PPIs for COVID-19
1st treatment shown to increase risk in
September 2020, now with p = 0.00000012 from 39 studies.
5,100+ studies for
112 treatments. c19early.org
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risk of death/intubation, 34.0% higher, HR 1.34, p = 0.01, treatment 8 of 84 (9.5%), control 332 of 1,536 (21.6%), NNT 8.3, adjusted per study, propensity score matching, multivariable, Cox proportional hazards.
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Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates |