HomeCOVID-19 treatment studies for Vitamin D COVID-19 treatment studies for Vitamin D C19 studies: Vitamin D Vitamin D Select treatmentSelect treatmentTreatmentsTreatments
Prospective study of 140 COVID-19 patients in Pakistan, showing significantly higher mortality with vitamin D deficiency.
This study is excluded in the after exclusion results of meta
analysis:
unadjusted results with no group details.
Abstract: ORIGINAL ARTICLE
Examine the Association Between Severe Vitamin D Deficiency and
Mortality in Patients with Covid-19
SHAKEEL ANJUM1, SAIMA SULEMAN2, SAADULLAH AFRIDI3, GHAZALA YASMEEN4, MOHAMMAD IKRAM SHAH5,
SALEHA AFRIDI6
1
Assistant Professor in Rheumatology Niazi Medical College, Sargodha
Senior House Officer, Internal Medicine department Shaikh Zayed Hospital, Lahore
3
Director Sarhad Institute of Health Sciences, Sarhad University, Peshawar
4
Demonstrator Community Medicine, Sheikh Zayed Medical College, Rahim Yar Khan
5
Assistant professor (Medicine) Jinnah Medical College Peshawar
6
Associate Professor Sarhad Institute of Health Sciences, Sarhad University Peshawar
Correspondence to: Dr. Shakeel Anjum, Email: docshakeelanjum@gmail.com. Mobile No: +923316662103
2
ABSTRACT
Aim: To determine the association between severe vitamin D deficiency and mortality in patients presented with
covid-19.
Study Design: Prospective/Observational
Place and Duration: Shaikh Zayed Hospital, Rahim Yar Khan during from March 2020 to June 2020.
Materials & Methods: Total 140 patients of both genders diagnosed to have covid-19 were enrolled in this study.
Patients ages were ranging from 15 years to 75 years. Detailed demographics including age, sex, and body mass
index (BMI) were recorded after taking written consent. 5 ml blood sample was taken from all the patients to
examine the vitamin D level. Severe Vitamin D deficiency was defined as 25(OH)D < 25 nmol/L (10 ng/dL).
Association between mortality and severe vitamin D deficiency was examined. Data was analyzed by SPSS 24.0.
Results: Out of 140 patients, 82 (58.57%) were males while 58 (41.43%) were females with mean age
42.46±14.73 years. Severe vitamin D deficiency was observed in 60 (42.86%) patients. Mortality found in 22
(15.71%) patients. Patients with severe vitamin D deficiency had high rate of mortality 16 (26.67%) as compared
to patients with no vitamin D deficiency 6 (7.5%), a significant association was observed between severe vitamin
D deficiency and mortality in patients with covid-19 disease with p-value <0.05.
Conclusion: It is concluded that there was strong relationship between severe vitamin-D deficiency and mortality
in patients with covid-19 disease.
Keywords: Covid-19, Vitamin D Deficiency, Mortality
Please send us corrections, updates, or comments. Vaccines and
treatments are complementary. All practical, effective, and safe means should
be used based on risk/benefit analysis. No treatment, vaccine, or intervention
is 100% available and effective for all current and future variants. We do not
provide medical advice. Before taking any medication, consult a qualified
physician who can provide personalized advice and details of risks and
benefits based on your medical history and situation. FLCCC and WCH
provide treatment protocols.