Hepatic and gastrointestinal disturbances in Egyptian patients infected with coronavirus disease 2019: A multicentre cohort study
et al., World Journal of Gastroenterology,
Retrospective 547 hospitalized COVID+ patients in Egypt, showing lower mortality with vitamin C treatment. Treatment was applied according to the official guidelines, indicating that vitamin C was co-administered with HCQ. Actual treatment counts suggest that vitamin C treatment was typically co-administered with CQ or HCQ, with CQ being more common. The strong efficacy may be partly due to HCQ/CQ which may not be fully accounted for in analysis due to the split between HCQ/CQ and the use of HCQ/CQ without vitamin C for severe cases.
risk of death, 94.2% lower, RR 0.06, p = 0.003, treatment 22 of 340 (6.5%), control 31 of 207 (15.0%), adjusted per study, odds ratio converted to relative risk, multivariable.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Shousha et al., 28 Oct 2021, retrospective, Egypt, peer-reviewed, 18 authors, study period 15 April, 2020 - 29 July, 2020.