Can povidone Iodine gargle/mouthrinse inactivate SARS-CoV-2 and decrease the risk of nosocomial and community transmission during the COVID-19 pandemic? An evidence-based update

DOI record: { "DOI": "10.1016/j.jdsr.2021.03.001", "ISSN": [ "1882-7616" ], "URL": "http://dx.doi.org/10.1016/j.jdsr.2021.03.001", "alternative-id": [ "S1882761621000065" ], "assertion": [ { "label": "This article is maintained by", "name": "publisher", "value": "Elsevier" }, { "label": "Article Title", "name": "articletitle", "value": "Can povidone iodine gargle/mouthrinse inactivate SARS-CoV-2 and decrease the risk of nosocomial and community transmission during the COVID-19 pandemic? An evidence-based update" }, { "label": "Journal Title", "name": "journaltitle", "value": "Japanese Dental Science Review" }, { "label": "CrossRef DOI link to publisher maintained version", "name": "articlelink", "value": "https://doi.org/10.1016/j.jdsr.2021.03.001" }, { "label": "Content Type", "name": "content_type", "value": "article" }, { "label": "Copyright", "name": "copyright" } ], "author": [ { "affiliation": [], "family": "Chopra", "given": "Aditi", "sequence": "first" }, { "affiliation": [], "family": "Sivaraman", "given": "Karthik", "sequence": "additional" }, { "affiliation": [], "family": "Radhakrishnan", "given": "Raghu", "sequence": "additional" }, { "affiliation": [], "family": "Balakrishnan", "given": "Dhanasekar", "sequence": "additional" }, { "affiliation": [], "family": "Narayana", "given": "Aparna", "sequence": "additional" } ], "container-title": "Japanese Dental Science Review", "container-title-short": "Japanese Dental Science Review", "content-domain": { "crossmark-restriction": true, "domain": [ "elsevier.com", "sciencedirect.com" ] }, "created": { "date-parts": [ [ 2021, 3, 18 ] ], "date-time": "2021-03-18T20:46:56Z", "timestamp": 1616100416000 }, "deposited": { "date-parts": [ [ 2023, 10, 23 ] ], "date-time": "2023-10-23T11:49:26Z", "timestamp": 1698061766000 }, "indexed": { "date-parts": [ [ 2024, 5, 1 ] ], "date-time": "2024-05-01T14:31:23Z", "timestamp": 1714573883718 }, "is-referenced-by-count": 27, "issued": { "date-parts": [ [ 2021, 11 ] ] }, "language": "en", "license": [ { "URL": "https://www.elsevier.com/tdm/userlicense/1.0/", "content-version": "tdm", "delay-in-days": 0, "start": { "date-parts": [ [ 2021, 11, 1 ] ], "date-time": "2021-11-01T00:00:00Z", "timestamp": 1635724800000 } }, { "URL": "http://creativecommons.org/licenses/by-nc-nd/4.0/", "content-version": "vor", "delay-in-days": 0, "start": { "date-parts": [ [ 2021, 3, 15 ] ], "date-time": "2021-03-15T00:00:00Z", "timestamp": 1615766400000 } } ], "link": [ { "URL": "https://api.elsevier.com/content/article/PII:S1882761621000065?httpAccept=text/xml", "content-type": "text/xml", "content-version": "vor", "intended-application": "text-mining" }, { "URL": "https://api.elsevier.com/content/article/PII:S1882761621000065?httpAccept=text/plain", "content-type": "text/plain", "content-version": "vor", "intended-application": "text-mining" } ], "member": "78", "original-title": [], "page": "39-45", "prefix": "10.1016", "published": { "date-parts": [ [ 2021, 11 ] ] }, "published-print": { "date-parts": [ [ 2021, 11 ] ] }, "publisher": "Elsevier BV", "reference": [ { "DOI": "10.1001/jama.2020.1097", "article-title": "The novel coronavirus originating in Wuhan, China: challenges for Global Health Governance", "author": "Phelan", "doi-asserted-by": "crossref", "first-page": "709", "issue": "8", "journal-title": "JAMA", "key": "10.1016/j.jdsr.2021.03.001_bib0005", "volume": "323", "year": "2020" }, { "DOI": "10.1016/S0140-6736(20)30154-9", "article-title": "A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: a study of a family cluster", "author": "Chan", "doi-asserted-by": "crossref", "first-page": "514", "journal-title": "Lancet (London, England)", "key": "10.1016/j.jdsr.2021.03.001_bib0010", "volume": "395", "year": "2020" }, { "DOI": "10.3201/eid2606.200239", "article-title": "Community transmission of severe acute respiratory syndrome coronavirus 2, Shenzhen, China, 2020", "author": "Liu", "doi-asserted-by": "crossref", "journal-title": "Emerg Infect Dis", "key": "10.1016/j.jdsr.2021.03.001_bib0015", "volume": "26", "year": "2020" }, { "article-title": "Interpretation of policies for group standards and the practice of group standardizations in Chinese Preventive Medicine Association", "author": "Feng", "first-page": "371", "issue": "4", "journal-title": "Zhonghua Liu Xing Bing Xue Za Zhi", "key": "10.1016/j.jdsr.2021.03.001_bib0020", "volume": "40", "year": "2019" }, { "DOI": "10.1080/01652176.2020.1727993", "article-title": "Emerging novel coronavirus (2019-nCoV)-current scenario, evolutionary perspective based on genome analysis and recent developments", "author": "Malik", "doi-asserted-by": "crossref", "first-page": "68", "journal-title": "Vet Q", "key": "10.1016/j.jdsr.2021.03.001_bib0025", "volume": "40", "year": "2020" }, { "DOI": "10.1038/s41591-020-0820-9", "article-title": "The proximal origin of SARS-CoV-2", "author": "Andersen", "doi-asserted-by": "crossref", "first-page": "450", "journal-title": "Nat Med", "key": "10.1016/j.jdsr.2021.03.001_bib0030", "volume": "26", "year": "2020" }, { "DOI": "10.1001/jama.2020.1490", "article-title": "2019 novel coronavirus-important information for clinicians", "author": "Del Rio", "doi-asserted-by": "crossref", "first-page": "1039", "issue": "11", "journal-title": "JAMA", "key": "10.1016/j.jdsr.2021.03.001_bib0035", "volume": "323", "year": "2020" }, { "DOI": "10.1002/jmv.23698", "article-title": "Respiratory virus RNA is detectable in airborne and droplet particles", "author": "Gralton", "doi-asserted-by": "crossref", "first-page": "2151", "journal-title": "J Med Virol", "key": "10.1016/j.jdsr.2021.03.001_bib0040", "volume": "85", "year": "2013" }, { "DOI": "10.1056/NEJMoa2001191", "article-title": "First case of 2019 novel coronavirus in the United States", "author": "Holshue", "doi-asserted-by": "crossref", "first-page": "929", "journal-title": "N Engl J Med", "key": "10.1016/j.jdsr.2021.03.001_bib0045", "volume": "382", "year": "2020" }, { "DOI": "10.1007/s40121-019-00260-x", "article-title": "Infectious disease management and control with povidone iodine", "author": "Eggers", "doi-asserted-by": "crossref", "first-page": "581", "journal-title": "Infect Dis Ther", "key": "10.1016/j.jdsr.2021.03.001_bib0050", "volume": "8", "year": "2019" }, { "DOI": "10.2139/ssrn.3563092", "article-title": "The use of povidone iodine nasal spray and mouthwash during the current COVID-19 pandemic may protect healthcare workers and reduce cross infection", "author": "Kirk-Bayley", "doi-asserted-by": "crossref", "journal-title": "SSRN Electron J", "key": "10.1016/j.jdsr.2021.03.001_bib0055", "year": "2020" }, { "DOI": "10.1902/jop.2006.060010", "article-title": "Systematic review of the association between respiratory diseases and oral health", "author": "Azarpazhooh", "doi-asserted-by": "crossref", "first-page": "1465", "journal-title": "J Periodontol", "key": "10.1016/j.jdsr.2021.03.001_bib0060", "volume": "77", "year": "2006" }, { "article-title": "Efficacy of povidone-iodine nasal and oral antiseptic preparations against severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2)", "author": "Pelletier", "journal-title": "Ear Nose Throat J", "key": "10.1016/j.jdsr.2021.03.001_bib0065", "year": "2020" }, { "DOI": "10.1213/ANE.0000000000004829", "article-title": "Perioperative COVID-19 defense: an evidence-based approach for optimization of infection control and operating room management", "author": "Dexter", "doi-asserted-by": "crossref", "first-page": "37", "journal-title": "Anesth Analg", "key": "10.1016/j.jdsr.2021.03.001_bib0070", "volume": "131", "year": "2020" }, { "article-title": "SARS-CoV-2 viral inactivation using low dose povidone-iodine oral rinse – immediate application for the prosthodontic practice", "author": "Tessema", "first-page": "204", "journal-title": "J Prosthodont", "key": "10.1016/j.jdsr.2021.03.001_bib0075", "year": "2020" }, { "DOI": "10.1002/hed.26200", "article-title": "Topical preparations to reduce SARS-CoV-2 aerosolization in head and neck mucosal surgery", "author": "Parhar", "doi-asserted-by": "crossref", "first-page": "1268", "journal-title": "Head Neck", "key": "10.1016/j.jdsr.2021.03.001_bib0080", "volume": "42", "year": "2020" }, { "DOI": "10.1111/jopr.13209", "article-title": "Rapid in-vitro inactivation of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) using povidone-iodine oral antiseptic rinse", "author": "Bidra", "doi-asserted-by": "crossref", "first-page": "529", "journal-title": "J Prosthodont", "key": "10.1016/j.jdsr.2021.03.001_bib0085", "volume": "29", "year": "2020" }, { "DOI": "10.1111/jopr.13220", "article-title": "Comparison of in vitro inactivation of SARS CoV-2 with hydrogen peroxide and povidone-iodine oral antiseptic rinses", "author": "Bidra", "doi-asserted-by": "crossref", "first-page": "599", "journal-title": "J Prosthodont", "key": "10.1016/j.jdsr.2021.03.001_bib0090", "volume": "29", "year": "2020" }, { "DOI": "10.1093/infdis/jiaa471", "article-title": "Virucidal efficacy of different oral rinses against severe acute respiratory syndrome coronavirus 2", "author": "Meister", "doi-asserted-by": "crossref", "first-page": "1289", "issue": "8", "journal-title": "J Infect Dis", "key": "10.1016/j.jdsr.2021.03.001_bib0095", "volume": "222", "year": "2020" }, { "DOI": "10.1016/j.tripleo.2004.06.005", "article-title": "The role of oral microbial colonization in ventilator-associated pneumonia", "author": "Brennan", "doi-asserted-by": "crossref", "first-page": "665", "journal-title": "Oral Surg Oral Med Oral Pathol Oral Radiol Endod", "key": "10.1016/j.jdsr.2021.03.001_bib0100", "volume": "98", "year": "2004" }, { "DOI": "10.1159/000246032", "article-title": "Povidone-iodine to prevent mucositis in patients during antineoplastic radiochemotherapy", "author": "Rahn", "doi-asserted-by": "crossref", "first-page": "57", "issue": "2", "journal-title": "Dermatology", "key": "10.1016/j.jdsr.2021.03.001_bib0105", "volume": "195", "year": "1997" }, { "DOI": "10.1177/0145561320932318", "article-title": "Povidone-iodine use in sinonasal and oral cavities: a review of safety in the COVID-19 era", "author": "Frank", "doi-asserted-by": "crossref", "first-page": "586", "issue": "9", "journal-title": "Ear Nose Throat J", "key": "10.1016/j.jdsr.2021.03.001_bib0110", "volume": "99", "year": "2020" }, { "DOI": "10.1111/j.1601-0825.2007.01410a.x", "article-title": "Oral biofilms, periodontitis, and pulmonary infections", "author": "Paju", "doi-asserted-by": "crossref", "first-page": "508", "journal-title": "Oral Dis", "key": "10.1016/j.jdsr.2021.03.001_bib0115", "volume": "13", "year": "2007" }, { "DOI": "10.1038/sj.bdj.2017.315", "article-title": "Evidence summary: the relationship between oral health and pulmonary disease", "author": "Manger", "doi-asserted-by": "crossref", "first-page": "527", "journal-title": "Br Dent J", "key": "10.1016/j.jdsr.2021.03.001_bib0120", "volume": "222", "year": "2017" }, { "article-title": "Oral hygiene care for critically ill patients to prevent ventilator-associated pneumonia", "author": "Hua", "first-page": "CD008367", "journal-title": "Cochrane Database Syst Rev", "key": "10.1016/j.jdsr.2021.03.001_bib0125", "volume": "10", "year": "2016" }, { "DOI": "10.11124/JBISRIR-2016-003047", "article-title": "Oral hygiene in patients with chronic obstructive pulmonary disease: a scoping review protocol", "author": "Pedersen", "doi-asserted-by": "crossref", "first-page": "1236", "journal-title": "JBI Database Syst Rev Implement Rep", "key": "10.1016/j.jdsr.2021.03.001_bib0130", "volume": "15", "year": "2017" }, { "article-title": "Oral care measures for preventing nursing home-acquired pneumonia", "author": "Liu", "first-page": "CD012416", "journal-title": "Cochrane Database Syst Rev", "key": "10.1016/j.jdsr.2021.03.001_bib0135", "volume": "9", "year": "2018" }, { "DOI": "10.1038/s41368-020-0075-9", "article-title": "Transmission routes of 2019-nCoV and controls in dental practice", "author": "Peng", "doi-asserted-by": "crossref", "first-page": "9", "journal-title": "Int J Oral Sci", "key": "10.1016/j.jdsr.2021.03.001_bib0140", "volume": "12", "year": "2020" }, { "DOI": "10.1093/cid/ciaa149", "article-title": "Consistent detection of 2019 novel coronavirus in saliva", "author": "To", "doi-asserted-by": "crossref", "journal-title": "Clin Infect Dis", "key": "10.1016/j.jdsr.2021.03.001_bib0145", "year": "2020" }, { "DOI": "10.1002/jmv.25707", "article-title": "Potential interventions for novel coronavirus in China: a systematic review", "author": "Zhang", "doi-asserted-by": "crossref", "first-page": "479", "journal-title": "J Med Virol", "key": "10.1016/j.jdsr.2021.03.001_bib0150", "volume": "92", "year": "2020" }, { "DOI": "10.1038/s41368-020-0080-z", "article-title": "Saliva: potential diagnostic value and transmission of 2019-nCoV", "author": "Xu", "doi-asserted-by": "crossref", "first-page": "11", "journal-title": "Int J Oral Sci", "key": "10.1016/j.jdsr.2021.03.001_bib0155", "volume": "12", "year": "2020" }, { "DOI": "10.1016/j.cell.2020.02.052", "article-title": "SARS-cov-2 cell entry depends on ACE2 and TMPRSS2 and is blocked by a clinically proven protease inhibitor", "author": "Hoffmann", "doi-asserted-by": "crossref", "journal-title": "Cell", "key": "10.1016/j.jdsr.2021.03.001_bib0160", "volume": "181", "year": "2020" }, { "DOI": "10.14219/jada.archive.2004.0019", "article-title": "Guidelines for infection control in dental health care settings – 2003", "author": "Kohn", "doi-asserted-by": "crossref", "first-page": "33", "journal-title": "J Am Dent Assoc", "key": "10.1016/j.jdsr.2021.03.001_bib0165", "volume": "135", "year": "2004" }, { "DOI": "10.1016/j.jhin.2006.05.022", "article-title": "Factors involved in the aerosol transmission of infection and control of ventilation in healthcare premises", "author": "Tang", "doi-asserted-by": "crossref", "first-page": "100", "journal-title": "J Hosp Infect", "key": "10.1016/j.jdsr.2021.03.001_bib0170", "volume": "64", "year": "2006" }, { "DOI": "10.1016/S0196-6553(98)70046-X", "article-title": "Characterization of infectious aerosols in health care facilities: an aid to effective engineering controls and preventive strategies", "author": "Cole", "doi-asserted-by": "crossref", "first-page": "453", "journal-title": "Am J Infect Control", "key": "10.1016/j.jdsr.2021.03.001_bib0175", "volume": "26", "year": "1998" }, { "DOI": "10.1073/pnas.0408159101", "article-title": "Inhaling to mitigate exhaled bioaerosols", "author": "Edwards", "doi-asserted-by": "crossref", "first-page": "17383", "journal-title": "Proc Natl Acad Sci U S A", "key": "10.1016/j.jdsr.2021.03.001_bib0180", "volume": "101", "year": "2004" }, { "DOI": "10.1016/S0140-6736(20)30183-5", "article-title": "Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China", "author": "Huang", "doi-asserted-by": "crossref", "first-page": "497", "journal-title": "Lancet (London, England)", "key": "10.1016/j.jdsr.2021.03.001_bib0185", "volume": "395", "year": "2020" }, { "DOI": "10.1001/jama.2020.1585", "article-title": "Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan, China", "author": "Wang", "doi-asserted-by": "crossref", "first-page": "1061", "issue": "11", "journal-title": "JAMA", "key": "10.1016/j.jdsr.2021.03.001_bib0190", "volume": "323", "year": "2020" }, { "DOI": "10.1001/jama.2020.2648", "article-title": "Characteristics of and important lessons from the coronavirus disease 2019 (COVID-19) outbreak in China: summary of a report of 72 314 cases from the Chinese Center for Disease Control and Prevention", "author": "Wu", "doi-asserted-by": "crossref", "first-page": "1239", "issue": "13", "journal-title": "JAMA", "key": "10.1016/j.jdsr.2021.03.001_bib0195", "volume": "323", "year": "2020" }, { "DOI": "10.1056/NEJMc2001468", "article-title": "Transmission of 2019-nCoV infection from an asymptomatic contact in Germany", "author": "Rothe", "doi-asserted-by": "crossref", "first-page": "970", "journal-title": "N Engl J Med", "key": "10.1016/j.jdsr.2021.03.001_bib0200", "volume": "382", "year": "2020" }, { "DOI": "10.2807/1560-7917.ES.2020.25.5.2000062", "article-title": "Incubation period of 2019 novel coronavirus (2019-nCoV) infections among travelers from Wuhan, China, 20–28 January 2020", "author": "Backer", "doi-asserted-by": "crossref", "first-page": "2000062", "issue": "5", "journal-title": "Euro Surveill", "key": "10.1016/j.jdsr.2021.03.001_bib0205", "volume": "25", "year": "2020" }, { "DOI": "10.1001/jamapediatrics.2020.1467", "article-title": "Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection in children and adolescents: a systematic review", "author": "Castagnoli", "doi-asserted-by": "crossref", "first-page": "882", "issue": "9", "journal-title": "JAMA Pediatr", "key": "10.1016/j.jdsr.2021.03.001_bib0210", "volume": "174", "year": "2020" }, { "DOI": "10.1902/jop.2001.72.1.50", "article-title": "Potential associations between chronic respiratory disease and periodontal disease: analysis of National Health and Nutrition Examination Survey III", "author": "Scannapieco", "doi-asserted-by": "crossref", "first-page": "50", "journal-title": "J Periodontol", "key": "10.1016/j.jdsr.2021.03.001_bib0215", "volume": "72", "year": "2001" }, { "DOI": "10.1111/j.1741-2358.2012.00637.x", "article-title": "Oral health care and aspiration pneumonia in frail older people: a systematic literature review", "author": "van der Maarel-Wierink", "doi-asserted-by": "crossref", "first-page": "3", "journal-title": "Gerodontology", "key": "10.1016/j.jdsr.2021.03.001_bib0220", "volume": "30", "year": "2013" }, { "DOI": "10.1056/NEJMc2001737", "article-title": "SARS-CoV-2 viral load in upper respiratory specimens of infected patients", "author": "Zou", "doi-asserted-by": "crossref", "first-page": "1177", "journal-title": "N Engl J Med", "key": "10.1016/j.jdsr.2021.03.001_bib0225", "volume": "382", "year": "2020" }, { "article-title": "Effect of povidone-iodine on herpesvirus type 2, in vitro", "author": "Amstey", "first-page": "528", "journal-title": "Obstet Gynecol", "key": "10.1016/j.jdsr.2021.03.001_bib0230", "volume": "46", "year": "1975" }, { "DOI": "10.1159/000246027", "article-title": "Inactivation of human viruses by povidone-iodine in comparison with other antiseptics", "author": "Kawana", "doi-asserted-by": "crossref", "first-page": "29", "issue": "Suppl", "journal-title": "Dermatology", "key": "10.1016/j.jdsr.2021.03.001_bib0235", "volume": "195", "year": "1997" }, { "DOI": "10.1111/ijcp.12707", "article-title": "Practical use of povidone-iodine antiseptic in the maintenance of oral health and in the prevention and treatment of common oropharyngeal infections", "author": "Kanagalingam", "doi-asserted-by": "crossref", "first-page": "1247", "journal-title": "Int J Clin Pract", "key": "10.1016/j.jdsr.2021.03.001_bib0240", "volume": "69", "year": "2015" }, { "DOI": "10.1159/000246043", "article-title": "Molecular effects of povidone-iodine on relevant microorganisms: an electron-microscopic and biochemical study", "author": "Schreier", "doi-asserted-by": "crossref", "first-page": "111", "issue": "Suppl", "journal-title": "Dermatology", "key": "10.1016/j.jdsr.2021.03.001_bib0245", "volume": "195", "year": "1997" }, { "DOI": "10.1016/j.burns.2007.11.014", "article-title": "Anti-inflammatory properties of a liposomal hydrogel with povidone-iodine (Repithel) for wound healing in vitro", "author": "Beukelman", "doi-asserted-by": "crossref", "first-page": "845", "journal-title": "Burns", "key": "10.1016/j.jdsr.2021.03.001_bib0250", "volume": "34", "year": "2008" }, { "DOI": "10.1016/S0166-3542(01)00213-3", "article-title": "Virucidal activity and cytotoxicity of the liposomal formulation of povidone-iodine", "author": "Wutzler", "doi-asserted-by": "crossref", "first-page": "89", "journal-title": "Antiviral Res", "key": "10.1016/j.jdsr.2021.03.001_bib0255", "volume": "54", "year": "2002" }, { "DOI": "10.1186/1743-422X-6-124", "article-title": "Mechanisms of the action of povidone-iodine against human and avian influenza A viruses: its effects on hemagglutination and sialidase activities", "author": "Sriwilaijaroen", "doi-asserted-by": "crossref", "first-page": "124", "journal-title": "Virol J", "key": "10.1016/j.jdsr.2021.03.001_bib0260", "volume": "6", "year": "2009" }, { "DOI": "10.1093/function/zqaa002", "article-title": "Potential role of oral rinses targeting the viral lipid envelope in SARS-CoV-2 infection", "author": "O’Donnell", "doi-asserted-by": "crossref", "first-page": "zqaa002", "issue": "1", "journal-title": "Function (Oxf)", "key": "10.1016/j.jdsr.2021.03.001_bib0265", "volume": "1", "year": "2020" }, { "article-title": "Prevention of hospital-acquired pneumonia (strategies for prevention of hospital-acquired infections)", "author": "Anon", "first-page": "S48", "issue": "Suppl. 1", "journal-title": "Respirology", "key": "10.1016/j.jdsr.2021.03.001_bib0270", "volume": "9", "year": "2004" }, { "DOI": "10.1159/000089210", "article-title": "Outbreak of highly pathogenic avian influenza in Japan and anti-influenza virus activity of povidone-iodine products", "author": "Ito", "doi-asserted-by": "crossref", "first-page": "115", "issue": "Suppl", "journal-title": "Dermatology", "key": "10.1016/j.jdsr.2021.03.001_bib0275", "volume": "212", "year": "2006" }, { "article-title": "Inactivation of SARS coronavirus by means of povidone-iodine, physical conditions, and chemical reagents", "author": "Kariwa", "first-page": "105", "journal-title": "Jpn J Vet Res", "key": "10.1016/j.jdsr.2021.03.001_bib0280", "volume": "52", "year": "2004" }, { "DOI": "10.1159/000089211", "article-title": "Inactivation of SARS coronavirus by means of povidone-iodine, physical conditions and chemical reagents", "author": "Kariwa", "doi-asserted-by": "crossref", "first-page": "119", "issue": "Suppl", "journal-title": "Dermatology", "key": "10.1016/j.jdsr.2021.03.001_bib0285", "volume": "212", "year": "2006" }, { "DOI": "10.1007/s40121-018-0200-7", "article-title": "In vitro bactericidal and virucidal efficacy of povidone-iodine gargle/mouthwash against respiratory and oral tract pathogens", "author": "Eggers", "doi-asserted-by": "crossref", "first-page": "249", "journal-title": "Infect Dis Ther", "key": "10.1016/j.jdsr.2021.03.001_bib0290", "volume": "7", "year": "2018" }, { "DOI": "10.1159/000057722", "article-title": "Prevention of respiratory infections by povidone-iodine gargle", "author": "Nagatake", "doi-asserted-by": "crossref", "first-page": "32", "issue": "Suppl", "journal-title": "Dermatology", "key": "10.1016/j.jdsr.2021.03.001_bib0295", "volume": "204", "year": "2002" }, { "article-title": "In-vivo toxicity studies and in-vitro inactivation of SARS-CoV-2 by povidone-iodine in-situ gel forming formulations", "author": "Liang", "journal-title": "bioRxiv Prepr Serv Biol", "key": "10.1016/j.jdsr.2021.03.001_bib0300", "year": "2020" }, { "DOI": "10.1111/odi.13526", "article-title": "Is povidone iodine mouthwash effective against SARS-CoV-2? First in vivo tests", "author": "Martínez Lamas", "doi-asserted-by": "crossref", "journal-title": "Oral Dis", "key": "10.1016/j.jdsr.2021.03.001_bib0305", "year": "2020" }, { "DOI": "10.1016/S2666-5247(20)30003-3", "article-title": "Stability of SARS-CoV-2 in different environmental conditions", "author": "Chin", "doi-asserted-by": "crossref", "first-page": "e10", "journal-title": "Lancet Microbe", "key": "10.1016/j.jdsr.2021.03.001_bib0310", "volume": "1", "year": "2020" }, { "DOI": "10.1038/s41415-020-1589-4", "article-title": "Povidone-iodine", "author": "Challacombe", "doi-asserted-by": "crossref", "first-page": "656", "journal-title": "Br Dent J", "key": "10.1016/j.jdsr.2021.03.001_bib0315", "volume": "228", "year": "2020" }, { "DOI": "10.1016/j.oraloncology.2020.104724", "article-title": "“Personal Protective Equipment” for frontline providers exposed in high-risk head and neck and", "author": "Mady", "doi-asserted-by": "crossref", "first-page": "104724", "journal-title": "Oral Oncol", "key": "10.1016/j.jdsr.2021.03.001_bib0320", "year": "2020" }, { "DOI": "10.5530/ijmedph.2020.4.36", "article-title": "Protection at Portal of Entry (PPE) with povidone iodine for COVID-19", "author": "Shankar", "doi-asserted-by": "crossref", "first-page": "166", "issue": "4", "journal-title": "Int J Med Public Health", "key": "10.1016/j.jdsr.2021.03.001_bib0325", "volume": "10", "year": "2020" }, { "DOI": "10.3109/01480545.2013.846364", "article-title": "Povidone-iodine-induced cell death in cultured human epithelial HeLa cells and rat oral mucosal tissue", "author": "Sato", "doi-asserted-by": "crossref", "first-page": "268", "journal-title": "Drug Chem Toxicol", "key": "10.1016/j.jdsr.2021.03.001_bib0330", "volume": "37", "year": "2014" }, { "article-title": "The use of Betadine antiseptic in the treatment of oral surgical, parodontological and oral mucosal diseases", "author": "Kövesi", "first-page": "243", "journal-title": "Fogorv Sz", "key": "10.1016/j.jdsr.2021.03.001_bib0335", "volume": "92", "year": "1999" }, { "DOI": "10.1007/s10006-019-00800-2", "article-title": "Pneumonia due to aspiration of povidone iodine after preoperative disinfection of the oral cavity", "author": "Hitosugi", "doi-asserted-by": "crossref", "first-page": "507", "journal-title": "Oral Maxillofac Surg", "key": "10.1016/j.jdsr.2021.03.001_bib0340", "volume": "23", "year": "2019" }, { "DOI": "10.4103/jispcd.JISPCD_304_20", "article-title": "A potential antiseptic to minimize the risk of COVID-19? A narrative review", "author": "Castro-Ruiz", "doi-asserted-by": "crossref", "first-page": "681", "issue": "6", "journal-title": "J Int Soc Prev Community Dent", "key": "10.1016/j.jdsr.2021.03.001_bib0345", "volume": "10", "year": "2020" }, { "DOI": "10.6061/clinics/2020/e2328", "article-title": "Potential mouth rinses and nasal sprays that reduce SARS-CoV-2 viral load: what we know so far?", "author": "Gabriel de Toledo", "doi-asserted-by": "crossref", "first-page": "e2328", "journal-title": "Clinics", "key": "10.1016/j.jdsr.2021.03.001_bib0350", "volume": "75", "year": "2020" } ], "reference-count": 70, "references-count": 70, "relation": {}, "resource": { "primary": { "URL": "https://linkinghub.elsevier.com/retrieve/pii/S1882761621000065" } }, "score": 1, "short-title": [], "source": "Crossref", "subject": [], "subtitle": [], "title": "Can povidone iodine gargle/mouthrinse inactivate SARS-CoV-2 and decrease the risk of nosocomial and community transmission during the COVID-19 pandemic? An evidence-based update", "type": "journal-article", "update-policy": "http://dx.doi.org/10.1016/elsevier_cm_policy", "volume": "57" }