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All Studies   Meta Analysis    Recent:   

A retrospective analysis of clinical outcomes between hospitalized patients with COVID‐19 who received famotidine or pantoprazole

Wagner et al., JGH Open, doi:10.1002/jgh3.12905 (abstract 10/31/2021)
Oct 2021  
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Mortality 64% Improvement Relative Risk Ventilation 6% Famotidine for COVID-19  Wagner et al.  LATE TREATMENT Is late treatment with famotidine beneficial for COVID-19? Retrospective 1,457 patients in the USA (March 2020 - March 2021) Lower mortality with famotidine (p<0.000001) c19early.org Wagner et al., JGH Open, October 2021 Favorsfamotidine Favorscontrol 0 0.5 1 1.5 2+
Famotidine for COVID-19
25th treatment shown to reduce risk in October 2021
 
*, now with p = 0.00028 from 30 studies, recognized in 2 countries.
No treatment is 100% effective. Protocols combine treatments. * >10% efficacy, ≥3 studies.
4,500+ studies for 81 treatments. c19early.org
Retrospective 2,184 hospitalized patients in the USA, 638 treated with famotidine, showing lower mortality with treatment.
risk of death, 64.5% lower, RR 0.36, p < 0.001, treatment 82 of 638 (12.9%), control 182 of 819 (22.2%), adjusted per study, odds ratio converted to relative risk, multivariable.
risk of mechanical ventilation, 6.4% lower, RR 0.94, p = 0.77, treatment 48 of 638 (7.5%), control 75 of 819 (9.2%), adjusted per study, odds ratio converted to relative risk, multivariable.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Wagner et al., 31 Oct 2021, retrospective, USA, peer-reviewed, 5 authors, study period 1 March, 2020 - 1 March, 2021. Contact: jj.wagner5492@gmail.com.
This PaperFamotidineAll
Gastrointestinal Symptoms and Association With Respiratory Symptoms in Patients Diagnosed With SARS-CoV 2 (COVID-19)
MD Ernesto Robalino Gonzaga, MD Irene Riestra Guiance, MD Richard Henriquez, MD Mahmoud Ibrahim, MD Yuya Nway, DO Minh Ho, Jane Ha, MD, PhD Yeongkeun Kwon, BS Dohyang Kim, PhD Jinseub Hwang, PhD Jin-Won Kwon, MD, PhD Sungsoo Park
Figure 1. Panel a: Hospitalized COVID-19 patients with GI Symptoms on Admission demographic characteristics and ICU or non ICU admissions comparing with presence or no of respiratory symptoms. Panel b: Odds Ratio Estimates for ICU Admission in Patients with COVID-19 presenting with GI symptoms.
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Late treatment
is less effective
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