Vitamin D Status and COVID-19 Clinical Outcomes in Hospitalized Patients
Betsy Szeto, Jason E Zucker, Elijah D Lasota, Mishaela R Rubin, Marcella D Walker, Michael T Yin, Adi Cohen
Endocrine Research, doi:10.1080/07435800.2020.1867162
Context: Populations severely affected by COVID-19 are also at risk for vitamin D deficiency. Common risk factors include older age, chronic illness, obesity, and non-Caucasian race. Vitamin D deficiency has been associated with risk for respiratory infections and failure, susceptibility and response to therapy for enveloped virus infection, and immune-mediated inflammatory reaction. Objective: To test the hypothesis that 25-hydroxyvitamin D[25(OH)D] deficiency is a risk factor for severity of COVID-19 respiratory and inflammatory complications. Design: We examined the relationship between prehospitalization 25(OH)D levels (obtained 1-365 days prior to admission) and COVID-19 clinical outcomes in 700 COVID-19 positive hospitalized patients.
Disclosure Statement The authors have nothing to disclose.
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