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0 0.5 1 1.5 2+ Symptomatic case 25% Improvement Relative Risk c19early.org/d González-Estevez et al. Vitamin D Sufficiency Are vitamin D levels associated with COVID-19 outcomes? Retrospective 40 patients in Mexico Fewer symptomatic cases with higher vitamin D levels (p=0.036) González-Estevez et al., Int. J. Environmental R.., doi:10.3390/ijerph18147266 Favors vitamin D Favors control
Association of Food Intake Quality with Vitamin D in SARS-CoV-2 Positive Patients from Mexico: A Cross-Sectional Study
González-Estevez et al., International Journal of Environmental Research and Public Health, doi:10.3390/ijerph18147266
González-Estevez et al., Association of Food Intake Quality with Vitamin D in SARS-CoV-2 Positive Patients from Mexico: A.., International Journal of Environmental Research and Public Health, doi:10.3390/ijerph18147266
Jul 2021   Source   PDF  
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Retrospective 40 COVID+ patients in Mexico, showing higher risk of symptoms with vitamin D deficiency. Higher food intake quality and intense physical activity were associated with vitamin D sufficiency. Insufficient intake of several micronutrients was common.
risk of symptomatic case, 25.0% lower, RR 0.75, p = 0.04, high D levels (≥30ng/mL) 6 of 8 (75.0%), low D levels (<30ng/mL) 32 of 32 (100.0%), NNT 4.0.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
González-Estevez et al., 7 Jul 2021, retrospective, Mexico, peer-reviewed, 6 authors.
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Abstract: International Journal of Environmental Research and Public Health Article Association of Food Intake Quality with Vitamin D in SARS-CoV-2 Positive Patients from Mexico: A Cross-Sectional Study Guillermo González-Estevez 1,2 , Francisco Javier Turrubiates-Hernández 1 , Laura Elena Herrera-Jiménez 1 , Gabriela Athziri Sánchez-Zuno 1 , Melva Guadalupe Herrera-Godina 1 and José Francisco Muñoz-Valle 1,2, * 1 2 *   Citation: González-Estevez, G.; Turrubiates-Hernández, F.J.; Herrera-Jiménez, L.E.; Sánchez-Zuno, G.A.; Herrera-Godina, M.G.; Muñoz-Valle, J.F. Association of Food Intake Quality with Vitamin D in SARS-CoV-2 Positive Patients from Mexico: A Cross-Sectional Study. Int. J. Environ. Res. Public Health 2021, 18, 7266. https://doi.org/10.3390/ ijerph18147266 Academic Editor: Paul B. Tchounwou Received: 10 June 2021 Institute of Research in Biomedical Sciences, Department of Medical Clinics, University Center of Health Sciences (CUCS), University of Guadalajara, Edificio Q, 950 Sierra Mojada, Guadalajara 44340, Mexico; guillermo.gonzalezestevez@cucs.udg.mx (G.G.-E.); francisco.turrubiates3337@alumnos.udg.mx (F.J.T.-H.); laura.herrera3967@alumnos.udg.mx (L.E.H.-J.); athziri.sanchez@alumnos.udg.mx (G.A.S.-Z.); melva.herrera@academicos.udg.mx (M.G.H.-G.) COVID-19 Situation Room (Analysis Group), University Center of Health Sciences (CUCS), University of Guadalajara, Guadalajara 44340, Mexico Correspondence: biologiamolecular@hotmail.com or drjosefranciscomv@cucs.udg.mx Abstract: One of the micronutrients that has attracted the most attention in relation to COVID-19 is vitamin D. Although several factors affect its sufficiency; it has been argued that an optimal diet can ensure the intake of micronutrients with effects on immune response. Therefore, in this work we aimed to evaluate the food intake quality of SARS-CoV-2 positive Mexican patients and some of the common factors related to vitamin D deficiency. We conducted a cross-sectional study in 40 SARSCoV-2 positive patients. Serum samples and clinical parameters were collected. Micronutrient intake and food intake quality were assessed with a 24-h dietary recall and the Mini-ECCA v.2, respectively. Thirty-eight percent of the sample had a healthy food intake. The median 25(OH)D concentration was 22.7 ng/mL. A considerable insufficient intake of micronutrients with immunomodulatory effects such as vitamin D (p < 0.0001), vitamin E (p < 0.0001), and zinc (p < 0.0001) was shown. Patients with 25(OH)D sufficiency, defined as a concentration >30 ng/mL, had better food intake quality (p = 0.02) and an intense physical activity (p = 0.03). In conclusion, a better level of food intake quality and intense physical activity are associated with 25(OH)D sufficiency in SARS-CoV-2 positive Mexican patients. Keywords: vitamin D; SARS-CoV-2; food intake quality; physical activity; COVID-19; coronavirus; calcidiol; micronutrients; Mexico Accepted: 4 July 2021 Published: 7 July 2021 Publisher’s Note: MDPI stays neutral with regard to jurisdictional claims in published maps and institutional affiliations. Copyright: © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https:// creativecommons.org/licenses/by/ 4.0/).
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