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Home   COVID-19 treatment studies for Vitamin D  COVID-19 treatment studies for Vitamin D  C19 studies: Vitamin D  Vitamin D   Select treatmentSelect treatmentTreatmentsTreatments
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All Studies   Meta Analysis   Recent: 
0 0.5 1 1.5 2+ Mortality 25% Improvement Relative Risk c19early.org/d Güven et al. Vitamin D for COVID-19 ICU PATIENTS Favors vitamin D Favors control
The effect of high-dose parenteral vitamin D3 on COVID-19-related inhospital mortality in critical COVID-19 patients during intensive care unit admission: an observational cohort study
Güven et al, European Journal of Clinical Nutrition, doi:10.1038/s41430-021-00984-5
23 Jul 2021    Source   PDF   Share   Tweet
Retrospective 175 ICU patients, 113 treated with a single dose of 300,000IU intramuscular cholecalciferol, showing lower mortality with treatment, but not reaching statistical significance. Calcifediol or calcitriol, which avoids several days delay in conversion, may be more successful, especially with this very late stage usage.
risk of death, 24.8% lower, RR 0.75, p = 0.32, treatment 43 of 113 (38.1%), control 30 of 62 (48.4%), NNT 9.7, odds ratio converted to relative risk.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
This study is excluded in the after exclusion results of meta analysis: very late stage, ICU patients.
Güven et al., 23 Jul 2021, retrospective, Turkey, peer-reviewed, 2 authors, dosage 300,000IU single dose.
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This PaperVitamin DAll
Late treatment
is less effective
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