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All Studies   Meta Analysis    Recent:   
0 0.5 1 1.5 2+ Mortality 86% Improvement Relative Risk Vitamin D for COVID-19  Ansari et al.  Sufficiency Are vitamin D levels associated with COVID-19 outcomes? Prospective study of 125 patients in Pakistan (Mar - Aug 2020) Lower mortality with higher vitamin D levels (p=0.02) c19early.org Ansari et al., Pakistan J. Med. Heal. .., Dec 2020 Favors vitamin D Favors control

Frequency of Severe Vitamin D Deficiency and its Association with Mortality in Patients with Corona virus Disease

Ansari et al., Pakistan J. Med. Heal. Sci., 14:4
Dec 2020  
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Vitamin D for COVID-19
8th treatment shown to reduce risk in October 2020
 
*, now known with p < 0.00000000001 from 120 studies, recognized in 8 countries.
No treatment is 100% effective. Protocols combine complementary and synergistic treatments. * >10% efficacy in meta analysis with ≥3 clinical studies.
4,000+ studies for 60+ treatments. c19early.org
Prospective study of 125 severe COVID-19 patients in Pakistan, showing significantly higher mortality with vitamin D deficiency.
This is the 36th of 196 COVID-19 sufficiency studies for vitamin D, which collectively show higher levels reduce risk with p<0.0000000001 (1 in 11,637 vigintillion).
This study is excluded in the after exclusion results of meta analysis: unadjusted results with no group details.
risk of death, 86.0% lower, RR 0.14, p = 0.02, high D levels (≥25nmol/L) 2 of 68 (2.9%), low D levels (<25nmol/L) 12 of 57 (21.1%), NNT 5.5.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Ansari et al., 31 Dec 2020, prospective, Pakistan, peer-reviewed, 6 authors, study period 1 March, 2020 - 31 August, 2020.
This PaperVitamin DAll
Frequency of Severe Vitamin D Deficiency and its Association with Mortality in Patients with Corona virus Disease
Dr Imdad Ali Ansari, Aneel Kumar, Tanveer Ahmed Ansari, Abrar Shaikh, Jawed Akhtar Samo
Aim: To determine the frequency of severe vitamin D deficiency and its association with mortality in patients presented with Covid-19.
References
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Biesalski, Vitamin D deficiency and co-morbidities in COVID-19 patients -a fatal relationship?, NFS J
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Cucinotta, Vanelli, WHO Declares COVID-19 a Pandemic, Acta Biomedica: Atenei Parmensis
D'avolio, Avataneo, Manca, Cusato, Nicolo et al., 25-hydroxyvitamin D concentrations are lower in patients with positive PCR for SARS-CoV-2, Nutrients
Forrest, Stuhldreher, Prevalence and correlates of vitamin D deficiency in US adults, Nutr Res
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Grant, Lahore, Mcdonnell, Baggerly, French et al., Evidence that vitamin D supplementation could reduce risk of influenza and COVID-19 infections and deaths, Nutrients
Gruber-Bzura, Vitamin D and Influenza-Prevention or Therapy?, Int J Molecular Sci
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Ilie, Stefanescu, Smith, The role of vitamin D in the prevention of coronavirus disease 2019 infection and mortality, Aging Clin Exp Res
Lamers, Beumer, Van Der Vaart, Knoops, Puschhof et al., SARS-CoV-2 productively infects human gut enterocytes, Science
Maghbooli, Sahraian, Ebrahimi, Pazoki, Kafan et al., Vitamin D sufficiency, a serum 25-hydroxyvitamin D at least 30 ng/mL reduced risk for adverse clinical outcomes in patients with COVID-19 infection, PLoS ONE
Martineau, Jolliffe, Hooper, Greenberg, Aloia et al., Vitamin D supplementation to prevent acute respiratory tract infections: systematic review and meta-analysis of individual participant data, BMJ
Ortega, Serrano, Pujol, Rangel, Role of changes in SARS-CoV-2 spike protein in the interaction with the human ACE2 receptor: An in silico analysis, EXCLI journal
Owah, Fan, Dennett, Hagtvedt, Straube, Vitamin D levels and deficiency with different occupations: a systematic review, BMC Public Health
Panarese, Shahini, COVID-19, and vitamin D, Aliment Pharm Ther
Umhau, Casting sunlight on an epidemic: is vitamin D a critical host factor to prevent COVID-19?, Med Page Today
Xu, Shi, Wang, Zhang, Huang et al., Pathological findings of COVID-19 associated with acute respiratory distress syndrome, Lancet Respiratory Med
Xu, Yang, Chen, Luo, Zhang et al., Vitamin D alleviates lipopolysaccharide induced acute lung injury via regulation of the reninangiotensin system, Molecular Med Reports
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