The effectiveness of nano‐curcumin on patients with COVID‐19: A systematic review of clinical trials

{ 'indexed': {'date-parts': [[2023, 2, 18]], 'date-time': '2023-02-18T05:37:10Z', 'timestamp': 1676698630865}, 'reference-count': 90, 'publisher': 'Wiley', 'license': [ { 'start': { 'date-parts': [[2023, 2, 17]], 'date-time': '2023-02-17T00:00:00Z', 'timestamp': 1676592000000}, 'content-version': 'vor', 'delay-in-days': 0, 'URL': 'http://onlinelibrary.wiley.com/termsAndConditions#vor'}, { 'start': { 'date-parts': [[2023, 2, 17]], 'date-time': '2023-02-17T00:00:00Z', 'timestamp': 1676592000000}, 'content-version': 'tdm', 'delay-in-days': 0, 'URL': 'http://doi.wiley.com/10.1002/tdm_license_1.1'}], 'funder': [ { 'DOI': '10.13039/501100006769', 'name': 'Russian Science Foundation', 'doi-asserted-by': 'publisher', 'award': ['22‐15‐00064']}], 'content-domain': {'domain': ['onlinelibrary.wiley.com'], 'crossmark-restriction': True}, 'DOI': '10.1002/ptr.7778', 'type': 'journal-article', 'created': {'date-parts': [[2023, 2, 17]], 'date-time': '2023-02-17T12:14:28Z', 'timestamp': 1676636068000}, 'update-policy': 'http://dx.doi.org/10.1002/crossmark_policy', 'source': 'Crossref', 'is-referenced-by-count': 0, 'title': 'The effectiveness of nano‐curcumin on patients with\n' ' <scp>COVID</scp>\n' ' ‐19: A systematic review of clinical trials', 'prefix': '10.1002', 'author': [ { 'given': 'Mehrnaz', 'family': 'Shojaei', 'sequence': 'first', 'affiliation': [ { 'name': 'Student Research Committee, Department of Community Nutrition ' 'School of Nutrition and Food Science Isfahan University of ' 'Medical Sciences Isfahan Iran'}]}, { 'given': 'Sahar', 'family': 'Foshati', 'sequence': 'additional', 'affiliation': [ { 'name': 'Food Security Research Center, Department of Clinical Nutrition ' 'School of Nutrition and Food Science Isfahan University of ' 'Medical Sciences Isfahan Iran'}]}, { 'given': 'Mohaddese', 'family': 'Abdi', 'sequence': 'additional', 'affiliation': [ { 'name': 'Student Research Committee, Department of Community Nutrition ' 'School of Nutrition and Food Science Isfahan University of ' 'Medical Sciences Isfahan Iran'}]}, { 'given': 'Gholamreza', 'family': 'Askari', 'sequence': 'additional', 'affiliation': [ { 'name': 'Food Security Research Center and Department of Community ' 'Nutrition, School of Nutrition and Food Science Isfahan ' 'University of Medical Sciences Isfahan Iran'}, { 'name': 'Anesthesia and Critical Care Research Center Isfahan University ' 'of Medical Sciences Isfahan Iran'}]}, { 'given': 'Vasily N.', 'family': 'Sukhorukov', 'sequence': 'additional', 'affiliation': [{'name': 'Institute for Atherosclerosis Research Moscow Russia'}]}, { 'given': 'Mohammad', 'family': 'Bagherniya', 'sequence': 'additional', 'affiliation': [ { 'name': 'Food Security Research Center and Department of Community ' 'Nutrition, School of Nutrition and Food Science Isfahan ' 'University of Medical Sciences Isfahan Iran'}, { 'name': 'Anesthesia and Critical Care Research Center Isfahan University ' 'of Medical Sciences Isfahan Iran'}]}, { 'ORCID': 'http://orcid.org/0000-0002-8656-1444', 'authenticated-orcid': False, 'given': 'Amirhossein', 'family': 'Sahebkar', 'sequence': 'additional', 'affiliation': [ { 'name': 'Applied Biomedical Research Center Mashhad University of Medical ' 'Sciences Mashhad Iran'}, { 'name': 'Biotechnology Research Center Pharmaceutical Technology ' 'Institute, Mashhad University of Medical Sciences Mashhad Iran'}, { 'name': 'School of Medicine The University of Western Australia Perth ' 'Australia'}, { 'name': 'Department of Biotechnology, School of Pharmacy Mashhad ' 'University of Medical Sciences Mashhad Iran'}]}], 'member': '311', 'published-online': {'date-parts': [[2023, 2, 17]]}, 'reference': [ { 'issue': '1', 'key': 'e_1_2_9_2_1', 'doi-asserted-by': 'crossref', 'first-page': '14', 'DOI': '10.5582/ddt.2022.01017', 'article-title': 'The effects of curcumin as dietary supplement for patients with ' 'COVID‐19: A systematic review of randomized clinical trials', 'volume': '16', 'author': 'Abdelazeem B.', 'year': '2022', 'journal-title': 'Drug Discoveries & Therapeutics'}, {'key': 'e_1_2_9_3_1', 'doi-asserted-by': 'publisher', 'DOI': '10.1002/fsn3.2226'}, {'key': 'e_1_2_9_4_1', 'doi-asserted-by': 'publisher', 'DOI': '10.1016/j.tifs.2020.03.026'}, {'key': 'e_1_2_9_5_1', 'doi-asserted-by': 'publisher', 'DOI': '10.1002/biof.1694'}, {'key': 'e_1_2_9_6_1', 'doi-asserted-by': 'publisher', 'DOI': '10.1002/ptr.6939'}, {'key': 'e_1_2_9_7_1', 'doi-asserted-by': 'publisher', 'DOI': '10.3390/molecules25030724'}, {'key': 'e_1_2_9_8_1', 'doi-asserted-by': 'publisher', 'DOI': '10.1016/j.hjc.2020.05.007'}, {'key': 'e_1_2_9_9_1', 'doi-asserted-by': 'publisher', 'DOI': '10.1002/ptr.6571'}, { 'key': 'e_1_2_9_10_1', 'doi-asserted-by': 'crossref', 'first-page': '1023', 'DOI': '10.1002/ptr.7375', 'article-title': 'Antiinflammatory potential of nano‐curcumin as an alternative ' 'therapeutic agent for the treatment of mild‐to‐moderate hospitalized ' 'COVID‐19 patients in a placebo‐controlled clinical trial', 'volume': '36', 'author': 'Asadirad A.', 'year': '2022', 'journal-title': 'Phytotherapy Research'}, {'key': 'e_1_2_9_11_1', 'doi-asserted-by': 'publisher', 'DOI': '10.1002/fsn3.1858'}, {'key': 'e_1_2_9_12_1', 'doi-asserted-by': 'publisher', 'DOI': '10.1007/s10787-021-00902-y'}, {'key': 'e_1_2_9_13_1', 'doi-asserted-by': 'publisher', 'DOI': '10.1002/ptr.6776'}, {'key': 'e_1_2_9_14_1', 'doi-asserted-by': 'publisher', 'DOI': '10.1007/s12035-018-1169-7'}, { 'issue': '4', 'key': 'e_1_2_9_15_1', 'doi-asserted-by': 'crossref', 'first-page': '211', 'DOI': '10.15171/jhp.2018.33', 'article-title': 'Immunomodulatory, anti‐inflammatory, and antioxidant effects of ' 'curcumin', 'volume': '7', 'author': 'Boroumand N.', 'year': '2018', 'journal-title': 'Journal of Herbmed Pharmacology'}, {'key': 'e_1_2_9_16_1', 'doi-asserted-by': 'publisher', 'DOI': '10.1177/0968051907078605'}, { 'issue': '5', 'key': 'e_1_2_9_17_1', 'doi-asserted-by': 'crossref', 'first-page': '1093', 'DOI': '10.1007/s12250-021-00425-4', 'article-title': 'Consecutive monitoring of interleukin‐6 is needed for COVID‐19 patients', 'volume': '36', 'author': 'Chen X.', 'year': '2021', 'journal-title': 'Virologica Sinica'}, { 'issue': '16', 'key': 'e_1_2_9_18_1', 'doi-asserted-by': 'crossref', 'first-page': '2000460', 'DOI': '10.2807/1560-7917.ES.2020.25.16.2000460', 'article-title': 'Clinical characteristics of coronavirus disease (COVID‐19) early ' 'findings from a teaching hospital in Pavia, North Italy, 21 to February ' '28, 2020', 'volume': '25', 'author': 'Colaneri M.', 'year': '2020', 'journal-title': 'Eurosurveillance'}, { 'issue': '2', 'key': 'e_1_2_9_19_1', 'first-page': '327', 'article-title': 'Induction of pro‐inflammatory cytokines (IL‐1 and IL‐6) and lung ' 'inflammation by Coronavirus‐19 (COVI‐19 or SARS‐CoV‐2): ' 'Anti‐inflammatory strategies', 'volume': '34', 'author': 'Conti P.', 'year': '2020', 'journal-title': 'Journal of Biological Regulators and Homeostatic Agents'}, { 'key': 'e_1_2_9_20_1', 'doi-asserted-by': 'crossref', 'first-page': '104503', 'DOI': '10.1016/j.jff.2021.104503', 'article-title': 'Promising role of curcumin against viral diseases emphasizing COVID‐19 ' 'management: A review on the mechanistic insights with reference to ' 'host‐pathogen interaction and immunomodulation', 'volume': '82', 'author': 'Dhar S.', 'year': '2021', 'journal-title': 'Journal of Functional Foods'}, { 'key': 'e_1_2_9_21_1', 'doi-asserted-by': 'crossref', 'first-page': '101256', 'DOI': '10.1016/j.ctcp.2020.101256', 'article-title': 'The effects of nano‐curcumin supplementation on Th1/Th17 balance in ' 'migraine patients: A randomized controlled clinical trial', 'volume': '41', 'author': 'Djalali M.', 'year': '2020', 'journal-title': 'Complementary Therapies in Clinical Practice'}, { 'key': 'e_1_2_9_22_1', 'doi-asserted-by': 'crossref', 'first-page': '74', 'DOI': '10.1016/j.intimp.2018.05.018', 'article-title': 'Changes in Th17 cells function after nanocurcumin use to treat multiple ' 'sclerosis', 'volume': '61', 'author': 'Dolati S.', 'year': '2018', 'journal-title': 'International Immunopharmacology'}, { 'key': 'e_1_2_9_23_1', 'doi-asserted-by': 'crossref', 'first-page': '111578', 'DOI': '10.1016/j.biopha.2021.111578', 'article-title': 'Will curcumin nanosystems be the next promising antiviral alternatives ' 'in COVID‐19 treatment trials?', 'volume': '139', 'author': 'Dourado D.', 'year': '2021', 'journal-title': 'Biomedicine & Pharmacotherapy'}, {'key': 'e_1_2_9_24_1', 'doi-asserted-by': 'publisher', 'DOI': '10.1136/pgmj.2011.118398'}, { 'issue': '4', 'key': 'e_1_2_9_25_1', 'doi-asserted-by': 'crossref', 'first-page': '460', 'DOI': '10.1111/jcpt.12703', 'article-title': 'Curcumin in turmeric: Basic and clinical evidence for a potential role ' 'in analgesia', 'volume': '43', 'author': 'Eke‐Okoro U.', 'year': '2018', 'journal-title': 'Journal of Clinical Pharmacy and Therapeutics'}, { 'issue': '4', 'key': 'e_1_2_9_26_1', 'doi-asserted-by': 'crossref', 'first-page': '331', 'DOI': '10.1615/CritRevTherDrugCarrierSyst.2013007236', 'article-title': 'Nanocurcumin: A promising therapeutic advancement over native curcumin', 'volume': '30', 'author': 'Flora G.', 'year': '2013', 'journal-title': 'Critical Reviews™ in Therapeutic Drug Carrier Systems'}, { 'issue': '7', 'key': 'e_1_2_9_27_1', 'doi-asserted-by': 'crossref', 'first-page': 'e14254', 'DOI': '10.1111/ijcp.14254', 'article-title': 'The effect of extra virgin olive oil on anthropometric indices, lipid ' 'profile, and markers of oxidative stress and inflammation in patients ' 'with depression, a double‐blind randomised controlled trial', 'volume': '75', 'author': 'Foshati S.', 'year': '2021', 'journal-title': 'International Journal of Clinical Practice'}, {'key': 'e_1_2_9_28_1', 'doi-asserted-by': 'publisher', 'DOI': '10.1002/fsn3.3034'}, { 'key': 'e_1_2_9_29_1', 'doi-asserted-by': 'crossref', 'first-page': '111888', 'DOI': '10.1016/j.biopha.2021.111888', 'article-title': 'Pharmacological properties and underlying mechanisms of curcumin and ' 'prospects in medicinal potential', 'volume': '141', 'author': 'Fu Y.‐S.', 'year': '2021', 'journal-title': 'Biomedicine & Pharmacotherapy'}, {'key': 'e_1_2_9_30_1', 'doi-asserted-by': 'publisher', 'DOI': '10.1016/j.phrs.2017.02.008'}, { 'key': 'e_1_2_9_31_1', 'first-page': 'CD008424', 'article-title': 'Curcumin for maintenance of remission in ulcerative colitis', 'volume': '10', 'author': 'Garg S. K.', 'year': '2012', 'journal-title': 'Cochrane Database of Systematic Reviews'}, {'key': 'e_1_2_9_32_1', 'doi-asserted-by': 'publisher', 'DOI': '10.3390/jcm8122051'}, { 'issue': '11', 'key': 'e_1_2_9_33_1', 'doi-asserted-by': 'crossref', 'first-page': '6417', 'DOI': '10.1002/ptr.7294', 'article-title': 'A triple‐blind, placebo‐controlled, randomized clinical trial to ' 'evaluate the effect of curcumin‐containing nanomicelles on cellular ' 'immune responses subtypes and clinical outcome in COVID‐19 patients', 'volume': '35', 'author': 'Hassaniazad M.', 'year': '2021', 'journal-title': 'Phytotherapy Research'}, {'key': 'e_1_2_9_34_1', 'doi-asserted-by': 'publisher', 'DOI': '10.1002/biof.1932'}, {'key': 'e_1_2_9_35_1', 'doi-asserted-by': 'publisher', 'DOI': '10.1016/j.phrs.2020.104921'}, { 'issue': '3', 'key': 'e_1_2_9_36_1', 'first-page': '282', 'article-title': 'Novel nanomicelle formulation to enhance bioavailability and stability ' 'of curcuminoids', 'volume': '22', 'author': 'Hatamipour M.', 'year': '2019', 'journal-title': 'Iranian Journal of Basic Medical Sciences'}, {'key': 'e_1_2_9_37_1', 'doi-asserted-by': 'publisher', 'DOI': '10.1002/ptr.7350'}, { 'key': 'e_1_2_9_38_1', 'doi-asserted-by': 'crossref', 'unstructured': 'Higgins J. P.(2008).Cochrane handbook for systematic reviews of ' 'interventions version 5.0. 1. The Cochrane ' 'Collaboration.http://www.cochrane-handbook.org', 'DOI': '10.1002/9780470712184'}, { 'key': 'e_1_2_9_39_1', 'doi-asserted-by': 'crossref', 'first-page': '1013', 'DOI': '10.1002/ptr.7374', 'article-title': 'Effect of nanocurcumin supplementation on the severity of symptoms and ' 'length of hospital stay in patients with COVID‐19: A randomized ' 'double‐blind placebo‐controlled trial', 'volume': '36', 'author': 'Honarkar Shafie E.', 'year': '2022', 'journal-title': 'Phytotherapy Research'}, {'key': 'e_1_2_9_40_1', 'doi-asserted-by': 'publisher', 'DOI': '10.1002/biof.1713'}, { 'key': 'e_1_2_9_41_1', 'doi-asserted-by': 'publisher', 'DOI': '10.1016/j.phymed.2009.05.020'}, { 'issue': '5', 'key': 'e_1_2_9_42_1', 'doi-asserted-by': 'crossref', 'first-page': '691', 'DOI': '10.1002/ptr.5591', 'article-title': 'A critical approach to evaluating clinical efficacy, adverse events and ' 'drug interactions of herbal remedies', 'volume': '30', 'author': 'Izzo A. A.', 'year': '2016', 'journal-title': 'Phytotherapy Research'}, { 'issue': '10228', 'key': 'e_1_2_9_43_1', 'doi-asserted-by': 'crossref', 'first-page': '949', 'DOI': '10.1016/S0140-6736(20)30419-0', 'article-title': 'A distinct name is needed for the new coronavirus', 'volume': '395', 'author': 'Jiang S.', 'year': '2020', 'journal-title': 'The Lancet'}, { 'key': 'e_1_2_9_44_1', 'doi-asserted-by': 'crossref', 'first-page': '207', 'DOI': '10.1016/j.compbiolchem.2017.11.001', 'article-title': 'Antiviral potential of natural compounds against influenza virus ' 'hemagglutinin', 'volume': '71', 'author': 'Kannan S.', 'year': '2017', 'journal-title': 'Computational Biology and Chemistry'}, { 'key': 'e_1_2_9_45_1', 'doi-asserted-by': 'crossref', 'first-page': '101122', 'DOI': '10.1016/j.eujim.2020.101122', 'article-title': 'Effects of nanocurcumin on inflammatory factors and clinical outcomes ' 'in critically ill patients with sepsis: A pilot randomized clinical ' 'trial', 'volume': '36', 'author': 'Karimi A.', 'year': '2020', 'journal-title': 'European Journal of Integrative Medicine'}, { 'key': 'e_1_2_9_46_1', 'doi-asserted-by': 'crossref', 'first-page': '6596', 'DOI': '10.1039/D1FO03746C', 'article-title': 'Nano‐curcumin supplementation in critically ill patients with sepsis: A ' 'randomized clinical trial investigating the inflammatory biomarkers, ' 'oxidative stress indices, endothelial function, clinical outcomes and ' 'nutritional status', 'volume': '13', 'author': 'Karimi A.', 'year': '2022', 'journal-title': 'Food & Function'}, { 'key': 'e_1_2_9_47_1', 'doi-asserted-by': 'crossref', 'first-page': '487', 'DOI': '10.3389/fphar.2020.00487', 'article-title': 'Nanocurcumin: A promising candidate for therapeutic applications', 'volume': '11', 'author': 'Karthikeyan A.', 'year': '2020', 'journal-title': 'Frontiers in Pharmacology'}, { 'issue': '8', 'key': 'e_1_2_9_48_1', 'doi-asserted-by': 'crossref', 'first-page': '1004', 'DOI': '10.1016/j.jsps.2020.06.022', 'article-title': 'COVID‐19: Clinical aspects and therapeutics responses', 'volume': '28', 'author': 'Khan S.', 'year': '2020', 'journal-title': 'Saudi Pharmaceutical Journal'}, { 'key': 'e_1_2_9_49_1', 'doi-asserted-by': 'publisher', 'DOI': '10.1016/j.biopha.2022.113621'}, { 'key': 'e_1_2_9_50_1', 'doi-asserted-by': 'crossref', 'unstructured': 'Kow C. S. Ramachandram D. S. &Hasan S. S.(2022).The effect of curcumin ' 'on the risk of mortality in patients with COVID‐19: A systematic review ' 'and meta‐analysis of randomized trials. Phytotherapy Research.', 'DOI': '10.1002/ptr.7468'}, { 'issue': '9', 'key': 'e_1_2_9_51_1', 'doi-asserted-by': 'crossref', 'first-page': '705', 'DOI': '10.1080/17425255.2019.1650914', 'article-title': 'Is curcumin bioavailability a problem in humans: Lessons from clinical ' 'trials', 'volume': '15', 'author': 'Kunnumakkara A. B.', 'year': '2019', 'journal-title': 'Expert Opinion on Drug Metabolism & Toxicology'}, {'key': 'e_1_2_9_52_1', 'doi-asserted-by': 'publisher', 'DOI': '10.1016/j.ahj.2020.04.025'}, { 'key': 'e_1_2_9_53_1', 'doi-asserted-by': 'crossref', 'first-page': '133', 'DOI': '10.1016/j.phrs.2016.11.017', 'article-title': 'Curcumin use in pulmonary diseases: State of the art and future ' 'perspectives', 'volume': '115', 'author': 'Lelli D.', 'year': '2017', 'journal-title': 'Pharmacological Research'}, {'key': 'e_1_2_9_54_1', 'doi-asserted-by': 'publisher', 'DOI': '10.2174/1568011024606370'}, { 'issue': '4', 'key': 'e_1_2_9_55_1', 'doi-asserted-by': 'crossref', 'first-page': '424', 'DOI': '10.1002/jmv.25685', 'article-title': 'Coronavirus infections and immune responses', 'volume': '92', 'author': 'Li G.', 'year': '2020', 'journal-title': 'Journal of Medical Virology'}, {'key': 'e_1_2_9_56_1', 'doi-asserted-by': 'publisher', 'DOI': '10.1016/j.cyto.2020.155151'}, { 'key': 'e_1_2_9_57_1', 'doi-asserted-by': 'publisher', 'DOI': '10.1183/13993003.00607-2020'}, {'key': 'e_1_2_9_58_1', 'doi-asserted-by': 'publisher', 'DOI': '10.5114/aoms.2020.93739'}, {'key': 'e_1_2_9_59_1', 'doi-asserted-by': 'publisher', 'DOI': '10.1002/ptr.7273'}, { 'key': 'e_1_2_9_60_1', 'doi-asserted-by': 'publisher', 'DOI': '10.1016/j.autrev.2017.11.016'}, { 'issue': '5', 'key': 'e_1_2_9_61_1', 'doi-asserted-by': 'crossref', 'first-page': 'e13304', 'DOI': '10.1111/aji.13304', 'article-title': 'COVID‐19 and Treg/Th17 imbalance: Potential relationship to pregnancy ' 'outcomes', 'volume': '84', 'author': 'Muyayalo K. P.', 'year': '2020', 'journal-title': 'American Journal of Reproductive Immunology'}, { 'issue': '5', 'key': 'e_1_2_9_62_1', 'doi-asserted-by': 'crossref', 'first-page': 'e14093', 'DOI': '10.1111/jfbc.14093', 'article-title': 'Does nano‐curcumin supplementation improve hematological indices in ' 'critically ill patients with sepsis? A randomized controlled clinical ' 'trial', 'volume': '46', 'author': 'Naeini F.', 'year': '2022', 'journal-title': 'Journal of Food Biochemistry'}, { 'key': 'e_1_2_9_63_1', 'doi-asserted-by': 'crossref', 'first-page': 'n160', 'DOI': '10.1136/bmj.n160', 'article-title': 'PRISMA 2020 explanation and elaboration: Updated guidance and exemplars ' 'for reporting systematic reviews', 'volume': '372', 'author': 'Page M. J.', 'year': '2021', 'journal-title': 'BMJ'}, {'key': 'e_1_2_9_64_1', 'doi-asserted-by': 'publisher', 'DOI': '10.1055/s-0034-1389986'}, {'key': 'e_1_2_9_65_1', 'doi-asserted-by': 'publisher', 'DOI': '10.1016/j.ctim.2017.05.006'}, {'key': 'e_1_2_9_66_1', 'doi-asserted-by': 'publisher', 'DOI': '10.1016/j.phrs.2018.09.012'}, { 'issue': '2', 'key': 'e_1_2_9_67_1', 'first-page': '824', 'article-title': 'Curcumin as adjuvant therapy in COVID‐19: Friend or foe?', 'volume': '13', 'author': 'Pawitan J. A.', 'year': '2020', 'journal-title': 'Journal of International Dental and Medical Research'}, { 'key': 'e_1_2_9_68_1', 'doi-asserted-by': 'publisher', 'DOI': '10.1007/978-3-030-56153-6_10'}, { 'issue': '5', 'key': 'e_1_2_9_69_1', 'first-page': '567', 'article-title': 'The effect of nano‐curcumin on HbA1c, fasting blood glucose, and lipid ' 'profile in diabetic subjects: A randomized clinical trial', 'volume': '6', 'author': 'Rahimi H. R.', 'year': '2016', 'journal-title': 'Avicenna Journal of Phytomedicine'}, { 'key': 'e_1_2_9_70_1', 'doi-asserted-by': 'crossref', 'first-page': '675287', 'DOI': '10.3389/fphar.2021.675287', 'article-title': 'Curcumin as a potential treatment for COVID‐19', 'volume': '1068', 'author': 'Rattis B. A.', 'year': '2021', 'journal-title': 'Frontiers in Pharmacology'}, {'key': 'e_1_2_9_71_1', 'doi-asserted-by': 'publisher', 'DOI': '10.3389/fphar.2021.675287'}, {'key': 'e_1_2_9_72_1', 'doi-asserted-by': 'publisher', 'DOI': '10.18103/mra.v8i10.2248'}, { 'issue': '5', 'key': 'e_1_2_9_73_1', 'doi-asserted-by': 'crossref', 'first-page': '2616', 'DOI': '10.1002/ptr.7004', 'article-title': 'Oral nano‐curcumin formulation efficacy in management of mild to ' 'moderate hospitalized coronavirus disease‐19 patients: An open label ' 'nonrandomized clinical trial', 'volume': '35', 'author': 'Saber‐Moghaddam N.', 'year': '2021', 'journal-title': 'Phytotherapy Research'}, { 'key': 'e_1_2_9_74_1', 'doi-asserted-by': 'publisher', 'DOI': '10.1080/1061186X.2022.2141755'}, { 'issue': '1', 'key': 'e_1_2_9_75_1', 'doi-asserted-by': 'crossref', 'first-page': '1', 'DOI': '10.1186/s13104-022-06074-4', 'article-title': 'The effects of nano‐curcumin supplementation on adipokines levels in ' 'obese and overweight patients with migraine: A double blind clinical ' 'trial study', 'volume': '15', 'author': 'Sedighiyan M.', 'year': '2022', 'journal-title': 'BMC Research Notes'}, { 'issue': '1', 'key': 'e_1_2_9_76_1', 'doi-asserted-by': 'crossref', 'first-page': '1004', 'DOI': '10.1080/21691401.2018.1442345', 'article-title': 'Augmentation of therapeutic potential of curcumin using nanotechnology: ' 'Current perspectives', 'volume': '46', 'author': 'Sivasami P.', 'year': '2018', 'journal-title': 'Artificial Cells, Nanomedicine, and Biotechnology'}, { 'issue': '1', 'key': 'e_1_2_9_77_1', 'doi-asserted-by': 'crossref', 'first-page': '415', 'DOI': '10.1016/j.ijpharm.2016.07.027', 'article-title': 'Bioavailability of curcumin and curcumin glucuronide in the central ' 'nervous system of mice after oral delivery of nano‐curcumin', 'volume': '511', 'author': 'Szymusiak M.', 'year': '2016', 'journal-title': 'International Journal of Pharmaceutics'}, { 'issue': '7', 'key': 'e_1_2_9_78_1', 'doi-asserted-by': 'crossref', 'first-page': '5325', 'DOI': '10.1002/jcp.30233', 'article-title': 'Immunomodulatory effects of Nanocurcumin on Th17 cell responses in mild ' 'and severe COVID‐19 patients', 'volume': '236', 'author': 'Tahmasebi S.', 'year': '2021', 'journal-title': 'Journal of Cellular Physiology'}, { 'issue': '2', 'key': 'e_1_2_9_79_1', 'doi-asserted-by': 'crossref', 'first-page': 'e06350', 'DOI': '10.1016/j.heliyon.2021.e06350', 'article-title': 'Antiviral and immunomodulatory activity of curcumin: A case for ' 'prophylactic therapy for COVID‐19', 'volume': '7', 'author': 'Thimmulappa R. K.', 'year': '2021', 'journal-title': 'Heliyon'}, { 'issue': '13', 'key': 'e_1_2_9_80_1', 'doi-asserted-by': 'crossref', 'first-page': '7130', 'DOI': '10.3390/ijms22137130', 'article-title': 'Antimicrobial activity of curcumin in nanoformulations: A comprehensive ' 'review', 'volume': '22', 'author': 'Trigo‐Gutierrez J. K.', 'year': '2021', 'journal-title': 'International Journal of Molecular Sciences'}, { 'issue': '1', 'key': 'e_1_2_9_81_1', 'first-page': '52', 'article-title': 'The effects of nano‐curcumin supplementation on serum level of hs‐CRP, ' 'adhesion molecules, and lipid profiles in hemodialysis patients, a ' 'randomized controlled clinical trial', 'volume': '14', 'author': 'Vafadar_afshar G.', 'year': '2020', 'journal-title': 'Iranian Journal of Kidney Diseases'}, { 'issue': '2', 'key': 'e_1_2_9_82_1', 'doi-asserted-by': 'crossref', 'first-page': '256', 'DOI': '10.3390/nu14020256', 'article-title': 'Effectiveness of curcumin on outcomes of hospitalized COVID‐19 ' 'patients: A systematic review of clinical trials', 'volume': '14', 'author': 'Vahedian‐Azimi A.', 'year': '2022', 'journal-title': 'Nutrients'}, { 'key': 'e_1_2_9_83_1', 'doi-asserted-by': 'publisher', 'DOI': '10.1016/j.intimp.2020.107088'}, { 'issue': '17', 'key': 'e_1_2_9_84_1', 'doi-asserted-by': 'crossref', 'first-page': '4087', 'DOI': '10.1021/jm070295s', 'article-title': 'Specific plant terpenoids and lignoids possess potent antiviral ' 'activities against severe acute respiratory syndrome coronavirus', 'volume': '50', 'author': 'Wen C. C.', 'year': '2007', 'journal-title': 'Journal of Medicinal Chemistry'}, { 'issue': '6', 'key': 'e_1_2_9_85_1', 'doi-asserted-by': 'crossref', 'first-page': '1227', 'DOI': '10.1111/bph.14943', 'article-title': 'Trends in use, pharmacology, and clinical applications of emerging ' 'herbal nutraceuticals', 'volume': '177', 'author': 'Williamson E. M.', 'year': '2020', 'journal-title': 'British Journal of Pharmacology'}, {'key': 'e_1_2_9_86_1', 'doi-asserted-by': 'publisher', 'DOI': '10.2215/cjn.04160320'}, { 'key': 'e_1_2_9_87_1', 'doi-asserted-by': 'publisher', 'DOI': '10.3109/13880209.2012.742116'}, { 'issue': '41', 'key': 'e_1_2_9_88_1', 'doi-asserted-by': 'crossref', 'first-page': '16086', 'DOI': '10.1039/C7NR06520E', 'article-title': 'Synergistic antiviral effect of curcumin functionalized graphene oxide ' 'against respiratory syncytial virus infection', 'volume': '9', 'author': 'Yang X. X.', 'year': '2017', 'journal-title': 'Nanoscale'}, {'key': 'e_1_2_9_89_1', 'doi-asserted-by': 'publisher', 'DOI': '10.1002/ptr.6738'}, {'key': 'e_1_2_9_90_1', 'doi-asserted-by': 'publisher', 'DOI': '10.1126/science.abb3405'}, { 'issue': '8', 'key': 'e_1_2_9_91_1', 'doi-asserted-by': 'crossref', 'first-page': 'e2000171', 'DOI': '10.1002/cbdv.202000171', 'article-title': 'Antibacterial mechanism of curcumin: A review', 'volume': '17', 'author': 'Zheng D.', 'year': '2020', 'journal-title': 'Chemistry & Biodiversity'}], 'container-title': 'Phytotherapy Research', 'original-title': [], 'language': 'en', 'link': [ { 'URL': 'https://onlinelibrary.wiley.com/doi/pdf/10.1002/ptr.7778', 'content-type': 'application/pdf', 'content-version': 'vor', 'intended-application': 'text-mining'}, { 'URL': 'https://onlinelibrary.wiley.com/doi/full-xml/10.1002/ptr.7778', 'content-type': 'application/xml', 'content-version': 'vor', 'intended-application': 'text-mining'}, { 'URL': 'https://onlinelibrary.wiley.com/doi/pdf/10.1002/ptr.7778', 'content-type': 'unspecified', 'content-version': 'vor', 'intended-application': 'similarity-checking'}], 'deposited': { 'date-parts': [[2023, 2, 17]], 'date-time': '2023-02-17T12:15:05Z', 'timestamp': 1676636105000}, 'score': 1, 'resource': {'primary': {'URL': 'https://onlinelibrary.wiley.com/doi/10.1002/ptr.7778'}}, 'subtitle': [], 'short-title': [], 'issued': {'date-parts': [[2023, 2, 17]]}, 'references-count': 90, 'alternative-id': ['10.1002/ptr.7778'], 'URL': 'http://dx.doi.org/10.1002/ptr.7778', 'relation': {}, 'ISSN': ['0951-418X', '1099-1573'], 'subject': ['Pharmacology'], 'container-title-short': 'Phytotherapy Research', 'published': {'date-parts': [[2023, 2, 17]]}, 'assertion': [ { 'value': '2022-07-07', 'order': 0, 'name': 'received', 'label': 'Received', 'group': {'name': 'publication_history', 'label': 'Publication History'}}, { 'value': '2023-01-29', 'order': 1, 'name': 'accepted', 'label': 'Accepted', 'group': {'name': 'publication_history', 'label': 'Publication History'}}, { 'value': '2023-02-17', 'order': 2, 'name': 'published', 'label': 'Published', 'group': {'name': 'publication_history', 'label': 'Publication History'}}]}