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0 0.5 1 1.5 2+ Mortality 1% Improvement Relative Risk Vitamin D for COVID-19  Jalavu et al.  ICU PATIENTS Are vitamin D levels associated with COVID-19 outcomes? Prospective study of 86 patients in South Africa (Oct 2020 - Feb 2021) No significant difference in mortality Jalavu et al., IJID Regions, June 2023 Favors vitamin D Favors control

An investigation of the correlation of vitamin D status and management outcomes in patients with severe COVID-19 at a South African tertiary hospital

Jalavu et al., IJID Regions, doi:10.1016/j.ijregi.2023.05.007
Jun 2023  
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Vitamin D for COVID-19
8th treatment shown to reduce risk in October 2020
*, now known with p < 0.00000000001 from 120 studies, recognized in 8 countries.
No treatment is 100% effective. Protocols combine complementary and synergistic treatments. * >10% efficacy in meta analysis with ≥3 clinical studies.
4,100+ studies for 60+ treatments.
Prospective analysis of 68 COVID-19 ICU patients in South Africa, showing a high prevalence of vitamin D deficiency/insufficiency. There was no significant difference in mortality based on vitamin D sufficiency, however this result does not account for the different risk of being admitted to the ICU, or potential supplementation during the course of COVID-19 prior to ICU admission.
This is the 181st of 196 COVID-19 sufficiency studies for vitamin D, which collectively show higher levels reduce risk with p<0.0000000001 (1 in 11,637 vigintillion).
risk of death, 1.0% lower, HR 0.99, p = 0.97, high D levels (≥50nmol/L) 16 of 31 (51.6%), low D levels (<50nmol/L) 38 of 55 (69.1%), NNT 5.7, Kaplan–Meier.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Jalavu et al., 1 Jun 2023, prospective, South Africa, peer-reviewed, 16 authors, study period 29 October, 2020 - 10 February, 2021. Contact:
This PaperVitamin DAll
An investigation of the correlation of vitamin D status and management outcomes in patients with severe COVID-19 at a South African tertiary hospital
Thumeka P Jalavu, Lovemore N Sigwadhi, Maritha J Kotze, Anteneh Yalew, Vera Ngah, Jacques L Tamuzi, Zivanai C Chapanduka, Brian W Allwood, Coenraad F Koegelenberg, Elvis M Irusen, Usha Lalla, Tandi E Matsha, Rajiv T Erasmus, Ali Zumla, Annalise E Zemlin, Peter S Nyasulu
IJID Regions, doi:10.1016/j.ijregi.2023.05.007
investigation of the correlation of vitamin D status and management outcomes in patients with severe COVID-19 at a South African tertiary hospital, IJID Regions (2023),
Africa, Mid-year population estimates
Africa, Protection of Personal Information Act
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