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Countercurrent chromatography isolation of green propolis biomarkers: potential blockers of SARS-CoV-2 RBD and ACE2 interaction

dos Santos et al., Journal of Chromatography A, doi:10.1016/j.chroma.2024.465265
Aug 2024  
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In Vitro study showing potential inhibition of SARS-CoV-2 spike protein and ACE2 interaction by artepillin C and baccharin from Brazilian green propolis. Artepillin C showed 67.3% inhibition of Spike:ACE2 interaction at 10 μM, while baccharin showed 51% inhibition.
3 preclinical studies support the efficacy of propolis for COVID-19:
dos Santos et al., 13 Aug 2024, peer-reviewed, 9 authors.
In Vitro studies are an important part of preclinical research, however results may be very different in vivo.
This PaperPropolisAll
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