Alkalinization
Analgesics..
Antiandrogens..
Bromhexine
Budesonide
Cannabidiol
Colchicine
Conv. Plasma
Curcumin
Ensovibep
Famotidine
Favipiravir
Fluvoxamine
Hydroxychlor..
Iota-carragee..
Ivermectin
Lactoferrin
Lifestyle..
Melatonin
Metformin
Molnupiravir
Monoclonals..
Nigella Sativa
Nitazoxanide
Nitric Oxide
Paxlovid
Peg.. Lambda
Povidone-Iod..
Quercetin
Remdesivir
Vitamins..
Zinc

Other
Feedback
Home
Home   COVID-19 treatment studies for Vitamin D  COVID-19 treatment studies for Vitamin D  C19 studies: Vitamin D  Vitamin D   Select treatmentSelect treatmentTreatmentsTreatments
Alkalinization Meta Lactoferrin Meta
Melatonin Meta
Bromhexine Meta Metformin Meta
Budesonide Meta Molnupiravir Meta
Cannabidiol Meta
Colchicine Meta Nigella Sativa Meta
Conv. Plasma Meta Nitazoxanide Meta
Curcumin Meta Nitric Oxide Meta
Ensovibep Meta Paxlovid Meta
Famotidine Meta Peg.. Lambda Meta
Favipiravir Meta Povidone-Iod.. Meta
Fluvoxamine Meta Quercetin Meta
Hydroxychlor.. Meta Remdesivir Meta
Iota-carragee.. Meta
Ivermectin Meta Zinc Meta

Other Treatments Global Adoption
All Studies   Meta Analysis   Recent:  
0 0.5 1 1.5 2+ Mortality 15% Improvement Relative Risk c19early.org/d Bogliolo et al. Vitamin D for COVID-19 Sufficiency Are vitamin D levels associated with COVID-19 outcomes? Prospective study of 361 patients in Italy (March - August 2020) Lower mortality with higher vitamin D levels (not stat. sig., p=0.29) Bogliolo et al., Frontiers in Nutrition, doi:10.3389/fnut.2022.934258 Favors vitamin D Favors control
Vitamin D 25OH Deficiency and Mortality in Moderate to Severe COVID-19: A Multi-Center Prospective Observational Study
Bogliolo et al., Frontiers in Nutrition, doi:10.3389/fnut.2022.934258
Bogliolo et al., Vitamin D 25OH Deficiency and Mortality in Moderate to Severe COVID-19: A Multi-Center Prospective.., Frontiers in Nutrition, doi:10.3389/fnut.2022.934258
Jul 2022   Source   PDF  
  Twitter
  Facebook
Share
  All Studies   Meta
Prospective 361 consecutive hospitalized patients in Italy, showing 77% had vitamin D deficiency. There was no statistically significant difference in mortality with deficiency.
risk of death, 15.3% lower, HR 0.85, p = 0.29, cutoff 20ng/mL, inverted to make HR<1 favor high D levels (≥20ng/mL).
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Bogliolo et al., 5 Jul 2022, prospective, Italy, peer-reviewed, median age 73.0, 16 authors, study period March 2020 - August 2020.
Contact: l.bogliolo@smatteo.pv.it.
All Studies   Meta Analysis   Submit Updates or Corrections
This PaperVitamin DAll
Abstract: BRIEF RESEARCH REPORT published: 05 July 2022 doi: 10.3389/fnut.2022.934258 Vitamin D 25OH Deficiency and Mortality in Moderate to Severe COVID-19: A Multi-Center Prospective Observational Study Laura Bogliolo 1*† , Emanuele Cereda 2† , Catherine Klersy 3 , Ludovico De Stefano 1 , Federica Lobascio 2 , Sara Masi 2 , Silvia Crotti 2 , Serena Bugatti 1 , Carlomaurizio Montecucco 1 , Stefania Demontis 4 , Annalisa Mascheroni 5 , Nadia Cerutti 6 , Alberto Malesci 7 , Salvatore Corrao 8,9 , Riccardo Caccialanza 2† and the NUTRI-COVID19 Collaborative Working Group 9 1 Edited by: Kuo-Cheng Lu, Fu Jen Catholic University Hospital, Taiwan Reviewed by: Guoxun Chen, The University of Tennessee, United States Nasser M. Al-Daghri, King Saud University, Saudi Arabia *Correspondence: Laura Bogliolo l.bogliolo@smatteo.pv.it † These authors have contributed equally to this work Specialty section: This article was submitted to Clinical Nutrition, a section of the journal Frontiers in Nutrition Received: 02 May 2022 Accepted: 15 June 2022 Published: 05 July 2022 Citation: Bogliolo L, Cereda E, Klersy C, Stefano LD, Lobascio F, Masi S, Crotti S, Bugatti S, Montecucco C, Demontis S, Mascheroni A, Cerutti N, Malesci A, Corrao S, Caccialanza R and the NUTRI-COVID19 Collaborative Working Group (2022) Vitamin D 25OH Deficiency and Mortality in Moderate to Severe COVID-19: A Multi-Center Prospective Observational Study. Front. Nutr. 9:934258. doi: 10.3389/fnut.2022.934258 Frontiers in Nutrition | www.frontiersin.org Division of Rheumatology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy, 2 Clinical Nutrition and Dietetics Unit, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy, 3 Clinical Epidemiology & Biostatistics Unit, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy, 4 Nutritional Unit, Giovanni Borea Civil Hospital, Sanremo, Italy, 5 Clinical Nutrition and Dietetics Unit–ASST Melegnano e Martesana, Melegnano (Milano), Italy, 6 Medicine and Dietetics Unit, ASST Pavia, Pavia, Italy, 7 Division of Gastroenterology and Digestive Endoscopy, Department of Gastroenterology, Humanitas Research Hospital, Milano, Italy, 8 Department of Health Promotion Sciences, Maternal and Infant Care, Internal Medicine and Medical Specialties (PROMISE), University of Palermo, Palermo, Italy, 9 COVID Unit, Department of Internal Medicine, National Relevance and High Specialization Hospital Trust ARNAS Civico, Di Cristina, Benfratelli, Palermo, Italy Introduction: Several studies and meta-analyses suggested the role of vitamin D 25OH in preventing severe forms of coronavirus disease 2019 (COVID-19). However, the evidence on the clinical benefits of vitamin D 25OH adequacy in patients hospitalized for COVID-19 remain conflicting and speculative. We aimed to investigate the association between vitamin D 25OH serum levels and mortality in hospitalized patients with moderate to severe COVID-19. Method: This prospective observational multicentre study included 361 consecutive patients with moderate to severe COVID-19 admitted to the Italian hospitals involved in the NUTRI-COVID19 trial from March to August 2020. For each patient, serum vitamin D 25OH levels were assessed 48 h since admission and classified as deficient (<20 ng/mL) or adequate (≥20 ng/mL). We built a propensity score for low/adequate vitamin D 25OH levels to balance the clinical and demographic properties of the cohort, which resulted in 261 patients with good common support used for the survival..
Loading..
Please send us corrections, updates, or comments. Vaccines and treatments are complementary. All practical, effective, and safe means should be used based on risk/benefit analysis. No treatment, vaccine, or intervention is 100% available and effective for all current and future variants. We do not provide medical advice. Before taking any medication, consult a qualified physician who can provide personalized advice and details of risks and benefits based on your medical history and situation. FLCCC and WCH provide treatment protocols.
  or use drag and drop   
Submit