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Fluoxetine use is associated with improved survival of patients with COVID-19 pneumonia: A retrospective case-control study

Németh et al., Ideggyógyászati Szeml, doi:10.18071/ISZ.74.0389 (date from preprint)
Aug 2021  
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Mortality 58% Improvement Relative Risk Fluvoxamine  Németh et al.  LATE TREATMENT Is late treatment with fluvoxamine beneficial for COVID-19? Retrospective 269 patients in Hungary Lower mortality with fluvoxamine (p=0.002) Németh et al., Ideggyógyászati Szeml, Aug 2021 Favorsfluvoxamine Favorscontrol 0 0.5 1 1.5 2+
27th treatment shown to reduce risk in November 2021
*, now with p = 0.00014 from 21 studies, recognized in 3 countries.
No treatment is 100% effective. Protocols combine treatments. * >10% efficacy, ≥3 studies.
4,400+ studies for 79 treatments.
Retrospective 269 hospitalized patients in Hungary, 110 treated with fluoxetine, showing lower mortality with treatment.
risk of death, 58.4% lower, RR 0.42, p = 0.002, treatment 15 of 110 (13.6%), control 49 of 159 (30.8%), NNT 5.8, adjusted per study, odds ratio converted to relative risk, multivariable logistic regression.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Németh et al., 12 Aug 2021, retrospective, Hungary, peer-reviewed, 6 authors.
This PaperFluvoxamineAll
Fluoxetine use is associated with improved survival of patients with COVID-19 pneumonia : A retrospective case-control study
Zsófia Klára Németh, Anna Szűcs, József Vitrai, Dóra Juhász, János Pál Németh, Dr András Holló
Ideggyógyászati szemle, doi:10.18071/isz.74.0389
Az alábbi dokumentumot magáncélra töltötték le az webportálról. A dokumentum felhasználása a szerzôi jog szabályozása alá esik. Kulcsszavak: fluoxetin, COVID-19, SARS-CoV-2, pneumonia, túlélés, mortalitás score did not show statistical difference between the fluoxetine and non-fluoxetine groups supporting the reliability of our finding. Conclusion -Provisional to confirmation in randomised controlled studies, fluoxetine may be a potent treatment increasing the survival for COVID-19 pneumonia.
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Late treatment
is less effective
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