The effect of curcumin on the risk of mortality in patients with COVID-19: A systematic review and meta-analysis of randomized trials
et al., Phytotherapy Research, doi:10.1002/ptr.7468
, The effect of curcumin on the risk of mortality in patients with COVID-19: A systematic review and.., Phytotherapy Research, doi:10.1002/ptr.7468
Meta analysis of 3 curcumin RCTs showing lower mortality with treatment. Author notes the small sample sizes of the included trials.Currently there are 24 curcumin studies and meta analysis shows:
| Outcome | Improvement |
|---|---|
| Mortality | 63% lower [35‑79%] |
| Ventilation | 77% lower [-6‑95%] |
| ICU admission | 67% lower [-211‑96%] |
| Hospitalization | 25% lower [15‑33%] |
|
risk of death, 77.0% lower, OR 0.23, p = 0.002, RR approximated with OR.
|
| Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates |
Kow et al., 28 Apr 2022, peer-reviewed, 3 authors.
Contact:
chiasiang_93@hotmail.com.
The effect of curcumin on the risk of mortality in patients with COVID ‐19: A systematic review and meta‐analysis of randomized trials
Phytotherapy Research, doi:10.1002/ptr.7468
The coronavirus disease 2019 (COVID-19) pandemic is far from bygone, with the emergence of newer variations of concern of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). While the worldwide vaccine rollout has progressed at a breakneck pace, the hunt for new safe, effective, and targeted treatments should continue in parallel due to the frequent occurrence of breakthrough cases. Curcumin is one such natural polyphenolic compound with multiple benefits, including antiviral, anti-inflammatory, anticoagulant, antiplatelet,
CONFLICT OF INTEREST The authors declare no conflict of interest.
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