A cohort study of COVID-19 infection in pediatric oncology patients plus the utility and safety of remdesivir treatment
et al., Acta Oncologica, doi:10.1080/0284186X.2023.2169079
, A cohort study of COVID-19 infection in pediatric oncology patients plus the utility and safety of remdesivir.., Acta Oncologica, doi:10.1080/0284186X.2023.2169079
Retrospective 18 immunocompromised pediatric COVID-19 patients in Singapore, showing slower viral clearance with remdesivir, without statistical significance.[Gérard, Wu, Zhou] show significantly increased risk of acute kidney injury with remdesivir.
1.
Gérard et al., Clinical Pharmacology & Therapeutics, doi:10.1002/cpt.2145,
Remdesivir and Acute Renal Failure: A Potential Safety Signal From Disproportionality Analysis of the WHO Safety Database,
https://onlinelibrary.wiley.com/doi/pdf/10.1002/cpt.2145.
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recovery time, 75.0% higher, relative time 1.75, p = 0.60, treatment 4, control 14, defervescence.
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hospitalization time, 55.6% higher, relative time 1.56, p = 0.31, treatment 4, control 14.
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time to viral-, 60.7% higher, relative time 1.61, p = 0.14, treatment 4, control 14.
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| Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates |
Ong et al., 20 Jan 2023, retrospective, Singapore, peer-reviewed, 12 authors.
Contact:
rina.ong.yl@kkh.com.sg, yung.chee.fu@singhealth.com.sg.
Abstract: Acta Oncologica
ISSN: (Print) (Online) Journal homepage: https://www.tandfonline.com/loi/ionc20
A cohort study of COVID-19 infection in pediatric
oncology patients plus the utility and safety of
remdesivir treatment
Rina Yue Ling Ong, Valerie Xue Fen Seah, Chia Yin Chong, Koh Cheng Thoon,
Natalie Woon Hui Tan, Jiahui Li, Karen Donceras Nadua, Shui Yen Soh,
Michaela Su-Fern Seng, Thi Ngoc Anh Pham, Chee Fu Yung & Kai-Qian Kam
To cite this article: Rina Yue Ling Ong, Valerie Xue Fen Seah, Chia Yin Chong, Koh Cheng
Thoon, Natalie Woon Hui Tan, Jiahui Li, Karen Donceras Nadua, Shui Yen Soh, Michaela Su-Fern
Seng, Thi Ngoc Anh Pham, Chee Fu Yung & Kai-Qian Kam (2023) A cohort study of COVID-19
infection in pediatric oncology patients plus the utility and safety of remdesivir treatment, Acta
Oncologica, 62:1, 53-57, DOI: 10.1080/0284186X.2023.2169079
To link to this article: https://doi.org/10.1080/0284186X.2023.2169079
Published online: 20 Jan 2023.
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ACTA ONCOLOGICA
2023, VOL. 62, NO. 1, 53–57
https://doi.org/10.1080/0284186X.2023.2169079
LETTER TO THE EDITOR
A cohort study of COVID-19 infection in pediatric oncology patients plus the
utility and safety of remdesivir treatment
Rina Yue Ling Onga , Valerie Xue Fen Seaha , Chia Yin Chongb,c,d,e , Koh Cheng Thoonb,c,d,e ,
Natalie Woon Hui Tanb,c,d,e , Jiahui Lib,c,d,e, Karen Donceras Naduab,c,d,e , Shui Yen Sohc,d,e,f ,
Michaela Su-Fern Sengc,d,e,f , Thi Ngoc Anh Phamg, Chee Fu Yungb,d,e
and Kai-Qian Kamb,c,d,e
a
Department of Pharmacy, KK Women’s and Children’s Hospital, Singapore, Singapore; bInfectious Disease Service, Department of Pediatrics,
KK Women’s and Children’s Hospital, Singapore, Singapore; cYong Loo Lin School of Medicine, National University of Singapore, Singapore,
Singapore; dDuke-National University of Singapore Medical School, Singapore, Singapore; eLee Kong Chian School of Medicine, Nanyang
Technological University, Singapore, Singapore; fHaematology/Oncology Service, Department of Pediatrics, KK Women’s and Children’s
Hospital, Singapore, Singapore; gNursing Clinical Services, Division of Nursing, KK Women’s and Children’s Hospital, Singapore, Singapore
ARTICLE HISTORY Received 22 November 2022; Accepted 11 January 2023
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