Stand der Forschung zum In-vivo-Einsatz von hypochloriger Säure
Felix Herth, Dirk Boecker, Roland Breves, Axel Kramer, Dr. rer. nat Dirk Boecker
doi:10.3205/dgkh000433,URN:urn:nbn:de:0183-dgkh0004335
Antimicrobial efficacy, mode of action and in vivo use of hypochlorous acid (HOCl) for prevention or therapeutic support of infections In-vivo-Verwendung von hypochloriger Säure (HOCl) zur Prophylaxe oder Therapieunterstützung bei Infektionen. Eine Literaturübersicht
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doi:10.1056/NEJMc2001737DOI record:
{
"DOI": "10.3205/DGKH000433",
"URL": "https://journals.publisso.de/en/journals/hic/volume18/dgkh000433",
"abstract": "The objective is to provide a comprehensive overview of the rapidly developing field of the current state of research on in vivo use of hypochlorous acid (HOCl) to aid infection prevention and control, including naso-pharyngeal, alveolar, topical, and systemic HOCl applications. Also, examples are provided of dedicated applications in COVID-19. A brief background of HOCl’s biological and chemical specifics and its physiological role in the innate immune system is provided to understand the effect of in vivo applications in the context of the body’s own physiological defense mechanisms.",
"author": [
{
"family": "Boecker",
"given": "Dirk"
},
{
"family": "Zhang",
"given": "Zhentian"
},
{
"family": "Breves",
"given": "Roland"
},
{
"family": "Herth",
"given": "Felix"
},
{
"family": "Kramer",
"given": "Axel"
},
{
"family": "Bulitta",
"given": "Clemens"
}
],
"categories": [
"hypochlorous acid",
"in vivo application",
"HOCl chemistry",
"innate immune response",
"tissue compatibility",
"infection control",
"inhalation",
"wound care",
"disinfection",
"Hypochlorige Säure",
"In-vivo-Anwendung",
"HOCl-Chemie",
"physiologische Immunantwort",
"Gewebeverträglichkei",
"Infektionsprävention",
"Inhalation",
"Wundpflege",
"Desinfektion",
"Medicine and health"
],
"copyright": "Creative Commons Attribution 4.0 International",
"id": "https://doi.org/10.3205/dgkh000433",
"issued": {
"date-parts": [
[
2023,
3,
27
]
]
},
"language": "en",
"publisher": "German Medical Science GMS Publishing House",
"title": "Antimicrobial efficacy, mode of action and in vivo use of hypochlorous acid (HOCl) for prevention or therapeutic support of infections",
"type": "article-journal"
}
