Diabetes and SARS-CoV-2 Infection: The Potential Role of Antidiabetic Therapy in the Evolution of COVID-19
Biagio Pinchera, Nicola Schiano Moriello, Antonio Riccardo Buonomo, Isabella Di Filippo, Anastasia Tanzillo, Giorgio Buzzo, Riccardo Villari, Ivan Gentile
Microorganisms, doi:10.3390/microorganisms11010145
Diabetes mellitus represents one of the most frequent comorbidities among patients with COVID-19, constituting a risk factor for a more severe prognosis than that of non-diabetic patients. However, the pathophysiological mechanism underlying this unfavorable outcome is still not completely clear. The goal of our study was to evaluate the potential role of antidiabetic therapy in the evolution of COVID-19.
Author Contributions: B.P. participated in substantial contributions to the conception and design of the work and the acquisition, analysis and interpretation data for the work. N.S.M. conceived idea with analysis and participated in interpreting the literature, drafting the article, approving the final version to be published, and being accountable for the accuracy/integrity of the content. A.R.B. participated in revising the initial draft of the article and approving the final version to be published. I.D.F. participated in drafting the article and approving the final version to be published. A.T. participated in analysis and interpretation of data for the work. G.B. participated in the acquisition and analysis of data for the work. R.V. conceived idea with analysis and participated in interpreting the literature, approving the final version to be published, and being accountable for the accuracy/integrity of the content. I.G. participated in substantial contributions to the conception and design of the work; the acquisition, analysis and interpretation of data for the work; approval for the final version to be published. All authors have read and agreed to the published version of the manuscript.
Conflicts of Interest: The authors declare no conflict of interest.
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