Analgesics
Antiandrogens
Azvudine
Bromhexine
Budesonide
Colchicine
Conv. Plasma
Curcumin
Famotidine
Favipiravir
Fluvoxamine
Hydroxychlor..
Ivermectin
Lifestyle
Melatonin
Metformin
Minerals
Molnupiravir
Monoclonals
Naso/orophar..
Nigella Sativa
Nitazoxanide
Paxlovid
Quercetin
Remdesivir
Thermotherapy
Vitamins
More

Other
Feedback
Home
Top
Results
Abstract
All aspirin studies
Meta analysis
 
Feedback
Home
next
study
previous
study
c19early.org COVID-19 treatment researchAspirinAspirin (more..)
Melatonin Meta
Metformin Meta
Azvudine Meta
Bromhexine Meta Molnupiravir Meta
Budesonide Meta
Colchicine Meta
Conv. Plasma Meta Nigella Sativa Meta
Curcumin Meta Nitazoxanide Meta
Famotidine Meta Paxlovid Meta
Favipiravir Meta Quercetin Meta
Fluvoxamine Meta Remdesivir Meta
Hydroxychlor.. Meta Thermotherapy Meta
Ivermectin Meta

All Studies   Meta Analysis    Recent:   
0 0.5 1 1.5 2+ Death/hospitalization 59% primary Improvement Relative Risk Death/hospitalization (b) 71% Mortality 15% unadjusted Ventilation 9% unadjusted Hospitalization 48% unadjusted Progression 42% unadjusted Aspirin  de Jesús Ascencio-Montiel et al.  EARLY TREATMENT Is early treatment with aspirin + combined treatments beneficial for COVID-19? Retrospective 28,048 patients in Mexico Lower death/hosp. (p<0.0001) and hospitalization (p<0.0001) c19early.org de Jesús Ascencio-Montiel et al., Arch.., Jan 2022 Favors aspirin Favors control

A Multimodal Strategy to Reduce the Risk of Hospitalization/death in Ambulatory Patients with COVID-19

de Jesús Ascencio-Montiel et al., Archives of Medical Research, doi:10.1016/j.arcmed.2022.01.002
Jan 2022  
  Post
  Facebook
Share
  Source   PDF   All   Meta
Aspirin for COVID-19
24th treatment shown to reduce risk in August 2021
 
*, now known with p = 0.000087 from 73 studies, recognized in 2 countries.
Lower risk for mortality and progression.
No treatment is 100% effective. Protocols combine complementary and synergistic treatments. * >10% efficacy in meta analysis with ≥3 clinical studies.
4,000+ studies for 60+ treatments. c19early.org
Retrospective 28,048 COVID+ patients in Mexico, 7,898 receiving a treatment kit including low dose ivermectin, AZ, aspirin, and acetaminophen, shower lower mortality/hospitalization for those receiving the kit. Delivery of the treatment kit was based on availability in the medical units. Adherence is unknown and may be low. Adjusted results are only provided for combined mortality/hospitalization.
This study is excluded in meta analysis: combined treatments may contribute more to the effect seen.
Study covers aspirin and ivermectin.
risk of death/hospitalization, 59.0% lower, RR 0.41, p < 0.001, treatment 7,898, control 20,150, adjusted per study, multivariable, primary outcome.
risk of death/hospitalization, 71.0% lower, RR 0.29, p < 0.001, treatment 5,557, control 12,526, adjusted per study, with phone call followup, multivariable.
risk of death, 15.0% lower, RR 0.85, p = 0.16, treatment 101 of 7,898 (1.3%), control 303 of 20,150 (1.5%), NNT 445, unadjusted, excluded in exclusion analyses: unadjusted results with alternate outcome adjusted results showing significant changes with adjustments.
risk of mechanical ventilation, 9.1% lower, RR 0.91, p = 0.51, treatment 77 of 7,898 (1.0%), control 216 of 20,150 (1.1%), NNT 1031, unadjusted, excluded in exclusion analyses: unadjusted results with alternate outcome adjusted results showing significant changes with adjustments.
risk of hospitalization, 47.6% lower, RR 0.52, p < 0.001, treatment 485 of 7,898 (6.1%), control 2,360 of 20,150 (11.7%), NNT 18, unadjusted, excluded in exclusion analyses: unadjusted results with alternate outcome adjusted results showing significant changes with adjustments.
risk of progression, 41.8% lower, RR 0.58, p < 0.001, treatment 435 of 7,898 (5.5%), control 1,906 of 20,150 (9.5%), NNT 25, unadjusted, ER, excluded in exclusion analyses: unadjusted results with alternate outcome adjusted results showing significant changes with adjustments.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
de Jesús Ascencio-Montiel et al., 24 Jan 2022, retrospective, Mexico, peer-reviewed, 10 authors, this trial uses multiple treatments in the treatment arm (combined with AZ, acetaminophen, ivermectin) - results of individual treatments may vary.
This PaperAspirinAll
A Multimodal Strategy to Reduce the Risk of Hospitalization/death in Ambulatory Patients with COVID-19
Iván De Jesús Ascencio-Montiel, Juan Carlos Tomás-López, Verónica Álvarez-Medina, Luisa Estela Gil-Velázquez, Hortensia Vega-Vega, Héctor Raúl Vargas-Sánchez, Manuel Cervantes-Ocampo, Miguel Ángel Villasís-Keever, Cesar Raúl González-Bonilla, Célida Duque-Molina
Archives of Medical Research, doi:10.1016/j.arcmed.2022.01.002
This is a PDF file of an article that has undergone enhancements after acceptance, such as the addition of a cover page and metadata, and formatting for readability, but it is not yet the definitive version of record. This version will undergo additional copyediting, typesetting and review before it is published in its final form, but we are providing this version to give early visibility of the article. Please note that, during the production process, errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.
References
Abaleke, Abbas, Abbasi, Azithromycin in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, Arch Med Res
Bell, Norris-Grey, Luintel, Implementation and evaluation of a COVID-19 rapid follow-up service for patients discharged from the emergency department, Clin Med (Lond)
Bermúdez, Manso, Sánchez, Usefulness and acceptance of telephone monitoring by a virtual assistant for patients with COVID-19 following discharge, Rev Clin Esp (Barc)
Fagherazzi, Goetzinger, Rashid, Digital Health Strategies to Fight COVID-19 Worldwide: Challenges, Recommendations, and a Call for Papers, J Med Internet Res
Gootenberg, Kurtzman, Mara, Developing a pulse oximetry home monitoring protocol for patients suspected with COVID-19 after emergency department discharge, BMJ Health Care Inform
Hill, Garratt, Levi, Meta-analysis of Randomized Trials of Ivermectin to Treat SARS-CoV-2 Infection, Open Forum Infect Dis
Jaffery, Slakey, Zodda, Case Report: Disposition of Symptomatic Probable COVID-19, Clin Pract Cases Emerg Med
Lam, Sehgal, Andany, A virtual care program for outpatients diagnosed with COVID-19: A feasibility study, CMAJ Open
López, Lozano, Ruiz, Seguimiento telemático de COVID-19: Experiencia de un hospital terciario, An Pediatr (Barc)
Motta, Silva, Da, Borguezan, An emergency system for monitoring pulse oximetry, peak expiratory flow, and body temperature of patients with COVID-19 at home: Development and preliminary application, Arch Med Res
Vallejos, Zoni, Bangher, Ivermectin to prevent hospitalizations in patients with COVID-19 (IVERCOR-COVID19) a randomized, double-blind, placebo-controlled trial, BMC Infect Dis
Vindrola-Padros, Singh, Sidhu, Remote home monitoring (virtual wards) for confirmed or suspected COVID-19 patients: a rapid systematic review, E Clinical Medicine
Working, Epidemic Response, Cc, Dc, The epidemiological characteristics of an outbreak of 2019 novel coronavirus diseases (COVID-19) in China, Zhonghua Liu Xing Bing Xue Za Zhi
Wurzer, Spielhagen, Siegmann, Remote monitoring of COVID-19 positive high-risk patients in domestic isolation: A feasibility study, PLoS One
Loading..
Please send us corrections, updates, or comments. c19early involves the extraction of 100,000+ datapoints from thousands of papers. Community updates help ensure high accuracy. Treatments and other interventions are complementary. All practical, effective, and safe means should be used based on risk/benefit analysis. No treatment or intervention is 100% available and effective for all current and future variants. We do not provide medical advice. Before taking any medication, consult a qualified physician who can provide personalized advice and details of risks and benefits based on your medical history and situation. FLCCC and WCH provide treatment protocols.
  or use drag and drop   
Submit