The association between COVID-19 vaccination and confirmed patients with hospitalization in Omicron era: A retrospective study

{ 'indexed': {'date-parts': [[2024, 4, 9]], 'date-time': '2024-04-09T00:35:50Z', 'timestamp': 1712622950751}, 'reference-count': 28, 'publisher': 'Ovid Technologies (Wolters Kluwer Health)', 'issue': '52', 'license': [ { 'start': { 'date-parts': [[2023, 12, 29]], 'date-time': '2023-12-29T00:00:00Z', 'timestamp': 1703808000000}, 'content-version': 'unspecified', 'delay-in-days': 0, 'URL': 'http://creativecommons.org/licenses/by/4.0/'}], 'content-domain': {'domain': [], 'crossmark-restriction': False}, 'published-print': {'date-parts': [[2023, 12, 29]]}, 'abstract': '<jats:p>With the emergence of Omicron variant of severe acute respiratory syndrome ' 'coronavirus 2, Taiwan has encountered the greatest coronavirus disease 2019 (COVID-19) ' 'pandemic since 2022 spring. We analyzed the characteristics, vaccinations, and outcomes of ' 'hospitalized COVID-19 patients quarantined in a dedicated ward. This retrospective study ' 'enrolled hospitalized COVID-19 patients in the dedicated wards of a district hospital in ' 'southern Taiwan from May 2022 to July 2022. We assessed in-hospital mortality, hospital ' 'length of stay (LOS), and dedicated ward LOS. Among 209 COVID-19 patients, the in-hospital ' 'mortality rates were 20.7% and 29.7% (<jats:italic toggle="yes">P</jats:italic>\u2005=\u2005' '.145) in patients with and without vaccination. A shorter dedicated ward LOS was noted in the ' 'vaccination group, with marginal statistical significance. Age, Charlson Comorbidity Index, ' 'and quick Sequential Organ Failure Assessment score were recognized as strong prognostic ' 'indicators for mortality in multivariable analysis. Vaccination demonstrated significant ' 'lower odds of death among relatively young populations in subgroup analysis. COVID-19 ' 'vaccination had significant efficacy in hospitalized COVID-19 patients in the relatively ' 'young group, and the effect may decline among individuals with advanced age and multiple ' 'comorbidities.</jats:p>', 'DOI': '10.1097/md.0000000000036777', 'type': 'journal-article', 'created': {'date-parts': [[2024, 1, 9]], 'date-time': '2024-01-09T16:03:27Z', 'timestamp': 1704816207000}, 'page': 'e36777', 'source': 'Crossref', 'is-referenced-by-count': 0, 'title': 'The association between COVID-19 vaccination and confirmed patients with hospitalization in ' 'Omicron era: A retrospective study', 'prefix': '10.1097', 'volume': '102', 'author': [ { 'ORCID': 'http://orcid.org/0009-0003-8319-3927', 'authenticated-orcid': False, 'given': 'Ming-Hung', 'family': 'Chang', 'sequence': 'first', 'affiliation': [ { 'name': 'Division of Chest Medicine, Department of Internal Medicine, Chi ' 'Mei Medical Center, Chiali, Tainan, Taiwan.'}]}, { 'given': 'Kuang-Ming', 'family': 'Liao', 'sequence': 'additional', 'affiliation': [ { 'name': 'Division of Chest Medicine, Department of Internal Medicine, Chi ' 'Mei Medical Center, Chiali, Tainan, Taiwan.'}]}], 'member': '276', 'reference': [ { 'key': 'R3-20240109', 'doi-asserted-by': 'crossref', 'first-page': '2027160', 'DOI': '10.1080/21645515.2022.2027160', 'article-title': 'The efficacy and effectiveness of the COVID-19 vaccines in reducing ' 'infection, severity, hospitalization, and mortality: a systematic ' 'review.', 'volume': '18', 'author': 'Mohammed', 'year': '2022', 'journal-title': 'Hum Vaccin Immunother'}, { 'key': 'R4-20240109', 'doi-asserted-by': 'crossref', 'first-page': '2043', 'DOI': '10.1001/jama.2021.19499', 'article-title': 'Association between mRNA vaccination and COVID-19 hospitalization and ' 'disease severity.', 'volume': '326', 'author': 'Tenforde', 'year': '2021', 'journal-title': 'JAMA'}, { 'key': 'R5-20240109', 'doi-asserted-by': 'crossref', 'first-page': '1646', 'DOI': '10.1016/S0140-6736(21)00677-2', 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'https://journals.lww.com/10.1097/MD.0000000000036777', 'content-type': 'unspecified', 'content-version': 'vor', 'intended-application': 'similarity-checking'}], 'deposited': { 'date-parts': [[2024, 1, 9]], 'date-time': '2024-01-09T16:03:37Z', 'timestamp': 1704816217000}, 'score': 1, 'resource': {'primary': {'URL': 'https://journals.lww.com/10.1097/MD.0000000000036777'}}, 'subtitle': [], 'short-title': [], 'issued': {'date-parts': [[2023, 12, 29]]}, 'references-count': 28, 'journal-issue': {'issue': '52', 'published-print': {'date-parts': [[2023]]}}, 'URL': 'http://dx.doi.org/10.1097/MD.0000000000036777', 'relation': { 'has-preprint': [ { 'id-type': 'doi', 'id': '10.21203/rs.3.rs-2800430/v1', 'asserted-by': 'object'}]}, 'ISSN': ['0025-7974', '1536-5964'], 'subject': ['General Medicine'], 'published': {'date-parts': [[2023, 12, 29]]}}