Analgesics
Antiandrogens
Antihistamines
Azvudine
Bromhexine
Budesonide
Colchicine
Conv. Plasma
Curcumin
Famotidine
Favipiravir
Fluvoxamine
Hydroxychlor..
Ivermectin
Lifestyle
Melatonin
Metformin
Minerals
Molnupiravir
Monoclonals
Naso/orophar..
Nigella Sativa
Nitazoxanide
PPIs
Paxlovid
Quercetin
Remdesivir
Thermotherapy
Vitamins
More

Other
Feedback
Home
 
next
study
previous
study
c19early.org COVID-19 treatment researchAntiandrogensAntiandrogens (more..)
Melatonin Meta
Metformin Meta
Antihistamines Meta
Azvudine Meta Molnupiravir Meta
Bromhexine Meta
Budesonide Meta
Colchicine Meta Nigella Sativa Meta
Conv. Plasma Meta Nitazoxanide Meta
Curcumin Meta PPIs Meta
Famotidine Meta Paxlovid Meta
Favipiravir Meta Quercetin Meta
Fluvoxamine Meta Remdesivir Meta
Hydroxychlor.. Meta Thermotherapy Meta
Ivermectin Meta

All Studies   Meta Analysis       

Androgen Deprivation Therapy in Men with Prostate Cancer Does Not Affect Risk of Infection with SARS-CoV-2

Klein et al., Journal of Urology, doi:10.1097/JU.0000000000001338
Feb 2021  
  Post
  Facebook
Share
  Source   PDF   All Studies   Meta AnalysisMeta
Mortality -124% Improvement Relative Risk Case 7% Antiandrogens for COVID-19  Klein et al.  Prophylaxis Is prophylaxis with antiandrogens beneficial for COVID-19? Retrospective 1,779 patients in the USA (March - June 2020) Higher mortality with antiandrogens (not stat. sig., p=0.12) c19early.org Klein et al., J. Urology, February 2021 Favorsvarious Favorscontrol 0 0.5 1 1.5 2+
7th treatment shown to reduce risk in September 2020, now with p = 0.000000056 from 49 studies.
No treatment is 100% effective. Protocols combine treatments.
5,100+ studies for 111 treatments. c19early.org
Retrospective 1,779 prostate cancer patients, showing no significant differences in COVID-19 outcomes with ADT.
risk of death, 123.9% higher, RR 2.24, p = 0.12, treatment 6 of 304 (2.0%), control 13 of 1,475 (0.9%).
risk of case, 6.6% lower, RR 0.93, p = 0.80, treatment 17 of 304 (5.6%), control 85 of 1,475 (5.8%), NNT 586, adjusted per study, odds ratio converted to relative risk, multivariable.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Klein et al., 1 Feb 2021, retrospective, USA, peer-reviewed, 7 authors, study period 12 March, 2020 - 10 June, 2020.
This PaperAntiandrogensAll
{ 'indexed': {'date-parts': [[2022, 3, 25]], 'date-time': '2022-03-25T19:28:38Z', 'timestamp': 1648236518979}, 'reference-count': 0, 'publisher': 'Ovid Technologies (Wolters Kluwer Health)', 'issue': '2', 'content-domain': {'domain': [], 'crossmark-restriction': False}, 'short-container-title': ['Journal of Urology'], 'published-print': {'date-parts': [[2021, 2]]}, 'DOI': '10.1097/ju.0000000000001338', 'type': 'journal-article', 'created': {'date-parts': [[2020, 9, 8]], 'date-time': '2020-09-08T20:09:40Z', 'timestamp': 1599595780000}, 'page': '441-443', 'source': 'Crossref', 'is-referenced-by-count': 19, 'title': [ 'Androgen Deprivation Therapy in Men with Prostate Cancer Does Not Affect Risk of Infection ' 'with SARS-CoV-2'], 'prefix': '10.1097', 'volume': '205', 'author': [ { 'given': 'Eric A.', 'family': 'Klein', 'sequence': 'first', 'affiliation': [ { 'name': 'Department of Urology, Glickman Urological and Kidney Institute, ' 'Cleveland, Ohio'}]}, { 'given': 'Jianbo', 'family': 'Li', 'sequence': 'additional', 'affiliation': [ { 'name': 'Department of Quantitative Health Sciences, Lerner Research ' 'Institute, Cleveland, Ohio'}]}, { 'given': 'Alex', 'family': 'Milinovich', 'sequence': 'additional', 'affiliation': [ { 'name': 'Department of Quantitative Health Sciences, Lerner Research ' 'Institute, Cleveland, Ohio'}]}, { 'given': 'Jesse D.', 'family': 'Schold', 'sequence': 'additional', 'affiliation': [ { 'name': 'Department of Quantitative Health Sciences, Lerner Research ' 'Institute, Cleveland, Ohio'}]}, { 'given': 'Nima', 'family': 'Sharifi', 'sequence': 'additional', 'affiliation': [ { 'name': 'Department of Cancer Biology and Genitourinary Malignancies ' 'Research Center,Lerner Research Institute, Cleveland, Ohio'}]}, { 'given': 'Michael W.', 'family': 'Kattan', 'sequence': 'additional', 'affiliation': [ { 'name': 'Department of Quantitative Health Sciences, Lerner Research ' 'Institute, Cleveland, Ohio'}]}, { 'given': 'Lara', 'family': 'Jehi', 'sequence': 'additional', 'affiliation': [ { 'name': 'Department of Neurology, Neurological Institute Cleveland Clinic ' 'and Cleveland Clinic Lerner College of Medicine, Cleveland, ' 'Ohio'}]}], 'member': '276', 'container-title': ['Journal of Urology'], 'original-title': [], 'language': 'en', 'deposited': { 'date-parts': [[2022, 3, 25]], 'date-time': '2022-03-25T00:27:05Z', 'timestamp': 1648168025000}, 'score': 1, 'resource': {'primary': {'URL': 'http://www.jurology.com/doi/10.1097/JU.0000000000001338'}}, 'subtitle': [], 'short-title': [], 'issued': {'date-parts': [[2021, 2]]}, 'references-count': 0, 'journal-issue': {'issue': '2', 'published-print': {'date-parts': [[2021, 2]]}}, 'alternative-id': ['10.1097/JU.0000000000001338'], 'URL': 'http://dx.doi.org/10.1097/ju.0000000000001338', 'relation': {}, 'ISSN': ['0022-5347', '1527-3792'], 'issn-type': [{'value': '0022-5347', 'type': 'print'}, {'value': '1527-3792', 'type': 'electronic'}], 'subject': ['Urology'], 'published': {'date-parts': [[2021, 2]]}}
Loading..
Please send us corrections, updates, or comments. c19early involves the extraction of 100,000+ datapoints from thousands of papers. Community updates help ensure high accuracy. Treatments and other interventions are complementary. All practical, effective, and safe means should be used based on risk/benefit analysis. No treatment or intervention is 100% available and effective for all current and future variants. We do not provide medical advice. Before taking any medication, consult a qualified physician who can provide personalized advice and details of risks and benefits based on your medical history and situation. FLCCC and WCH provide treatment protocols.
  or use drag and drop   
Submit