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All Studies   Meta Analysis    Recent:   
0 0.5 1 1.5 2+ Case -2% Improvement Relative Risk Case (b) -4% UDCA for COVID-19  Liu et al.  Prophylaxis Does ursodeoxycholic acid reduce COVID-19 infections? Retrospective 226 patients in China No significant difference in cases c19early.org Liu et al., Liver Int., June 2023 Favors ursodeoxycholic acid Favors control

Ursodeoxycholic acid administration did not reduce susceptibility to SARS‐CoV‐2 infection in children

Liu et al., Liver International, doi:10.1111/liv.15660
Jun 2023  
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Retrospective 280 Chinese families with children previously seen in a liver clinic assessing whether ursodeoxycholic acid (UDCA) reduced SARS-CoV-2 infection risk. Among infected families, the study found no significant difference in confirmed or suspected SARS-CoV-2 infections between children taking UDCA (80.9%) and those not taking it (77.6%) (p=0.843).
risk of case, 2.1% higher, RR 1.02, p = 0.88, treatment 95 of 146 (65.1%), control 51 of 80 (63.7%), confirmed.
risk of case, 4.3% higher, RR 1.04, p = 0.61, treatment 118 of 146 (80.8%), control 62 of 80 (77.5%), confirmed + suspected.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Liu et al., 29 Jun 2023, retrospective, China, peer-reviewed, survey, 2 authors.
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