M Brown, J Gahir, Simpson, K Elgizouli, 10 Marks, Michael Marks, Anna Goodman
doi:10.1093/ofid/ofac527/6750023
Title
Demographics and outcomes of initial phase of COVID-19 Medicines Delivery Units across 4 UK centres during peak B1.1.529 omicron epidemic: a service evaluation.
Funding No specific funding for this work. MM is supported by NIHR and the EDCTP.
Conflict of Interest The authors have no conflicts of interest to declare
References
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'abstract': '<jats:title>Abstract</jats:title>\n'
' <jats:sec>\n'
' <jats:title>Introduction</jats:title>\n'
' <jats:p>COVID-19 Medicine Delivery Units (CMDU) were established in late '
'December 2021 to deliver early antiviral therapy to patients classified as at risk with the '
'aim of preventing hospitalisation.</jats:p>\n'
' </jats:sec>\n'
' <jats:sec>\n'
' <jats:title>Methods</jats:title>\n'
' <jats:p>We performed a service evaluation at four CMDUs in England. We '
'assessed demographics and triage outcomes of CMDU referral, uptake of antiviral therapy and '
'the rate of subsequent hospitalisations within two weeks of CMDU referral.</jats:p>\n'
' </jats:sec>\n'
' <jats:sec>\n'
' <jats:title>Results</jats:title>\n'
' <jats:p>Over a three week period 4,788 patients were referred and 3,989 '
'were ultimately assessed by a CMDU. Overall, 832 of the patients referred (17%) were judged '
'eligible for treatment and 628 (13%) were ultimately prescribed an antiviral agent. The '
'overall rate of admission within 14 days was 1%. Patients who were admitted were '
'significantly older than those who did not require hospitalisation. Of patients prescribed '
'molnupiravir and sotrovimab 1.8% and 3.2% were admitted respectively.</jats:p>\n'
' </jats:sec>\n'
' <jats:sec>\n'
' <jats:title>Conclusion</jats:title>\n'
' <jats:p>There were a high volume of referrals to CMDU service during the '
'the initial surge of the Omicron wave in the UK. A minority of patients were judged to be '
'eligible for therapy. In a highly vaccinated population, the overall hospitalisation rate was '
'low.</jats:p>\n'
' </jats:sec>',
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'title': 'Demographics and outcomes of initial phase of COVID-19 Medicines Delivery Units across 4 UK '
'centres during peak B1.1.529 omicron epidemic: a service evaluation.',
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