Abstract: Journal Pre-proof
Real-world evidence of sotrovimab effectiveness for preventing
severe outcomes in patients with COVID-19: A quality improvement
propensity matched retrospective cohort study of a pan-provincial
program in Alberta, Canada
Gregory Farmer , Khokan C. Sikdar , TKT Lo , John Conly ,
Jeremy Slobodan , Jordan Ross , Samantha James ,
Hussain Usman , Kyle Kemp , Kristi Baker , Karen Doucette ,
Cheri Nijssen-Jordan , Lynora M. Saxinger , A. Mark Joffe
PII:
DOI:
Reference:
S1201-9712(24)00207-8
https://doi.org/10.1016/j.ijid.2024.107136
IJID 107136
To appear in:
International Journal of Infectious Diseases
Received date:
Revised date:
Accepted date:
11 January 2024
21 May 2024
11 June 2024
Please cite this article as: Gregory Farmer , Khokan C. Sikdar , TKT Lo , John Conly ,
Jeremy Slobodan , Jordan Ross , Samantha James , Hussain Usman , Kyle Kemp , Kristi Baker ,
Karen Doucette , Cheri Nijssen-Jordan , Lynora M. Saxinger , A. Mark Joffe , Real-world evidence of sotrovimab effectiveness for preventing severe outcomes in patients with COVID19: A quality improvement propensity matched retrospective cohort study of a pan-provincial
program in Alberta, Canada, International Journal of Infectious Diseases (2024), doi:
https://doi.org/10.1016/j.ijid.2024.107136
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© 2024 Published by Elsevier Ltd on behalf of International Society for Infectious Diseases.
This is an open access article under the CC BY-NC-ND license
(http://creativecommons.org/licenses/by-nc-nd/4.0/)
Highlights:
Post-marketing surveillance of sotrovimab in Canada is limited.
Sotrovimab was not associated with improved outcomes.
Study results were consistent across different analytic methodologies.
Study findings need to be confirmed in other Canadian provinces.
Sotrovimab effectiveness
Title: Real-world evidence of sotrovimab effectiveness for preventing severe outcomes in
patients with COVID-19: A quality improvement propensity matched retrospective cohort study
of a pan-provincial program in Alberta, Canada
Authors: Gregory Farmer, MSc1; Khokan C. Sikdar, PhD1,5; TKT Lo, PhD1; John Conly, MD,
DSc2,8; Jeremy Slobodan, BSP3; Jordan Ross, MPH1; Samantha James, MPH1; Hussain Usman,
M.B.B.S, MSc, Dr.PH1; Kyle Kemp, PhD1; Kristi Baker, PhD4; Karen Doucette, MD, MSc6,8;
Cheri Nijssen-Jordan, MD, MBA7; Lynora, M. Saxinger, MD6,8; A. Mark Joffe, MD6,8.
Author affiliations: 1Department of Provincial Population and Public Health (PPPH), Alberta
Health Services, Edmonton, Canada; 2 Department of Medicine, Division of Infectious Diseases,
Cumming School of Medicine, University of Calgary, Calgary, Canada; 3Department of Drug
Utilization, Information and Stewardship, Alberta Health Services, Edmonton, Canada;
4
Department of Oncology, Division of Experimental Oncology, University of Alberta, Edmonton,
Canada; 5Department of Community Health Sciences, Cumming School of Medicine, University
of..
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