Negativización de PCR a SARS-CoV-2 en muestra respiratoria en pacientes con necesidad de asistencia recurrente
et al., Anales de Pediatría, doi:10.1016/j.anpedi.2021.01.006, Apr 2022
HCQ for COVID-19
1st treatment shown to reduce risk in
March 2020, now with p < 0.00000000001 from 424 studies, used in 59 countries.
No treatment is 100% effective. Protocols
combine treatments.
6,200+ studies for
200+ treatments. c19early.org
|
Retrospective 15 pediatric patients in Spain, showing faster viral clearance with HCQ+AZ, without statistical significance. Treatment time and details are not provided.
|
time to viral-, 29.2% lower, relative time 0.71, p = 0.45, treatment median 17.0 IQR 16.0 n=5, control median 24.0 IQR 21.0 n=5, onset to clearance.
|
| Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates |
Bassets-Bosch et al., 30 Apr 2022, retrospective, Spain, peer-reviewed, 5 authors, study period 11 March, 2020 - 30 April, 2020, this trial uses multiple treatments in the treatment arm (combined with AZ) - results of individual treatments may vary.
Contact: cristinalarrosaespinosa@gmail.com, segonzalez@vhebron.net, sgonzalezperis@gmail.com.
Abstract: Anales de Pediatría 96 (2022) 350---371
Figura 1
A) Imagen de dermatoscopia: lesión seudovascular. B) Lesión cupuliforme, irregular, de coloración eritematosa viva.
Bibliografía
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Negativización de PCR a SARS-CoV-2
en muestra respiratoria en pacientes
con necesidad de asistencia
recurrente
SARS-CoV-2 PCR negativization in respiratory
sample in patients with need for recurring
assistance
Sra. Editora:
Además de las consecuencias en términos de morbimortalidad (especialmente en pacientes adultos), la pandemia de
nevi: Comparison with melanomas and common nevi. J Am Acad
Dermatol. 2007;56:815---24.
Cristina Larrosa a,∗ , Antonio Torrelo b , Luis Madero a
y Álvaro Lassaletta a
a
Unidad de Onco-Hematología Pediátrica y Trasplante de
Progenitores Hematopoyéticos, Hospital Universitario Niño
Jesús, Madrid, España
b
Unidad de Dermatología, Hospital Universitario Niño
Jesús, Madrid, España
∗
Autor para correspondencia.
Correo electrónico: cristinalarrosaespinosa@gmail.com
(C. Larrosa).
https://doi.org/10.1016/j.anpedi.2021.01.008
1695-4033/ © 2021 Publicado por Elsevier España, S.L.U. en
nombre de Asociación Española de Pediatrı́a. Este es un artı́culo
Open Access bajo la licencia CC BY-NC-ND (http://
creativecommons.org/licenses/by-nc-nd/4.0/).
SARS-CoV-2/COVID-19 ha amenazado con bloquear los circuitos asistenciales habituales. En este sentido, la detección
de SARS-CoV-2 en pacientes con necesidad de contacto reiterado con el sistema sanitario ha obligado a establecer
estrategias seguras de control clínico y de negativización.
Se analizaron los datos de los pacientes diagnosticados
de infección por SARS-CoV-2 mediante PCR en muestra respiratoria entre el 11 de marzo y el 30 de abril de 2020 en
un hospital terciario pediátrico de referencia de Barcelona
(España), a los que se hubiera practicado posteriormente
un nuevo estudio para comprobar la negativización de la
PCR en aspirado nasofaríngeo. Dicho estudio se realizó a
pacientes con necesidad de asistencia seriada en hospitales de día, procedimientos, hospitalizaciones programadas,
etc. Para estos controles clínicos y de negativización, y pos357
CARTAS CIENTÍFICAS
Tabla 1
Datos de negativización de la PCR a SARS-CoV-2 en función de distintas variables
Total de pacientes
Grupos de
pacientes
Número..
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Late treatment
is less effective
is less effective
