Analgesics
Antiandrogens
Antihistamines
Azvudine
Bromhexine
Budesonide
Colchicine
Conv. Plasma
Curcumin
Famotidine
Favipiravir
Fluvoxamine
Hydroxychlor..
Ivermectin
Lifestyle
Melatonin
Metformin
Minerals
Molnupiravir
Monoclonals
Naso/orophar..
Nigella Sativa
Nitazoxanide
PPIs
Paxlovid
Quercetin
Remdesivir
Thermotherapy
Vitamins
More

Other
Feedback
Home
 
next
study
previous
study
c19early.org COVID-19 treatment researchZincZinc (more..)
Melatonin Meta
Metformin Meta
Antihistamines Meta
Azvudine Meta Molnupiravir Meta
Bromhexine Meta
Budesonide Meta
Colchicine Meta Nigella Sativa Meta
Conv. Plasma Meta Nitazoxanide Meta
Curcumin Meta PPIs Meta
Famotidine Meta Paxlovid Meta
Favipiravir Meta Quercetin Meta
Fluvoxamine Meta Remdesivir Meta
Hydroxychlor.. Meta Thermotherapy Meta
Ivermectin Meta

All Studies   Meta Analysis       

Patterns of Dietary Supplement Use during the COVID-19 Pandemic in Poland: Focus on Vitamin D and Magnesium

Grosman-Dziewiszek et al., Nutrients, doi:10.3390/nu16193225
Sep 2024  
  Post
  Facebook
Share
  Source   PDF   All Studies   Meta AnalysisMeta
Zinc for COVID-19
2nd treatment shown to reduce risk in July 2020, now with p = 0.00000032 from 46 studies, recognized in 17 countries.
No treatment is 100% effective. Protocols combine treatments.
5,100+ studies for 112 treatments. c19early.org
Survey of 926 Polish pharmacy patients showing a high prevalence of dietary supplemention during the COVID-19 pandemic, with vitamin D and magnesium being the most commonly used. Supplement use was significantly higher among women, those with higher education, and younger age groups (18-30).
Study covers vitamin D, vitamin C, and zinc.
Grosman-Dziewiszek et al., 24 Sep 2024, Poland, peer-reviewed, survey, 4 authors. Contact: izabela.jeskowiak-kossakowska@umw.edu.pl (corresponding author), patrycja.grosman-dziewiszek@umw.edu.pl, adam.szelag@umw.edu.pl, benita.wiatrak@umw.edu.pl.
This PaperZincAll
Patterns of Dietary Supplement Use during the COVID-19 Pandemic in Poland: Focus on Vitamin D and Magnesium
Patrycja Grosman-Dziewiszek, Izabela Jęśkowiak-Kossakowska, Adam Szeląg, Benita Wiatrak
Nutrients, doi:10.3390/nu16193225
Background: The COVID-19 pandemic has brought significant attention to the role of dietary supplements, particularly Vitamin D, in enhancing immunity and possibly mitigating the severity of the disease. The pandemic has highlighted the importance of nutritional health in preventing severe outcomes from infections. Objective: This study aimed to assess consumption patterns of dietary supplements, with a focus on Vitamin D, among the Polish population during the COVID-19 pandemic and to identify the demographic factors influencing these patterns. Methods: An anonymous survey was conducted in March 2021 among 926 pharmacy patients in Poland. The study analyzed the use of dietary supplements such as vitamin D, magnesium, and others in relation to variables like age, gender, and education level. Statistical analyses were performed using the Pearson chi-square test. Results: The study revealed that 77.1% of the respondents reported using dietary supplements, with Vitamin D being the most frequently mentioned, used by 64.6% of participants. Magnesium was also widely used, with a higher overall prevalence of 67.3%, making it the most commonly consumed supplement. The use of supplements was significantly higher among women and individuals with higher education. Younger age groups, particularly those aged 18-30, were more likely to use supplements. Conclusions: The use of supplements was significantly higher among women, individuals with higher education, and those aged 18-30. However, the findings also indicate a growing awareness and increased use across the general population. This trend reflects increased public awareness of the potential health benefits of these supplements in boosting immunity. However, the study also highlights the need for public education on the risks of over-supplementation and the importance of appropriate dosages.
Conflicts of Interest: The authors declare no conflicts of interest.
References
Alshahrani, Aljohani, Vitamin, Deficiency, sufficiency and toxicity, Nutrients, doi:10.3390/nu5093605
Ashraf, Ashraf, Ashraf, Imran, Kalsoom et al., A quadruple blinded placebo controlled randomised trial to evaluate the effectiveness of an Iodine complex for patients with mild to moderate COVID-19 in Pakistan (I-COVID-PK): A structured summary of a study protocol for a randomised controlled trial, Trials, doi:10.1186/s13063-021-05081-3
Benskin, A Basic Review of the Preliminary Evidence That COVID-19 Risk and Severity Is Increased in Vitamin D Deficiency, Front. Public Health, doi:10.3389/fpubh.2020.00513
Bistrian, Parenteral Fish-Oil Emulsions in Critically Ill COVID-19 Emulsions, J. Parenter. Enter. Nutr, doi:10.1002/jpen.1871
Bochenek, Godman, Lipowska, Mikrut, Zuziak et al., Over-the-counter medicine and dietary supplement consumption among academic youth in Poland, Expert Rev. Pharmacoeconomics Outcomes Res, doi:10.1586/14737167.2016.1154790
Bouillon, Manousaki, Rosen, Trajanoska, Rivadeneira et al., The health effects of vitamin D supplementation: Evidence from human studies, Nature reviews, doi:10.1038/s41574-021-00593-z
Brunvoll, Nygaard, Ellingjord-Dale, Holland, Istre et al., Prevention of covid-19 and other acute respiratory infections with cod liver oil supplementation, a low dose vitamin D supplement: Quadruple blinded, randomised placebo controlled trial, BMJ, doi:10.1136/bmj-2022-071245
Chang, Lee, Vitamin D and health-The missing vitamin in humans, Pediatr. Neonatol, doi:10.1016/j.pedneo.2019.04.007
Chinni, El-Khoury, Perera, Bellomo, Jones et al., Zinc supplementation as an adjunct therapy for COVID-19: Challenges and opportunities, Br. J. Clin. Pharmacol, doi:10.1111/bcp.14826
Crowe, Steur, Allen, Appleby, Travis et al., Plasma concentrations of 25-hydroxyvitamin D in meat eaters, fish eaters, vegetarians and vegans: Results from the EPIC-Oxford study, Public Health Nutr, doi:10.1017/S1368980010002454
Dai, Zhu, Manson, Song, Li et al., Magnesium status and supplementation influence vitamin D status and metabolism: Results from a randomized trial, Am. J. Clin. Nutr, doi:10.1093/ajcn/nqy274
Delange, Bürgi, Iodine deficiency disorders in Europe, Bull. World Health Organ
Djuricic, Calder, Beneficial Outcomes of Omega-6 and Omega-3 Polyunsaturated Fatty Acids on Human Health: An Update for 2021, Nutrients, doi:10.3390/nu13072421
Dobson, Cock, Brex, Giovannoni, Vitamin D Supplementation, None, Pract. Neurol, doi:10.1136/practneurol-2017-001720
Durden, Ezaldin, Amos, Kemper, Campbell, Rise in Serum 25-Hydroxyvitamin D Levels during the COVID-19 Pandemic, Nutrients, doi:10.3390/nu16152449
Eyles, Burne, Mcgrath, Vitamin, effects on brain development, adult brain function and the links between low levels of vitamin D and neuropsychiatric disease, Front. Neuroendocrinol, doi:10.1016/j.yfrne.2012.07.001
Fan, Pedersen, Gut microbiota in human metabolic health and disease, Nat. Rev. Microbiol, doi:10.1038/s41579-020-0433-9
Fitero, Bungau, Tit, Endres, Khan et al., Comorbidities, Associated Diseases, and Risk Assessment in COVID-19-A Systematic Review, Int. J. Clin. Pract, doi:10.1155/2022/1571826
Galior, Grebe, Singh, Development of Vitamin D Toxicity from Overcorrection of Vitamin D Deficiency: A Review of Case Reports, Nutrients, doi:10.3390/nu10080953
Galmés, Serra, Palou, Current State of Evidence: Influence of Nutritional and Nutrigenetic Factors on Immunity in the COVID-19 Pandemic Framework, Nutrients, doi:10.3390/nu12092738
Govender, Khaliq, Moodley, Naicker, Insulin resistance in COVID-19 and diabetes, Prim. Care Diabetes, doi:10.1016/j.pcd.2021.04.004
Griffin, Hewison, Hopkin, Kenny, Quinton et al., Vitamin D and COVID-19: Evidence and recommendations for supplementation, R. Soc. Open Sci, doi:10.1098/rsos.201912
Grosman-Dziewiszek, Wiatrak, Jęśkowiak, Szel Ąg, Patients' Habits and the Role of Pharmacists and Telemedicine as Elements of a Modern Health Care System during the COVID-19 Pandemic, J. Clin. Med, doi:10.3390/jcm10184211
Habib, Ibrahim, Zaim, Ibrahim, The role of iron in the pathogenesis of COVID-19 and possible treatment with lactoferrin and other iron chelators, Biomed. Pharmacother. Biomed. Pharmacother, doi:10.1016/j.biopha.2021.111228
Ikonen, Lumme, Seppälä, Pesonen, Piltonen et al., The determinants and longitudinal changes in vitamin D status in middle-age: A Northern Finland Birth Cohort 1966 study, Eur. J. Nutr, doi:10.1007/s00394-021-02606-z
James, Ali, Armitage, Bonell, Cerami et al., The Role of Nutrition in COVID-19 Susceptibility and Severity of Disease: A Systematic Review, J. Nutr, doi:10.1093/jn/nxab059
Jęśkowiak, Wiatrak, Grosman-Dziewiszek, Szel Ąg, The Incidence and Severity of Post-Vaccination Reactions after Vaccination against COVID-19, Vaccines, doi:10.3390/vaccines9050502
Khalesi, Vandelanotte, Thwaite, Russell, Dawson et al., Awareness and Attitudes of Gut Health, Probiotics and Prebiotics in Australian Adults, J. Diet. Suppl, doi:10.1080/19390211.2020.1783420
Kilis-Pstrusinska, Akutko, Braksator, Dancewicz, Grosman-Dziewiszek et al., Kidney Dysfunction and Its Progression in Patients Hospitalized Duo to COVID-19: Contribution to the Clinical Course and Outcomes, J. Clin. Med, doi:10.3390/jcm10235522
Kočovská, Gaughran, Krivoy, Meier, Vitamin-D Deficiency As a Potential Environmental Risk Factor in Multiple Sclerosis, Schizophrenia, and Autism, Front. Psychiatry, doi:10.3389/fpsyt.2017.00047
Kumar, Kubota, Chernov, Kasuya, Potential role of zinc supplementation in prophylaxis and treatment of COVID-19, Med. Hypotheses, doi:10.1016/j.mehy.2020.109848
Manoy, Yuktanandana, Tanavalee, Anomasiri, Ngarmukos et al., Vitamin D Supplementation Improves Quality of Life and Physical Performance in Osteoarthritis Patients, Nutrients, doi:10.3390/nu9080799
Martineau, Jolliffe, Greenberg, Aloia, Bergman et al., Vitamin D supplementation to prevent acute respiratory infections: Individual participant data meta-analysis, Health Technol. Assess, doi:10.3310/hta23020
Mercola, Grant, Wagner, Evidence Regarding Vitamin D and Risk of COVID-19 and Its Severity, Nutrients, doi:10.3390/nu12113361
Muñoz, Grant, Vitamin, Cancer: An Historical Overview of the Epidemiology and Mechanisms, Nutrients, doi:10.3390/nu14071448
Nasser, Naffaa, Mashiach, Azzam, Braun, The association between serum magnesium levels and communityacquired pneumonia 30-day mortality, BMC Infect. Dis, doi:10.1186/s12879-018-3627-2
Nawaz, Ashraf, Ali, Shabbir, Shabbir et al., Renessans Helps in Early Clearance of SARS-CoV-2: In-Vivo Activity of the Iodine Complex in Rhesus macaque, Life, doi:10.3390/life12091424
Nekoukar, Manouchehri, Zakariaei, Accidental vitamin D3 overdose in a young man. International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin-und Ernahrungsforschung, J. Int. Vitaminol. Nutr, doi:10.1024/0300-9831/a000798
Ohaegbulam, Swalih, Patel, Smith, Perrin, Vitamin D Supplementation in COVID-19 Patients: A Clinical Case Series, Am. J. Ther, doi:10.1097/MJT.0000000000001222
Pludowski, Holick, Grant, Konstantynowicz, Mascarenhas et al., Vitamin D supplementation guidelines, J. Steroid Biochem. Mol. Biol, doi:10.1016/j.jsbmb.2017.01.021
Poluektova, Sankova, Volchkova, Larina, Maloletneva et al., The possibility of predicting the COVID-19 severity by clinical-laboratory criteria taking into account the SARS-CoV-2 strain: An analytical review, Epidemiol. Infect. Dis, doi:10.17816/EID629244
Pozo De La Calle, Alonso Ledesma, Nuñez, Castelló Pastor, Lope Carvajal et al., Composition and Nutritional Quality of the Diet in Spanish Households during the First Wave of the COVID-19 Pandemic, Nutrients, doi:10.3390/nu13051443
Read, Obeid, Ahlenstiel, Ahlenstiel, The Role of Zinc in Antiviral Immunity, Adv. Nutr, doi:10.1093/advances/nmz013
Sailike, Onzhanova, Akbay, Tokay, Molnár, Vitamin D in Central Nervous System: Implications for Neurological Disorders, Int. J. Mol. Sci, doi:10.3390/ijms25147809
Soininen, Eloranta, Schwab, Lakka, Sources of vitamin D and determinants of serum 25-hydroxyvitamin D in Finnish adolescents, Eur. J. Nutr, doi:10.1007/s00394-022-03039-y
Staszuk, Wiatrak, Tadeusiewicz, Karuga-Kuźniewska, Rybak, Telerehabilitation approach for patients with hand impairment, Acta Bioeng. Biomech
Szkudlarek, Gębarowski, Hauzer, Wiatrak, The Concept of Health Debt Incurred during the COVID-19 Pandemic on the Example of Basal Cell Skin Cancer Diagnosis in Lower Silesia, J. Clin. Med, doi:10.3390/jcm13164923
Taneri, Gómez-Ochoa, Llanaj, Raguindin, Rojas et al., Anemia and iron metabolism in COVID-19: A systematic review and meta-analysis, Eur. J. Epidemiol, doi:10.1007/s10654-020-00678-5
Tekin, Kılıç, Impact of COVID-19 pandemic on health-promoting lifestyle behaviors: A cross-sectional study, J. Acute Dis, doi:10.4103/2221-6189.369073
Thomas, Patel, Bittel, Wolski, Wang et al., Effect of High-Dose Zinc and Ascorbic Acid Supplementation vs. Usual Care on Symptom Length and Reduction among Ambulatory Patients with SARS-CoV-2 Infection: The COVID A to Z Randomized Clinical Trial, JAMA Netw. Open, doi:10.1001/jamanetworkopen.2021.0369
Trapani, Rosanoff, Baniasadi, Barbagallo, Castiglioni et al., The relevance of magnesium homeostasis in COVID-19, Eur. J. Nutr, doi:10.1007/s00394-021-02704-y
Tsang, Chan, Cho, Yu, Yim et al., An update on COVID-19 pandemic: The epidemiology, pathogenesis, prevention and treatment strategies, Expert Rev. Anti-Infect. Ther, doi:10.1080/14787210.2021.1863146
Venturi, Venturi, Iodine in evolution of salivary glands and in oral health, Nutr. Health, doi:10.1177/026010600902000204
Vyas, Kurian, Bagchi, Manu, Saravu et al., Vitamin D in Prevention and Treatment of COVID-19: Current Perspective and Future Prospects, J. Am. Coll. Nutr, doi:10.1080/07315724.2020.1806758
Wang, Song, Eliassen, Wang, Fung et al., Optimal dietary patterns for prevention of chronic disease, Nat. Med, doi:10.1038/s41591-023-02235-5
Wassif, Alrehely, Alharbi, Aljohani, The Impact of Vitamin D on Neuropsychiatric Disorders, Cureus, doi:10.7759/cureus.47716
Weydert, Vitamin D in Children's Health, Children, doi:10.3390/children1020208
Winder, Kosztyła, Boral, Kocełak, Chudek, The Impact of Iodine Concentration Disorders on Health and Cancer, Nutrients, doi:10.3390/nu14112209
Wróbel, Zastawna, Milewska, Marczak, Kozłowski, Comparison between the American and the European Systems of Monitoring Adverse Effects of Dietary Supplements and Their Usefulness on the Polish Market, Int. J. Environ. Res. Public Health, doi:10.3390/ijerph20020902
Xiang, Xu, Zhan, Lu, Li et al., Association between the Triglyceride-Glucose Index and Vitamin D Status in Type 2 Diabetes Mellitus, Nutrients, doi:10.3390/nu15030639
Žmitek, Hribar, Lavriša, Hristov, Kušar et al., Socio-Demographic and Knowledge-Related Determinants of Vitamin D Supplementation in the Context of the COVID-19 Pandemic: Assessment of an Educational Intervention, Front. Nutr, doi:10.3389/fnut.2021.648450
{ 'indexed': {'date-parts': [[2024, 9, 25]], 'date-time': '2024-09-25T04:28:25Z', 'timestamp': 1727238505257}, 'reference-count': 61, 'publisher': 'MDPI AG', 'issue': '19', 'license': [ { 'start': { 'date-parts': [[2024, 9, 24]], 'date-time': '2024-09-24T00:00:00Z', 'timestamp': 1727136000000}, 'content-version': 'vor', 'delay-in-days': 0, 'URL': 'https://creativecommons.org/licenses/by/4.0/'}], 'content-domain': {'domain': [], 'crossmark-restriction': False}, 'abstract': '<jats:p>Background: The COVID-19 pandemic has brought significant attention to the role of ' 'dietary supplements, particularly Vitamin D, in enhancing immunity and possibly mitigating ' 'the severity of the disease. The pandemic has highlighted the importance of nutritional ' 'health in preventing severe outcomes from infections. Objective: This study aimed to assess ' 'consumption patterns of dietary supplements, with a focus on Vitamin D, among the Polish ' 'population during the COVID-19 pandemic and to identify the demographic factors influencing ' 'these patterns. Methods: An anonymous survey was conducted in March 2021 among 926 pharmacy ' 'patients in Poland. The study analyzed the use of dietary supplements such as vitamin D, ' 'magnesium, and others in relation to variables like age, gender, and education level. ' 'Statistical analyses were performed using the Pearson chi-square test. Results: The study ' 'revealed that 77.1% of the respondents reported using dietary supplements, with Vitamin D ' 'being the most frequently mentioned, used by 64.6% of participants. Magnesium was also widely ' 'used, with a higher overall prevalence of 67.3%, making it the most commonly consumed ' 'supplement. The use of supplements was significantly higher among women and individuals with ' 'higher education. Younger age groups, particularly those aged 18–30, were more likely to use ' 'supplements. Conclusions: The use of supplements was significantly higher among women, ' 'individuals with higher education, and those aged 18–30. However, the findings also indicate ' 'a growing awareness and increased use across the general population. This trend reflects ' 'increased public awareness of the potential health benefits of these supplements in boosting ' 'immunity. However, the study also highlights the need for public education on the risks of ' 'over-supplementation and the importance of appropriate dosages.</jats:p>', 'DOI': '10.3390/nu16193225', 'type': 'journal-article', 'created': {'date-parts': [[2024, 9, 24]], 'date-time': '2024-09-24T12:54:17Z', 'timestamp': 1727182457000}, 'page': '3225', 'source': 'Crossref', 'is-referenced-by-count': 0, 'title': 'Patterns of Dietary Supplement Use during the COVID-19 Pandemic in Poland: Focus on Vitamin D ' 'and Magnesium', 'prefix': '10.3390', 'volume': '16', 'author': [ { 'given': 'Patrycja', 'family': 'Grosman-Dziewiszek', 'sequence': 'first', 'affiliation': [ { 'name': 'Department of Pharmacology, Faculty of Medicine, Wroclaw Medical ' 'University, Mikulicza-Radeckiego 2, 50-345 Wroclaw, Poland'}]}, { 'given': 'Izabela', 'family': 'Jęśkowiak-Kossakowska', 'sequence': 'additional', 'affiliation': [ { 'name': 'Department of Pharmacology, Faculty of Medicine, Wroclaw Medical ' 'University, Mikulicza-Radeckiego 2, 50-345 Wroclaw, Poland'}]}, { 'given': 'Adam', 'family': 'Szeląg', 'sequence': 'additional', 'affiliation': [ { 'name': 'Department of Pharmacology, Faculty of Medicine, Wroclaw Medical ' 'University, Mikulicza-Radeckiego 2, 50-345 Wroclaw, Poland'}]}, { 'ORCID': 'http://orcid.org/0000-0002-1404-2274', 'authenticated-orcid': False, 'given': 'Benita', 'family': 'Wiatrak', 'sequence': 'additional', 'affiliation': [ { 'name': 'Department of Pharmacology, Faculty of Medicine, Wroclaw Medical ' 'University, Mikulicza-Radeckiego 2, 50-345 Wroclaw, Poland'}]}], 'member': '1968', 'published-online': {'date-parts': [[2024, 9, 24]]}, 'reference': [ { 'key': 'ref_1', 'doi-asserted-by': 'crossref', 'unstructured': 'Jęśkowiak, I., Wiatrak, B., Grosman-Dziewiszek, P., and Szeląg, A. ' '(2021). The Incidence and Severity of Post-Vaccination Reactions after ' 'Vaccination against COVID-19. Vaccines, 9.', 'DOI': '10.3390/vaccines9050502'}, { 'key': 'ref_2', 'doi-asserted-by': 'crossref', 'first-page': '877', 'DOI': '10.1080/14787210.2021.1863146', 'article-title': 'An update on COVID-19 pandemic: The epidemiology, pathogenesis, ' 'prevention and treatment strategies', 'volume': '19', 'author': 'Tsang', 'year': '2021', 'journal-title': 'Expert Rev. Anti-Infect. Ther.'}, { 'key': 'ref_3', 'doi-asserted-by': 'crossref', 'unstructured': 'Grosman-Dziewiszek, P., Wiatrak, B., Jęśkowiak, I., and Szeląg, A. ' '(2021). Patients’ Habits and the Role of Pharmacists and Telemedicine as ' 'Elements of a Modern Health Care System during the COVID-19 Pandemic. J. ' 'Clin. Med., 10.', 'DOI': '10.3390/jcm10184211'}, { 'key': 'ref_4', 'doi-asserted-by': 'crossref', 'unstructured': 'Kilis-Pstrusinska, K., Akutko, K., Braksator, J., Dancewicz, A., ' 'Grosman-Dziewiszek, P., Jamer, T., Juszczyńska, K., Konikowska, K., ' 'Koruba, M., and Pupek, M. (2021). Kidney Dysfunction and Its Progression ' 'in Patients Hospitalized Duo to COVID-19: Contribution to the Clinical ' 'Course and Outcomes. J. Clin. Med., 10.', 'DOI': '10.3390/jcm10235522'}, { 'key': 'ref_5', 'doi-asserted-by': 'crossref', 'first-page': '1571826', 'DOI': '10.1155/2022/1571826', 'article-title': 'Comorbidities, Associated Diseases, and Risk Assessment in COVID-19-A ' 'Systematic Review', 'volume': '2022', 'author': 'Fitero', 'year': '2022', 'journal-title': 'Int. J. Clin. Pract.'}, { 'key': 'ref_6', 'doi-asserted-by': 'crossref', 'unstructured': 'Szkudlarek, D., Gębarowski, T., Hauzer, N., and Wiatrak, B. (2024). The ' 'Concept of Health Debt Incurred during the COVID-19 Pandemic on the ' 'Example of Basal Cell Skin Cancer Diagnosis in Lower Silesia. J. Clin. ' 'Med., 13.', 'DOI': '10.3390/jcm13164923'}, { 'key': 'ref_7', 'first-page': '55', 'article-title': 'Telerehabilitation approach for patients with hand impairment', 'volume': '18', 'author': 'Staszuk', 'year': '2016', 'journal-title': 'Acta Bioeng. Biomech.'}, { 'key': 'ref_8', 'doi-asserted-by': 'crossref', 'first-page': '201912', 'DOI': '10.1098/rsos.201912', 'article-title': 'Vitamin D and COVID-19: Evidence and recommendations for ' 'supplementation', 'volume': '7', 'author': 'Griffin', 'year': '2020', 'journal-title': 'R. Soc. Open Sci.'}, { 'key': 'ref_9', 'doi-asserted-by': 'crossref', 'first-page': '340', 'DOI': '10.1017/S1368980010002454', 'article-title': 'Plasma concentrations of 25-hydroxyvitamin D in meat eaters, fish ' 'eaters, vegetarians and vegans: Results from the EPIC-Oxford study', 'volume': '14', 'author': 'Crowe', 'year': '2011', 'journal-title': 'Public Health Nutr.'}, { 'key': 'ref_10', 'first-page': '1011', 'article-title': 'Sources of vitamin D and determinants of serum 25-hydroxyvitamin D in ' 'Finnish adolescents', 'volume': '62', 'author': 'Soininen', 'year': '2023', 'journal-title': 'Eur. J. Nutr.'}, { 'key': 'ref_11', 'doi-asserted-by': 'crossref', 'first-page': '4541', 'DOI': '10.1007/s00394-021-02606-z', 'article-title': 'The determinants and longitudinal changes in vitamin D status in ' 'middle-age: A Northern Finland Birth Cohort 1966 study', 'volume': '60', 'author': 'Ikonen', 'year': '2021', 'journal-title': 'Eur. J. Nutr.'}, { 'key': 'ref_12', 'doi-asserted-by': 'crossref', 'unstructured': 'Manoy, P., Yuktanandana, P., Tanavalee, A., Anomasiri, W., Ngarmukos, ' 'S., Tanpowpong, T., and Honsawek, S. (2017). Vitamin D Supplementation ' 'Improves Quality of Life and Physical Performance in Osteoarthritis ' 'Patients. Nutrients, 9.', 'DOI': '10.3390/nu9080799'}, { 'key': 'ref_13', 'doi-asserted-by': 'crossref', 'first-page': '35', 'DOI': '10.1136/practneurol-2017-001720', 'article-title': 'Vitamin D supplementation', 'volume': '18', 'author': 'Dobson', 'year': '2018', 'journal-title': 'Pract. Neurol.'}, { 'key': 'ref_14', 'doi-asserted-by': 'crossref', 'unstructured': 'Muñoz, A., and Grant, W.B. (2022). Vitamin D and Cancer: An Historical ' 'Overview of the Epidemiology and Mechanisms. Nutrients, 14.', 'DOI': '10.3390/nu14071448'}, { 'key': 'ref_15', 'doi-asserted-by': 'crossref', 'first-page': '1', 'DOI': '10.3310/hta23020', 'article-title': 'Vitamin D supplementation to prevent acute respiratory infections: ' 'Individual participant data meta-analysis', 'volume': '23', 'author': 'Martineau', 'year': '2019', 'journal-title': 'Health Technol. Assess.'}, { 'key': 'ref_16', 'doi-asserted-by': 'crossref', 'first-page': '208', 'DOI': '10.3390/children1020208', 'article-title': 'Vitamin D in Children’s Health', 'volume': '1', 'author': 'Weydert', 'year': '2014', 'journal-title': 'Children'}, { 'key': 'ref_17', 'doi-asserted-by': 'crossref', 'first-page': '237', 'DOI': '10.1016/j.pedneo.2019.04.007', 'article-title': 'Vitamin D and health—The missing vitamin in humans', 'volume': '60', 'author': 'Chang', 'year': '2019', 'journal-title': 'Pediatr. Neonatol.'}, { 'key': 'ref_18', 'doi-asserted-by': 'crossref', 'first-page': '47', 'DOI': '10.1016/j.yfrne.2012.07.001', 'article-title': 'Vitamin D, effects on brain development, adult brain function and the ' 'links between low levels of vitamin D and neuropsychiatric disease', 'volume': '34', 'author': 'Eyles', 'year': '2013', 'journal-title': 'Front. Neuroendocrinol.'}, { 'key': 'ref_19', 'doi-asserted-by': 'crossref', 'unstructured': 'Del Pozo de la Calle, S., Alonso Ledesma, I., Nuñez, O., Castelló ' 'Pastor, A., Lope Carvajal, V., Fernández de Larrea Baz, N., Pérez-Gómez, ' 'B., Pollán, M., and Ruiz Moreno, E. (2021). Composition and Nutritional ' 'Quality of the Diet in Spanish Households during the First Wave of the ' 'COVID-19 Pandemic. Nutrients, 13.', 'DOI': '10.3390/nu13051443'}, { 'key': 'ref_20', 'doi-asserted-by': 'crossref', 'unstructured': 'Kočovská, E., Gaughran, F., Krivoy, A., and Meier, U.C. (2017). ' 'Vitamin-D Deficiency As a Potential Environmental Risk Factor in ' 'Multiple Sclerosis, Schizophrenia, and Autism. Front. Psychiatry, 8.', 'DOI': '10.3389/fpsyt.2017.00047'}, { 'key': 'ref_21', 'doi-asserted-by': 'crossref', 'unstructured': 'Sailike, B., Onzhanova, Z., Akbay, B., Tokay, T., and Molnár, F. (2024). ' 'Vitamin D in Central Nervous System: Implications for Neurological ' 'Disorders. Int. J. Mol. Sci., 25.', 'DOI': '10.3390/ijms25147809'}, { 'key': 'ref_22', 'first-page': 'e47716', 'article-title': 'The Impact of Vitamin D on Neuropsychiatric Disorders', 'volume': '15', 'author': 'Wassif', 'year': '2023', 'journal-title': 'Cureus'}, { 'key': 'ref_23', 'doi-asserted-by': 'crossref', 'first-page': 'e485', 'DOI': '10.1097/MJT.0000000000001222', 'article-title': 'Vitamin D Supplementation in COVID-19 Patients: A Clinical Case Series', 'volume': '27', 'author': 'Ohaegbulam', 'year': '2020', 'journal-title': 'Am. J. Ther.'}, { 'key': 'ref_24', 'first-page': '96', 'article-title': 'The health effects of vitamin D supplementation: Evidence from human ' 'studies. Nature reviews', 'volume': '18', 'author': 'Bouillon', 'year': '2022', 'journal-title': 'Endocrinology'}, { 'key': 'ref_25', 'doi-asserted-by': 'crossref', 'unstructured': 'Benskin, L.L. (2020). A Basic Review of the Preliminary Evidence That ' 'COVID-19 Risk and Severity Is Increased in Vitamin D Deficiency. Front. ' 'Public Health, 8.', 'DOI': '10.3389/fpubh.2020.00513'}, { 'key': 'ref_26', 'doi-asserted-by': 'crossref', 'first-page': '632', 'DOI': '10.1080/07315724.2020.1806758', 'article-title': 'Vitamin D in Prevention and Treatment of COVID-19: Current Perspective ' 'and Future Prospects', 'volume': '40', 'author': 'Vyas', 'year': '2021', 'journal-title': 'J. Am. Coll. Nutr.'}, { 'key': 'ref_27', 'doi-asserted-by': 'crossref', 'unstructured': 'Žmitek, K., Hribar, M., Lavriša, Ž., Hristov, H., Kušar, A., and Pravst, ' 'I. (2021). Socio-Demographic and Knowledge-Related Determinants of ' 'Vitamin D Supplementation in the Context of the COVID-19 Pandemic: ' 'Assessment of an Educational Intervention. Front. Nutr., 8.', 'DOI': '10.3389/fnut.2021.648450'}, { 'key': 'ref_28', 'doi-asserted-by': 'crossref', 'first-page': '10', 'DOI': '10.4103/2221-6189.369073', 'article-title': 'Impact of COVID-19 pandemic on health-promoting lifestyle behaviors: A ' 'cross-sectional study', 'volume': '12', 'author': 'Tekin', 'year': '2023', 'journal-title': 'J. Acute Dis.'}, { 'key': 'ref_29', 'doi-asserted-by': 'crossref', 'first-page': '418', 'DOI': '10.1080/19390211.2020.1783420', 'article-title': 'Awareness and Attitudes of Gut Health, Probiotics and Prebiotics in ' 'Australian Adults', 'volume': '18', 'author': 'Khalesi', 'year': '2021', 'journal-title': 'J. Diet. Suppl.'}, { 'key': 'ref_30', 'first-page': '192', 'article-title': 'The possibility of predicting the COVID-19 severity by ' 'clinical-laboratory criteria taking into account the SARS-CoV-2 strain: ' 'An analytical review', 'volume': '29', 'author': 'Poluektova', 'year': '2024', 'journal-title': 'Epidemiol. Infect. Dis.'}, { 'key': 'ref_31', 'doi-asserted-by': 'crossref', 'unstructured': 'Durden, W., Ezaldin, S., Amos, J., Kemper, S., and Campbell, J. (2024). ' 'Rise in Serum 25-Hydroxyvitamin D Levels during the COVID-19 Pandemic. ' 'Nutrients, 16.', 'DOI': '10.3390/nu16152449'}, { 'key': 'ref_32', 'doi-asserted-by': 'crossref', 'first-page': '82', 'DOI': '10.1024/0300-9831/a000798', 'article-title': 'Accidental vitamin D3 overdose in a young man. International journal ' 'for vitamin and nutrition research. Internationale Zeitschrift fur ' 'Vitamin- und Ernahrungsforschung', 'volume': '94', 'author': 'Nekoukar', 'year': '2024', 'journal-title': 'J. Int. Vitaminol. Nutr.'}, { 'key': 'ref_33', 'doi-asserted-by': 'crossref', 'first-page': '3605', 'DOI': '10.3390/nu5093605', 'article-title': 'Vitamin D: Deficiency, sufficiency and toxicity', 'volume': '5', 'author': 'Alshahrani', 'year': '2013', 'journal-title': 'Nutrients'}, { 'key': 'ref_34', 'doi-asserted-by': 'crossref', 'unstructured': 'Galior, K., Grebe, S., and Singh, R. (2018). Development of Vitamin D ' 'Toxicity from Overcorrection of Vitamin D Deficiency: A Review of Case ' 'Reports. Nutrients, 10.', 'DOI': '10.3390/nu10080953'}, { 'key': 'ref_35', 'doi-asserted-by': 'crossref', 'first-page': '125', 'DOI': '10.1016/j.jsbmb.2017.01.021', 'article-title': 'Vitamin D supplementation guidelines', 'volume': '175', 'author': 'Pludowski', 'year': '2018', 'journal-title': 'J. Steroid Biochem. Mol. Biol.'}, { 'key': 'ref_36', 'doi-asserted-by': 'crossref', 'unstructured': 'Mercola, J., Grant, W.B., and Wagner, C.L. (2020). Evidence Regarding ' 'Vitamin D and Risk of COVID-19 and Its Severity. Nutrients, 12.', 'DOI': '10.3390/nu12113361'}, { 'key': 'ref_37', 'doi-asserted-by': 'crossref', 'first-page': '629', 'DOI': '10.1016/j.pcd.2021.04.004', 'article-title': 'Insulin resistance in COVID-19 and diabetes', 'volume': '15', 'author': 'Govender', 'year': '2021', 'journal-title': 'Prim. Care Diabetes'}, { 'key': 'ref_38', 'doi-asserted-by': 'crossref', 'first-page': '719', 'DOI': '10.1038/s41591-023-02235-5', 'article-title': 'Optimal dietary patterns for prevention of chronic disease', 'volume': '29', 'author': 'Wang', 'year': '2023', 'journal-title': 'Nat. Med.'}, { 'key': 'ref_39', 'doi-asserted-by': 'crossref', 'unstructured': 'Xiang, Q., Xu, H., Zhan, J., Lu, S., Li, S., Wang, Y., Wang, Y., He, J., ' 'Ni, Y., and Li, L. (2023). Association between the Triglyceride-Glucose ' 'Index and Vitamin D Status in Type 2 Diabetes Mellitus. Nutrients, 15.', 'DOI': '10.3390/nu15030639'}, { 'key': 'ref_40', 'doi-asserted-by': 'crossref', 'first-page': '625', 'DOI': '10.1007/s00394-021-02704-y', 'article-title': 'The relevance of magnesium homeostasis in COVID-19', 'volume': '61', 'author': 'Trapani', 'year': '2022', 'journal-title': 'Eur. J. Nutr.'}, { 'key': 'ref_41', 'doi-asserted-by': 'crossref', 'first-page': '1249', 'DOI': '10.1093/ajcn/nqy274', 'article-title': 'Magnesium status and supplementation influence vitamin D status and ' 'metabolism: Results from a randomized trial', 'volume': '108', 'author': 'Dai', 'year': '2018', 'journal-title': 'Am. J. Clin. Nutr.'}, { 'key': 'ref_42', 'doi-asserted-by': 'crossref', 'unstructured': 'Nasser, R., Naffaa, M.E., Mashiach, T., Azzam, Z.S., and Braun, E. ' '(2018). The association between serum magnesium levels and ' 'community-acquired pneumonia 30-day mortality. BMC Infect. Dis., 18.', 'DOI': '10.1186/s12879-018-3627-2'}, { 'key': 'ref_43', 'doi-asserted-by': 'crossref', 'first-page': '3737', 'DOI': '10.1111/bcp.14826', 'article-title': 'Zinc supplementation as an adjunct therapy for COVID-19: Challenges and ' 'opportunities', 'volume': '87', 'author': 'Chinni', 'year': '2021', 'journal-title': 'Br. J. Clin. Pharmacol.'}, { 'key': 'ref_44', 'doi-asserted-by': 'crossref', 'first-page': 'e210369', 'DOI': '10.1001/jamanetworkopen.2021.0369', 'article-title': 'Effect of High-Dose Zinc and Ascorbic Acid Supplementation vs. Usual ' 'Care on Symptom Length and Reduction among Ambulatory Patients with ' 'SARS-CoV-2 Infection: The COVID A to Z Randomized Clinical Trial', 'volume': '4', 'author': 'Thomas', 'year': '2021', 'journal-title': 'JAMA Netw. Open'}, { 'key': 'ref_45', 'doi-asserted-by': 'crossref', 'first-page': '696', 'DOI': '10.1093/advances/nmz013', 'article-title': 'The Role of Zinc in Antiviral Immunity', 'volume': '10', 'author': 'Read', 'year': '2019', 'journal-title': 'Adv. Nutr.'}, { 'key': 'ref_46', 'doi-asserted-by': 'crossref', 'first-page': '109848', 'DOI': '10.1016/j.mehy.2020.109848', 'article-title': 'Potential role of zinc supplementation in prophylaxis and treatment of ' 'COVID-19', 'volume': '144', 'author': 'Kumar', 'year': '2020', 'journal-title': 'Med. Hypotheses'}, { 'key': 'ref_47', 'doi-asserted-by': 'crossref', 'first-page': '1854', 'DOI': '10.1093/jn/nxab059', 'article-title': 'The Role of Nutrition in COVID-19 Susceptibility and Severity of ' 'Disease: A Systematic Review', 'volume': '151', 'author': 'James', 'year': '2021', 'journal-title': 'J. Nutr.'}, { 'key': 'ref_48', 'doi-asserted-by': 'crossref', 'unstructured': 'Galmés, S., Serra, F., and Palou, A. (2020). Current State of Evidence: ' 'Influence of Nutritional and Nutrigenetic Factors on Immunity in the ' 'COVID-19 Pandemic Framework. Nutrients, 12.', 'DOI': '10.3390/nu12092738'}, { 'key': 'ref_49', 'doi-asserted-by': 'crossref', 'unstructured': 'Habib, H.M., Ibrahim, S., Zaim, A., and Ibrahim, W.H. (2021). The role ' 'of iron in the pathogenesis of COVID-19 and possible treatment with ' 'lactoferrin and other iron chelators. Biomed. Pharmacother. Biomed. ' 'Pharmacother., 136.', 'DOI': '10.1016/j.biopha.2021.111228'}, { 'key': 'ref_50', 'doi-asserted-by': 'crossref', 'first-page': '763', 'DOI': '10.1007/s10654-020-00678-5', 'article-title': 'Anemia and iron metabolism in COVID-19: A systematic review and ' 'meta-analysis', 'volume': '35', 'author': 'Taneri', 'year': '2020', 'journal-title': 'Eur. J. Epidemiol.'}, { 'key': 'ref_51', 'doi-asserted-by': 'crossref', 'first-page': '119', 'DOI': '10.1177/026010600902000204', 'article-title': 'Iodine in evolution of salivary glands and in oral health', 'volume': '20', 'author': 'Venturi', 'year': '2009', 'journal-title': 'Nutr. Health'}, { 'key': 'ref_52', 'first-page': '317', 'article-title': 'Iodine deficiency disorders in Europe', 'volume': '67', 'author': 'Delange', 'year': '1989', 'journal-title': 'Bull. World Health Organ.'}, { 'key': 'ref_53', 'doi-asserted-by': 'crossref', 'unstructured': 'Winder, M., Kosztyła, Z., Boral, A., Kocełak, P., and Chudek, J. (2022). ' 'The Impact of Iodine Concentration Disorders on Health and Cancer. ' 'Nutrients, 14.', 'DOI': '10.3390/nu14112209'}, { 'key': 'ref_54', 'doi-asserted-by': 'crossref', 'unstructured': 'Nawaz, M., Ashraf, M.A., Ali, M.A., Shabbir, M.Z., Shabbir, M.A.B., ' 'Altaf, I., Raza, S., Rafique, S., Hassan, S., and Sardar, N. (2022). ' 'Renessans Helps in Early Clearance of SARS-CoV-2: In-Vivo Activity of ' 'the Iodine Complex in Rhesus macaque. Life, 12.', 'DOI': '10.3390/life12091424'}, { 'key': 'ref_55', 'doi-asserted-by': 'crossref', 'first-page': '127', 'DOI': '10.1186/s13063-021-05081-3', 'article-title': 'A quadruple blinded placebo controlled randomised trial to evaluate the ' 'effectiveness of an Iodine complex for patients with mild to moderate ' 'COVID-19 in Pakistan (I-COVID-PK): A structured summary of a study ' 'protocol for a randomised controlled trial', 'volume': '22', 'author': 'Ashraf', 'year': '2021', 'journal-title': 'Trials'}, { 'key': 'ref_56', 'doi-asserted-by': 'crossref', 'unstructured': 'Djuricic, I., and Calder, P.C. (2021). Beneficial Outcomes of Omega-6 ' 'and Omega-3 Polyunsaturated Fatty Acids on Human Health: An Update for ' '2021. Nutrients, 13.', 'DOI': '10.3390/nu13072421'}, { 'key': 'ref_57', 'doi-asserted-by': 'crossref', 'first-page': 'e071245', 'DOI': '10.1136/bmj-2022-071245', 'article-title': 'Prevention of covid-19 and other acute respiratory infections with cod ' 'liver oil supplementation, a low dose vitamin D supplement: Quadruple ' 'blinded, randomised placebo controlled trial', 'volume': '378', 'author': 'Brunvoll', 'year': '2022', 'journal-title': 'BMJ'}, { 'key': 'ref_58', 'doi-asserted-by': 'crossref', 'first-page': '55', 'DOI': '10.1038/s41579-020-0433-9', 'article-title': 'Gut microbiota in human metabolic health and disease', 'volume': '19', 'author': 'Fan', 'year': '2021', 'journal-title': 'Nat. Rev. Microbiol.'}, { 'key': 'ref_59', 'doi-asserted-by': 'crossref', 'first-page': '1168', 'DOI': '10.1002/jpen.1871', 'article-title': 'Parenteral Fish-Oil Emulsions in Critically Ill COVID-19 Emulsions', 'volume': '44', 'author': 'Bistrian', 'year': '2020', 'journal-title': 'J. Parenter. Enter. Nutr.'}, { 'key': 'ref_60', 'doi-asserted-by': 'crossref', 'first-page': '199', 'DOI': '10.1586/14737167.2016.1154790', 'article-title': 'Over-the-counter medicine and dietary supplement consumption among ' 'academic youth in Poland', 'volume': '16', 'author': 'Bochenek', 'year': '2016', 'journal-title': 'Expert Rev. Pharmacoeconomics Outcomes Res.'}, { 'key': 'ref_61', 'doi-asserted-by': 'crossref', 'unstructured': 'Wróbel, K., Zastawna, B., Milewska, A.J., Marczak, M., and Kozłowski, R. ' '(2023). Comparison between the American and the European Systems of ' 'Monitoring Adverse Effects of Dietary Supplements and Their Usefulness ' 'on the Polish Market. Int. J. Environ. Res. Public Health, 20.', 'DOI': '10.3390/ijerph20020902'}], 'container-title': 'Nutrients', 'original-title': [], 'language': 'en', 'link': [ { 'URL': 'https://www.mdpi.com/2072-6643/16/19/3225/pdf', 'content-type': 'unspecified', 'content-version': 'vor', 'intended-application': 'similarity-checking'}], 'deposited': { 'date-parts': [[2024, 9, 24]], 'date-time': '2024-09-24T13:29:57Z', 'timestamp': 1727184597000}, 'score': 1, 'resource': {'primary': {'URL': 'https://www.mdpi.com/2072-6643/16/19/3225'}}, 'subtitle': [], 'short-title': [], 'issued': {'date-parts': [[2024, 9, 24]]}, 'references-count': 61, 'journal-issue': {'issue': '19', 'published-online': {'date-parts': [[2024, 10]]}}, 'alternative-id': ['nu16193225'], 'URL': 'http://dx.doi.org/10.3390/nu16193225', 'relation': {}, 'ISSN': ['2072-6643'], 'subject': [], 'container-title-short': 'Nutrients', 'published': {'date-parts': [[2024, 9, 24]]}}
Loading..
Please send us corrections, updates, or comments. c19early involves the extraction of 100,000+ datapoints from thousands of papers. Community updates help ensure high accuracy. Treatments and other interventions are complementary. All practical, effective, and safe means should be used based on risk/benefit analysis. No treatment or intervention is 100% available and effective for all current and future variants. We do not provide medical advice. Before taking any medication, consult a qualified physician who can provide personalized advice and details of risks and benefits based on your medical history and situation. FLCCC and WCH provide treatment protocols.
  or use drag and drop   
Submit