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All Studies   Meta Analysis    Recent:   

Examine the association between severe vitamin D deficiency and mortality in patients with Covid-19

Anjum et al., Pakistan J. Med. Heal. Sci., 14:3
Jul 2020  
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0 0.5 1 1.5 2+ Mortality 62% Improvement Relative Risk Vitamin D for COVID-19  Anjum et al.  Sufficiency Are vitamin D levels associated with COVID-19 outcomes? Prospective study of 140 patients in Pakistan (Mar - Jun 2020) Lower mortality with higher vitamin D levels (p=0.02) c19early.org Anjum et al., Pakistan J. Med. Heal. S.., Jul 2020 Favors vitamin D Favors control
Vitamin D for COVID-19
8th treatment shown to reduce risk in October 2020
 
*, now known with p < 0.00000000001 from 120 studies, recognized in 9 countries.
No treatment is 100% effective. Protocols combine complementary and synergistic treatments. * >10% efficacy in meta analysis with ≥3 clinical studies.
4,200+ studies for 70+ treatments. c19early.org
Prospective study of 140 COVID-19 patients in Pakistan, showing significantly higher mortality with vitamin D deficiency.
This is the 8th of 198 COVID-19 sufficiency studies for vitamin D, which collectively show higher levels reduce risk with p<0.0000000001 (1 in 361,397 vigintillion).
This study is excluded in the after exclusion results of meta analysis: unadjusted results with no group details.
risk of death, 62.5% lower, RR 0.38, p = 0.02, high D levels (≥25nmol/L) 8 of 80 (10.0%), low D levels (<25nmol/L) 16 of 60 (26.7%), NNT 6.0.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Anjum et al., 31 Jul 2020, prospective, Pakistan, peer-reviewed, 6 authors, study period March 2020 - June 2020.
This PaperVitamin DAll
Examine the Association Between Severe Vitamin D Deficiency and Mortality in Patients with Covid-19
Dr Shakeel Anjum, Saima Suleman, Saadullah Afridi, Ghazala Yasmeen, Saleha Afridi, Yar Khan
Aim: To determine the association between severe vitamin D deficiency and mortality in patients presented with covid-19.
References
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Maghbooli, Sahraian, Ebrahimi, Pazoki, Kafan et al., Vitamin D sufficiency, a serum 25-hydroxyvitamin D at least 30 ng/mL reduced risk for adverse clinical outcomes in patients with COVID-19 infection, PLoS ONE, doi:10.1371/journal.pone.0239799
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Ortega, Serrano, Pujol, Rangel, Role of changes in SARS-CoV-2 spike protein in the interaction with the human ACE2 receptor: An in silico analysis, EXCLI journal
Owah, Fan, Dennett, Hagtvedt, Straube, Vitamin D levels and deficiency with different occupations: a systematic review, BMC Public Health
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Umhau, Casting sunlight on an epidemic: is vitamin D a critical host factor to prevent COVID-19? MedPage Today
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Xu, Yang, Chen, Luo, Zhang et al., Vitamin D alleviates lipopolysaccharideinduced acute lung injury via regulation of the reninangiotensin system, Molecular medicine reports
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