Efficacy of nasal irrigation and oral rinse with sodium bicarbonate solution on virus clearance for COVID-19 patients
et al., Frontiers in Public Health, doi:10.3389/fpubh.2023.1145669
, Efficacy of nasal irrigation and oral rinse with sodium bicarbonate solution on virus clearance for COVID-19.., Frontiers in Public Health, doi:10.3389/fpubh.2023.1145669
RCT 55 mild/moderate patients in China, showing shorter hospitalization with sodium bicarbonate nasal irrigation and oral rinsing. Oral rinse with 5% sodium bicarbonate solution three times daily. Nasal irrigation two times with the solution entering through one nostril and exiting from the other. 30–40mL of solution was used every time and irrigation was performed for at least 30s. Details of randomization are not provided.
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hospitalization time, 38.5% lower, relative time 0.61, p < 0.001, treatment mean 7.7 (±4.15) n=23, control mean 12.53 (±5.56) n=32.
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| Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates |
Wang et al., 15 Mar 2023, Randomized Controlled Trial, China, peer-reviewed, 13 authors.
Late treatment
is less effective
is less effective
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