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Supplementary Data — Montelukast for COVID-19: real-time meta analysis of 8 studies

@CovidAnalysis, July 2024, Version 8V8
 
0 0.25 0.5 0.75 1 1.25 1.5 1.75 2+ Excluded Lima-Morales 78% 0.22 [0.12-0.41] death 15/481 52/287 CT​1 Improvement, RR [CI] Treatment Control Excluded Lima-Morales 52% 0.48 [0.20-1.18] ventilation 8/434 11/287 CT​1 Excluded Lima-Morales 67% 0.33 [0.22-0.47] hosp. 44/481 89/287 CT​1 Excluded Lima-Morales 59% 0.41 [0.30-0.55] no recov. 75/481 118/287 CT​1 Khan 64% 0.36 [0.10-1.03] progression 3/30 20/62 Khan 12% 0.88 [0.67-1.14] hosp. time 30 (n) 62 (n) Kumar (DB RCT) 67% 0.33 [0.04-3.09] ICU 1/45 3/45 Kumar (DB RCT) -25% 1.25 [0.54-2.87] progression 10/45 8/45 Kumar (DB RCT) 0% 1.00 [0.64-1.56] no disch. 21/45 21/45 Kerget (RCT) 92% 0.08 [0.01-0.56] death 0/120 4/60 Kerget (RCT) 89% 0.11 [0.01-2.02] death 0/60 4/60 Kerget (RCT) 89% 0.11 [0.01-2.02] death 0/60 4/60 Kerget (RCT) 81% 0.19 [0.05-0.68] progression 3/120 8/60 Kerget (RCT) 88% 0.12 [0.02-0.97] progression 1/60 8/60 Kerget (RCT) 75% 0.25 [0.06-1.13] progression 2/60 8/60 Kerget (RCT) 15% 0.85 [0.72-0.99] hosp. time 60 (n) 60 (n) Kerget (RCT) 15% 0.85 [0.74-0.99] hosp. time 60 (n) 60 (n) Soltani (RCT) 20% 0.80 [0.67-0.95] hosp. time 51 (n) 76 (n) Soltani (RCT) 25% 0.75 [0.64-0.88] no recov. 51 (n) 76 (n) Soltani (RCT) 21% 0.79 [0.62-1.02] no recov. 51 (n) 76 (n) Mohamed H.. (RCT) 50% 0.50 [0.41-0.61] recov. time 32 (n) 36 (n) post-COVID cough Mohamed H.. (RCT) 70% 0.30 [0.22-0.41] recov. time 32 (n) 36 (n) post-COVID cough Mohamed H.. (RCT) 82% 0.18 [0.11-0.30] recov. time 32 (n) 36 (n) post-COVID cough Mohamed H.. (RCT) 80% 0.20 [0.12-0.32] recov. time 32 (n) 36 (n) post-COVID cough Mohamed H.. (RCT) 82% 0.18 [0.11-0.30] recov. time 32 (n) 36 (n) post-COVID cough ACTIV-6 Rothman (DB RCT) 1% 0.99 [0.14-7.01] hosp. 2/628 2/622 ACTIV-6 Rothman (DB RCT) 1% 0.99 [0.52-1.89] hosp./ER 18/628 18/622 ACTIV-6 Rothman (DB RCT) 32% 0.68 [0.34-3.03] progression n/a n/a ACTIV-6 Rothman (DB RCT) -41% 1.41 [0.67-6.25] progression n/a n/a ACTIV-6 Rothman (DB RCT) 24% 0.76 [0.44-2.00] progression n/a n/a ACTIV-6 Rothman (DB RCT) 2% 0.98 [0.89-1.09] no recov. 628 (n) 622 (n) ACTIV-6 Rothman (DB RCT) 2% 0.98 [0.96-1.00] recov. time 628 (n) 622 (n) Bozek 91% 0.09 [0.01-0.80] hosp. 1/327 4/118 Bozek 82% 0.18 [0.06-0.59] cases 4/327 8/118 Alhmoud 13% 0.87 [0.52-1.47] hosp. 111 (n) 505 (n) Montelukast COVID-19 outcomes c19early.org July 2024 1 CT: study uses combined treatment Favors montelukast Favors control
Figure S1. All outcomes.
Please send us corrections, updates, or comments. c19early involves the extraction of 100,000+ datapoints from thousands of papers. Community updates help ensure high accuracy. Treatments and other interventions are complementary. All practical, effective, and safe means should be used based on risk/benefit analysis. No treatment or intervention is 100% available and effective for all current and future variants. We do not provide medical advice. Before taking any medication, consult a qualified physician who can provide personalized advice and details of risks and benefits based on your medical history and situation. FLCCC and WCH provide treatment protocols.
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