doi-asserted-by": "publisher", "first-page": "70", "journal-title": "Antiviral Res", "key": "4956_CR21", "unstructured": "Madelain V, Oestereich L, Graw F et al (2015) Ebola virus dynamics in mice treated with favipiravir. Antiviral Res 123:70–77", "volume": "123", "year": "2015" }, { "key": "4956_CR22", "unstructured": "Noda A, Shirai T, Nakajima H et al (2020) Case report: two cases of COVID-19 pneumonia including use of favipiravir. The Japanese Association for Infectious Diseases. http://www.kansensho.or.jp/uploads/files/topics/2019ncov/covid19_casereport_en_200408_2.pdf" }, { "key": "4956_CR23", "unstructured": "Yokoyama K, Oguri T, Kato A et al (2020) Case report a case of COVID-19 pneumonia that did not worsen and was relieved by early administration of favipiravir and ciclesonide. http://www.kansensho.or.jp/uploads/files/topics/2019ncov/covid19_casereport_en_200406.pdf." }, { "DOI": "10.4269/ajtmh.20-0290", "author": "PM Abena", "doi-asserted-by": "publisher", "first-page": "1184", "journal-title": "Am J Trop Med Hyg", "key": "4956_CR24", "unstructured": "Abena PM et al (2020) Chloroquine and hydroxychloroquine for the prevention or treatment of COVID-19 in Africa: caution for inappropriate off-label use in healthcare settings. Am J Trop Med Hyg 102:1184–1188", "volume": "102", "year": "2020" }, { "DOI": "10.1128/AAC.49.3.981-986.2005", "author": "Y Furuta", "doi-asserted-by": "publisher", "first-page": "981", "journal-title": "Antimicrob Agents Chemother.", "key": "4956_CR25", "unstructured": "Furuta Y et al (2005) Mechanism of action of T-705 against influenza virus. Antimicrob Agents Chemother. 49:981–986", "volume": "49", "year": "2005" }, { "DOI": "10.1111/cts.12827", "author": "K Irie", "doi-asserted-by": "crossref", "first-page": "880", "issue": "5", "journal-title": "Clin Transl Sci.", "key": "4956_CR26", "unstructured": "Irie K, Nakagawa A, Fujita H et al (2020) Pharmacokinetics of favipiravir in critically Ill patients with COVID-19. Clin Transl Sci. 13(5):880–885", "volume": "13", "year": "2020" }, { "DOI": "10.1186/s13054-020-03078-z", "author": "K Doi", "doi-asserted-by": "publisher", "first-page": "392", "journal-title": "Crit Care", "key": "4956_CR27", "unstructured": "Doi K, Ikeda M, Hayase N et al (2020) Nafamostat mesylate treatment incombination with favipiravir for patients critically ill with Covid-19: a case series. Crit Care 24:392", "volume": "24", "year": "2020" }, { "author": "H Inoue", "first-page": "101200", "journal-title": "Respir Med Case Rep", "key": "4956_CR28", "unstructured": "Inoue H, Jinno M, Ohta S et al (2020) Combination treatment of short-course systemic corticosteroid and favipiravir in a successfully treated case of critically ill COVID-19 pneumonia with COPD. Respir Med Case Rep 31:101200", "volume": "31", "year": "2020" } ], "reference-count": 28, "references-count": 28, "relation": {}, "resource": { "primary": { "URL": "https://link.springer.com/10.1007/s00705-021-04956-9" } }, "score": 1, "short-title": [], "source": "Crossref", "subject": [], "subtitle": [], "title": "RETRACTED ARTICLE: Efficacy of favipiravir in COVID-19 treatment: a multi-center randomized study", "type": "journal-article", "update-policy": "http://dx.doi.org/10.1007/springer_crossmark_policy", "update-to": [ { "DOI": "10.1007/s00705-021-04956-9", "label": "Retraction", "type": "retraction", "updated": { "date-parts": [ [ 2021, 11, 22 ] ], "date-time": "2021-11-22T00:00:00Z", "timestamp": 1637539200000 } } ], "volume": "166" }
Loading..
Please send us corrections, updates, or comments. c19early involves the extraction of 100,000+ datapoints from thousands of papers. Community updates help ensure high accuracy. Treatments and other interventions are complementary. All practical, effective, and safe means should be used based on risk/benefit analysis. No treatment or intervention is 100% available and effective for all current and future variants. We do not provide medical advice. Before taking any medication, consult a qualified physician who can provide personalized advice and details of risks and benefits based on your medical history and situation. FLCCC and WCH provide treatment protocols.
  or use drag and drop   
Submit