Metformin use before COVID-19 vaccination and the risks of COVID-19 incidence, medical utilization, and all-cause mortality in patients with type 2 diabetes mellitus

DOI record: { "DOI": "10.1016/j.diabres.2023.110692", "ISSN": [ "0168-8227" ], "URL": "http://dx.doi.org/10.1016/j.diabres.2023.110692", "alternative-id": [ "S0168822723004540" ], "article-number": "110692", "assertion": [ { "label": "This article is maintained by", "name": "publisher", "value": "Elsevier" }, { "label": "Article Title", "name": "articletitle", "value": "Metformin use before COVID-19 vaccination and the risks of COVID-19 incidence, medical utilization, and all-cause mortality in patients with type 2 diabetes mellitus" }, { "label": "Journal Title", "name": "journaltitle", "value": "Diabetes Research and Clinical Practice" }, { "label": "CrossRef DOI link to publisher maintained version", "name": "articlelink", "value": "https://doi.org/10.1016/j.diabres.2023.110692" }, { "label": "Content Type", "name": "content_type", "value": "article" }, { "label": "Copyright", "name": "copyright", "value": "© 2023 Published by Elsevier B.V." } ], "author": [ { "affiliation": [], "family": "Yen", "given": "Fu-Shun", "sequence": "first" }, { "affiliation": [], "family": "Wang", "given": "Shiow-Ing", "sequence": "additional" }, { "affiliation": [], "family": "Lin", "given": "Shih-Yi", "sequence": "additional" }, { "affiliation": [], "family": "Cheng-Chung Wei", "given": "James", "sequence": "additional" } ], "container-title": "Diabetes Research and Clinical Practice", "container-title-short": "Diabetes Research and Clinical Practice", "content-domain": { "crossmark-restriction": true, "domain": [ "clinicalkey.fr", "clinicalkey.jp", "diabetesresearchclinicalpractice.com", "clinicalkey.es", "clinicalkey.com.au", "clinicalkey.com", "elsevier.com", "sciencedirect.com" ] }, "created": { "date-parts": [ [ 2023, 5, 6 ] ], "date-time": "2023-05-06T15:03:35Z", "timestamp": 1683385415000 }, "deposited": { "date-parts": [ [ 2023, 5, 6 ] ], "date-time": "2023-05-06T15:03:50Z", "timestamp": 1683385430000 }, "indexed": { "date-parts": [ [ 2023, 5, 7 ] ], "date-time": "2023-05-07T04:24:00Z", "timestamp": 1683433440124 }, "is-referenced-by-count": 0, "issued": { "date-parts": [ [ 2023, 5 ] ] }, "language": "en", "license": [ { "URL": "https://www.elsevier.com/tdm/userlicense/1.0/", "content-version": "tdm", "delay-in-days": 0, "start": { "date-parts": [ [ 2023, 5, 1 ] ], "date-time": "2023-05-01T00:00:00Z", "timestamp": 1682899200000 } }, { "URL": "https://doi.org/10.15223/policy-017", "content-version": "stm-asf", "delay-in-days": 0, "start": { "date-parts": [ [ 2023, 5, 1 ] ], "date-time": "2023-05-01T00:00:00Z", "timestamp": 1682899200000 } }, { "URL": "https://doi.org/10.15223/policy-037", "content-version": "stm-asf", "delay-in-days": 0, "start": { "date-parts": [ [ 2023, 5, 1 ] ], "date-time": "2023-05-01T00:00:00Z", "timestamp": 1682899200000 } }, { "URL": "https://doi.org/10.15223/policy-012", "content-version": "stm-asf", "delay-in-days": 0, "start": { "date-parts": [ [ 2023, 5, 1 ] ], "date-time": "2023-05-01T00:00:00Z", "timestamp": 1682899200000 } }, { "URL": "https://doi.org/10.15223/policy-029", "content-version": "stm-asf", "delay-in-days": 0, "start": { "date-parts": [ [ 2023, 5, 1 ] ], "date-time": "2023-05-01T00:00:00Z", "timestamp": 1682899200000 } }, { "URL": "https://doi.org/10.15223/policy-004", "content-version": "stm-asf", "delay-in-days": 0, "start": { "date-parts": [ [ 2023, 5, 1 ] ], "date-time": "2023-05-01T00:00:00Z", "timestamp": 1682899200000 } } ], "link": [ { "URL": "https://api.elsevier.com/content/article/PII:S0168822723004540?httpAccept=text/xml", "content-type": "text/xml", "content-version": "vor", "intended-application": "text-mining" }, { "URL": "https://api.elsevier.com/content/article/PII:S0168822723004540?httpAccept=text/plain", "content-type": "text/plain", "content-version": "vor", "intended-application": "text-mining" } ], "member": "78", "original-title": [], "page": "110692", "prefix": "10.1016", "published": { "date-parts": [ [ 2023, 5 ] ] }, "published-print": { "date-parts": [ [ 2023, 5 ] ] }, "publisher": "Elsevier BV", "reference": [ { "DOI": "10.1126/science.abm4915", "article-title": "The changing epidemiology of SARS-CoV-2", "author": "Koelle", "doi-asserted-by": "crossref", "first-page": "1116", "journal-title": "Science", "key": "10.1016/j.diabres.2023.110692_b0005", "volume": "375", "year": "2022" }, { "key": "10.1016/j.diabres.2023.110692_b0010", "unstructured": "World Health Organization (WHO). WHO Coronavirus (COVID-19) dashboard, https://covid19.who.int/table; 2022 [accessed 16 December 2022]." }, { "DOI": "10.1126/science.abn1900", "article-title": "Stopping pandemics before they start: lessons learned from SARS-CoV-2", "author": "Edwards", "doi-asserted-by": "crossref", "first-page": "1133", "journal-title": "Science", "key": "10.1016/j.diabres.2023.110692_b0015", "volume": "375", "year": "2022" }, { "DOI": "10.1016/j.dsx.2021.02.026", "article-title": "COVID-19 vaccination in patients with diabetes mellitus: current concepts, uncertainties and challenges", "author": "Pal", "doi-asserted-by": "crossref", "first-page": "505", "journal-title": "Diabetes Metab Syndr", "key": "10.1016/j.diabres.2023.110692_b0020", "volume": "15", "year": "2021" }, { "DOI": "10.1016/S2213-8587(20)30152-2", "article-title": "Practical recommendations for the management of diabetes in patients with COVID-19", "author": "Bornstein", "doi-asserted-by": "crossref", "first-page": "546", "journal-title": "Lancet Diabetes Endocrinol", "key": "10.1016/j.diabres.2023.110692_b0025", "volume": "8", "year": "2020" }, { "DOI": "10.1056/NEJMra2206573", "article-title": "Covid-19 vaccines - immunity, variants, boosters", "author": "Barouch", "doi-asserted-by": "crossref", "first-page": "1011", "journal-title": "N Engl J Med", "key": "10.1016/j.diabres.2023.110692_b0030", "volume": "387", "year": "2022" }, { "DOI": "10.1038/s41574-020-00435-4", "article-title": "COVID-19 and diabetes mellitus: from pathophysiology to clinical management", "author": "Lim", "doi-asserted-by": "crossref", "first-page": "11", "journal-title": "Nat Rev Endocrinol", "key": "10.1016/j.diabres.2023.110692_b0035", "volume": "17", "year": "2021" }, { "DOI": "10.2337/dc22-S004", "doi-asserted-by": "crossref", "key": "10.1016/j.diabres.2023.110692_b0040", "unstructured": "American Diabetes Association Professional Practice Committee; American Diabetes Association Professional Practice Committee; Draznin B, Aroda VR, Bakris G, Benson G, et al. 4. Comprehensive medical evaluation and assessment of comorbidities: standards of medical care in diabetes-2022. Diabetes Care 2022;45:S46–59. https://doi.org/10.2337/dc22-S004." }, { "DOI": "10.1111/dom.14547", "article-title": "Does poor glycaemic control affect the immunogenicity of the COVID-19 vaccination in patients with type 2 diabetes: the CAVEAT study", "author": "Marfella", "doi-asserted-by": "crossref", "first-page": "160", "journal-title": "Diabetes Obes Metab", "key": "10.1016/j.diabres.2023.110692_b0045", "volume": "24", "year": "2022" }, { "DOI": "10.1007/s00125-020-05284-4", "article-title": "Antibody response to multiple antigens of SARS-CoV-2 in patients with diabetes: an observational cohort study", "author": "Lampasona", "doi-asserted-by": "crossref", "first-page": "2548", "journal-title": "Diabetologia", "key": "10.1016/j.diabres.2023.110692_b0050", "volume": "63", "year": "2020" }, { "DOI": "10.1210/clinem/dgab055", "article-title": "Robust neutralizing antibodies to SARS-CoV-2 develop and persist in subjects with diabetes and COVID-19 pneumonia", "author": "Dispinseri", "doi-asserted-by": "crossref", "first-page": "1472", "journal-title": "J Clin Endocrinol Metab", "key": "10.1016/j.diabres.2023.110692_b0055", "volume": "106", "year": "2021" }, { "DOI": "10.3132/dvdr.2008.027", "doi-asserted-by": "crossref", "key": "10.1016/j.diabres.2023.110692_b0060", "unstructured": "Scarpello JH, Howlett HC. Metformin therapy and clinical uses. Diab Vasc Dis Res 2008;5:157–67. https://doi: 10.3132/dvdr.2008.027." }, { "DOI": "10.1161/CIRCRESAHA.116.308445", "article-title": "Anti-inflammatory effects of metformin irrespective of diabetes status", "author": "Cameron", "doi-asserted-by": "crossref", "first-page": "652", "journal-title": "Circ Res", "key": "10.1016/j.diabres.2023.110692_b0065", "volume": "119", "year": "2016" }, { "DOI": "10.1016/j.ejphar.2021.173934", "article-title": "Metformin turns 62 in pharmacotherapy: emergence of non-glycaemic effects and potential novel therapeutic applications", "author": "Mbara", "doi-asserted-by": "crossref", "journal-title": "Eur J Pharmacol", "key": "10.1016/j.diabres.2023.110692_b0070", "volume": "898", "year": "2021" }, { "DOI": "10.1038/s41598-022-07294-1", "article-title": "Metformin use and the risk of bacterial pneumonia in patients with type 2 diabetes", "author": "Yen", "doi-asserted-by": "crossref", "first-page": "3270", "journal-title": "Sci Rep", "key": "10.1016/j.diabres.2023.110692_b0075", "volume": "12", "year": "2022" }, { "DOI": "10.1186/s13054-019-2346-4", "article-title": "Association of preadmission metformin use and mortality in patients with sepsis and diabetes mellitus: a systematic review and meta-analysis of cohort studies", "author": "Liang", "doi-asserted-by": "crossref", "first-page": "50", "journal-title": "Crit Care", "key": "10.1016/j.diabres.2023.110692_b0080", "volume": "23", "year": "2019" }, { "article-title": "Metformin in patients with COVID-19: a systematic review and meta-analysis", "author": "Li", "journal-title": "Front Med (Lausanne)", "key": "10.1016/j.diabres.2023.110692_b0085", "volume": "8", "year": "2021" }, { "DOI": "10.1016/j.vaccine.2017.03.078", "article-title": "Metformin improves in vivo and in vitro B cell function in individuals with obesity and type-2 diabetes", "author": "Diaz", "doi-asserted-by": "crossref", "first-page": "2694", "journal-title": "Vaccine", "key": "10.1016/j.diabres.2023.110692_b0090", "volume": "35", "year": "2017" }, { "DOI": "10.3390/vaccines10101752", "article-title": "Metformin use before influenza vaccination may lower the risks of influenza and related complications", "author": "Yen", "doi-asserted-by": "crossref", "first-page": "1752", "journal-title": "Vaccines (Basel)", "key": "10.1016/j.diabres.2023.110692_b0095", "volume": "10", "year": "2022" }, { "article-title": "Long-term cardiovascular outcomes in COVID-19 survivors among non-vaccinated population: a retrospective cohort study from the TriNetX US collaborative networks", "author": "Wang", "journal-title": "EClinicalMedicine", "key": "10.1016/j.diabres.2023.110692_b0100", "volume": "53", "year": "2022" }, { "DOI": "10.1056/NEJMoa2034577", "doi-asserted-by": "crossref", "key": "10.1016/j.diabres.2023.110692_b0105", "unstructured": "Polack FP, Thomas SJ, Kitchin N, Absalon J, Gurtman A, Lockhart S, et al. Safety and efficacy of the BNT162b2 mRNA Covid-19 vaccine. N Engl J Med 2020;383:2603–15. https://doi: 10.1056/NEJMoa2034577" }, { "DOI": "10.1126/scitranslmed.3009892", "article-title": "mTOR inhibition improves immune function in the elderly", "author": "Mannick", "doi-asserted-by": "crossref", "journal-title": "Sci Transl Med", "key": "10.1016/j.diabres.2023.110692_b0110", "year": "20146268179" }, { "DOI": "10.1002/jmv.28278", "article-title": "Metformin use and the risks of herpes zoster and postherpetic neuralgia in patients with type 2 diabetes", "author": "Yen", "doi-asserted-by": "crossref", "first-page": "e28278", "journal-title": "J Med Virol", "key": "10.1016/j.diabres.2023.110692_b0115", "volume": "95", "year": "2023" }, { "DOI": "10.1016/j.metop.2021.100137", "article-title": "A review on protective roles and potential mechanisms of metformin in diabetic patients diagnosed with COVID-19", "author": "Kifle", "doi-asserted-by": "crossref", "journal-title": "Metabol Open", "key": "10.1016/j.diabres.2023.110692_b0120", "volume": "12", "year": "2021" }, { "DOI": "10.1016/j.diabres.2020.108183", "article-title": "Metformin in COVID-19: a possible role beyond diabetes", "author": "Sharma", "doi-asserted-by": "crossref", "journal-title": "Diabetes Res Clin Pract", "key": "10.1016/j.diabres.2023.110692_b0125", "volume": "164", "year": "2020" }, { "DOI": "10.1016/S1473-3099(22)00320-6", "article-title": "Global impact of the first year of COVID-19 vaccination: a mathematical modelling study", "author": "Watson", "doi-asserted-by": "crossref", "first-page": "1293", "journal-title": "Lancet Infect Dis", "key": "10.1016/j.diabres.2023.110692_b0130", "volume": "22", "year": "2022" }, { "DOI": "10.1016/S2666-7568(20)30033-7", "article-title": "Metformin and risk of mortality in patients hospitalised with COVID-19: a retrospective cohort analysis", "author": "Bramante", "doi-asserted-by": "crossref", "first-page": "e34", "journal-title": "Lancet Healthy Longev", "key": "10.1016/j.diabres.2023.110692_b0135", "volume": "2", "year": "2021" }, { "DOI": "10.1056/NEJMoa2201662", "article-title": "Randomized trial of Metformin, Ivermectin, and Fluvoxamine for Covid-19", "author": "Bramante", "doi-asserted-by": "crossref", "first-page": "599", "journal-title": "N Engl J Med", "key": "10.1016/j.diabres.2023.110692_b0140", "volume": "387", "year": "2022" }, { "article-title": "Mast cells contribute to coronavirus-induced inflammation: new anti-inflammatory strategy", "author": "Kritas", "first-page": "9", "journal-title": "J Biol Regul Homeost Agents", "key": "10.1016/j.diabres.2023.110692_b0145", "volume": "34", "year": "2020" } ], "reference-count": 29, "references-count": 29, "relation": {}, "resource": { "primary": { "URL": "https://linkinghub.elsevier.com/retrieve/pii/S0168822723004540" } }, "score": 1, "short-title": [], "source": "Crossref", "subject": [ "Endocrinology", "General Medicine", "Endocrinology, Diabetes and Metabolism", "Internal Medicine" ], "subtitle": [], "title": "Metformin use before COVID-19 vaccination and the risks of COVID-19 incidence, medical utilization, and all-cause mortality in patients with type 2 diabetes mellitus", "type": "journal-article", "update-policy": "http://dx.doi.org/10.1016/elsevier_cm_policy" }