Immune stimulatory effect of Nigella sativa in healthy animal models: A systematic review and meta-analysis

{ 'indexed': {'date-parts': [[2024, 7, 13]], 'date-time': '2024-07-13T00:19:32Z', 'timestamp': 1720829972342}, 'reference-count': 45, 'publisher': 'Elsevier BV', 'issue': '6', 'license': [ { 'start': { 'date-parts': [[2024, 3, 1]], 'date-time': '2024-03-01T00:00:00Z', 'timestamp': 1709251200000}, 'content-version': 'tdm', 'delay-in-days': 0, 'URL': 'https://www.elsevier.com/tdm/userlicense/1.0/'}, { 'start': { 'date-parts': [[2024, 3, 1]], 'date-time': '2024-03-01T00:00:00Z', 'timestamp': 1709251200000}, 'content-version': 'tdm', 'delay-in-days': 0, 'URL': 'https://www.elsevier.com/legal/tdmrep-license'}, { 'start': { 'date-parts': [[2024, 2, 28]], 'date-time': '2024-02-28T00:00:00Z', 'timestamp': 1709078400000}, 'content-version': 'vor', 'delay-in-days': 0, 'URL': 'http://creativecommons.org/licenses/by-nc-nd/4.0/'}], 'content-domain': { 'domain': ['cell.com', 'elsevier.com', 'sciencedirect.com'], 'crossmark-restriction': True}, 'published-print': {'date-parts': [[2024, 3]]}, 'DOI': '10.1016/j.heliyon.2024.e27390', 'type': 'journal-article', 'created': {'date-parts': [[2024, 3, 9]], 'date-time': '2024-03-09T03:54:47Z', 'timestamp': 1709956487000}, 'page': 'e27390', 'update-policy': 'http://dx.doi.org/10.1016/elsevier_cm_policy', 'source': 'Crossref', 'is-referenced-by-count': 0, 'title': 'Immune stimulatory effect of Nigella sativa in healthy animal models: A systematic review and ' 'meta-analysis', 'prefix': '10.1016', 'volume': '10', 'author': [ {'given': 'Abdulsamad', 'family': 'Alsalahi', 'sequence': 'first', 'affiliation': []}, { 'ORCID': 'http://orcid.org/0000-0002-2908-8566', 'authenticated-orcid': False, 'given': 'Nian N.N.', 'family': 'Maarof', 'sequence': 'additional', 'affiliation': []}, { 'ORCID': 'http://orcid.org/0000-0001-8342-5183', 'authenticated-orcid': False, 'given': 'Mohammed A.', 'family': 'Alshawsh', 'sequence': 'additional', 'affiliation': []}, { 'ORCID': 'http://orcid.org/0000-0001-6533-7868', 'authenticated-orcid': False, 'given': 'Musheer A.', 'family': 'Aljaberi', 'sequence': 'additional', 'affiliation': []}, {'given': 'Mousa A.', 'family': 'Qasem', 'sequence': 'additional', 'affiliation': []}, {'given': 'Abdulaleem', 'family': 'Mahuob', 'sequence': 'additional', 'affiliation': []}, {'given': 'Nassrin A.', 'family': 'Badroon', 'sequence': 'additional', 'affiliation': []}, {'given': 'Ebthag A.M.', 'family': 'Mussa', 'sequence': 'additional', 'affiliation': []}, { 'ORCID': 'http://orcid.org/0000-0001-6288-3791', 'authenticated-orcid': False, 'given': 'Rukman A.', 'family': 'Hamat', 'sequence': 'additional', 'affiliation': []}, { 'ORCID': 'http://orcid.org/0000-0003-4812-956X', 'authenticated-orcid': False, 'given': 'Atiyah M.', 'family': 'Abdallah', 'sequence': 'additional', 'affiliation': []}], 'member': '78', 'reference': [ { 'key': '10.1016/j.heliyon.2024.e27390_bib1', 'doi-asserted-by': 'crossref', 'DOI': '10.1016/j.hermed.2020.100404', 'article-title': 'An updated knowledge of Black seed (Nigella sativa Linn.): review of ' 'phytochemical constituents and pharmacological properties', 'volume': '25', 'author': 'Ahmad', 'year': '2021', 'journal-title': 'J. Herb. Med.'}, { 'key': '10.1016/j.heliyon.2024.e27390_bib2', 'doi-asserted-by': 'crossref', 'first-page': '304', 'DOI': '10.1016/j.sbspro.2014.01.1131', 'article-title': 'The new miracle of habbatus sauda: its major component thymoquinone can ' 'be used in the management of autoimmune diseases', 'volume': '121', 'author': 'Osman', 'year': '2014', 'journal-title': 'Procedia Soc. Behav. Sci.'}, { 'issue': '2', 'key': '10.1016/j.heliyon.2024.e27390_bib3', 'first-page': '115', 'article-title': 'An updated literature-based review: phytochemistry, pharmacology and ' 'therapeutic promises of Nigella sativa L. Orient', 'volume': '19', 'author': 'Islam', 'year': '2019', 'journal-title': 'Pharm. Exp. Med.'}, { 'issue': '10', 'key': '10.1016/j.heliyon.2024.e27390_bib4', 'first-page': '732', 'article-title': 'Phytochemistry, pharmacology, and therapeutic uses of black seed ' '(Nigella sativa)', 'volume': '14', 'author': 'Kooti', 'year': '2016', 'journal-title': 'Chin. J. Nat. Med.'}, { 'issue': '16', 'key': '10.1016/j.heliyon.2024.e27390_bib5', 'doi-asserted-by': 'crossref', 'first-page': '9078', 'DOI': '10.3390/ijms22169078', 'article-title': 'Protective effects of black cumin (nigella sativa) and its bioactive ' 'constituent, thymoquinone against kidney injury: an aspect on ' 'pharmacological insights', 'volume': '22', 'author': 'Hannan', 'year': '2021', 'journal-title': 'Int. J. Mol. Sci.'}, { 'issue': '6', 'key': '10.1016/j.heliyon.2024.e27390_bib6', 'doi-asserted-by': 'crossref', 'first-page': '1784', 'DOI': '10.3390/nu13061784', 'article-title': 'Black cumin (nigella sativa L.): a comprehensive review on ' 'phytochemistry, health benefits, molecular pharmacology, and safety', 'volume': '13', 'author': 'Hannan', 'year': '2021', 'journal-title': 'Nutrients'}, { 'key': '10.1016/j.heliyon.2024.e27390_bib7', 'doi-asserted-by': 'crossref', 'DOI': '10.1016/j.foodchem.2019.125740', 'article-title': 'Solvent and temperature effects of accelerated solvent extraction (ASE) ' 'coupled with ultra-high pressure liquid chromatography (UHPLC-DAD) ' 'technique for determination of thymoquinone in commercial food samples ' 'of black seeds (Nigella sativa)', 'volume': '309', 'author': 'Ahmad', 'year': '2020', 'journal-title': 'Food Chem.'}, { 'issue': '1', 'key': '10.1016/j.heliyon.2024.e27390_bib8', 'doi-asserted-by': 'crossref', 'first-page': '1', 'DOI': '10.1186/1479-5876-12-82', 'article-title': 'A randomised controlled trial on hypolipidemic effects of Nigella ' 'Sativa seeds powder in menopausal women', 'volume': '12', 'author': 'Ibrahim', 'year': '2014', 'journal-title': 'J. Transl. Med.'}, { 'issue': '5', 'key': '10.1016/j.heliyon.2024.e27390_bib9', 'doi-asserted-by': 'crossref', 'first-page': '487', 'DOI': '10.1080/01480545.2019.1617301', 'article-title': 'The effect of chronic supplementation of Nigella sativa on splenocytes ' 'response in rats following treadmill exercise', 'volume': '44', 'author': 'Gholamnezhad', 'year': '2021', 'journal-title': 'Drug Chem. Toxicol.'}, { 'key': '10.1016/j.heliyon.2024.e27390_bib10', 'doi-asserted-by': 'crossref', 'DOI': '10.1016/j.jep.2020.112585', 'article-title': 'Effects of Nigella sativa on endothelial dysfunction in diabetes ' 'mellitus: a review', 'volume': '252', 'author': 'Mohebbati', 'year': '2020', 'journal-title': 'J. Ethnopharmacol.'}, { 'issue': '1', 'key': '10.1016/j.heliyon.2024.e27390_bib11', 'doi-asserted-by': 'crossref', 'first-page': '295', 'DOI': '10.1016/j.intimp.2015.06.023', 'article-title': 'Immunomodulatory and anti-inflammatory action of Nigella sativa and ' 'thymoquinone: a comprehensive review', 'volume': '28', 'author': 'Majdalawieh', 'year': '2015', 'journal-title': 'Int. Immunopharm.'}, { 'issue': '6', 'key': '10.1016/j.heliyon.2024.e27390_bib12', 'doi-asserted-by': 'crossref', 'first-page': '2968', 'DOI': '10.1002/ptr.7003', 'article-title': 'The effects of Nigella sativa on respiratory, allergic and immunologic ' 'disorders, evidence from experimental and clinical studies, a ' 'comprehensive and updated review', 'volume': '35', 'author': 'Saadat', 'year': '2021', 'journal-title': 'Phytother Res.'}, { 'issue': '3', 'key': '10.1016/j.heliyon.2024.e27390_bib13', 'doi-asserted-by': 'crossref', 'first-page': '1329', 'DOI': '10.1002/ptr.6895', 'article-title': 'Revisiting pharmacological potentials of Nigella sativa seed: a ' 'promising option for COVID-19 prevention and cure', 'volume': '35', 'author': 'Islam', 'year': '2021', 'journal-title': 'Phytother Res.'}, { 'issue': '5494', 'key': '10.1016/j.heliyon.2024.e27390_bib14', 'doi-asserted-by': 'crossref', 'first-page': '1168', 'DOI': '10.1126/science.290.5494.1168', 'article-title': 'Promiscuity and the primate immune system', 'volume': '290', 'author': 'Nunn', 'year': '2000', 'journal-title': 'Science'}, { 'issue': '6', 'key': '10.1016/j.heliyon.2024.e27390_bib15', 'doi-asserted-by': 'crossref', 'first-page': '492', 'DOI': '10.1038/s41422-020-0332-7', 'article-title': 'Interaction between microbiota and immunity in health and disease', 'volume': '30', 'author': 'Zheng', 'year': '2020', 'journal-title': 'Cell Res.'}, { 'issue': '6', 'key': '10.1016/j.heliyon.2024.e27390_bib16', 'doi-asserted-by': 'crossref', 'first-page': '375', 'DOI': '10.1038/s41577-020-0285-6', 'article-title': 'Defining trained immunity and its role in health and disease', 'volume': '20', 'author': 'Netea', 'year': '2020', 'journal-title': 'Nat. Rev. Immunol.'}, { 'key': '10.1016/j.heliyon.2024.e27390_bib17', 'doi-asserted-by': 'crossref', 'first-page': '677', 'DOI': '10.1146/annurev.cellbio.22.010605.093317', 'article-title': 'Blood cells and blood cell development in the animal kingdom', 'volume': '22', 'author': 'Hartenstein', 'year': '2006', 'journal-title': 'Annu. Rev. Cell Dev. Biol.'}, { 'issue': '9', 'key': '10.1016/j.heliyon.2024.e27390_bib18', 'doi-asserted-by': 'crossref', 'first-page': '1564', 'DOI': '10.1177/0748233714566294', 'article-title': 'Effects of formaldehyde inhalation on humoral immunity and protective ' 'effect of Nigella sativa oil: an experimental study', 'volume': '32', 'author': 'Sapmaz', 'year': '2016', 'journal-title': 'Toxicol. Ind. Health'}, { 'issue': '1', 'key': '10.1016/j.heliyon.2024.e27390_bib19', 'doi-asserted-by': 'crossref', 'first-page': '72', 'DOI': '10.7762/cnr.2021.10.1.72', 'article-title': 'The effects of nigella sativa supplementation on liver enzymes levels: ' 'a systematic review and meta-analysis of randomized controlled trials', 'volume': '10', 'author': 'Azizi', 'year': '2021', 'journal-title': 'Clin. Nutr. Res.'}, { 'issue': '10', 'key': '10.1016/j.heliyon.2024.e27390_bib20', 'doi-asserted-by': 'crossref', 'first-page': '2586', 'DOI': '10.1002/ptr.6708', 'article-title': 'Effects of Nigella sativa on glycemic control, lipid profiles, and ' 'biomarkers of inflammatory and oxidative stress: a systematic review ' 'and meta‐analysis of randomized controlled clinical trials', 'volume': '34', 'author': 'Hallajzadeh', 'year': '2020', 'journal-title': 'Phytother Res.'}, { 'issue': '5', 'key': '10.1016/j.heliyon.2024.e27390_bib21', 'doi-asserted-by': 'crossref', 'first-page': '1630', 'DOI': '10.3390/ijerph17051630', 'article-title': 'Comment on: effects of nigella sativa on type-2 diabetes mellitus: a ' 'systematic review', 'volume': '17', 'author': 'Hassan', 'year': '2020', 'journal-title': 'Int. J. Environ. Res. Publ. Health'}, { 'key': '10.1016/j.heliyon.2024.e27390_bib22', 'doi-asserted-by': 'crossref', 'DOI': '10.1016/j.ctim.2020.102535', 'article-title': 'Effect of Nigella sativa L. supplementation on inflammatory and ' 'oxidative stress indicators: a systematic review and meta-analysis of ' 'controlled clinical trials', 'volume': '54', 'author': 'Mohit', 'year': '2020', 'journal-title': 'Compl. Ther. Med.'}, { 'key': '10.1016/j.heliyon.2024.e27390_bib23', 'doi-asserted-by': 'crossref', 'DOI': '10.1016/j.phrs.2020.104767', 'article-title': 'The effect of Nigella sativa on the measures of liver and kidney ' 'parameters: a systematic review and meta-analysis of ' 'randomized-controlled trials', 'volume': '156', 'author': 'Razmpoosh', 'year': '2020', 'journal-title': 'Pharmacol. Res.'}, { 'issue': '1', 'key': '10.1016/j.heliyon.2024.e27390_bib24', 'first-page': '75', 'article-title': 'Immune-responsiveness and performance of broiler chickens fed black ' 'cumin (Nigella Sativa L.) powder', 'volume': '13', 'author': 'Al-Mufarrej', 'year': '2014', 'journal-title': 'J. Saudi Soc. Agric. Sci.'}, { 'key': '10.1016/j.heliyon.2024.e27390_bib25', 'first-page': '788', 'article-title': 'Effect of dietary supplementation of different levels of black seed ' '(Nigella Sativa L.) on growth performance, immunological, hematological ' 'and carcass parameters of broiler chicks', 'volume': '77', 'author': 'Shewita', 'year': '2011', 'journal-title': 'World acad. eng. technol.'}, { 'issue': '8', 'key': '10.1016/j.heliyon.2024.e27390_bib26', 'doi-asserted-by': 'crossref', 'first-page': '451', 'DOI': '10.3923/ijps.2013.451.455', 'article-title': 'Immunomodulation of black seed in two strains of laying hens', 'volume': '12', 'author': 'Al-Khalifa', 'year': '2013', 'journal-title': 'Int. J. Poultry Sci.'}, { 'issue': '3', 'key': '10.1016/j.heliyon.2024.e27390_bib27', 'doi-asserted-by': 'crossref', 'first-page': '515', 'DOI': '10.1080/08923970500242327', 'article-title': 'Immunomodulating effects of black seed and oxytetracycline in pigeons', 'volume': '27', 'author': 'Al-Ankari', 'year': '2005', 'journal-title': 'Immunopharmacol. Immunotoxicol.'}, { 'issue': '5', 'key': '10.1016/j.heliyon.2024.e27390_bib28', 'doi-asserted-by': 'crossref', 'first-page': '1011', 'DOI': '10.1007/s11250-018-1525-7', 'article-title': 'Influence of Nigella sativa seeds, Rosmarinus officinalis leaves and ' 'their combination on growth performance, immune response and rumen ' 'metabolism in Dorper lambs', 'volume': '50', 'author': 'Odhaib', 'year': '2018', 'journal-title': 'Trop. Anim. Health Prod.'}, { 'issue': '1–3', 'key': '10.1016/j.heliyon.2024.e27390_bib29', 'doi-asserted-by': 'crossref', 'first-page': '173', 'DOI': '10.1016/j.livsci.2010.01.021', 'article-title': 'Growth performance, serum biochemistry and blood hematology of broiler ' 'chicks fed different levels of black seed (Nigella sativa) and ' 'peppermint (Mentha piperita)', 'volume': '129', 'author': 'Toghyani', 'year': '2010', 'journal-title': 'Livest. Sci.'}, { 'issue': '6', 'key': '10.1016/j.heliyon.2024.e27390_bib30', 'first-page': '699', 'article-title': 'Efficacy of Nigella sativa in alleviating benzo[a]pyrene-induced ' 'immunotoxicity in broilers', 'volume': '26', 'author': 'Latif', 'year': '2011', 'journal-title': 'Histol. Histopathol.'}, { 'issue': '5', 'key': '10.1016/j.heliyon.2024.e27390_bib31', 'doi-asserted-by': 'crossref', 'DOI': '10.1016/j.psj.2021.01.028', 'article-title': 'Response of lymphatic tissues to natural feed additives, curcumin ' '(Curcuma longa) and black cumin seeds (Nigella sativa), in broilers ' 'against Pasteurella multocida', 'volume': '100', 'author': 'Raheem', 'year': '2021', 'journal-title': 'Poultry Sci.'}, { 'issue': '3', 'key': '10.1016/j.heliyon.2024.e27390_bib32', 'doi-asserted-by': 'crossref', 'first-page': '999', 'DOI': '10.1007/s11250-019-02091-x', 'article-title': 'Hematologic, lipid profile, immunity, and antioxidant status of growing ' 'rabbits fed black seed as natural antioxidants', 'volume': '52', 'author': 'El-Gindy', 'year': '2020', 'journal-title': 'Trop. Anim. Health Prod.'}, { 'issue': '1', 'key': '10.1016/j.heliyon.2024.e27390_bib33', 'doi-asserted-by': 'crossref', 'first-page': '13', 'DOI': '10.1080/01652176.2013.782119', 'article-title': 'Effects of black cumin seed (Nigella sativa L.) on performance and ' 'immune system in newly evolved crossbred laying hens', 'volume': '33', 'author': 'Khan', 'year': '2013', 'journal-title': 'Vet. Q.'}, { 'issue': '1', 'key': '10.1016/j.heliyon.2024.e27390_bib34', 'first-page': '183', 'article-title': 'Duration of feeding black seed (Nigella sativa) to broiler chicks and ' 'its effect on immune response, cholesterol and gut microflora', 'volume': '7', 'author': 'Karmous', 'year': '2016', 'journal-title': 'Res. J. Pharmaceut. Biol. Chem. Sci.'}, { 'issue': '3', 'key': '10.1016/j.heliyon.2024.e27390_bib35', 'doi-asserted-by': 'crossref', 'first-page': '185', 'DOI': '10.14710/jitaa.38.3.185-191', 'article-title': 'Physiological responses of blood and immune organs of broiler chicken ' 'fed dietary black cumin powder (nigella sativa) during dry seasons', 'volume': '38', 'author': 'Salam', 'year': '2013', 'journal-title': 'J. Indones. Trop. Anim. Agric.'}, { 'issue': '6', 'key': '10.1016/j.heliyon.2024.e27390_bib36', 'article-title': 'Immunomodulation of Nile tilapia, Oreochromis niloticus, by nigella ' 'sativa and bacillus subtilis', 'volume': '3', 'author': 'Elkamel', 'year': '2012', 'journal-title': 'J. Aquacult. Res. Dev.'}, { 'issue': '1', 'key': '10.1016/j.heliyon.2024.e27390_bib37', 'doi-asserted-by': 'crossref', 'first-page': '128', 'DOI': '10.1016/j.livsci.2014.03.014', 'article-title': 'Effects of black cumin seed (Nigella sativa L.), a probiotic, a ' 'prebiotic and a synbiotic on growth performance, immune response and ' 'blood characteristics of male broilers', 'volume': '164', 'author': 'Ghasemi', 'year': '2014', 'journal-title': 'Livest. Sci.'}, { 'key': '10.1016/j.heliyon.2024.e27390_bib38', 'first-page': '2021', 'article-title': 'Effects of nigella sativa on performance, blood profiles, and antibody ' 'titer against newcastle disease in broilers', 'author': 'Talebi', 'year': '2021', 'journal-title': 'Evid.-based Complement. Altern. Med.'}, { 'issue': '4', 'key': '10.1016/j.heliyon.2024.e27390_bib39', 'doi-asserted-by': 'crossref', 'first-page': '204', 'DOI': '10.3923/pjn.2014.204.210', 'article-title': 'Effect of garlic, black seed and turmeric on the growth of broiler ' 'chicken', 'volume': '13', 'author': 'Ali', 'year': '2014', 'journal-title': 'Pakistan J. Nutr.'}, { 'issue': '5', 'key': '10.1016/j.heliyon.2024.e27390_bib40', 'doi-asserted-by': 'crossref', 'first-page': '337', 'DOI': '10.1016/S2221-1691(13)60075-1', 'article-title': 'A review on therapeutic potential of Nigella sativa: a miracle herb', 'volume': '3', 'author': 'Ahmad', 'year': '2013', 'journal-title': 'Asian Pac. J. Trop. Biomed.'}, { 'issue': '3', 'key': '10.1016/j.heliyon.2024.e27390_bib41', 'doi-asserted-by': 'crossref', 'first-page': '1028', 'DOI': '10.3390/nu13031028', 'article-title': "Efficacy of Edible bird's nest on cognitive functions in experimental " 'animal models: a systematic review', 'volume': '13', 'author': 'Ismail', 'year': '2021', 'journal-title': 'Nutrients'}, { 'issue': 'Suppl 1', 'key': '10.1016/j.heliyon.2024.e27390_bib42', 'first-page': '29', 'article-title': 'Meta-analysis in medical research', 'volume': '14', 'author': 'Haidich', 'year': '2010', 'journal-title': 'Hippokratia'}, { 'issue': '4', 'key': '10.1016/j.heliyon.2024.e27390_bib43', 'doi-asserted-by': 'crossref', 'first-page': '2', 'DOI': '10.1128/microbiolspec.AID-0019-2014', 'article-title': 'Functions of antibodies', 'volume': '2', 'author': 'Forthal', 'year': '2014', 'journal-title': 'Microbiol. Spectr.'}, { 'issue': '1', 'key': '10.1016/j.heliyon.2024.e27390_bib44', 'doi-asserted-by': 'crossref', 'first-page': '1', 'DOI': '10.1186/1471-2288-14-43', 'article-title': "SYRCLE's risk of bias tool for animal studies", 'volume': '14', 'author': 'Hooijmans', 'year': '2014', 'journal-title': 'BMC Med. Res. Methodol.'}, { 'issue': '2', 'key': '10.1016/j.heliyon.2024.e27390_bib45', 'doi-asserted-by': 'crossref', 'first-page': '521', 'DOI': '10.3390/nu12020521', 'article-title': 'Safety and neuroprotective efficacy of palm oil and tocotrienol-rich ' 'fraction from palm oil: a systematic review', 'volume': '12', 'author': 'Ismail', 'year': '2020', 'journal-title': 'Nutrients'}], 'container-title': 'Heliyon', 'original-title': [], 'language': 'en', 'link': [ { 'URL': 'https://api.elsevier.com/content/article/PII:S2405844024034212?httpAccept=text/xml', 'content-type': 'text/xml', 'content-version': 'vor', 'intended-application': 'text-mining'}, { 'URL': 'https://api.elsevier.com/content/article/PII:S2405844024034212?httpAccept=text/plain', 'content-type': 'text/plain', 'content-version': 'vor', 'intended-application': 'text-mining'}], 'deposited': { 'date-parts': [[2024, 7, 12]], 'date-time': '2024-07-12T05:59:03Z', 'timestamp': 1720763943000}, 'score': 1, 'resource': {'primary': {'URL': 'https://linkinghub.elsevier.com/retrieve/pii/S2405844024034212'}}, 'subtitle': [], 'short-title': [], 'issued': {'date-parts': [[2024, 3]]}, 'references-count': 45, 'journal-issue': {'issue': '6', 'published-print': {'date-parts': [[2024, 3]]}}, 'alternative-id': ['S2405844024034212'], 'URL': 'http://dx.doi.org/10.1016/j.heliyon.2024.e27390', 'relation': {}, 'ISSN': ['2405-8440'], 'subject': [], 'container-title-short': 'Heliyon', 'published': {'date-parts': [[2024, 3]]}, 'assertion': [ {'value': 'Elsevier', 'name': 'publisher', 'label': 'This article is maintained by'}, { 'value': 'Immune stimulatory effect of Nigella sativa in healthy animal models: A ' 'systematic review and meta-analysis', 'name': 'articletitle', 'label': 'Article Title'}, {'value': 'Heliyon', 'name': 'journaltitle', 'label': 'Journal Title'}, { 'value': 'https://doi.org/10.1016/j.heliyon.2024.e27390', 'name': 'articlelink', 'label': 'CrossRef DOI link to publisher maintained version'}, {'value': 'article', 'name': 'content_type', 'label': 'Content Type'}, { 'value': '© 2024 The Authors. Published by Elsevier Ltd.', 'name': 'copyright', 'label': 'Copyright'}], 'article-number': 'e27390'}