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Vitamin D Associated Peculiarities in Women with Mild Covid-19 and Effect of Calcifediol on the Level of Vitamin D and Possibly, on Disease Outcome - Prospective Pilot Study

Karen et al., International Journal of Progressive Science and Technologies, doi:10.52155/ijpsat.v27.2.3269
Feb 2021  
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Vitamin D for COVID-19
8th treatment shown to reduce risk in October 2020
*, now known with p < 0.00000000001 from 120 studies, recognized in 8 countries.
No treatment is 100% effective. Protocols combine complementary and synergistic treatments. * >10% efficacy in meta analysis with ≥3 clinical studies.
4,100+ studies for 60+ treatments.
Prospective study of 30 female COVID-19 patients, all treated with calcifediol on admission, showing significantly increased vitamin D levels with treatment. There was no mortality.
Karen et al., 28 Feb 2021, peer-reviewed, 10 authors.
This PaperVitamin DAll
Vitamin D Associated Peculiarities in Women with Mild Covid-19 and Effect of Calcifediol on the Level of Vitamin D and Possibly, on Disease Outcome -Prospective Pilot Study
Ghambashidze Ketevan, Grigoryan Karen, Mikaberidze Khatia, Ratiani Levan, Goginashvili Nino, Pachkoria Elene, Gabunia Luiza, Sanikidze Tamar, Pkhaladze Maia, Metreveli Levan
biomechanics and information technology 4 .
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Appel, Michos, Mitchell, Blackford, Sternberg et al., Associated Peculiarities in Women with Mild Covid-19 and Effect of Calcifediol on the Level of Vitamin D and Possibly, on Disease Outcome -Prospective Pilot Study
Bouillon, Marcocci, Carmeliet, Bikle, White et al., Skeletal and Extraskeletal Actions of Vitamin D: Current Evidence and Outstanding Questions, Endocrine, doi:10.1210/er.2018-00126
Castillo, Costa, Barrios, Díaz, Miranda et al., Effect of calcifediol treatment and best available therapy versus best available therapy on intensive care unit admission and mortality among patients hospitalized for COVID-19: A pilot randomized clinical study, Journal of Steroid Biochemistry and Molecular Biology, doi:10.1016/j.jsbmb.2020.105751
Charleston, Minotti, Baksh, Christenson, Coresh et al., The Effects of Four Doses of Vitamin D Supplements on Falls in Older Adults, Annals of Internal Medicine, doi:10.7326/m20-3812
Dietrich, Schützt Vitamin D vor schwerem COVID-19? Ein Endokrinologe erklärt die Datenlage und ob eine Supplementierung sinnvoll ist
Fuss, Fassnacht, Vitamin D -Ein kritischer Blick auf die Studienlage Die vermeintlich pleiotrope Wirkung von Vitamin D
Gombart, Pierre, Maggini, A review of micronutrients and the immune system-working in harmony to reduce the risk of infection, Nutrients, doi:10.3390/nu12010236
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Issa, Vitamin D and Type 2 Diabetes Mellitus. In Advances in experimental medicine and biology, pp, Adv Exp Med Biol
Keum, Lee, Greenwood, Manson, Giovannucci, Vitamin D supplementation and total cancer incidence and mortality: A meta-Analysis of randomized controlled trials, Annals, doi:10.1093/annonc/mdz059
Martineau, Jolliffe, Hooper, Greenberg, Aloia et al., Vitamin D supplementation to prevent acute respiratory tract infections: Systematic review and meta-analysis of individual participant data, BMJ (Online, doi:10.1136/bmj.i6583
Merzon, Tworowski, Gorohovski, Vinker, Cohen et al., Low plasma 25(OH) vitamin D level is associated with increased risk of COVID-19 infection: an Israeli population-based study, The FEBS Journal, doi:10.1111/febs.15495
Pham, Waterhouse, Baxter, Romero, Mcleod et al., The effect of vitamin D supplementation on acute respiratory tract infection in older Australian adults: an analysis of data from the D-Health Trial, The Lancet Diabetes and Endocrinology, doi:10.1016/S2213-8587(20)30380-6
Vitamin, Covid-, Evidence reviews for the use of vitamin D supplementation as prevention and treatment of COVID-19 NICE guideline NG187
Zhou, Luo, Qin, Shidoji, The association between Vitamin D deficiency and community-acquired pneumonia: A meta-analysis of observational studies, Medicine, doi:10.1097/MD.0000000000017252
Late treatment
is less effective
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