Association of Vitamin D Levels, Race/Ethnicity, and Clinical Characteristics With COVID-19 Test Results

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'3693', 'DOI': '10.1111/febs.v287.17', 'article-title': 'Low plasma 25(OH) vitamin D level is associated with increased risk of ' 'COVID-19 infection: an Israeli population-based study.', 'volume': '287', 'author': 'Merzon', 'year': '2020', 'journal-title': 'FEBS J'}, { 'issue': '9', 'key': 'zoi210150r13', 'doi-asserted-by': 'crossref', 'DOI': '10.1371/journal.pone.0239252', 'article-title': 'SARS-CoV-2 positivity rates associated with circulating ' '25-hydroxyvitamin D levels.', 'volume': '15', 'author': 'Kaufman', 'year': '2020', 'journal-title': 'PLoS One'}, { 'issue': '4', 'key': 'zoi210150r15', 'doi-asserted-by': 'publisher', 'first-page': '988', 'DOI': '10.3390/nu12040988', 'article-title': 'Evidence that vitamin D supplementation could reduce risk of influenza ' 'and COVID-19 infections and deaths.', 'volume': '12', 'author': 'Grant', 'year': '2020', 'journal-title': 'Nutrients'}, { 'issue': '8', 'key': 'zoi210150r16', 'doi-asserted-by': 'crossref', 'DOI': '10.1002/dmrr.3375', 'article-title': 'Vitamin D status as a predictor of COVID-19 risk in Black, Asian and ' 'other ethnic minority groups in the UK.', 'volume': '36', 'author': 'Boucher', 'year': '2020', 'journal-title': 'Diabetes Metab Res Rev'}, { 'issue': '11', 'key': 'zoi210150r21', 'doi-asserted-by': 'publisher', 'first-page': '1128', 'DOI': '10.1097/00005650-199911000-00005', 'article-title': 'The performance of different lookback periods and sources of ' 'information for Charlson comorbidity adjustment in Medicare claims.', 'volume': '37', 'author': 'Zhang', 'year': '1999', 'journal-title': 'Med Care'}, { 'issue': '10', 'key': 'zoi210150r23', 'doi-asserted-by': 'publisher', 'first-page': '940', 'DOI': '10.1093/aje/kwg074', 'article-title': 'Estimating the relative risk in cohort studies and clinical trials of ' 'common outcomes.', 'volume': '157', 'author': 'McNutt', 'year': '2003', 'journal-title': 'Am J Epidemiol'}, { 'issue': '1', 'key': 'zoi210150r25', 'doi-asserted-by': 'publisher', 'first-page': '5', 'DOI': '10.1002/(ISSN)1521-4036', 'article-title': 'Parameter estimation and goodness-of-fit in log binomial regression.', 'volume': '48', 'author': 'Blizzard', 'year': '2006', 'journal-title': 'Biom J'}, { 'key': 'zoi210150r26', 'doi-asserted-by': 'publisher', 'first-page': 'l4673', 'DOI': '10.1136/bmj.l4673', 'article-title': 'Association between vitamin D supplementation and mortality: systematic ' 'review and meta-analysis.', 'volume': '366', 'author': 'Zhang', 'year': '2019', 'journal-title': 'BMJ'}, { 'issue': '8', 'key': 'zoi210150r27', 'doi-asserted-by': 'publisher', 'first-page': '459', 'DOI': '10.1038/nrneph.2012.112', 'article-title': 'Effect of race and genetics on vitamin D metabolism, bone and vascular ' 'health.', 'volume': '8', 'author': 'Freedman', 'year': '2012', 'journal-title': 'Nat Rev Nephrol'}, { 'issue': '4', 'key': 'zoi210150r28', 'doi-asserted-by': 'publisher', 'first-page': '561', 'DOI': '10.1016/j.dsx.2020.04.050', 'article-title': 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'zoi210150r32', 'doi-asserted-by': 'publisher', 'first-page': '111', 'DOI': '10.1530/EC-16-0078', 'article-title': 'The variation in free 25-hydroxy vitamin D and vitamin D-binding ' 'protein with season and vitamin D status.', 'volume': '6', 'author': 'Oleröd', 'year': '2017', 'journal-title': 'Endocr Connect'}, { 'key': 'zoi210150r33', 'first-page': '317', 'article-title': 'Binding protein, total and free vitamin D levels in different ' 'physiological and pathophysiological conditions front.', 'volume': '10', 'author': 'Bikle', 'year': '2019', 'journal-title': 'Endocrinol'}, { 'issue': '6', 'key': 'zoi210150r34', 'doi-asserted-by': 'crossref', 'DOI': '10.1371/journal.pone.0065835', 'article-title': 'Vitamin D and respiratory tract infections: a systematic review and ' 'meta-analysis of randomized controlled trials.', 'volume': '8', 'author': 'Bergman', 'year': '2013', 'journal-title': 'PLoS One'}, { 'key': 'zoi210150r36', 'doi-asserted-by': 'publisher', 'first-page': '228', 'DOI': '10.1016/j.jsbmb.2018.12.010', 'article-title': 'Daily oral dosing of vitamin D3 using 5000 to 50,000 international ' 'units a day in long-term hospitalized patients: insights from a seven ' 'year experience.', 'volume': '189', 'author': 'McCullough', 'year': '2019', 'journal-title': 'J Steroid Biochem Mol Biol'}, { 'issue': '12', 'key': 'zoi210150r37', 'doi-asserted-by': 'publisher', 'first-page': '1258', 'DOI': '10.4158/EP13518.OR', 'article-title': 'The vitamin d dose response in obesity.', 'volume': '20', 'author': 'Dhaliwal', 'year': '2014', 'journal-title': 'Endocr Pract'}, { 'issue': '4', 'key': 'zoi210150r38', 'doi-asserted-by': 'crossref', 'DOI': '10.1210/clinem/dgz212', 'article-title': 'Safety of high-dose vitamin D supplementation: secondary analysis of a ' 'randomized controlled trial.', 'volume': '105', 'author': 'Billington', 'year': '2020', 'journal-title': 'J Clin Endocrinol Metab'}, { 'issue': '15', 'key': 'zoi210150r39', 'doi-asserted-by': 'publisher', 'first-page': '458', 'DOI': '10.15585/mmwr.mm6915e3', 'article-title': 'Hospitalization rates and characteristics of patients hospitalized with ' 'laboratory-confirmed coronavirus disease 2019—COVID-NET, 14 states, ' 'March 1-30, 2020.', 'volume': '69', 'author': 'Garg', 'year': '2020', 'journal-title': 'MMWR Morb Mortal Wkly Rep'}, { 'issue': '9', 'key': 'zoi210150r40', 'doi-asserted-by': 'publisher', 'first-page': '781', 'DOI': '10.1016/j.tim.2018.02.007', 'article-title': 'Within-host evolution of human influenza virus.', 'volume': '26', 'author': 'Xue', 'year': '2018', 'journal-title': 'Trends Microbiol'}, { 'issue': '7', 'key': 'zoi210150r41', 'doi-asserted-by': 'publisher', 'first-page': '2502', 'DOI': '10.3390/nu5072502', 'article-title': 'Vitamin D and immune function.', 'volume': '5', 'author': 'Prietl', 'year': '2013', 'journal-title': 'Nutrients'}, { 'issue': '11', 'key': 'zoi210150r42', 'doi-asserted-by': 'publisher', 'first-page': '649', 'DOI': '10.3390/biom9110649', 'article-title': 'Emerging role of vitamin D and its associated molecules in pathways ' 'related to pathogenesis of thrombosis.', 'volume': '9', 'author': 'Mohammad', 'year': '2019', 'journal-title': 'Biomolecules'}, { 'issue': '15', 'key': 'zoi210150r44', 'doi-asserted-by': 'publisher', 'first-page': '477', 'DOI': '10.15585/mmwr.mm6915e6', 'article-title': 'Characteristics of Health Care Personnel with COVID-19—United States, ' 'February 12-April 9, 2020.', 'volume': '69', 'author': 'CDC COVID-19 Response Team', 'year': '2020', 'journal-title': 'MMWR Morb Mortal Wkly Rep'}, { 'issue': '2-3', 'key': 'zoi210150r45', 'doi-asserted-by': 'publisher', 'first-page': '164', 'DOI': '10.3402/ijch.v67i2-3.18258', 'article-title': 'Vitamin D and living in northern latitudes—an endemic risk area for ' 'vitamin D deficiency.', 'volume': '67', 'author': 'Huotari', 'year': '2008', 'journal-title': 'Int J Circumpolar Health'}, { 'issue': '6', 'key': 'zoi210150r46', 'doi-asserted-by': 'publisher', 'first-page': '702', 'DOI': '10.1592/phco.23.6.702.32182', 'article-title': 'Fracture risks for women in long-term care: high prevalence of ' 'calcaneal osteoporosis and hypovitaminosis D.', 'volume': '23', 'author': 'Elliott', 'year': '2003', 'journal-title': 'Pharmacotherapy'}, { 'issue': '1', 'key': 'zoi210150r47', 'doi-asserted-by': 'publisher', 'first-page': '519', 'DOI': '10.1186/s12889-017-4436-z', 'article-title': 'Vitamin D levels and deficiency with different occupations: a ' 'systematic review.', 'volume': '17', 'author': 'Sowah', 'year': '2017', 'journal-title': 'BMC Public Health'}, { 'key': 'zoi210150r4', 'volume-title': 'Dietary Reference Intakes for Calcium and Vitamin D.', 'author': 'Del Valle', 'year': '2011'}, { 'key': 'zoi210150r22', 'doi-asserted-by': 'crossref', 'DOI': '10.1007/978-1-4899-3242-6', 'volume-title': 'Generalized Linear Models', 'author': 'McCullagh', 'year': '1989', 'edition': '2nd ed'}, { 'key': 'zoi210150r35', 'volume-title': 'Vitamin D Status: United States 2001–2006. NCHS Data Brief, No 59', 'author': 'Looker', 'year': '2011'}, { 'key': 'zoi210150r14', 'doi-asserted-by': 'crossref', 'unstructured': 'Israel? A, Assi Cicurel? AA, Feldhamer? I, Dror? Y, Giveon? SM, Gillis? ' 'D, Strich? D, Lavie? G. The link between vitamin D deficiency and ' 'COVID-19 in a large population? medRxiv. doi:10.1101/2020.09.04.20188268', 'DOI': '10.1101/2020.09.04.20188268'}, { 'key': 'zoi210150r17', 'unstructured': 'Centers for Disease Control and Prevention. CDC Diagnostic Tests for ' 'COVID-19. Accessed July 13, 2020. ' 'https://www.cdc.gov/coronavirus/2019-ncov/lab/testing.html'}, { 'key': 'zoi210150r18', 'unstructured': 'Eurofins Viracor. Coronavirus (COVID-19) SARS-CoV-2 RT-PCR. Accessed ' 'July 13, 2020. ' 'https://www.viracor-eurofins.com/test-menu/8300-coronavirus-covid-19-sars-cov-2-rt-pcr/'}, { 'key': 'zoi210150r19', 'unstructured': 'Roche Diagnostics. Cobas SARS-CoV-2 Test (for the COVID-19 coronavirus). ' 'Accessed July 13 2020. ' 'https://diagnostics.roche.com/us/en/products/params/cobas-sars-cov-2-test.html'}, { 'key': 'zoi210150r20', 'unstructured': 'Centers for Disease Control and Prevention. International Classification ' 'of Diseases, Tenth Revision, Clinical Modification (ICD-10-CM). Accessed ' 'February 15, 2021. https://www.cdc.gov/nchs/icd/icd10cm.htm'}, { 'key': 'zoi210150r24', 'unstructured': 'Pregibon? D. Data Analytic Methods for Generalized Linear Models. ' 'Dissertation. University of Toronto; 1979.'}, { 'key': 'zoi210150r43', 'unstructured': 'National Center for Immunization and Respiratory Diseases (NCIRD), ' 'Division of Viral Diseases. Preparing for COVID-19 in nursing homes. ' 'Accessed April 27, 2020. ' 'https://www.cdc.gov/coronavirus/2019-ncov/hcp/long-term-care.html'}, { 'key': 'zoi210150r48', 'unstructured': 'Frieden? T. Former CDC Chief Dr. Tom Frieden: coronavirus infection risk ' 'may be reduced by vitamin D. Fox News. March 23, 2020. Accessed April ' '13, 2020. ' 'https://www.foxnews.com/opinion/former-cdc-chief-tom-frieden-coronavirus-risk-may-be-reduced-with-vitamin-d'}, { 'key': 'zoi210150r49', 'unstructured': 'McCall? B. Medical societies advise on vitamin D in midst of COVID-19. ' 'Medscape Medical News. July 10, 2020. Accessed July 10, 2020. 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