Analgesics
Antiandrogens
Antihistamines
Azvudine
Bromhexine
Budesonide
Colchicine
Conv. Plasma
Curcumin
Famotidine
Favipiravir
Fluvoxamine
Hydroxychlor..
Ivermectin
Lifestyle
Melatonin
Metformin
Minerals
Molnupiravir
Monoclonals
Naso/orophar..
Nigella Sativa
Nitazoxanide
PPIs
Paxlovid
Quercetin
Remdesivir
Thermotherapy
Vitamins
More

Other
Feedback
Home
Top
Results
Abstract
All remdesivir studies
Meta analysis
 
Feedback
Home
next
study
previous
study
c19early.org COVID-19 treatment researchRemdesivirRemdesivir (more..)
Melatonin Meta
Metformin Meta
Antihistamines Meta
Azvudine Meta Molnupiravir Meta
Bromhexine Meta
Budesonide Meta
Colchicine Meta Nigella Sativa Meta
Conv. Plasma Meta Nitazoxanide Meta
Curcumin Meta PPIs Meta
Famotidine Meta Paxlovid Meta
Favipiravir Meta Quercetin Meta
Fluvoxamine Meta Remdesivir Meta
Hydroxychlor.. Meta Thermotherapy Meta
Ivermectin Meta

All Studies   Meta Analysis    Recent:   

A cohort study of COVID-19 infection in pediatric oncology patients plus the utility and safety of remdesivir treatment

Ong et al., Acta Oncologica, doi:10.1080/0284186X.2023.2169079
Jan 2023  
  Post
  Facebook
Share
  Source   PDF   All Studies   Meta AnalysisMeta
Recovery time -75% Improvement Relative Risk Hospitalization time -56% Time to viral- -61% Remdesivir for COVID-19  Ong et al.  EARLY TREATMENT Is early treatment with remdesivir beneficial for COVID-19? Retrospective 18 patients in Singapore Slower recovery (p=0.6) and longer hospitalization (p=0.31), not sig. c19early.org Ong et al., Acta Oncologica, January 2023 Favorsremdesivir Favorscontrol 0 0.5 1 1.5 2+
Retrospective 18 immunocompromised pediatric COVID-19 patients in Singapore, showing slower viral clearance with remdesivir, without statistical significance.
Gérard, Zhou, Wu, Kamo, Choi show significantly increased risk of acute kidney injury with remdesivir.
recovery time, 75.0% higher, relative time 1.75, p = 0.60, treatment 4, control 14, defervescence.
hospitalization time, 55.6% higher, relative time 1.56, p = 0.31, treatment 4, control 14.
time to viral-, 60.7% higher, relative time 1.61, p = 0.14, treatment 4, control 14.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Ong et al., 20 Jan 2023, retrospective, Singapore, peer-reviewed, 12 authors. Contact: rina.ong.yl@kkh.com.sg, yung.chee.fu@singhealth.com.sg.
This PaperRemdesivirAll
Abstract: Acta Oncologica ISSN: (Print) (Online) Journal homepage: https://www.tandfonline.com/loi/ionc20 A cohort study of COVID-19 infection in pediatric oncology patients plus the utility and safety of remdesivir treatment Rina Yue Ling Ong, Valerie Xue Fen Seah, Chia Yin Chong, Koh Cheng Thoon, Natalie Woon Hui Tan, Jiahui Li, Karen Donceras Nadua, Shui Yen Soh, Michaela Su-Fern Seng, Thi Ngoc Anh Pham, Chee Fu Yung & Kai-Qian Kam To cite this article: Rina Yue Ling Ong, Valerie Xue Fen Seah, Chia Yin Chong, Koh Cheng Thoon, Natalie Woon Hui Tan, Jiahui Li, Karen Donceras Nadua, Shui Yen Soh, Michaela Su-Fern Seng, Thi Ngoc Anh Pham, Chee Fu Yung & Kai-Qian Kam (2023) A cohort study of COVID-19 infection in pediatric oncology patients plus the utility and safety of remdesivir treatment, Acta Oncologica, 62:1, 53-57, DOI: 10.1080/0284186X.2023.2169079 To link to this article: https://doi.org/10.1080/0284186X.2023.2169079 Published online: 20 Jan 2023. Submit your article to this journal Article views: 470 View related articles View Crossmark data Full Terms & Conditions of access and use can be found at https://www.tandfonline.com/action/journalInformation?journalCode=ionc20 ACTA ONCOLOGICA 2023, VOL. 62, NO. 1, 53–57 https://doi.org/10.1080/0284186X.2023.2169079 LETTER TO THE EDITOR A cohort study of COVID-19 infection in pediatric oncology patients plus the utility and safety of remdesivir treatment Rina Yue Ling Onga , Valerie Xue Fen Seaha , Chia Yin Chongb,c,d,e , Koh Cheng Thoonb,c,d,e , Natalie Woon Hui Tanb,c,d,e , Jiahui Lib,c,d,e, Karen Donceras Naduab,c,d,e , Shui Yen Sohc,d,e,f , Michaela Su-Fern Sengc,d,e,f , Thi Ngoc Anh Phamg, Chee Fu Yungb,d,e and Kai-Qian Kamb,c,d,e a Department of Pharmacy, KK Women’s and Children’s Hospital, Singapore, Singapore; bInfectious Disease Service, Department of Pediatrics, KK Women’s and Children’s Hospital, Singapore, Singapore; cYong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore; dDuke-National University of Singapore Medical School, Singapore, Singapore; eLee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore; fHaematology/Oncology Service, Department of Pediatrics, KK Women’s and Children’s Hospital, Singapore, Singapore; gNursing Clinical Services, Division of Nursing, KK Women’s and Children’s Hospital, Singapore, Singapore ARTICLE HISTORY Received 22 November 2022; Accepted 11 January 2023
{ 'indexed': {'date-parts': [[2023, 4, 4]], 'date-time': '2023-04-04T04:44:53Z', 'timestamp': 1680583493450}, 'reference-count': 37, 'publisher': 'Informa UK Limited', 'issue': '1', 'funder': [ { 'name': 'Singhealth Duke-NUS Academic Medicine COVID-19 Rapid Response Research Grant', 'award': ['AM/COV001/2020']}, { 'name': 'Singhealth Duke-NUS Academic Medicine COVID-19 Rapid Response Research Grant', 'award': ['AM/COV001/2020']}], 'content-domain': {'domain': ['www.tandfonline.com'], 'crossmark-restriction': True}, 'published-print': {'date-parts': [[2023, 1, 2]]}, 'DOI': '10.1080/0284186x.2023.2169079', 'type': 'journal-article', 'created': {'date-parts': [[2023, 1, 20]], 'date-time': '2023-01-20T09:42:30Z', 'timestamp': 1674207750000}, 'page': '53-57', 'update-policy': 'http://dx.doi.org/10.1080/tandf_crossmark_01', 'source': 'Crossref', 'is-referenced-by-count': 0, 'title': 'A cohort study of COVID-19 infection in pediatric oncology patients plus the utility and safety ' 'of remdesivir treatment', 'prefix': '10.1080', 'volume': '62', 'author': [ { 'ORCID': 'http://orcid.org/0000-0003-1599-619X', 'authenticated-orcid': False, 'given': 'Rina Yue Ling', 'family': 'Ong', 'sequence': 'first', 'affiliation': [ { 'name': 'Department of Pharmacy, KK Women’s and Children’s Hospital, ' 'Singapore, Singapore'}]}, { 'ORCID': 'http://orcid.org/0000-0002-7775-6987', 'authenticated-orcid': False, 'given': 'Valerie Xue Fen', 'family': 'Seah', 'sequence': 'additional', 'affiliation': [ { 'name': 'Department of Pharmacy, KK Women’s and Children’s Hospital, ' 'Singapore, Singapore'}]}, { 'ORCID': 'http://orcid.org/0000-0003-3919-3324', 'authenticated-orcid': False, 'given': 'Chia Yin', 'family': 'Chong', 'sequence': 'additional', 'affiliation': [ { 'name': 'Infectious Disease Service, Department of Pediatrics, KK Women’s ' 'and Children’s Hospital, Singapore, Singapore'}, { 'name': 'Yong Loo Lin School of Medicine, National University of ' 'Singapore, Singapore, Singapore'}, { 'name': 'Duke-National University of Singapore Medical School, Singapore, ' 'Singapore'}, { 'name': 'Lee Kong Chian School of Medicine, Nanyang Technological ' 'University, Singapore, Singapore'}]}, { 'ORCID': 'http://orcid.org/0000-0002-2844-010X', 'authenticated-orcid': False, 'given': 'Koh Cheng', 'family': 'Thoon', 'sequence': 'additional', 'affiliation': [ { 'name': 'Infectious Disease Service, Department of Pediatrics, KK Women’s ' 'and Children’s Hospital, Singapore, Singapore'}, { 'name': 'Yong Loo Lin School of Medicine, National University of ' 'Singapore, Singapore, Singapore'}, { 'name': 'Duke-National University of Singapore Medical School, Singapore, ' 'Singapore'}, { 'name': 'Lee Kong Chian School of Medicine, Nanyang Technological ' 'University, Singapore, Singapore'}]}, { 'ORCID': 'http://orcid.org/0000-0002-7380-5008', 'authenticated-orcid': False, 'given': 'Natalie Woon Hui', 'family': 'Tan', 'sequence': 'additional', 'affiliation': [ { 'name': 'Infectious Disease Service, Department of Pediatrics, KK Women’s ' 'and Children’s Hospital, Singapore, Singapore'}, { 'name': 'Yong Loo Lin School of Medicine, National University of ' 'Singapore, Singapore, Singapore'}, { 'name': 'Duke-National University of Singapore Medical School, Singapore, ' 'Singapore'}, { 'name': 'Lee Kong Chian School of Medicine, Nanyang Technological ' 'University, Singapore, Singapore'}]}, { 'given': 'Jiahui', 'family': 'Li', 'sequence': 'additional', 'affiliation': [ { 'name': 'Infectious Disease Service, Department of Pediatrics, KK Women’s ' 'and Children’s Hospital, Singapore, Singapore'}, { 'name': 'Yong Loo Lin School of Medicine, National University of ' 'Singapore, Singapore, Singapore'}, { 'name': 'Duke-National University of Singapore Medical School, Singapore, ' 'Singapore'}, { 'name': 'Lee Kong Chian School of Medicine, Nanyang Technological ' 'University, Singapore, Singapore'}]}, { 'ORCID': 'http://orcid.org/0000-0002-1313-7458', 'authenticated-orcid': False, 'given': 'Karen Donceras', 'family': 'Nadua', 'sequence': 'additional', 'affiliation': [ { 'name': 'Infectious Disease Service, Department of Pediatrics, KK Women’s ' 'and Children’s Hospital, Singapore, Singapore'}, { 'name': 'Yong Loo Lin School of Medicine, National University of ' 'Singapore, Singapore, Singapore'}, { 'name': 'Duke-National University of Singapore Medical School, Singapore, ' 'Singapore'}, { 'name': 'Lee Kong Chian School of Medicine, Nanyang Technological ' 'University, Singapore, Singapore'}]}, { 'ORCID': 'http://orcid.org/0000-0002-4237-8904', 'authenticated-orcid': False, 'given': 'Shui Yen', 'family': 'Soh', 'sequence': 'additional', 'affiliation': [ { 'name': 'Yong Loo Lin School of Medicine, National University of ' 'Singapore, Singapore, Singapore'}, { 'name': 'Duke-National University of Singapore Medical School, Singapore, ' 'Singapore'}, { 'name': 'Lee Kong Chian School of Medicine, Nanyang Technological ' 'University, Singapore, Singapore'}, { 'name': 'Haematology/Oncology Service, Department of Pediatrics, KK ' 'Women’s and Children’s Hospital, Singapore, Singapore'}]}, { 'ORCID': 'http://orcid.org/0000-0002-6245-2446', 'authenticated-orcid': False, 'given': 'Michaela Su-Fern', 'family': 'Seng', 'sequence': 'additional', 'affiliation': [ { 'name': 'Yong Loo Lin School of Medicine, National University of ' 'Singapore, Singapore, Singapore'}, { 'name': 'Duke-National University of Singapore Medical School, Singapore, ' 'Singapore'}, { 'name': 'Lee Kong Chian School of Medicine, Nanyang Technological ' 'University, Singapore, Singapore'}, { 'name': 'Haematology/Oncology Service, Department of Pediatrics, KK ' 'Women’s and Children’s Hospital, Singapore, Singapore'}]}, { 'given': 'Thi Ngoc Anh', 'family': 'Pham', 'sequence': 'additional', 'affiliation': [ { 'name': 'Nursing Clinical Services, Division of Nursing, KK Women’s and ' 'Children’s Hospital, Singapore, Singapore'}]}, { 'ORCID': 'http://orcid.org/0000-0001-9605-7690', 'authenticated-orcid': False, 'given': 'Chee Fu', 'family': 'Yung', 'sequence': 'additional', 'affiliation': [ { 'name': 'Infectious Disease Service, Department of Pediatrics, KK Women’s ' 'and Children’s Hospital, Singapore, Singapore'}, { 'name': 'Duke-National University of Singapore Medical School, Singapore, ' 'Singapore'}, { 'name': 'Lee Kong Chian School of Medicine, Nanyang Technological ' 'University, Singapore, Singapore'}]}, { 'ORCID': 'http://orcid.org/0000-0002-2402-7262', 'authenticated-orcid': False, 'given': 'Kai-Qian', 'family': 'Kam', 'sequence': 'additional', 'affiliation': [ { 'name': 'Infectious Disease Service, Department of Pediatrics, KK Women’s ' 'and Children’s Hospital, Singapore, Singapore'}, { 'name': 'Yong Loo Lin School of Medicine, National University of ' 'Singapore, Singapore, Singapore'}, { 'name': 'Duke-National University of Singapore Medical School, Singapore, ' 'Singapore'}, { 'name': 'Lee Kong Chian School of Medicine, Nanyang Technological ' 'University, Singapore, Singapore'}]}], 'member': '301', 'published-online': {'date-parts': [[2023, 1, 20]]}, 'reference': [ {'key': 'CIT0001', 'doi-asserted-by': 'publisher', 'DOI': '10.1001/jama.2020.2648'}, {'key': 'CIT0002', 'doi-asserted-by': 'publisher', 'DOI': '10.1111/apa.15270'}, {'key': 'CIT0003', 'doi-asserted-by': 'publisher', 'DOI': '10.1097/INF.0000000000003043'}, {'key': 'CIT0004', 'doi-asserted-by': 'publisher', 'DOI': '10.1016/S2352-4642(20)30177-2'}, {'key': 'CIT0005', 'doi-asserted-by': 'publisher', 'DOI': '10.1056/NEJMc2031670'}, {'key': 'CIT0006', 'doi-asserted-by': 'publisher', 'DOI': '10.1056/NEJMoa2116846'}, { 'key': 'CIT0007', 'unstructured': 'National Institute of Health (NIH). NIH COVID-19 Treatment Guidelines: ' 'Clinical Spectrum of SARS-CoV-2 Infection. 2022. ' 'https://www.covid19treatmentguidelines.nih.gov/overview/clinical-spectrum'}, {'key': 'CIT0008', 'doi-asserted-by': 'publisher', 'DOI': '10.1002/pbc.28843'}, {'key': 'CIT0009', 'doi-asserted-by': 'publisher', 'DOI': '10.1093/cid/ciaa638'}, {'key': 'CIT0010', 'doi-asserted-by': 'publisher', 'DOI': '10.1016/S1470-2045(21)00454-X'}, {'key': 'CIT0011', 'doi-asserted-by': 'publisher', 'DOI': '10.3389/pore.2022.1610261'}, {'key': 'CIT0012', 'doi-asserted-by': 'publisher', 'DOI': '10.4084/MJHID.2022.009'}, {'key': 'CIT0013', 'doi-asserted-by': 'publisher', 'DOI': '10.1186/s13045-021-01181-4'}, {'key': 'CIT0014', 'doi-asserted-by': 'publisher', 'DOI': '10.1016/j.clml.2021.07.025'}, {'key': 'CIT0015', 'doi-asserted-by': 'publisher', 'DOI': '10.1002/pbc.28432'}, {'key': 'CIT0016', 'doi-asserted-by': 'publisher', 'DOI': '10.1002/pbc.28514'}, {'key': 'CIT0017', 'doi-asserted-by': 'publisher', 'DOI': '10.1002/pbc.28392'}, {'key': 'CIT0018', 'doi-asserted-by': 'publisher', 'DOI': '10.1002/pbc.28710'}, {'key': 'CIT0019', 'doi-asserted-by': 'publisher', 'DOI': '10.3390/biomedicines10082002'}, {'key': 'CIT0020', 'doi-asserted-by': 'publisher', 'DOI': '10.1093/jac/dkac253'}, {'key': 'CIT0021', 'doi-asserted-by': 'publisher', 'DOI': '10.3390/cancers14194720'}, {'key': 'CIT0022', 'doi-asserted-by': 'publisher', 'DOI': '10.2147/JIR.S378347'}, {'key': 'CIT0023', 'doi-asserted-by': 'publisher', 'DOI': '10.1002/pbc.29277'}, {'key': 'CIT0024', 'doi-asserted-by': 'publisher', 'DOI': '10.1093/cid/ciab397'}, {'key': 'CIT0025', 'doi-asserted-by': 'publisher', 'DOI': '10.1093/ofid/ofab217'}, { 'key': 'CIT0026', 'doi-asserted-by': 'publisher', 'DOI': '10.1001/jamapediatrics.2020.3988'}, {'key': 'CIT0027', 'doi-asserted-by': 'publisher', 'DOI': '10.1017/S095026882100008X'}, {'key': 'CIT0028', 'doi-asserted-by': 'publisher', 'DOI': '10.1097/INF.0000000000002814'}, {'key': 'CIT0029', 'doi-asserted-by': 'publisher', 'DOI': '10.1056/NEJMsb2104756'}, {'key': 'CIT0030', 'doi-asserted-by': 'publisher', 'DOI': '10.1542/peds.2020-047803'}, {'key': 'CIT0031', 'doi-asserted-by': 'publisher', 'DOI': '10.1007/s00431-020-03876-1'}, { 'key': 'CIT0032', 'unstructured': 'U.S. National Library of Medicine. Study to evaluate the safety, ' 'tolerability, pharmacokinetics, and efficacy of remdesivir (GS-5734TM) ' 'in participants from birth to <18 years of age with Coronavirus Disease ' '2019 (COVID-19) (CARAVAN). ClinicalTrials.gov identifier: NCT04431453. ' '2020. http://clinicaltrials.gov/ct2/show/NCT04431453'}, { 'key': 'CIT0033', 'unstructured': 'Ahmed A, Rojo P, Agwu A, et\xa0al. Remdesivir treatment for COVID-19 in ' 'hospitalized children: CARAVAN interim results. In Conference on ' 'Retroviruses and Opportunistic Infections (CROI) 2022 Annual Meeting; ' '2022. Denver, CO. Abstract 744.'}, {'key': 'CIT0034', 'doi-asserted-by': 'publisher', 'DOI': '10.1097/INF.0000000000003214'}, {'key': 'CIT0035', 'doi-asserted-by': 'publisher', 'DOI': '10.1093/jpids/piab029'}, {'key': 'CIT0036', 'doi-asserted-by': 'publisher', 'DOI': '10.1007/s00431-021-03940-4'}, {'key': 'CIT0037', 'doi-asserted-by': 'publisher', 'DOI': '10.3390/v12121384'}], 'container-title': 'Acta Oncologica', 'original-title': [], 'language': 'en', 'link': [ { 'URL': 'https://www.tandfonline.com/doi/pdf/10.1080/0284186X.2023.2169079', 'content-type': 'unspecified', 'content-version': 'vor', 'intended-application': 'similarity-checking'}], 'deposited': { 'date-parts': [[2023, 4, 3]], 'date-time': '2023-04-03T05:09:15Z', 'timestamp': 1680498555000}, 'score': 1, 'resource': {'primary': {'URL': 'https://www.tandfonline.com/doi/full/10.1080/0284186X.2023.2169079'}}, 'subtitle': [], 'short-title': [], 'issued': {'date-parts': [[2023, 1, 2]]}, 'references-count': 37, 'journal-issue': {'issue': '1', 'published-print': {'date-parts': [[2023, 1, 2]]}}, 'alternative-id': ['10.1080/0284186X.2023.2169079'], 'URL': 'http://dx.doi.org/10.1080/0284186X.2023.2169079', 'relation': {}, 'ISSN': ['0284-186X', '1651-226X'], 'subject': ['Radiology, Nuclear Medicine and imaging', 'Oncology', 'Hematology', 'General Medicine'], 'container-title-short': 'Acta Oncologica', 'published': {'date-parts': [[2023, 1, 2]]}, 'assertion': [ { 'value': 'The publishing and review policy for this title is described in its Aims & ' 'Scope.', 'order': 1, 'name': 'peerreview_statement', 'label': 'Peer Review Statement'}, { 'value': 'http://www.tandfonline.com/action/journalInformation?show=aimsScope&journalCode=ionc20', 'URL': 'http://www.tandfonline.com/action/journalInformation?show=aimsScope&journalCode=ionc20', 'order': 2, 'name': 'aims_and_scope_url', 'label': 'Aim & Scope'}, { 'value': '2022-11-22', 'order': 0, 'name': 'received', 'label': 'Received', 'group': {'name': 'publication_history', 'label': 'Publication History'}}, { 'value': '2023-01-11', 'order': 2, 'name': 'accepted', 'label': 'Accepted', 'group': {'name': 'publication_history', 'label': 'Publication History'}}, { 'value': '2023-01-20', 'order': 3, 'name': 'published', 'label': 'Published', 'group': {'name': 'publication_history', 'label': 'Publication History'}}]}
Loading..
Please send us corrections, updates, or comments. c19early involves the extraction of 100,000+ datapoints from thousands of papers. Community updates help ensure high accuracy. Treatments and other interventions are complementary. All practical, effective, and safe means should be used based on risk/benefit analysis. No treatment or intervention is 100% available and effective for all current and future variants. We do not provide medical advice. Before taking any medication, consult a qualified physician who can provide personalized advice and details of risks and benefits based on your medical history and situation. FLCCC and WCH provide treatment protocols.
  or use drag and drop   
Submit