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Antiviral activity of sulfated polysaccharides from marine algae and its application in combating COVID-19: Mini review

Hans et al., Bioresource Technology Reports, doi:10.1016/j.biteb.2020.100623
Dec 2020  
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Review of the antiviral activity of marine sulfated polysaccharides including carrageenan, and the mechanisms of action for inhibiting different stages of viral infection.
Reviews covering iota-carrageenan for COVID-19 include1-3.
Hans et al., 29 Dec 2020, peer-reviewed, 3 authors.
This PaperIota-carragee..All
Antiviral activity of sulfated polysaccharides from marine algae and its application in combating COVID-19: Mini review
Nidhi Hans, Anushree Malik, Satyanarayan Naik
Bioresource Technology Reports, doi:10.1016/j.biteb.2020.100623
Marine-derived sulfated polysaccharides possess various antiviral activities against a broad range of enveloped and non-enveloped viruses. It has become the potential source of antiviral drugs for pharmaceutical development. In this review, we will discuss the different types of sulfated polysaccharides and their structural classification. Some of the major sulfated polysaccharides with potent antiviral activity, including carrageenan, agar, ulvan, fucoidan, and alginates, are considered in this review. The mechanism of these sulfated polysaccharides in inhibiting the different stages of the viral infection process inside the host cell is also demonstrated. It involves blocking the initial entry of the virus or inhibiting its transcription and translation by modulating the immune response of the host cell. In addition, we explore the potential of sulfated polysaccharides as antiviral agents in preventing recent Corona Virus Disease-2019 (COVID-19).
Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
References
Aguilar-Briseño, Cruz-Suarez, Sassi, Ricque-Marie, Zapata-Benavides et al., Sulphated polysaccharides from Ulva clathrata and Cladosiphon okamuranus seaweeds both inhibit viral attachment/entry and cell-cell fusion, in NDV infection, Mar. Drugs, doi:10.3390/md13020697
Al-Alawi, Al-Marhubi, Al-Belushi, Soussi, Characterization of carrageenan extracted from Hypnea bryoides in Oman, Mar. Biotechnol, doi:10.1007/s10126-010-9350-7
Ale, Mikkelsen, Meyer, Review of structure-function relations and extraction methods for fucose-containing sulfated polysaccharides from brown seaweeds, Mar. Drugs
Bansal, Jonsson, Taylor, Figueroa, Dugour et al., Iota-carrageenan and xylitol inhibit SARS-CoV-2 in cell culture, BioRxiv, doi:10.1101/2020.08.19.225854
Bedoux, Caamal-Fuentes, Boulho, Marty, Bourgougnon et al., Antiviral and cytotoxic activities of polysaccharides extracted from four tropical seaweed species, Nat. Prod. Commun, doi:10.1177/1934578X1701200602
Besednova, Zvyagintseva, Kuznetsova, Makarenkova, Smolina et al., Marine algae metabolites as promising therapeutics for the prevention and treatment of HIV/ AIDS, Metabolites, doi:10.3390/metabo9050087
Bind, Goswami, Prakash, Comparative analysis of floating and submerged macrophytes for heavy metal (copper, chromium, arsenic and lead) removal: sorbent preparation, characterization, regeneration and cost estimation, Geol. Ecol. Landsc, doi:10.1080/24749508.2018.1452460
Bind, Kushwaha, Devi, Goswami, Sen et al., Biosorption valorization of floating and submerged macrophytes for heavy-metal removal in a multi-component system, Appl Water Sci, doi:10.1007/s13201-019-0976-y
Bjerregaard, Valderrama, Radulovich, Diana, Capron et al., Seaweed Aquaculture for Food Security, Income Generation and Environmental Health in Tropical Developing Countries
Bouhlal, Haslin, Chermann, Colliec-Jouault, Sinquin et al., Antiviral activities of sulfated polysaccharides isolated from Sphaerococcus coronopifolius (Rhodophytha, Gigartinales) and Boergeseniella thuyoides (Rhodophyta, Ceramiales), Mar. Drugs, doi:10.3390/md9071187
Buck, Thompson, Roberts, Müller, Lowy et al., Carrageenan is a potent inhibitor of papillomavirus infection, PLoS Pathog, doi:10.1371/journal.ppat.0020069
Carlucci, Scolaro, Damonte, Herpes simplex virus type 1 variants arising after selection with an antiviral carrageenan: lack of correlation between drug susceptibility and syn phenotype, J. Med. Virol, doi:10.1002/jmv.10174
Chen, Han, Wang, Zhao, Application prospect of polysaccharides in the development of anti-novel coronavirus drugs and vaccines, Int. J. Biol. Macromol, doi:10.1016/j.ijbiomac.2020.07.106
Chiu, Chan, Li, Wu, Inhibition of Japanese encephalitis virus infection by the sulfated polysaccharide extracts from Ulva lactuca, Mar. Biotechnol, doi:10.1007/s10126-011-9428-x
Chiu, Chan, Tsai, Li, Wu, Prevention of human enterovirus 71 infection by kappa carrageenan, Antivir. Res, doi:10.1016/j.antiviral.2012.05.009
Cirne-Santos, Barros, Nogueira, Azevedo, Yamomoto et al., Inhibition by marine algae of chikungunya virus isolated from patients in a recent disease outbreak in Rio de Janeiro, Front. Microbiol, doi:10.3389/fmicb.2019.02426
Dinesh, Menon, Hanna, Suresh, Sathuvan et al., In vitro anti-HIV-1 activity of fucoidan from Sargassum swartzii, Int. J. Biol. Macromol, doi:10.1016/j.ijbiomac.2015.09.078
Dutta, Kushwaha, Kalita, Devi, Bhuyan et al., Anticancer and cancer preventive properties of marine polysaccharides: some results and prospects, Bioresour. Technol. Rep, doi:10.3390/md11124876
Ferdouse, Holdt, Smith, Murúa, Yang, The global status of seaweed production, trade and utilization, Globefish Research Programme
Ferreira, Noseda, Gonçalves, Ducatti, Fujii et al., Chemical structure of the complex pyruvylated and sulfated agaran from the red seaweed Palisada flagellifera (Ceramiales, Rhodophyta), Carbohydr. Res, doi:10.1016/j.carres.2011.10.007
Figueira, Da Silva, Enrich-Prast, Yoneshigue-Valentin, De Oliveira, Structural characterization of ulvan polysaccharide from cultivated and collected Ulva fasciata (Chlorophyta), Adv. Biosci. Biotechnol, doi:10.4236/abb.2020.115016
Ghosh, Pujol, Damonte, Sinha, Ray, Sulfated xylomannans from the red seaweed Sebdenia polydactyla: structural features, chemical modification and antiviral activity, Antivir. Chem. Chemother, doi:10.1177/095632020901900603
Gomaa, Elshoubaky, Antiviral activity of sulfated polysaccharides carrageenan from some marine seaweeds, Int. J. Curr. Pharm. Rev. Res
Gonçalves, Ducatti, Duarte, Noseda, Sulfated and pyruvylated disaccharide alditols obtained from a red seaweed galactan: ESIMS and NMR approaches, Carbohydr. Res, doi:10.1016/S0008-6215(02)00318-X
Gorbalenya, Baker, Baric, Groot, Drosten et al., Severe acute respiratory syndrome-related coronavirus: the species and its viruses-a statement of the Coronavirus Study Group, doi:10.1101/2020.02.07.937862
Goswami, Kumar, Manikandan, Pakshirajan, Pugazhenthi, Anthracene biodegradation by Oleaginous Rhodococcus opacus for biodiesel production and its characterization, Polycycl. Aromat. Compd, doi:10.1080/10406638.2017.1302971
Goswami, Kumar, Pakshirajan, Pugazhenthi, A novel integrated biodegradation-microfiltration system for sustainable wastewater treatment and energy recovery, J. Hazard. Mater, doi:10.1016/j.jhazmat.2018.11.029
Goswami, Pakshirajan, Pugazhenthi, Biological treatment of biomass gasification wastewater using hydrocarbonoclastic bacterium Rhodococcus opacus in an up-flow packed bed bioreactor with a novel waste-derived nano-biochar based bio-support material, J. Clean. Prod, doi:10.1016/j.jclepro.2020.120253
Graf, Bernkop-Schnürch, Egyed, Koller, Prieschl-Grassauer et al., Development of a nasal spray containing xylometazoline hydrochloride and iota-carrageenan for the symptomatic relief of nasal congestion caused by rhinitis and sinusitis, Int. J. Gen. Med, doi:10.2147/IJGM.S167123
Grassauer, Prieschl-Grassauer, None, U.S. Patent No
Grassauer, Weinmuellner, Meier, Pretsch, Prieschl-Grassauer et al., Iota-Carrageenan is a potent inhibitor of rhinovirus infection, Virol. J, doi:10.1186/1743-422X-5-107
Güven, Coban, Özdemir, Pharmacology of marine macroalgae, Encycl. Mar. Biotechnol, doi:10.1002/9781119143802.ch20
Hans, Malik, Naik, Platform molecules from algae by using supercritical CO2 and subcritical water extraction, doi:10.1201/9780429054242
Hardouin, Bedoux, Burlot, Donnay-Moreno, Bergé et al., Enzyme-assisted extraction (EAE) for the production of antiviral and antioxidant extracts from the green seaweed Ulva armoricana (Ulvales, Ulvophyceae), Algal Res, doi:10.1016/j.algal.2016.03.013
Hayashi, Lee, Nakano, Hayashi, Anti-influenza A virus characteristics of a fucoidan from sporophyll of Undaria pinnatifida in mice with normal and compromised immunity, Microbes Infect, doi:10.1016/j.micinf.2012.12.004
Hemilä, Chalker, Carrageenan Nasal Spray May Double the Rate of Recovery From Coronavirus and Influenza Virus Infections: Re-analysis of Randomized Trial Data, doi:10.21203/rs.3.rs-108775/v1
Hemmingson, Falshaw, Furneaux, Thompson, Structure and antiviral activity of the galactofucan sulfates extracted from Undariapinnatifida (Phaeophyta), J. Appl. Phycol, doi:10.1007/s10811-006-9096-9
Hidari, Takahashi, Arihara, Nagaoka, Morita et al., Structure and anti-dengue virus activity of sulfated polysaccharide from a marine alga, Biochem. Biophys. Res. Commun, doi:10.1016/j.bbrc.2008.08.100
Jahan, Onay, Potentials of plant-based substance to inhabit and probable cure for the COVID-19, Turk. J. Biol, doi:10.3906/biy-2005-114
Jang, Shin, Lee, Kwon, Shin et al., Antiviral activity of lambda-carrageenan against influenza viruses in mice and severe acute respiratory syndrome coronavirus 2 in vitro, BioRxiv, doi:10.1101/2020.08.23.255364
Jiao, Yu, Zhang, Ewart, Chemical structures and bioactivities of sulfated polysaccharides from marine algae, Mar. Drugs, doi:10.3390/md9020196
Jo, Kim, Shin, Kim, Inhibition of SARS-CoV 3CL protease by flavonoids, J. Enzyme Inhib. Med. Chem, doi:10.1080/14756366.2019.1690480
Jönsson, Allahgholi, Sardari, Hreggviðsson, Nordberg Karlsson, Extraction and modification of macroalgal polysaccharides for current and next-generation applications, Molecules, doi:10.3390/molecules25040930
Khalid, Abbas, Saeed, Bader-Ul-Ain, Suleria, Therapeutic potential of seaweed bioactive compounds, Seaweed Biomater, doi:10.5772/intechopen.74060
Kidgell, Magnusson, De Nys, Glasson, Ulvan: a systematic review of extraction, composition and function, Algal Res, doi:10.1016/j.algal.2019.101422
Kim, Cho, Karnjanapratum, Shin, You, In vitro and in vivo immunomodulatory activity of sulfated polysaccharides from Enteromorpha prolifera, Int. J. Biol. Macromol, doi:10.1016/j.ijbiomac.2011.08.032
Koenighofer, Lion, Bodenteich, Prieschl-Grassauer, Grassauer et al., Carrageenan nasal spray in virus confirmed common cold: individual patient data analysis of two randomized controlled trials, Multidiscip. Respir. Med, doi:10.1186/2049-6958-9-57
Kushwaha, Rani, Kumar, Gautam, Heavy metal detoxification and tolerance mechanisms in plants: implications for phytoremediation, Environ. Rev, doi:10.1139/er-2015-0010
Kushwaha, Rani, Kumar, Mechanism of soil-metal-microbe interactions and their implication on microbial bioremediation and phytoremediation
Kushwaha, Rani, Patra, Adsorption kinetics and molecular interactions of lead [Pb (II)] with natural clay and humic acid, Int. J. Environ. Sci. Technol, doi:10.1007/s13762-019-02411-6
Kwon, Oh, Kwon, Jin, Zhang et al., Sulfated polysaccharides effectively inhibit SARS-CoV-2 in vitro, Cell Discov, doi:10.1038/s41421-020-00192-8
Lee, Hayashi, Maeda, Hayashi, Antiherpetic activities of sulfated polysaccharides from green algae, Planta Med, doi:10.1055/s-2004-827228
Lee, Kim, Seo, Park, Lee et al., Marine polysaccharides: therapeutic efficacy and biomedical applications, Arch. Pharm. Res, doi:10.1007/s12272-017-0958-2
Lee, Koizumi, Hayashi, Hayashi, Structure of rhamnan sulfate from the green alga Monostroma nitidum and its anti-herpetic effect, Carbohydr. Polym, doi:10.1016/j.carbpol.2010.03.014
Lee, Lim, Leow, Namasivayam, Abdullah et al., Biosynthesis of agar in red seaweeds: a review, Carbohydr. Polym, doi:10.1016/j.carbpol.2017.01.078
Lee, Takeshita, Hayashi, Hayashi, Structures and antiviral activities of polysaccharides from Sargassum trichophyllum, Carbohydr. Polym, doi:10.1016/j.carbpol.2011.05.059
Leibbrandt, Meier, König-Schuster, Weinmüllner, Kalthoff et al., Iota-carrageenan is a potent inhibitor of influenza a virus infection, PLoS One, doi:10.1371/journal.pone.0014320
Li, Mao, Hou, Gao, Qi et al., Preparation, structure and anticoagulant activity of a low molecular weight fraction produced by mild acid hydrolysis of sulfated rhamnan from Monostroma latissimum, Bioresour. Technol, doi:10.1016/j.biortech.2012.03.025
Liu, Gao, Yang, Meng, Zhan et al., Anti-cancer activity of porphyran and carrageenan from red seaweeds, Molecules, doi:10.3390/molecules24234286
Lopes, Ray, Espada, Bomfim, Ray et al., Green seaweed Enteromorpha compressa (Chlorophyta, Ulvaceae) derived sulphated polysaccharides inhibit herpes simplex virus, Int. J. Biol. Macromol, doi:10.1016/j.ijbiomac.2017.04.043
Makarenkova, Deriabin, L'vov, Zviagintseva, Besednova, Antiviral activity of sulfated polysaccharide from the brown algae Laminaria japonica against avian influenza A (H5N1) virus infection in the cultured cells, Vopr. Virusol
Malagoli, Cardozo, Gomes, Ferraz, Simões et al., Chemical characterization and antiherpes activity of sulfated polysaccharides from Lithothamnion muelleri, Int. J. Biol. Macromol, doi:10.1016/j.ijbiomac.2014.02.053
Mandal, Mateu, Chattopadhyay, Pujol, Damonte et al., Structural features and antiviral activity of sulphated fucans from the brown seaweed Cystoseira indica, Antivir. Chem. Chemother, doi:10.1177/095632020701800305
Mandal, Pujol, Carlucci, Chattopadhyay, Damonte et al., Anti-herpetic activity of a sulfated xylomannan from Scinaia hatei, Phytochemistry, doi:10.1016/j.phytochem.2008.05.004
Mazumder, Ghosal, Pujol, Carlucci, Damonte et al., Isolation, chemical investigation and antiviral activity of polysaccharides from Gracilaria corticata (Gracilariaceae, Rhodophyta), Int. J. Biol. Macromol, doi:10.1016/S0141-8130(02)00070-3
Mercer, Schelhaas, Helenius, Virus entry by endocytosis, Annu. Rev. Biochem, doi:10.1146/annurev-biochem-060208-104626
Morokutti-Kurz, Graf, Prieschl-Grassauer, Amylmetacresol/2, 4-dichlorobenzyl alcohol, hexylresorcinol, or carrageenan lozenges as active treatments for sore throat, Int. J. Gen. Med, doi:10.2147/IJGM.S120665
Morán-Santibañez, Cruz-Suárez, Ricque-Marie, Robledo, Freile-Pelegrín et al., Synergistic effects of sulfated polysaccharides from Mexican seaweeds against measles virus, Biomed. Res. Int, doi:10.1155/2016/8502123
Muthukumar, Chidambaram, Sukumaran, Sulfated polysaccharides and its commercial applications in food industries-a review, J. Food Sci. Technol, doi:10.1007/s13197-020-04837-0
Ortiz-Tena, Schieder, Sieber, Carrageenan and more: biorefinery approaches with special reference to the processing of Kappaphycus, doi:10.1007/978-3-319-63498-2_10
Ponce, Pujol, Damonte, Flores, Stortz, Fucoidans from the brown seaweed Adenocystis utricularis: extraction methods, antiviral activity and structural studies, Carbohydr. Res, doi:10.1016/S0008-6215(02)00403-2
Pujol, Estevez, Carlucci, Ciancia, Cerezo et al., Novel DL-galactan hybrids from the red seaweed Gymnogongrus torulosus are potent inhibitors of herpes simplex virus and dengue virus, Antivir. Chem. Chemother, doi:10.1177/095632020201300202
Queiroz, Medeiros, Queiroz, Abreu, Rocha et al., Inhibition of reverse transcriptase activity of HIV by polysaccharides of brown algae, Biomed. Pharmacother, doi:10.1016/j.biopha.2008.03.006
Rabanal, Ponce, Navarro, Gómez, Stortz, The system of fucoidans from the brown seaweed Dictyota dichotoma: chemical analysis and antiviral activity, Carbohydr. Polym, doi:10.1016/j.carbpol.2013.10.019
Ray, Polysaccharides from Enteromorpha compressa: isolation, purification and structural features, Carbohydr. Polym, doi:10.1016/j.carbpol.2006.03.027
Rhein-Knudsen, Ale, Meyer, Seaweed hydrocolloid production: an update on enzyme assisted extraction and modification technologies, Mar. Drugs, doi:10.3390/md13063340
Roy, Bhattacharyya, Possible role of traditional medicinal plant Neem (Azadirachta indica) for the management of COVID-19 infection, Int. J. Res. Pharm. Sci, doi:10.26452/ijrps.v11iSPL1.2256
Rudke, De Andrade, Ferreira, Kappaphycus alvarezii macroalgae: an unexplored and valuable biomass for green biorefinery conversion, Trends Food Sci. Technol, doi:10.1016/j.tifs.2020.07.018
Ruocco, Costantini, Guariniello, Costantini, Polysaccharides from the marine environment with pharmacological, cosmeceutical and nutraceutical potential, Molecules, doi:10.3390/molecules21050551
Sepúlveda-Crespo, Ceña-Díez, Jiménez, Ángeles Muñoz-Fernández, Mechanistic studies of viral entry: an overview of dendrimer-based microbicides as entry inhibitors against both HIV and HSV-2 overlapped infections, Med. Res. Rev, doi:10.1002/med.21405
Sf-Tischer, Talarico, Noseda, Guimarães, Damonte et al., Chemical structure and antiviral activity of carrageenans from Meristiella gelidium against herpes simplex and dengue virus, Carbohydr. Polym, doi:10.1016/j.carbpol.2005.09.020
Shree, Mishra, Selvaraj, Singh, Chaube et al., Targeting COVID-19 (SARS-CoV-2) main protease through active phytochemicals of ayurvedic medicinal plants-Withania somnifera (Ashwagandha), Tinospora cordifolia (Giloy) and Ocimum sanctum (Tulsi)-a molecular docking study, J. Biomol. Struct. Dyn, doi:10.1080/07391102.2020.1810778
Singh, Kushwaha, Hans, Gautam, Rani, Evaluation of the cytotoxicity and interaction of lead with lead resistant bacterium Acinetobacter junii Pb1, Braz. J. Microbiol, doi:10.1007/s42770-019-00041-1
Song, Peng, Wang, Liu, Dong et al., Inhibitory activities of marine sulfated polysaccharides against SARS-CoV-2, Food Funct, doi:10.1039/D0FO02017F
Sozzani, Bosisio, Scarsi, Tincani, Type I interferons in systemic autoimmunity, J. Autoimmun, doi:10.3109/08916930903510872
Talarico, Damonte, Interference in dengue virus adsorption and uncoating by carrageenans, Virology, doi:10.1016/j.virol.2007.01.043
Talarico, Zibetti, Faria, Scolaro, Duarte et al., Anti-herpes simplex virus activity of sulfated galactans from the red seaweeds Gymnogongrus griffithsiae and Cryptonemia crenulata, Int. J. Biol. Macromol, doi:10.1016/j.ijbiomac.2004.03.002
Tang, Chen, Li, Preparation and potential in vivo anti-influenza virus activity of low molecular-weight κ-carrageenans and their derivatives, J. Appl. Polym. Sci, doi:10.1002/app.37502
Thuy, Ly, Van, Quang, Tu et al., Anti-HIV activity of fucoidans from three brown seaweed species, Carbohydr. Polym, doi:10.1016/j.carbpol.2014.08.068
Trinchero, Ponce, Córdoba, Flores, Pampuro et al., Antiretroviral activity of fucoidans extracted from the brown seaweed Adenocystis utricularis, Phytother. Res, doi:10.1002/ptr.2723
Usov, Polysaccharides of the red algae, doi:10.1016/B978-0-12-385520-6.00004-2
Wahedi, Ahmad, Abbasi, Stilbene-based natural compounds as promising drug candidates against COVID-19, J. Biomol. Struct. Dyn, doi:10.1080/07391102.2020.1762743
Wang, Di, Ye, Wei, Study on the public psychological states and its related factors during the outbreak of coronavirus disease 2019 (COVID-19) in some regions of China, Psychol. Health Med, doi:10.1080/13548506.2020.1746817
Wang, Wang, Guan, The antiviral activities and mechanisms of marine polysaccharides: an overview, Mar. Drugs, doi:10.3390/md10122795
Wang, Wang, Hao, Yunjia, Qin et al., Antiviral activity against enterovirus 71 of sulfated rhamnan isolated from the green alga Monostroma latissimum, Carbohydr. Polym, doi:10.1016/j.carbpol.2018.07.067
Wang, Zhang, Hao, Zhang, Cui et al., In vitro inhibitory effect of carrageenan oligosaccharide on influenza A H1N1 virus, Antivir. Res, doi:10.1016/j.antiviral.2011.08.010
Wijesekara, Pangestuti, Kim, Biological activities and potential health benefits of sulfated polysaccharides derived from marine algae, Carbohydr. Polym, doi:10.1016/j.carbpol.2010.10.062
Worldometer, COVID-19 Coronavirus Pandemic
Xian, Zhang, Bian, Zhou, Zhang et al., Bioactive natural compounds against human coronaviruses: a review and perspective, Acta Pharm. Sin. B, doi:10.1016/j.apsb.2020.06.002
Xianliang, Hua, Meiyu, Pingfang, Yingxia et al., Studies of the anti-AIDS effects of marine polysaccharide drug 911 and its related mechanisms of action, Chin. J. Mar. Drugs
Xu, Chen, Wang, Feng, Zhou et al., Evolution of the novel coronavirus from the ongoing Wuhan outbreak and modeling of its spike protein for risk of human transmission, Sci. China Life Sci, doi:10.1007/s11427-020-1637-5
Yamada, Ogamo, Saito, Uchiyama, Nakagawa, Preparation of Oacylated low-molecular-weight carrageenans with potent anti-HIV activity and low anticoagulant effect, Carbohydr. Polym, doi:10.1016/S0144-8617(99)00083-1
Yu, Hu, Yang, Zhao, Wang et al., Extraction, isolation and structural characterization of polysaccharides from a red alga Gloiopeltis furcata, J. Ocean Univ. China, doi:10.1007/s11802-010-0193-7
Yuan, Song, Li, Li, Dai, Immunomodulation and antitumor activity of κ-carrageenan oligosaccharides, Cancer Lett, doi:10.1016/j.canlet.2005.11.032
Yuguchi, Bui, Takebe, Suzuki, Nakajima et al., Primary structure, conformation in aqueous solution, and intestinal immunomodulating activity of fucoidan from two brown seaweed species Sargassum crassifolium and Padina australis, Carbohydr. Polym, doi:10.1016/j.carbpol.2016.03.101
Zhang, Oda, Yu, Jin, Fucoidan from Macrocystis pyrifera has powerful immune-modulatory effects compared to three other fucoidans, Mar. Drugs, doi:10.3390/md13031084
Zhu, Ni, Sun, Zhu, Yin et al., Insight into carrageenases: major review of sources, category, property, purification method, structure, and applications, Crit. Rev. Biotechnol, doi:10.1080/07388551.2018.1472550
Zhu, Zhang, Wang, Li, Yang et al., A novel coronavirus from patients with pneumonia in China, N. Engl. J. Med, doi:10.1056/NEJMoa2001017
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Drugs'}, { 'key': '10.1016/j.biteb.2020.100623_bb0010', 'doi-asserted-by': 'crossref', 'first-page': '893', 'DOI': '10.1007/s10126-010-9350-7', 'article-title': 'Characterization of carrageenan extracted from Hypnea bryoides in Oman', 'volume': '13', 'author': 'Al-Alawi', 'year': '2011', 'journal-title': 'Mar. Biotechnol.'}, { 'key': '10.1016/j.biteb.2020.100623_bb0015', 'doi-asserted-by': 'crossref', 'first-page': '2106', 'DOI': '10.3390/md9102106', 'article-title': 'Review of structure-function relations and extraction methods for ' 'fucose-containing sulfated polysaccharides from brown seaweeds', 'volume': '9', 'author': 'Ale', 'year': '2011', 'journal-title': 'Mar. Drugs'}, { 'key': '10.1016/j.biteb.2020.100623_bb0020', 'unstructured': 'Allied market research, 2018. Seaweed Market by Product (Red, Brown, and ' 'Green) and Application (Human Food, Hydrocolloids, Fertilizers, Animal ' 'Feed Additives, and Others) - Global Opportunity Analysis and Industry ' 'Forecast. (Accessed 14 April 2020).'}, { 'key': '10.1016/j.biteb.2020.100623_bb0025', 'article-title': 'Iota-carrageenan and xylitol inhibit SARS-CoV-2 in cell culture', 'author': 'Bansal', 'year': '2020', 'journal-title': 'BioRxiv.'}, { 'issue': '6', 'key': '10.1016/j.biteb.2020.100623_bb0030', 'article-title': 'Antiviral and cytotoxic activities of polysaccharides extracted from ' 'four tropical seaweed species', 'volume': '12', 'author': 'Bedoux', 'year': '2017', 'journal-title': 'Nat. Prod. Commun.'}, { 'issue': '5', 'key': '10.1016/j.biteb.2020.100623_bb0035', 'doi-asserted-by': 'crossref', 'first-page': '87', 'DOI': '10.3390/metabo9050087', 'article-title': 'Marine algae metabolites as promising therapeutics for the prevention ' 'and treatment of HIV/AIDS', 'volume': '9', 'author': 'Besednova', 'year': '2019', 'journal-title': 'Metabolites.'}, { 'issue': '2', 'key': '10.1016/j.biteb.2020.100623_bb0040', 'doi-asserted-by': 'crossref', 'first-page': '61', 'DOI': '10.1080/24749508.2018.1452460', 'article-title': 'Comparative analysis of floating and submerged macrophytes for heavy ' 'metal (copper, chromium, arsenic and lead) removal: sorbent ' 'preparation, characterization, regeneration and cost estimation', 'volume': '2', 'author': 'Bind', 'year': '2018', 'journal-title': 'Geol. Ecol. Landsc.'}, { 'issue': '4', 'key': '10.1016/j.biteb.2020.100623_bb0045', 'doi-asserted-by': 'crossref', 'first-page': '95', 'DOI': '10.1007/s13201-019-0976-y', 'article-title': 'Biosorption valorization of floating and submerged macrophytes for ' 'heavy-metal removal in a multi-component system', 'volume': '9', 'author': 'Bind', 'year': '2019', 'journal-title': 'Appl Water Sci'}, { 'key': '10.1016/j.biteb.2020.100623_bb0050', 'series-title': 'Seaweed Aquaculture for Food Security, Income Generation and ' 'Environmental Health in Tropical Developing Countries', 'author': 'Bjerregaard', 'year': '2016'}, { 'issue': '7', 'key': '10.1016/j.biteb.2020.100623_bb0055', 'doi-asserted-by': 'crossref', 'first-page': '1187', 'DOI': '10.3390/md9071187', 'article-title': 'Antiviral activities of sulfated polysaccharides isolated from ' 'Sphaerococcus coronopifolius (Rhodophytha, Gigartinales) and ' 'Boergeseniella thuyoides (Rhodophyta, Ceramiales)', 'volume': '9', 'author': 'Bouhlal', 'year': '2011', 'journal-title': 'Mar. Drugs'}, { 'issue': '7', 'key': '10.1016/j.biteb.2020.100623_bb0060', 'doi-asserted-by': 'crossref', 'DOI': '10.1371/journal.ppat.0020069', 'article-title': 'Carrageenan is a potent inhibitor of papillomavirus infection', 'volume': '2', 'author': 'Buck', 'year': '2006', 'journal-title': 'PLoS Pathog.'}, { 'key': '10.1016/j.biteb.2020.100623_bb0065', 'doi-asserted-by': 'crossref', 'first-page': '92', 'DOI': '10.1002/jmv.10174', 'article-title': 'Herpes simplex virus type 1 variants arising after selection with an ' 'antiviral carrageenan: lack of correlation between drug susceptibility ' 'and syn phenotype', 'volume': '68', 'author': 'Carlucci', 'year': '2002', 'journal-title': 'J. Med. Virol.'}, { 'key': '10.1016/j.biteb.2020.100623_bb0070', 'doi-asserted-by': 'crossref', 'article-title': 'Application prospect of polysaccharides in the development of ' 'anti-novel coronavirus drugs and vaccines', 'author': 'Chen', 'year': '2020', 'journal-title': 'Int. J. Biol. Macromol.', 'DOI': '10.1016/j.ijbiomac.2020.07.106'}, { 'key': '10.1016/j.biteb.2020.100623_bb0075', 'doi-asserted-by': 'crossref', 'first-page': '468', 'DOI': '10.1007/s10126-011-9428-x', 'article-title': 'Inhibition of Japanese encephalitis virus infection by the sulfated ' 'polysaccharide extracts from Ulva lactuca', 'volume': '14', 'author': 'Chiu', 'year': '2012', 'journal-title': 'Mar. Biotechnol.'}, { 'key': '10.1016/j.biteb.2020.100623_bb0080', 'doi-asserted-by': 'crossref', 'first-page': '128', 'DOI': '10.1016/j.antiviral.2012.05.009', 'article-title': 'Prevention of human enterovirus 71 infection by kappa carrageenan', 'volume': '95', 'author': 'Chiu', 'year': '2012', 'journal-title': 'Antivir. Res.'}, { 'key': '10.1016/j.biteb.2020.100623_bb0085', 'doi-asserted-by': 'crossref', 'first-page': '2426', 'DOI': '10.3389/fmicb.2019.02426', 'article-title': 'Inhibition by marine algae of chikungunya virus isolated from patients ' 'in a recent disease outbreak in Rio de Janeiro', 'volume': '10', 'author': 'Cirne-Santos', 'year': '2019', 'journal-title': 'Front. Microbiol.'}, { 'key': '10.1016/j.biteb.2020.100623_bb0090', 'doi-asserted-by': 'crossref', 'first-page': '459', 'DOI': '10.1016/j.carbpol.2005.09.020', 'article-title': 'Chemical structure and antiviral activity of carrageenans from ' 'Meristiella gelidium against herpes simplex and dengue virus', 'volume': '63', 'author': 'De Sf-Tischer', 'year': '2006', 'journal-title': 'Carbohydr. Polym.'}, { 'key': '10.1016/j.biteb.2020.100623_bb0095', 'doi-asserted-by': 'crossref', 'first-page': '83', 'DOI': '10.1016/j.ijbiomac.2015.09.078', 'article-title': 'In vitro anti-HIV-1 activity of fucoidan from Sargassum swartzii', 'volume': '82', 'author': 'Dinesh', 'year': '2016', 'journal-title': 'Int. J. Biol. Macromol.'}, { 'key': '10.1016/j.biteb.2020.100623_bb0100', 'doi-asserted-by': 'crossref', 'first-page': '100242', 'DOI': '10.1016/j.biteb.2019.100242', 'article-title': 'Assessment of bioaccumulation and detoxification of cadmium in ' 'soil-plant-insect food chain', 'volume': '7', 'author': 'Dutta', 'year': '2019', 'journal-title': 'Bioresour. Technol. Rep.'}, { 'key': '10.1016/j.biteb.2020.100623_bb0105', 'unstructured': 'FAO., 2019. FAO yearbook. Fishery and Aquaculture Statistics 2017/FAO ' 'annuaire.'}, { 'key': '10.1016/j.biteb.2020.100623_bb0110', 'doi-asserted-by': 'crossref', 'first-page': '4876', 'DOI': '10.3390/md11124876', 'article-title': 'Anticancer and cancer preventive properties of marine polysaccharides: ' 'some results and prospects', 'volume': '11', 'author': 'Fedorov', 'year': '2013', 'journal-title': 'Mar. Drugs'}, { 'key': '10.1016/j.biteb.2020.100623_bb0115', 'unstructured': 'Ferdouse, F., Holdt, S. L., Smith, R., Murúa, P., & Yang, Z., 2018. The ' 'global status of seaweed production, trade and utilization. Globefish ' 'Research Programme. 124, I.'}, { 'key': '10.1016/j.biteb.2020.100623_bb0120', 'doi-asserted-by': 'crossref', 'first-page': '83', 'DOI': '10.1016/j.carres.2011.10.007', 'article-title': 'Chemical structure of the complex pyruvylated and sulfated agaran from ' 'the red seaweed Palisada flagellifera (Ceramiales, Rhodophyta)', 'volume': '347', 'author': 'Ferreira', 'year': '2012', 'journal-title': 'Carbohydr. Res.'}, { 'issue': '5', 'key': '10.1016/j.biteb.2020.100623_bb0125', 'doi-asserted-by': 'crossref', 'first-page': '206', 'DOI': '10.4236/abb.2020.115016', 'article-title': 'Structural characterization of ulvan polysaccharide from cultivated and ' 'collected Ulva fasciata (Chlorophyta)', 'volume': '11', 'author': 'Figueira', 'year': '2020', 'journal-title': 'Adv. Biosci. Biotechnol.'}, { 'key': '10.1016/j.biteb.2020.100623_bb0130', 'doi-asserted-by': 'crossref', 'first-page': '235', 'DOI': '10.1177/095632020901900603', 'article-title': 'Sulfated xylomannans from the red seaweed Sebdenia polydactyla: ' 'structural features, chemical modification and antiviral activity', 'volume': '19', 'author': 'Ghosh', 'year': '2009', 'journal-title': 'Antivir. Chem. Chemother.'}, { 'key': '10.1016/j.biteb.2020.100623_bb0135', 'first-page': '34', 'article-title': 'Antiviral activity of sulfated polysaccharides carrageenan from some ' 'marine seaweeds', 'volume': '7', 'author': 'Gomaa', 'year': '2016', 'journal-title': 'Int. J. Curr. Pharm. Rev. Res.'}, { 'key': '10.1016/j.biteb.2020.100623_bb0140', 'doi-asserted-by': 'crossref', 'first-page': '2443', 'DOI': '10.1016/S0008-6215(02)00318-X', 'article-title': 'Sulfated and pyruvylated disaccharide alditols obtained from a red ' 'seaweed galactan: ESIMS and NMR approaches', 'volume': '337', 'author': 'Gonçalves', 'year': '2002', 'journal-title': 'Carbohydr. Res.'}, { 'key': '10.1016/j.biteb.2020.100623_bb0145', 'article-title': 'Severe acute respiratory syndrome-related coronavirus: the species and ' 'its viruses–a statement of the Coronavirus Study Group', 'author': 'Gorbalenya', 'year': '2020', 'journal-title': 'BioRxiv.'}, { 'key': '10.1016/j.biteb.2020.100623_bb0150', 'doi-asserted-by': 'crossref', 'article-title': 'Anthracene biodegradation by Oleaginous Rhodococcus opacus for ' 'biodiesel production and its characterization', 'author': 'Goswami', 'year': '2019', 'journal-title': 'Polycycl. Aromat. Compd.', 'DOI': '10.1080/10406638.2017.1302971'}, { 'key': '10.1016/j.biteb.2020.100623_bb0155', 'doi-asserted-by': 'crossref', 'first-page': '707', 'DOI': '10.1016/j.jhazmat.2018.11.029', 'article-title': 'A novel integrated biodegradation—microfiltration system for ' 'sustainable wastewater treatment and energy recovery', 'volume': '365', 'author': 'Goswami', 'year': '2019', 'journal-title': 'J. Hazard. Mater.'}, { 'key': '10.1016/j.biteb.2020.100623_bb0160', 'doi-asserted-by': 'crossref', 'first-page': '120253', 'DOI': '10.1016/j.jclepro.2020.120253', 'article-title': 'Biological treatment of biomass gasification wastewater using ' 'hydrocarbonoclastic bacterium Rhodococcus opacus in an up-flow packed ' 'bed bioreactor with a novel waste-derived nano-biochar based ' 'bio-support material', 'volume': '256', 'author': 'Goswami', 'year': '2020', 'journal-title': 'J. Clean. Prod.'}, { 'key': '10.1016/j.biteb.2020.100623_bb0165', 'doi-asserted-by': 'crossref', 'first-page': '275', 'DOI': '10.2147/IJGM.S167123', 'article-title': 'Development of a nasal spray containing xylometazoline hydrochloride ' 'and iota-carrageenan for the symptomatic relief of nasal congestion ' 'caused by rhinitis and sinusitis', 'volume': '11', 'author': 'Graf', 'year': '2018', 'journal-title': 'Int. J. Gen. Med.'}, { 'key': '10.1016/j.biteb.2020.100623_bb0170', 'unstructured': 'Grassauer, A., & Prieschl-Grassauer, E., 2019. U.S. Patent No. ' '10,342,820. Washington, DC: U.S. Patent and Trademark Office.'}, { 'key': '10.1016/j.biteb.2020.100623_bb0175', 'doi-asserted-by': 'crossref', 'first-page': '107', 'DOI': '10.1186/1743-422X-5-107', 'article-title': 'Iota-Carrageenan is a potent inhibitor of rhinovirus infection', 'volume': '5', 'author': 'Grassauer', 'year': '2008', 'journal-title': 'Virol. J.'}, { 'key': '10.1016/j.biteb.2020.100623_bb0180', 'doi-asserted-by': 'crossref', 'first-page': '585', 'DOI': '10.1002/9781119143802.ch20', 'article-title': 'Pharmacology of marine macroalgae', 'volume': '1', 'author': 'Güven', 'year': '2020', 'journal-title': 'Encycl. Mar. Biotechnol.'}, { 'key': '10.1016/j.biteb.2020.100623_bb0185', 'series-title': 'Handbook of Algal Technologies and Phytochemicals: Volume I Food, Health ' 'and Nutraceutical Applications', 'article-title': 'Platform molecules from algae by using supercritical CO2 and ' 'subcritical water extraction', 'author': 'Hans', 'year': '2019'}, { 'key': '10.1016/j.biteb.2020.100623_bb0190', 'doi-asserted-by': 'crossref', 'first-page': '233', 'DOI': '10.1016/j.algal.2016.03.013', 'article-title': 'Enzyme-assisted extraction (EAE) for the production of antiviral and ' 'antioxidant extracts from the green seaweed Ulva armoricana (Ulvales, ' 'Ulvophyceae)', 'volume': '16', 'author': 'Hardouin', 'year': '2016', 'journal-title': 'Algal Res.'}, { 'key': '10.1016/j.biteb.2020.100623_bb0195', 'doi-asserted-by': 'crossref', 'first-page': '302', 'DOI': '10.1016/j.micinf.2012.12.004', 'article-title': 'Anti-influenza A virus characteristics of a fucoidan from sporophyll of ' 'Undaria pinnatifida in mice with normal and compromised immunity', 'volume': '15', 'author': 'Hayashi', 'year': '2013', 'journal-title': 'Microbes Infect.'}, { 'key': '10.1016/j.biteb.2020.100623_bb0200', 'series-title': 'Carrageenan Nasal Spray May Double the Rate of Recovery From Coronavirus ' 'and Influenza Virus Infections: Re-analysis of Randomized Trial Data', 'author': 'Hemilä', 'year': '2020'}, { 'key': '10.1016/j.biteb.2020.100623_bb0205', 'doi-asserted-by': 'crossref', 'first-page': '185', 'DOI': '10.1007/s10811-006-9096-9', 'article-title': 'Structure and antiviral activity of the galactofucan sulfates extracted ' 'from Undariapinnatifida (Phaeophyta)', 'volume': '18', 'author': 'Hemmingson', 'year': '2006', 'journal-title': 'J. Appl. Phycol.'}, { 'key': '10.1016/j.biteb.2020.100623_bb0210', 'doi-asserted-by': 'crossref', 'first-page': '91', 'DOI': '10.1016/j.bbrc.2008.08.100', 'article-title': 'Structure and anti-dengue virus activity of sulfated polysaccharide ' 'from a marine alga', 'volume': '376', 'author': 'Hidari', 'year': '2008', 'journal-title': 'Biochem. Biophys. Res. Commun.'}, { 'issue': '3', 'key': '10.1016/j.biteb.2020.100623_bb0215', 'doi-asserted-by': 'crossref', 'first-page': '228', 'DOI': '10.3906/biy-2005-114', 'article-title': 'Potentials of plant-based substance to inhabit and probable cure for ' 'the COVID-19', 'volume': '44', 'author': 'Jahan', 'year': '2020', 'journal-title': 'Turk. J. Biol.'}, { 'key': '10.1016/j.biteb.2020.100623_bb0220', 'article-title': 'Antiviral activity of lambda-carrageenan against influenza viruses in ' 'mice and severe acute respiratory syndrome coronavirus 2 in vitro', 'author': 'Jang', 'year': '2020', 'journal-title': 'BioRxiv.'}, { 'key': '10.1016/j.biteb.2020.100623_bb0225', 'doi-asserted-by': 'crossref', 'first-page': '196', 'DOI': '10.3390/md9020196', 'article-title': 'Chemical structures and bioactivities of sulfated polysaccharides from ' 'marine algae', 'volume': '9', 'author': 'Jiao', 'year': '2011', 'journal-title': 'Mar. Drugs'}, { 'issue': '1', 'key': '10.1016/j.biteb.2020.100623_bb0230', 'doi-asserted-by': 'crossref', 'first-page': '145', 'DOI': '10.1080/14756366.2019.1690480', 'article-title': 'Inhibition of SARS-CoV 3CL protease by flavonoids', 'volume': '35', 'author': 'Jo', 'year': '2020', 'journal-title': 'J. Enzyme Inhib. Med. Chem.'}, { 'issue': '4', 'key': '10.1016/j.biteb.2020.100623_bb0235', 'doi-asserted-by': 'crossref', 'first-page': '930', 'DOI': '10.3390/molecules25040930', 'article-title': 'Extraction and modification of macroalgal polysaccharides for current ' 'and next-generation applications', 'volume': '25', 'author': 'Jönsson', 'year': '2020', 'journal-title': 'Molecules.'}, { 'key': '10.1016/j.biteb.2020.100623_bb0240', 'first-page': '7', 'article-title': 'Therapeutic potential of seaweed bioactive compounds', 'volume': '1', 'author': 'Khalid', 'year': '2018', 'journal-title': 'Seaweed Biomater.'}, { 'key': '10.1016/j.biteb.2020.100623_bb0245', 'doi-asserted-by': 'crossref', 'first-page': '101422', 'DOI': '10.1016/j.algal.2019.101422', 'article-title': 'Ulvan: a systematic review of extraction, composition and function', 'volume': '39', 'author': 'Kidgell', 'year': '2019', 'journal-title': 'Algal Res.'}, { 'key': '10.1016/j.biteb.2020.100623_bb0250', 'doi-asserted-by': 'crossref', 'first-page': '1051', 'DOI': '10.1016/j.ijbiomac.2011.08.032', 'article-title': 'In vitro and in vivo immunomodulatory activity of sulfated ' 'polysaccharides from Enteromorpha prolifera', 'volume': '49', 'author': 'Kim', 'year': '2011', 'journal-title': 'Int. J. Biol. Macromol.'}, { 'key': '10.1016/j.biteb.2020.100623_bb0255', 'series-title': 'Springer Handbook of Marine Biotechnology', 'year': '2015'}, { 'key': '10.1016/j.biteb.2020.100623_bb0260', 'doi-asserted-by': 'crossref', 'first-page': '57', 'DOI': '10.1186/2049-6958-9-57', 'article-title': 'Carrageenan nasal spray in virus confirmed common cold: individual ' 'patient data analysis of two randomized controlled trials', 'volume': '9', 'author': 'Koenighofer', 'year': '2014', 'journal-title': 'Multidiscip. Respir. Med.'}, { 'issue': '1', 'key': '10.1016/j.biteb.2020.100623_bb0265', 'doi-asserted-by': 'crossref', 'first-page': '39', 'DOI': '10.1139/er-2015-0010', 'article-title': 'Heavy metal detoxification and tolerance mechanisms in plants: ' 'implications for phytoremediation', 'volume': '24', 'author': 'Kushwaha', 'year': '2015', 'journal-title': 'Environ. Rev.'}, { 'key': '10.1016/j.biteb.2020.100623_bb0270', 'series-title': 'Environmental Science and Engineering, 8', 'first-page': '462', 'article-title': 'Mechanism of soil-metal-microbe interactions and their implication on ' 'microbial bioremediation and phytoremediation', 'author': 'Kushwaha', 'year': '2017'}, { 'issue': '3', 'key': '10.1016/j.biteb.2020.100623_bb0275', 'doi-asserted-by': 'crossref', 'first-page': '1325', 'DOI': '10.1007/s13762-019-02411-6', 'article-title': 'Adsorption kinetics and molecular interactions of lead [Pb (II)] with ' 'natural clay and humic acid', 'volume': '17', 'author': 'Kushwaha', 'year': '2020', 'journal-title': 'Int. J. Environ. Sci. Technol.'}, { 'issue': '1', 'key': '10.1016/j.biteb.2020.100623_bb0280', 'doi-asserted-by': 'crossref', 'first-page': '1', 'DOI': '10.1038/s41421-020-00192-8', 'article-title': 'Sulfated polysaccharides effectively inhibit SARS-CoV-2 in vitro', 'volume': '6', 'author': 'Kwon', 'year': '2020', 'journal-title': 'Cell Discov.'}, { 'key': '10.1016/j.biteb.2020.100623_bb0285', 'doi-asserted-by': 'crossref', 'first-page': '813', 'DOI': '10.1055/s-2004-827228', 'article-title': 'Antiherpetic activities of sulfated polysaccharides from green algae', 'volume': '70', 'author': 'Lee', 'year': '2004', 'journal-title': 'Planta Med.'}, { 'key': '10.1016/j.biteb.2020.100623_bb0290', 'doi-asserted-by': 'crossref', 'first-page': '572', 'DOI': '10.1016/j.carbpol.2010.03.014', 'article-title': 'Structure of rhamnan sulfate from the green alga Monostroma nitidum and ' 'its anti-herpetic effect', 'volume': '81', 'author': 'Lee', 'year': '2010', 'journal-title': 'Carbohydr. Polym.'}, { 'key': '10.1016/j.biteb.2020.100623_bb0295', 'doi-asserted-by': 'crossref', 'first-page': '995', 'DOI': '10.1016/j.carbpol.2011.05.059', 'article-title': 'Structures and antiviral activities of polysaccharides from Sargassum ' 'trichophyllum', 'volume': '86', 'author': 'Lee', 'year': '2011', 'journal-title': 'Carbohydr. Polym.'}, { 'key': '10.1016/j.biteb.2020.100623_bb0300', 'doi-asserted-by': 'crossref', 'first-page': '23', 'DOI': '10.1016/j.carbpol.2017.01.078', 'article-title': 'Biosynthesis of agar in red seaweeds: a review', 'volume': '164', 'author': 'Lee', 'year': '2017', 'journal-title': 'Carbohydr. Polym.'}, { 'issue': '9', 'key': '10.1016/j.biteb.2020.100623_bb0305', 'doi-asserted-by': 'crossref', 'first-page': '1006', 'DOI': '10.1007/s12272-017-0958-2', 'article-title': 'Marine polysaccharides: therapeutic efficacy and biomedical ' 'applications', 'volume': '40', 'author': 'Lee', 'year': '2017', 'journal-title': 'Arch. Pharm. Res.'}, { 'issue': '12', 'key': '10.1016/j.biteb.2020.100623_bb0310', 'doi-asserted-by': 'crossref', 'DOI': '10.1371/journal.pone.0014320', 'article-title': 'Iota-carrageenan is a potent inhibitor of influenza a virus infection', 'volume': '5', 'author': 'Leibbrandt', 'year': '2010', 'journal-title': 'PLoS One'}, { 'key': '10.1016/j.biteb.2020.100623_bb0315', 'doi-asserted-by': 'crossref', 'first-page': '414', 'DOI': '10.1016/j.biortech.2012.03.025', 'article-title': 'Preparation, structure and anticoagulant activity of a low molecular ' 'weight fraction produced by mild acid hydrolysis of sulfated rhamnan ' 'from Monostroma latissimum', 'volume': '114', 'author': 'Li', 'year': '2012', 'journal-title': 'Bioresour. Technol.'}, { 'issue': '23', 'key': '10.1016/j.biteb.2020.100623_bb0320', 'doi-asserted-by': 'crossref', 'first-page': '4286', 'DOI': '10.3390/molecules24234286', 'article-title': 'Anti-cancer activity of porphyran and carrageenan from red seaweeds', 'volume': '24', 'author': 'Liu', 'year': '2019', 'journal-title': 'Molecules'}, { 'key': '10.1016/j.biteb.2020.100623_bb0325', 'doi-asserted-by': 'crossref', 'first-page': '605', 'DOI': '10.1016/j.ijbiomac.2017.04.043', 'article-title': 'Green seaweed Enteromorpha compressa (Chlorophyta, Ulvaceae) derived ' 'sulphated polysaccharides inhibit herpes simplex virus', 'volume': '102', 'author': 'Lopes', 'year': '2017', 'journal-title': 'Int. J. Biol. Macromol.'}, { 'key': '10.1016/j.biteb.2020.100623_bb0330', 'first-page': '41', 'article-title': 'Antiviral activity of sulfated polysaccharide from the brown algae ' 'Laminaria japonica against avian influenza A (H5N1) virus infection in ' 'the cultured cells', 'volume': '55', 'author': 'Makarenkova', 'year': '2010', 'journal-title': 'Vopr. Virusol.'}, { 'key': '10.1016/j.biteb.2020.100623_bb0335', 'doi-asserted-by': 'crossref', 'first-page': '332', 'DOI': '10.1016/j.ijbiomac.2014.02.053', 'article-title': 'Chemical characterization and antiherpes activity of sulfated ' 'polysaccharides from Lithothamnion muelleri', 'volume': '66', 'author': 'Malagoli', 'year': '2014', 'journal-title': 'Int. J. Biol. Macromol.'}, { 'key': '10.1016/j.biteb.2020.100623_bb0340', 'doi-asserted-by': 'crossref', 'first-page': '153', 'DOI': '10.1177/095632020701800305', 'article-title': 'Structural features and antiviral activity of sulphated fucans from the ' 'brown seaweed Cystoseira indica', 'volume': '18', 'author': 'Mandal', 'year': '2007', 'journal-title': 'Antivir. Chem. Chemother.'}, { 'key': '10.1016/j.biteb.2020.100623_bb0345', 'doi-asserted-by': 'crossref', 'first-page': '2193', 'DOI': '10.1016/j.phytochem.2008.05.004', 'article-title': 'Anti-herpetic activity of a sulfated xylomannan from Scinaia hatei', 'volume': '69', 'author': 'Mandal', 'year': '2008', 'journal-title': 'Phytochemistry.'}, { 'key': '10.1016/j.biteb.2020.100623_bb0350', 'doi-asserted-by': 'crossref', 'first-page': '87', 'DOI': '10.1016/S0141-8130(02)00070-3', 'article-title': 'Isolation, chemical investigation and antiviral activity of ' 'polysaccharides from Gracilaria corticata (Gracilariaceae, Rhodophyta)', 'volume': '31', 'author': 'Mazumder', 'year': '2002', 'journal-title': 'Int. J. Biol. Macromol.'}, { 'key': '10.1016/j.biteb.2020.100623_bb0355', 'doi-asserted-by': 'crossref', 'first-page': '803', 'DOI': '10.1146/annurev-biochem-060208-104626', 'article-title': 'Virus entry by endocytosis', 'volume': '79', 'author': 'Mercer', 'year': '2010', 'journal-title': 'Annu. Rev. Biochem.'}, { 'key': '10.1016/j.biteb.2020.100623_bb0360', 'first-page': '2016', 'article-title': 'Synergistic effects of sulfated polysaccharides from Mexican seaweeds ' 'against measles virus', 'author': 'Morán-Santibañez', 'year': '2016', 'journal-title': 'Biomed. Res. Int.'}, { 'key': '10.1016/j.biteb.2020.100623_bb0365', 'doi-asserted-by': 'crossref', 'first-page': '53', 'DOI': '10.2147/IJGM.S120665', 'article-title': 'Amylmetacresol/2, 4-dichlorobenzyl alcohol, hexylresorcinol, or ' 'carrageenan lozenges as active treatments for sore throat', 'volume': '10', 'author': 'Morokutti-Kurz', 'year': '2017', 'journal-title': 'Int. J. Gen. Med.'}, { 'key': '10.1016/j.biteb.2020.100623_bb0370', 'first-page': '1', 'article-title': 'Sulfated polysaccharides and its commercial applications in food ' 'industries—a review', 'author': 'Muthukumar', 'year': '2020', 'journal-title': 'J. Food Sci. Technol.'}, { 'key': '10.1016/j.biteb.2020.100623_bb0375', 'series-title': 'Tropical Seaweed Farming Trends, Problems and Opportunities', 'first-page': '155', 'article-title': 'Carrageenan and more: biorefinery approaches with special reference to ' 'the processing of Kappaphycus', 'volume': 'vol. 9', 'author': 'Ortiz-Tena', 'year': '2017'}, { 'key': '10.1016/j.biteb.2020.100623_bb0380', 'doi-asserted-by': 'crossref', 'first-page': '153', 'DOI': '10.1016/S0008-6215(02)00403-2', 'article-title': 'Fucoidans from the brown seaweed Adenocystis utricularis: extraction ' 'methods, antiviral activity and structural studies', 'volume': '338', 'author': 'Ponce', 'year': '2003', 'journal-title': 'Carbohydr. Res.'}, { 'key': '10.1016/j.biteb.2020.100623_bb0385', 'doi-asserted-by': 'crossref', 'first-page': '83', 'DOI': '10.1177/095632020201300202', 'article-title': 'Novel DL-galactan hybrids from the red seaweed Gymnogongrus torulosus ' 'are potent inhibitors of herpes simplex virus and dengue virus', 'volume': '13', 'author': 'Pujol', 'year': '2002', 'journal-title': 'Antivir. Chem. Chemother.'}, { 'key': '10.1016/j.biteb.2020.100623_bb0390', 'doi-asserted-by': 'crossref', 'first-page': '303', 'DOI': '10.1016/j.biopha.2008.03.006', 'article-title': 'Inhibition of reverse transcriptase activity of HIV by polysaccharides ' 'of brown algae', 'volume': '62', 'author': 'Queiroz', 'year': '2008', 'journal-title': 'Biomed. Pharmacother.'}, { 'key': '10.1016/j.biteb.2020.100623_bb0395', 'doi-asserted-by': 'crossref', 'first-page': '804', 'DOI': '10.1016/j.carbpol.2013.10.019', 'article-title': 'The system of fucoidans from the brown seaweed Dictyota dichotoma: ' 'chemical analysis and antiviral activity', 'volume': '101', 'author': 'Rabanal', 'year': '2014', 'journal-title': 'Carbohydr. Polym.'}, { 'key': '10.1016/j.biteb.2020.100623_bb0400', 'doi-asserted-by': 'crossref', 'first-page': '408', 'DOI': '10.1016/j.carbpol.2006.03.027', 'article-title': 'Polysaccharides from Enteromorpha compressa: isolation, purification ' 'and structural features', 'volume': '66', 'author': 'Ray', 'year': '2006', 'journal-title': 'Carbohydr. Polym.'}, { 'key': '10.1016/j.biteb.2020.100623_bb0405', 'doi-asserted-by': 'crossref', 'first-page': '3340', 'DOI': '10.3390/md13063340', 'article-title': 'Seaweed hydrocolloid production: an update on enzyme assisted ' 'extraction and modification technologies', 'volume': '13', 'author': 'Rhein-Knudsen', 'year': '2015', 'journal-title': 'Mar. Drugs'}, { 'key': '10.1016/j.biteb.2020.100623_bb0410', 'doi-asserted-by': 'crossref', 'first-page': '122', 'DOI': '10.26452/ijrps.v11iSPL1.2256', 'article-title': 'Possible role of traditional medicinal plant Neem (Azadirachta indica) ' 'for the management of COVID-19 infection', 'volume': '11', 'author': 'Roy', 'year': '2020', 'journal-title': 'Int. J. Res. Pharm. Sci.'}, { 'key': '10.1016/j.biteb.2020.100623_bb0415', 'doi-asserted-by': 'crossref', 'first-page': '214', 'DOI': '10.1016/j.tifs.2020.07.018', 'article-title': 'Kappaphycus alvarezii macroalgae: an unexplored and valuable biomass ' 'for green biorefinery conversion', 'volume': '103', 'author': 'Rudke', 'year': '2020', 'journal-title': 'Trends Food Sci. Technol.'}, { 'issue': '5', 'key': '10.1016/j.biteb.2020.100623_bb0420', 'doi-asserted-by': 'crossref', 'first-page': '551', 'DOI': '10.3390/molecules21050551', 'article-title': 'Polysaccharides from the marine environment with pharmacological, ' 'cosmeceutical and nutraceutical potential', 'volume': '21', 'author': 'Ruocco', 'year': '2016', 'journal-title': 'Molecules.'}, { 'issue': '1', 'key': '10.1016/j.biteb.2020.100623_bb0425', 'doi-asserted-by': 'crossref', 'first-page': '149', 'DOI': '10.1002/med.21405', 'article-title': 'Mechanistic studies of viral entry: an overview of dendrimer-based ' 'microbicides as entry inhibitors against both HIV and HSV-2 overlapped ' 'infections', 'volume': '37', 'author': 'Sepúlveda-Crespo', 'year': '2017', 'journal-title': 'Med. Res. Rev.'}, { 'key': '10.1016/j.biteb.2020.100623_bb0430', 'article-title': 'Targeting COVID-19 (SARS-CoV-2) main protease through active ' 'phytochemicals of ayurvedic medicinal plants–Withania somnifera ' '(Ashwagandha), Tinospora cordifolia (Giloy) and Ocimum sanctum ' '(Tulsi)–a molecular docking study', 'volume': '1-14', 'author': 'Shree', 'year': '2020', 'journal-title': 'J. Biomol. Struct. Dyn.'}, { 'issue': '1', 'key': '10.1016/j.biteb.2020.100623_bb0435', 'doi-asserted-by': 'crossref', 'first-page': '223', 'DOI': '10.1007/s42770-019-00041-1', 'article-title': 'Evaluation of the cytotoxicity and interaction of lead with lead ' 'resistant bacterium Acinetobacter junii Pb1', 'volume': '50', 'author': 'Singh', 'year': '2019', 'journal-title': 'Braz. J. Microbiol.'}, { 'issue': '9', 'key': '10.1016/j.biteb.2020.100623_bb0440', 'doi-asserted-by': 'crossref', 'first-page': '7415', 'DOI': '10.1039/D0FO02017F', 'article-title': 'Inhibitory activities of marine sulfated polysaccharides against ' 'SARS-CoV-2', 'volume': '11', 'author': 'Song', 'year': '2020', 'journal-title': 'Food Funct.'}, { 'key': '10.1016/j.biteb.2020.100623_bb0445', 'doi-asserted-by': 'crossref', 'first-page': '196', 'DOI': '10.3109/08916930903510872', 'article-title': 'Type I interferons in systemic autoimmunity', 'volume': '43', 'author': 'Sozzani', 'year': '2010', 'journal-title': 'J. Autoimmun.'}, { 'key': '10.1016/j.biteb.2020.100623_bb0450', 'doi-asserted-by': 'crossref', 'first-page': '473', 'DOI': '10.1016/j.virol.2007.01.043', 'article-title': 'Interference in dengue virus adsorption and uncoating by carrageenans', 'volume': '363', 'author': 'Talarico', 'year': '2007', 'journal-title': 'Virology.'}, { 'key': '10.1016/j.biteb.2020.100623_bb0455', 'doi-asserted-by': 'crossref', 'first-page': '63', 'DOI': '10.1016/j.ijbiomac.2004.03.002', 'article-title': 'Anti-herpes simplex virus activity of sulfated galactans from the red ' 'seaweeds Gymnogongrus griffithsiae and Cryptonemia crenulata', 'volume': '34', 'author': 'Talarico', 'year': '2004', 'journal-title': 'Int. J. Biol. Macromol.'}, { 'key': '10.1016/j.biteb.2020.100623_bb0460', 'doi-asserted-by': 'crossref', 'first-page': '2110', 'DOI': '10.1002/app.37502', 'article-title': 'Preparation and potential in vivo anti-influenza virus activity of low ' 'molecular-weight κ-carrageenans and their derivatives', 'volume': '127', 'author': 'Tang', 'year': '2013', 'journal-title': 'J. Appl. Polym. Sci.'}, { 'key': '10.1016/j.biteb.2020.100623_bb0465', 'doi-asserted-by': 'crossref', 'first-page': '122', 'DOI': '10.1016/j.carbpol.2014.08.068', 'article-title': 'Anti-HIV activity of fucoidans from three brown seaweed species', 'volume': '115', 'author': 'Thuy', 'year': '2015', 'journal-title': 'Carbohydr. Polym.'}, { 'key': '10.1016/j.biteb.2020.100623_bb0470', 'doi-asserted-by': 'crossref', 'first-page': '707', 'DOI': '10.1002/ptr.2723', 'article-title': 'Antiretroviral activity of fucoidans extracted from the brown seaweed ' 'Adenocystis utricularis', 'volume': '23', 'author': 'Trinchero', 'year': '2009', 'journal-title': 'Phytother. Res.'}, { 'key': '10.1016/j.biteb.2020.100623_bb0475', 'series-title': 'Advances in Carbohydrate Chemistry and Biochemistry', 'doi-asserted-by': 'crossref', 'first-page': '115', 'DOI': '10.1016/B978-0-12-385520-6.00004-2', 'article-title': 'Polysaccharides of the red algae', 'author': 'Usov', 'year': '2011'}, { 'key': '10.1016/j.biteb.2020.100623_bb0480', 'article-title': 'Stilbene-based natural compounds as promising drug candidates against ' 'COVID-19', 'volume': '1-10', 'author': 'Wahedi', 'year': '2020', 'journal-title': 'J. Biomol. Struct. Dyn.'}, { 'key': '10.1016/j.biteb.2020.100623_bb0485', 'doi-asserted-by': 'crossref', 'first-page': '43', 'DOI': '10.1016/j.carbpol.2018.07.067', 'article-title': 'Antiviral activity against enterovirus 71 of sulfated rhamnan isolated ' 'from the green alga Monostroma latissimum', 'volume': '200', 'author': 'Wang', 'year': '2018', 'journal-title': 'Carbohydr. Polym.'}, { 'key': '10.1016/j.biteb.2020.100623_bb0490', 'doi-asserted-by': 'crossref', 'first-page': '237', 'DOI': '10.1016/j.antiviral.2011.08.010', 'article-title': 'In vitro inhibitory effect of carrageenan oligosaccharide on influenza ' 'A H1N1 virus', 'volume': '92', 'author': 'Wang', 'year': '2011', 'journal-title': 'Antivir. Res.'}, { 'key': '10.1016/j.biteb.2020.100623_bb0495', 'doi-asserted-by': 'crossref', 'first-page': '2795', 'DOI': '10.3390/md10122795', 'article-title': 'The antiviral activities and mechanisms of marine polysaccharides: an ' 'overview', 'volume': '10', 'author': 'Wang', 'year': '2012', 'journal-title': 'Mar. Drugs'}, { 'key': '10.1016/j.biteb.2020.100623_bb0500', 'first-page': '1', 'article-title': 'Study on the public psychological states and its related factors during ' 'the outbreak of coronavirus disease 2019 (COVID-19) in some regions of ' 'China', 'author': 'Wang', 'year': '2020', 'journal-title': 'Psychol. Health Med.'}, { 'key': '10.1016/j.biteb.2020.100623_bb0505', 'doi-asserted-by': 'crossref', 'first-page': '14', 'DOI': '10.1016/j.carbpol.2010.10.062', 'article-title': 'Biological activities and potential health benefits of sulfated ' 'polysaccharides derived from marine algae', 'volume': '84', 'author': 'Wijesekara', 'year': '2011', 'journal-title': 'Carbohydr. Polym.'}, { 'key': '10.1016/j.biteb.2020.100623_bb0510', 'unstructured': 'Worldometer [Internet] COVID-19 Coronavirus Pandemic., 2020. Available ' 'from: https://www.worldometers.info/coronavirus/ (Accessed 20 November ' '2020).'}, { 'key': '10.1016/j.biteb.2020.100623_bb0515', 'doi-asserted-by': 'crossref', 'first-page': '1163', 'DOI': '10.1016/j.apsb.2020.06.002', 'article-title': 'Bioactive natural compounds against human coronaviruses: a review and ' 'perspective', 'volume': '10', 'author': 'Xian', 'year': '2020', 'journal-title': 'Acta Pharm. Sin. B'}, { 'issue': '6', 'key': '10.1016/j.biteb.2020.100623_bb0520', 'first-page': '4', 'article-title': 'Studies of the anti-AIDS effects of marine polysaccharide drug 911 and ' 'its related mechanisms of action', 'volume': '19', 'author': 'Xianliang', 'year': '2000', 'journal-title': 'Chin. J. Mar. Drugs'}, { 'key': '10.1016/j.biteb.2020.100623_bb0525', 'doi-asserted-by': 'crossref', 'first-page': '457', 'DOI': '10.1007/s11427-020-1637-5', 'article-title': 'Evolution of the novel coronavirus from the ongoing Wuhan outbreak and ' 'modeling of its spike protein for risk of human transmission', 'volume': '63', 'author': 'Xu', 'year': '2020', 'journal-title': 'Sci. China Life Sci.'}, { 'key': '10.1016/j.biteb.2020.100623_bb0530', 'doi-asserted-by': 'crossref', 'first-page': '115', 'DOI': '10.1016/S0144-8617(99)00083-1', 'article-title': 'Preparation of O-acylated low-molecular-weight carrageenans with potent ' 'anti-HIV activity and low anticoagulant effect', 'volume': '41', 'author': 'Yamada', 'year': '2000', 'journal-title': 'Carbohydr. Polym.'}, { 'key': '10.1016/j.biteb.2020.100623_bb0535', 'doi-asserted-by': 'crossref', 'first-page': '193', 'DOI': '10.1007/s11802-010-0193-7', 'article-title': 'Extraction, isolation and structural characterization of ' 'polysaccharides from a red alga Gloiopeltis furcata', 'volume': '9', 'author': 'Yu', 'year': '2010', 'journal-title': 'J. Ocean Univ. China'}, { 'key': '10.1016/j.biteb.2020.100623_bb0540', 'doi-asserted-by': 'crossref', 'first-page': '228', 'DOI': '10.1016/j.canlet.2005.11.032', 'article-title': 'Immunomodulation and antitumor activity of κ-carrageenan ' 'oligosaccharides', 'volume': '243', 'author': 'Yuan', 'year': '2006', 'journal-title': 'Cancer Lett.'}, { 'key': '10.1016/j.biteb.2020.100623_bb0545', 'doi-asserted-by': 'crossref', 'first-page': '69', 'DOI': '10.1016/j.carbpol.2016.03.101', 'article-title': 'Primary structure, conformation in aqueous solution, and intestinal ' 'immunomodulating activity of fucoidan from two brown seaweed species ' 'Sargassum crassifolium and Padina australis', 'volume': '147', 'author': 'Yuguchi', 'year': '2016', 'journal-title': 'Carbohydr. Polym.'}, { 'key': '10.1016/j.biteb.2020.100623_bb0550', 'doi-asserted-by': 'crossref', 'first-page': '1084', 'DOI': '10.3390/md13031084', 'article-title': 'Fucoidan from Macrocystis pyrifera has powerful immune-modulatory ' 'effects compared to three other fucoidans', 'volume': '13', 'author': 'Zhang', 'year': '2015', 'journal-title': 'Mar. Drugs'}, { 'issue': '8', 'key': '10.1016/j.biteb.2020.100623_bb0555', 'doi-asserted-by': 'crossref', 'first-page': '1261', 'DOI': '10.1080/07388551.2018.1472550', 'article-title': 'Insight into carrageenases: major review of sources, category, ' 'property, purification method, structure, and applications', 'volume': '38', 'author': 'Zhu', 'year': '2018', 'journal-title': 'Crit. Rev. Biotechnol.'}, { 'key': '10.1016/j.biteb.2020.100623_bb0560', 'doi-asserted-by': 'crossref', 'first-page': '727', 'DOI': '10.1056/NEJMoa2001017', 'article-title': 'A novel coronavirus from patients with pneumonia in China, 2019', 'volume': '382', 'author': 'Zhu', 'year': '2020', 'journal-title': 'N. Engl. J. 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