Development and validation of a nomogram to assess the occurrence of liver dysfunction in patients with COVID-19 pneumonia in the ICU

DOI record: { "DOI": "10.1186/s12879-025-10684-1", "ISSN": [ "1471-2334" ], "URL": "http://dx.doi.org/10.1186/s12879-025-10684-1", "alternative-id": [ "10684" ], "article-number": "332", "assertion": [ { "group": { "label": "Article History", "name": "ArticleHistory" }, "label": "Received", "name": "received", "order": 1, "value": "12 August 2024" }, { "group": { "label": "Article History", "name": "ArticleHistory" }, "label": "Accepted", "name": "accepted", "order": 2, "value": "18 February 2025" }, { "group": { "label": "Article History", "name": "ArticleHistory" }, "label": "First Online", "name": "first_online", "order": 3, "value": "10 March 2025" }, { "group": { "label": "Declarations", "name": "EthicsHeading" }, "name": "Ethics", "order": 1 }, { "group": { "label": "Ethics approval and consent to participate", "name": "EthicsHeading" }, "name": "Ethics", "order": 2, "value": "This study was conducted in accordance with the principles of the Declaration of Helsinki and was approved by the Medical Ethics Committee of Tianjin Medical University General Hospital (Approval Number: IRB2022-YX-268–01) on December 29, 2022. All procedures involving human participants adhered to the ethical standards of the institutional and/or national research committee and the 1964 Helsinki Declaration and its later amendments or comparable ethical standards.Given the retrospective nature of this study and the use of anonymized medical records, the Medical Ethics Committee approved a waiver of written informed consent for patients with COVID-19. The waiver was granted as the research involved no more than minimal risk to the participants, and the data were anonymized to ensure privacy and confidentiality." }, { "group": { "label": "Consent for publication", "name": "EthicsHeading" }, "name": "Ethics", "order": 3, "value": "Written informed consent for publication was obtained from all participants." }, { "group": { "label": "Competing interests", "name": "EthicsHeading" }, "name": "Ethics", "order": 4, "value": "The authors declare no competing interests." } ], "author": [ { "affiliation": [], "family": "Wang", "given": "Zhiwei", "sequence": "first" }, { "affiliation": [], "family": "Zhao", "given": "Lina", "sequence": "additional" }, { "affiliation": [], "family": "Xie", "given": "Keliang", "sequence": "additional" } ], "container-title": "BMC Infectious Diseases", "container-title-short": "BMC Infect Dis", "content-domain": { "crossmark-restriction": false, "domain": [ "link.springer.com" ] }, "created": { "date-parts": [ [ 2025, 3, 10 ] ], "date-time": "2025-03-10T11:37:28Z", "timestamp": 1741606648000 }, "deposited": { "date-parts": [ [ 2025, 3, 10 ] ], "date-time": "2025-03-10T12:25:30Z", "timestamp": 1741609530000 }, "indexed": { "date-parts": [ [ 2025, 3, 18 ] ], "date-time": "2025-03-18T04:21:23Z", "timestamp": 1742271683344, "version": "3.40.1" }, "is-referenced-by-count": 0, "issue": "1", "issued": { "date-parts": [ [ 2025, 3, 10 ] ] }, "journal-issue": { "issue": "1", "published-online": { "date-parts": [ [ 2025, 12 ] ] } }, "language": "en", "license": [ { "URL": "https://creativecommons.org/licenses/by-nc-nd/4.0", "content-version": "tdm", "delay-in-days": 0, "start": { "date-parts": [ [ 2025, 3, 10 ] ], "date-time": "2025-03-10T00:00:00Z", "timestamp": 1741564800000 } }, { "URL": "https://creativecommons.org/licenses/by-nc-nd/4.0", "content-version": "vor", "delay-in-days": 0, "start": { "date-parts": [ [ 2025, 3, 10 ] ], "date-time": "2025-03-10T00:00:00Z", "timestamp": 1741564800000 } } ], "link": [ { "URL": "https://link.springer.com/content/pdf/10.1186/s12879-025-10684-1.pdf", "content-type": "application/pdf", "content-version": "vor", "intended-application": "text-mining" }, { "URL": "https://link.springer.com/article/10.1186/s12879-025-10684-1/fulltext.html", "content-type": "text/html", "content-version": "vor", "intended-application": "text-mining" }, { "URL": "https://link.springer.com/content/pdf/10.1186/s12879-025-10684-1.pdf", "content-type": "application/pdf", "content-version": "vor", "intended-application": "similarity-checking" } ], "member": "297", "original-title": [], "prefix": "10.1186", "published": { "date-parts": [ [ 2025, 3, 10 ] ] }, "published-online": { "date-parts": [ [ 2025, 3, 10 ] ] }, "publisher": "Springer Science and Business Media LLC", "reference": [ { "key": "10684_CR1", "unstructured": "WHO coronavirus (COVID-19) dashboard. https://covid19.who.int/." }, { "DOI": "10.1038/s41392-022-00907-1", "author": "Q Ning", "doi-asserted-by": "publisher", "first-page": "57", "issue": "1", "journal-title": "Signal Transduct Target Ther", "key": "10684_CR2", "unstructured": "Ning Q, Wu D, Wang X, Xi D, Chen T, Chen G, Wang H, Lu H, Wang M, Zhu L, et al. 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